Security Snapshot

CASTLE BIOSCIENCES INC - Common Stock, $0.001 par value per share (CSTL) Institutional Ownership

CUSIP: 14843C105

13F Institutional Holders and Ownership History from Q3 2019 to Q2 2026

Latest Period

Q2 2026

Institutions Reporting

176

Shares (Excl. Options)

27,409,761

Price

$23.85

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Latest holder snapshot 5 signals
Portfolio coverage rank
0%
Share change
-147,945
Value change
-$4,058,873
Number of holders
176
Issuer context Names, identifiers, and filing context for this profile. 3 identity fields
Shares outstanding
30,343,438
SEC-reported price per share
$32.35
Insider filing price
$32.35
13F Shares, Excluding Options vs Price
13F Value, Excluding Options
Total Investors

Key facts

  • CSTL - CASTLE BIOSCIENCES INC - Common Stock, $0.001 par value per share is tracked under CUSIP 14843C105.
  • 176 institutions reported positions in Q2 2026.
  • 5 significant owners is listed from Schedule 13D/13G reporting.

Change

  • Holder count moved from 185 to 176 between Q1 2026 and Q2 2026.
  • SEC-reported value moved from $676,774,747 to $653,821,675.

Research use

  • You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
  • 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.

Evidence

Source: SEC Form 13F

Latest holder context comes from 176 institutions filings for Q2 2026.

Open SEC evidence

Security key

14843C105

Latest holder period

Q2 2026

13F holders

176

13D/G owners

5

CIK / CUSIP context first

13D/G owners

Significant owners

Large-stake holder rows connected to Schedule 13D/G evidence.

Rows
5
Security
CSTL
Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
RTW INVESTMENTS, LP 9.3% +30% $67,717,124 +$15,788,056 2,758,335 +30% RTW Investments, LP 31 Mar 2026
BlackRock, Inc. 8.2% $47,017,281 2,338,005 BlackRock, Inc. 31 Mar 2025
Portolan Capital Management, LLC 4.4% -20% $33,149,448 -$6,403,033 1,350,283 -16% Portolan Capital Management, LLC 31 Mar 2026
DIMENSIONAL FUND ADVISORS LP 3.9% -24% $44,494,010 -$12,848,347 1,143,799 -22% Dimensional Fund Advisors LP 31 Dec 2025
WASATCH ADVISORS LP 3.5% $20,078,930 998,455 WASATCH ADVISORS LP 31 Mar 2025

As of 30 Jun 2026, 176 institutional investors reported holding 27,409,761 shares of CASTLE BIOSCIENCES INC - Common Stock, $0.001 par value per share (CSTL). This represents 90% of the company’s total 30,343,438 outstanding shares.

13F concentration

Top 25 institutional shareholders

Largest 13F positions for this security by reported shares and value.

