| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| BAKER BROS. ADVISORS LP | 14.3% | $100M | 11M | Baker Bros. Advisors LP | 07 Mar 2025 | |||
| PRICE T ROWE ASSOCIATES INC /MD/ | 10.6% | $34.8M | 8.31M | T. Rowe Price Associates, Inc. | 30 Sep 2025 | |||
| RTW INVESTMENTS, LP | 8.2% | $26.8M | 6.4M | RTW Investments, LP | 30 Sep 2025 | |||
| Forbion Capital Fund III Cooperatief U.A. | 6.1% | $38.2M | 4.22M | Forbion Capital Fund III Cooperatief U.A. | 31 Dec 2024 | |||
| Point72 Asset Management, L.P. | 4.7% | -16.7% | $15.2M | -$3.49M | 3.63M | -18.7% | Point72 Asset Management, L.P. | 30 Sep 2025 |
| VANGUARD GROUP INC | 4.77% | $32.5M | 3.6M | The Vanguard Group | 31 Dec 2024 | |||
| Redmile Group, LLC | 0.7% | -95% | $2.25M | -$18.3M | 536K | -89.1% | Redmile Group, LLC | 30 Sep 2025 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Change | Price | Investors |
|---|---|---|---|---|---|
| 2025 Q3 | 82.9M | $348M | -$50M | $4.19 | 160 |
| 2025 Q2 | 81M | $752M | -$9.72M | $9.29 | 173 |
| 2025 Q1 | 82M | $799M | +$36.9M | $9.75 | 165 |
| 2024 Q4 | 77.9M | $943M | +$80.8M | $12.11 | 155 |
| 2024 Q3 | 69.9M | $767M | -$7.69M | $10.96 | 143 |
| 2024 Q2 | 70.9M | $638M | +$37.4M | $9.00 | 148 |
| 2024 Q1 | 67M | $547M | +$8.62M | $8.17 | 147 |
| 2023 Q4 | 66M | $557M | -$40.6M | $8.43 | 138 |
| 2023 Q3 | 56.8M | $971M | +$32.5M | $17.11 | 126 |
| 2023 Q2 | 54.6M | $1.27B | +$26.6M | $23.22 | 139 |
| 2023 Q1 | 53.8M | $949M | +$90.9M | $17.66 | 138 |
| 2022 Q4 | 48.2M | $1.31B | +$189M | $27.20 | 135 |
| 2022 Q3 | 40.8M | $704M | -$8.66M | $17.27 | 103 |
| 2022 Q2 | 40M | $700M | +$18M | $17.48 | 98 |
| 2022 Q1 | 39.1M | $665M | -$35.5M | $16.98 | 104 |
| 2021 Q4 | 38.8M | $1.05B | +$5.6M | $27.10 | 97 |
| 2021 Q3 | 35.4M | $1.05B | +$5.53M | $29.64 | 99 |
| 2021 Q2 | 34.9M | $1.34B | -$5.48M | $38.42 | 109 |
| 2021 Q1 | 34.7M | $1.06B | +$1.01M | $30.51 | 106 |
| 2020 Q4 | 34.5M | $1.32B | +$362M | $38.15 | 112 |
| 2020 Q3 | 26.6M | $612M | +$25.7M | $23.02 | 78 |
| 2020 Q2 | 25.4M | $631M | +$87.7M | $24.85 | 75 |
| 2020 Q1 | 22.2M | $221M | -$471K | $9.97 | 56 |
| 2019 Q4 | 22M | $316M | +$48.2M | $14.35 | 61 |
| 2019 Q3 | 18.6M | $258M | -$14.8M | $13.90 | 51 |
| 2019 Q2 | 19.6M | $287M | +$6.76M | $14.66 | 53 |
| 2019 Q1 | 19.1M | $291M | +$17.7M | $15.22 | 53 |
| 2018 Q4 | 18.2M | $182M | +$1.49M | $10.00 | 50 |
| 2018 Q3 | 17.9M | $289M | +$289M | $16.10 | 54 |