Security Snapshot

CASTLE BIOSCIENCES INC - Common Stock, $0.001 par value per share (CSTL) Institutional Ownership

CUSIP: 14843C105

13F Institutional Holders and Ownership History from Q3 2019 to Q1 2026

Latest Period

Q1 2026

Institutions Reporting

185

Shares (Excl. Options)

27,584,532

Price

$24.55

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Latest holder snapshot 5 signals
Portfolio coverage rank
0%
Share change
+264,200
Value change
-$6,568,681
Number of holders
185
Issuer context Names, identifiers, and filing context for this profile. 3 identity fields
Shares outstanding
30,343,438
SEC-reported price per share
$24.81
Insider filing price
$24.81
13F Shares, Excluding Options vs Price
13F Value, Excluding Options
Total Investors

Key facts

  • CSTL - CASTLE BIOSCIENCES INC - Common Stock, $0.001 par value per share is tracked under CUSIP 14843C105.
  • 185 institutions reported positions in Q1 2026.
  • 5 significant owners is listed from Schedule 13D/13G reporting.

Change

  • Holder count moved from 196 to 185 between Q4 2025 and Q1 2026.
  • SEC-reported value moved from $1,062,104,151 to $676,774,947.

Research use

  • You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
  • 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.

Evidence

Source: SEC Form 13F

Latest holder context comes from 185 institutions filings for Q1 2026.

Open SEC evidence

Security key

14843C105

Latest holder period

Q1 2026

13F holders

185

13D/G owners

5

CIK / CUSIP context first

13D/G owners

Significant owners

Large-stake holder rows connected to Schedule 13D/G evidence.

Rows
5
Security
CSTL
Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
RTW INVESTMENTS, LP 9.3% +30% $67,717,124 +$15,788,056 2,758,335 +30% RTW Investments, LP 31 Mar 2026
BlackRock, Inc. 8.2% $47,017,281 2,338,005 BlackRock, Inc. 31 Mar 2025
Portolan Capital Management, LLC 4.4% -20% $33,149,448 -$6,403,033 1,350,283 -16% Portolan Capital Management, LLC 31 Mar 2026
DIMENSIONAL FUND ADVISORS LP 3.9% -24% $44,494,010 -$12,848,347 1,143,799 -22% Dimensional Fund Advisors LP 31 Dec 2025
WASATCH ADVISORS LP 3.5% $20,078,930 998,455 WASATCH ADVISORS LP 31 Mar 2025

As of 31 Mar 2026, 185 institutional investors reported holding 27,584,532 shares of CASTLE BIOSCIENCES INC - Common Stock, $0.001 par value per share (CSTL). This represents 91% of the company’s total 30,343,438 outstanding shares.

13F concentration

Top 25 institutional shareholders

Largest 13F positions for this security by reported shares and value.

