Significant Ownership of RTW INVESTMENTS, LP

Signature - Title
/s/ Roderick Wong, M.D. - Roderick Wong, M.D., Managing Partner
Location
New York, NY
Summary
This page shows a list of all the recent SCHEDULE 13D/G filings made by RTW INVESTMENTS, LP.

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Significant Ownership of RTW INVESTMENTS, LP

Sym Company Class Ownership Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
ALUR ALLURION TECHNOLOGIES, INC. Common Stock, par value $0.0001 per share 39% $8,542,574 5,891,430 0% RTW Investments, LP 26 Feb 2026
OBIO ORCHESTRA BIOMED HOLDINGS, INC. Common Stock, par value $0.0001 per share 20% $49,561,068 +$15,090,906 11,942,426 +44% RTW Investments, LP 23 Feb 2026
ALUR ALLURION TECHNOLOGIES, INC. Common Stock, $0.0001 par value per share 18% $451,523 1,050,053 0% RTW Investments, LP 20 Feb 2025
ESTA Establishment Labs Holdings Inc. Common Shares, No Par Value 10% $84,073,815 2,822,216 RTW Investments, LP 31 Dec 2024
STOK Stoke Therapeutics, Inc. Common Stock, par value $0.0001 per share 10% $50,498,414 5,310,033 RTW Investments, LP 31 Dec 2024
NGNE Neurogene Inc. Common Stock, par value $0.000001 per share 10% $23,096,955 1,498,829 RTW Investments, LP 31 Dec 2024
VSTM Verastem, Inc. Common Stock, $0.0001 par value 9.9% $60,496,591 +$17,057,672 7,836,346 +39% RTW Investments, LP 31 Dec 2025
CMPS COMPASS Pathways plc Ordinary Shares, par value GBP 0.008 per share 9.9% $34,865,781 +$5,877,137 9,474,397 +20% RTW Investments, LP 30 Jun 2025
MIST MILESTONE PHARMACEUTICALS INC. Common Shares, no par value per share 9.9% $18,310,336 +$7,029,150 9,155,168 +62% RTW Investments, LP 30 Sep 2025
TENX Tenax Therapeutics, Inc. Common Stock, $0.0001 par value 9.9% $9,797,068 +$3,499,546 650,968 +56% RTW Investments, LP 31 Dec 2025
GHRS GH Research PLC Ordinary shares, nominal value $0.025 per share 8.9% $52,412,799 5,499,769 RTW Investments, LP 31 Mar 2025
RAPT Rapt Therapeutics, Inc. Common Stock, $0.0001 par value per share 8.9% $10,234,680 11,764,000 RTW Investments, LP 31 Mar 2025
XNCR Xencor Inc Common Stock, $0.01 par value 8.7% $72,972,963 6,221,054 RTW Investments, LP 30 Sep 2025
IMTX Immatics N.V. Ordinary Shares, nominal value (euro) 0.01 per share 8.5% $120,050,217 +$27,486,238 11,433,354 +30% RTW Investments, LP 31 Dec 2025
TSHA TAYSHA GENE THERAPIES, INC. Common Stock, par value $0.00001 per share 8.3% $120,312,664 -$9,129,432 23,407,133 -7.1% RTW Investments, LP 31 Dec 2025
REPL Replimune Group, Inc. Common Stock, $0.001 par value 8.2% $26,798,117 6,395,732 RTW Investments, LP 30 Sep 2025
PTGX Protagonist Therapeutics, Inc Common Stock, $0.00001 par value 8.1% $405,989,003 5,059,053 RTW Investments, LP 31 Dec 2025
TARS Tarsus Pharmaceuticals, Inc. Common Stock, par value $0.0001 per share 8.1% $134,159,372 3,424,180 RTW Investments, LP 30 Jun 2025
CSTL CASTLE BIOSCIENCES, INC. Common Stock, $0.001 par value 7.2% $84,757,547 2,115,237 RTW Investments, LP 31 Dec 2025
ZLAB Zai Lab Limited Ordinary Shares, par value $0.000006 per share 6.3% $1,258,888,889 +$844,379,694 69,590,320 +204% RTW Investments, LP 31 Dec 2025
SYRE Spyre Therapeutics, Inc. Common Stock, par value $0.0001 per share 6.2% $54,402,380 3,621,996 RTW Investments, LP 31 Dec 2024
APLS Apellis Pharmaceuticals, Inc. Common Stock, $0.0001 par value 6.1% $163,532,076 7,666,764 RTW Investments, LP 31 Dec 2025