Top holder share
68%
Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
BlackRock, Inc. 11% 3,291,963 +10% 0% $78,513,319
RTW INVESTMENTS, LP 9.2% 2,778,335 +0.73% 0.57% $66,263,290
PRINCIPAL FINANCIAL GROUP INC 5.7% 1,726,648 -2.4% 0.02% $41,180,555
VANGUARD CAPITAL MANAGEMENT LLC 4% 1,226,497 +4.2% 0% $29,251,953
ACADIAN ASSET MANAGEMENT LLC 3% 918,668 +90% 0.03% $21,897,000
Allianz Asset Management GmbH 2.9% 879,258 +8.4% 0.02% $20,970,303
VANGUARD PORTFOLIO MANAGEMENT LLC 2.8% 840,785 -2.4% 0% $20,052,722
SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC 2.7% 824,872 -12% 0.51% $19,673,197
STATE STREET CORP 2.7% 822,079 +6.9% 0% $19,630,772
GEODE CAPITAL MANAGEMENT, LLC 2.6% 795,912 +9.3% 0% $18,986,390
MACKENZIE FINANCIAL CORP 2.6% 793,507 +971% 0.02% $18,925,142
DIMENSIONAL FUND ADVISORS LP 2.6% 791,085 -24% 0% $18,868,635
Jefferies Financial Group Inc. 2.1% 647,391 0.14% $15,440,275
Qube Research & Technologies Ltd 1.9% 589,300 +5.3% 0.02% $14,054,805
AIGH Capital Management LLC 1.8% 545,101 -7.7% 1.2% $13,000,659
RENAISSANCE TECHNOLOGIES LLC 1.2% 371,200 -30% 0.01% $8,853,120
GOLDMAN SACHS GROUP INC 1.2% 358,397 +5% 0% $8,547,768
Point72 Asset Management, L.P. 1.2% 357,317 0.01% $8,522,010
KENNEDY CAPITAL MANAGEMENT LLC 1.1% 348,371 0.15% $8,308,648
Connor, Clark & Lunn Investment Management Ltd. 1.1% 331,727 -12% 0.01% $7,911,689
MORGAN STANLEY 1.1% 329,684 -23% 0% $7,862,987
Portolan Capital Management, LLC 1.1% 328,818 -76% 0.29% $7,842,309
PANAGORA ASSET MANAGEMENT INC 0.99% 301,040 +35% 0.02% $7,179,804
Allspring Global Investments Holdings, LLC 0.96% 292,470 +82% 0.01% $6,975,410
NORTHERN TRUST CORP 0.94% 285,158 +4.4% 0% $6,801,019

Quarter history

Institutional holders across reporting periods

Holder count, reported shares/value, and median price by quarter.

Periods
28
Latest
Q2 2026
Rows shown
1-25 of 28
Period 13F Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2026 Q2 27,409,761 $653,821,675 -$4,058,873 $23.85 176
2026 Q1 27,584,532 $676,774,747 -$6,568,772 $24.55 185
2025 Q4 27,312,273 $1,062,104,151 +$35,010,645 $38.90 196
2025 Q3 26,525,698 $603,808,247 +$704,267 $22.77 170
2025 Q2 26,536,136 $541,803,165 +$16,367,707 $20.42 151
2025 Q1 25,785,418 $516,159,447 -$22,608,207 $20.02 180
2024 Q4 26,505,010 $706,396,254 +$8,987,296 $26.65 197
2024 Q3 25,823,597 $736,872,924 +$15,687,154 $28.52 185
2024 Q2 25,237,547 $549,387,569 +$5,246,303 $21.77 158
2024 Q1 24,977,542 $553,239,171 +$24,692,740 $22.15 148
2023 Q4 23,883,435 $515,429,989 +$17,867,692 $21.58 150
2023 Q3 23,151,664 $391,032,725 +$7,780,165 $16.89 133
2023 Q2 22,797,205 $312,778,898 -$3,698,099 $13.72 128
2023 Q1 22,094,408 $501,938,865 +$5,568,015 $22.72 148
2022 Q4 22,279,170 $524,435,055 +$5,715,957 $23.54 152
2022 Q3 21,906,465 $571,186,085 -$14,799,148 $26.08 152
2022 Q2 22,558,449 $495,033,707 -$115,268,932 $21.95 141
2022 Q1 22,780,568 $1,019,269,661 +$62,738,499 $44.86 153
2021 Q4 21,449,510 $918,308,511 -$59,908,643 $42.87 153
2021 Q3 20,974,973 $1,396,164,362 +$40,585,506 $66.50 182
2021 Q2 20,801,213 $1,521,315,172 -$4,483,937 $73.33 176
2021 Q1 21,328,263 $1,459,495,488 +$90,506,347 $68.46 173
2020 Q4 19,063,994 $1,280,953,552 +$376,683,100 $67.15 160
2020 Q3 13,395,783 $689,395,356 +$88,062,594 $51.45 144
2020 Q2 11,747,525 $443,283,646 +$169,050,988 $37.69 125
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