Top holder share
70%
Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
BlackRock, Inc. 9.8% 2,982,946 -3.9% 0% $73,231,325
RTW INVESTMENTS, LP 9.1% 2,758,335 +30% 0.67% $67,717,124
PRINCIPAL FINANCIAL GROUP INC 5.8% 1,769,877 -2.1% 0.02% $43,450,481
Portolan Capital Management, LLC 4.5% 1,350,283 -22% 1.8% $33,149,448
VANGUARD CAPITAL MANAGEMENT LLC 3.9% 1,177,522 0% 0% $28,908,165
DIMENSIONAL FUND ADVISORS LP 3.4% 1,039,761 -9.1% 0.01% $25,523,454
SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC 3.1% 940,685 -11% 1.1% $23,093,817
VANGUARD PORTFOLIO MANAGEMENT LLC 2.8% 861,771 0% 0% $21,156,478
Allianz Asset Management GmbH 2.7% 811,324 +30% 0.02% $19,918,004
STATE STREET CORP 2.5% 769,079 +4.4% 0% $18,880,889
GEODE CAPITAL MANAGEMENT, LLC 2.4% 728,100 +1.8% 0% $17,878,555
AIGH Capital Management LLC 1.9% 590,601 -5.5% 3% $14,499,255
Qube Research & Technologies Ltd 1.8% 559,583 +138% 0.02% $13,737,763
PALISADE CAPITAL MANAGEMENT, LP 1.8% 535,884 -5.6% 0.44% $13,155,952
RENAISSANCE TECHNOLOGIES LLC 1.8% 532,800 +8.1% 0.02% $13,080,240
Nuveen, LLC 1.7% 522,127 -0.49% 0% $12,818,217
ACADIAN ASSET MANAGEMENT LLC 1.6% 484,441 +24% 0.02% $11,884,000
WASATCH ADVISORS LP 1.5% 455,036 -15% 0.07% $11,171,134
MORGAN STANLEY 1.4% 428,934 +111% 0% $10,530,333
EVENTIDE ASSET MANAGEMENT, LLC 1.3% 386,425 +27% 0.16% $9,486,734
Connor, Clark & Lunn Investment Management Ltd. 1.2% 377,082 -2.9% 0.02% $9,257,363
MILLENNIUM MANAGEMENT LLC 1.2% 353,319 +14% 0.01% $8,673,981
GOLDMAN SACHS GROUP INC 1.1% 341,171 +19% 0% $8,375,748
SCHRODER INVESTMENT MANAGEMENT GROUP 0.99% 298,941 -39% 0.01% $7,040,061
NORTHERN TRUST CORP 0.9% 273,101 +4.1% 0% $6,704,630

Quarter history

Institutional holders across reporting periods

Holder count, reported shares/value, and median price by quarter.

Periods
27
Latest
Q1 2026
Rows shown
1-25 of 27
Period 13F Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2026 Q1 27,584,532 $676,774,947 -$6,568,681 $24.55 185
2025 Q4 27,312,273 $1,062,104,151 +$35,010,645 $38.90 196
2025 Q3 26,525,698 $603,808,247 +$704,267 $22.77 170
2025 Q2 26,536,136 $541,803,165 +$16,367,707 $20.42 151
2025 Q1 25,785,418 $516,159,447 -$22,608,207 $20.02 180
2024 Q4 26,505,010 $706,396,254 +$8,987,296 $26.65 197
2024 Q3 25,823,597 $736,872,924 +$15,687,154 $28.52 185
2024 Q2 25,237,547 $549,387,569 +$5,246,303 $21.77 158
2024 Q1 24,977,542 $553,239,171 +$24,692,740 $22.15 148
2023 Q4 23,883,435 $515,429,989 +$17,867,692 $21.58 150
2023 Q3 23,151,664 $391,032,725 +$7,780,165 $16.89 133
2023 Q2 22,797,205 $312,778,898 -$3,698,099 $13.72 128
2023 Q1 22,094,408 $501,938,865 +$5,568,015 $22.72 148
2022 Q4 22,279,170 $524,435,055 +$5,715,957 $23.54 152
2022 Q3 21,906,465 $571,186,085 -$14,799,148 $26.08 152
2022 Q2 22,558,449 $495,033,707 -$115,268,932 $21.95 141
2022 Q1 22,780,568 $1,019,269,661 +$62,738,499 $44.86 153
2021 Q4 21,449,510 $918,308,511 -$59,908,643 $42.87 153
2021 Q3 20,974,973 $1,396,164,362 +$40,585,506 $66.50 182
2021 Q2 20,801,213 $1,521,315,172 -$4,483,937 $73.33 176
2021 Q1 21,328,263 $1,459,495,488 +$90,506,347 $68.46 173
2020 Q4 19,063,994 $1,280,953,552 +$376,683,100 $67.15 160
2020 Q3 13,395,783 $689,395,356 +$88,062,594 $51.45 144
2020 Q2 11,747,525 $443,283,646 +$169,050,988 $37.69 125
2020 Q1 7,359,714 $219,391,385 +$66,312,670 $29.81 88
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