QURE uniQure N.V. Ordinary Shares, par value 0.05 euro 6% $86,811,096 -$16,688,905 3,711,462 -16% RTW Investments, LP 31 Dec 2025
RAPT RAPT THERAPEUTICS, INC. Common Stock, $0.0001 par value 5.9% $55,041,487 1,637,165 RTW Investments, LP 31 Dec 2025
BBNX BETA BIONICS, INC. Common Stock, $0.0001 par value 5.7% $50,350,000 -$16,109,362 2,500,000 -24% RTW Investments, LP 31 Dec 2025
KLRS KALARIS THERAPEUTICS, INC. Common Stock, $0.0001 par value 5.7% $12,714,000 1,300,000 RTW Investments, LP 31 Dec 2025
AQST Aquestive Therapeutics, Inc. Common Stock, $0.001 par value 5.2% $34,937,500 6,250,000 RTW Investments, LP 30 Sep 2025
RDNT RadNet, Inc. Common Stock, $0.0001 par value 5.1% $300,704,475 3,938,500 RTW Investments, LP 31 Dec 2025
APGE APOGEE THERAPEUTICS, INC. Common Stock, $0.00001 par value 4.9% $214,255,663 2,712,097 0% RTW Investments, LP 31 Dec 2025
SAGE Sage Therapeutics, Inc. Common Stock, par value $0.0001 per share 4.9% $23,388,462 3,002,370 RTW Investments, LP 31 Dec 2024
XGN Exagen Inc. Common Stock, par value $0.001 per share 4.9% $6,984,509 -$3,332,436 1,148,768 -32% RTW Investments, LP 31 Dec 2025
ORKA ORUKA THERAPEUTICS, INC. Common Stock, $0.001 par value 4.3% $62,382,466 +$3,409,845 2,058,148 +5.8% RTW Investments, LP 31 Dec 2025
ACAD ACADIA PHARMACEUTICALS INC. Common Stock, $0.0001 par value 4.2% $152,464,142 -$33,311,249 7,144,524 -18% RTW Investments, LP 30 Sep 2025
SABS SAB Biotherapeutics, Inc. Common Stock, $0.0001 par value 3.2% $6,253,970 +$2,218,090 1,587,302 +55% RTW Investments, LP 31 Dec 2025
RNA Avidity Biosciences, Inc. Common Stock, par value $0.0001 per share 3.1% $204,173,813 4,686,110 RTW Investments, LP 27 Oct 2025
AXSM Axsome Therapeutics, Inc. Common Stock, $0.0001 par value per share 3.1% $165,312,089 -$153,206,917 1,516,903 -48% RTW Investments, LP 30 Jun 2025
MRUS Merus N.V. Common Shares, nominal value (euro) 0.09 per share 2.7% $190,679,830 2,025,277 RTW Investments, LP 30 Sep 2025
EPIX ESSA Pharma Inc. Common Shares, no par value 2.5% $2,003,404 1,113,002 RTW Investments, LP 31 Dec 2024
DYN Dyne Therapeutics, Inc. Common Stock, $0.0001 par value per share 1.5% $18,782,199 -$39,196,902 1,690,567 -68% RTW Investments, LP 31 Mar 2025
ETNB 89bio, Inc. Common Stock, par value $0.001 per share 1.3% $13,575,936 1,967,527 RTW Investments, LP 31 Mar 2025
IMUX Immunic, Inc. Common Stock, par value $0.0001 per share 1.1% $1,170,509 1,026,762 RTW Investments, LP 31 Mar 2025
CUTRQ Cutera, Inc. Common Stock, $0.001 par value 0% $0 0 RTW Investments, LP 31 Dec 2024
GERN Geron Corporation Common Stock, $0.001 par value 0% $0 0 RTW Investments, LP 31 Dec 2024
PEPG PepGen Inc. Common Stock, $0.0001 par value per share 0% $0 -$5,108,955 0 -100% RTW Investments, LP 31 Mar 2025
CRGX CARGO THERAPEUTICS, INC. Common stock, par value $0.001 per share 0% $0 -$13,656,132 0 -100% RTW Investments, LP 30 Sep 2025
AKRO Akero Therapeutics, Inc. Common Stock, par value $0.0001 per share 0% $0 -$238,651,886 0 -100% RTW Investments, LP 31 Dec 2025
ALEC Alector, Inc. Common Stock, $0.0001 par value 0% $0 -$13,002,899 0 -100% RTW Investments, LP 31 Dec 2025

Schedules 13D/G Reported by RTW INVESTMENTS, LP:

Sym Target Class Ownership Change Current Shares Change Value Reporting name Form Report Period Filing Date
* An asterisk sign (*) next to the price indicates that the price is likely invalid.