Security Snapshot

Dyne Therapeutics, Inc. - COMMON STOCK (DYN) Institutional Ownership

CUSIP: 26818M108

13F Institutional Holders and Ownership History from Q3 2020 to Q1 2026

Latest Period

Q4 2025

Institutions Reporting

230

Shares (Excl. Options)

177,888,919

Price

$19.56

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Type / Class
Equity / COMMON STOCK
Symbol
DYN on Nasdaq
Shares outstanding
164,981,109
Price per share
$18.10
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
177,888,919
Total reported value
$3,479,390,610
% of total 13F portfolios
0.01%
Share change
+22,989,320
Value change
+$511,413,657
Number of holders
230
Price from insider filings
$18.10
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Quick Takeaways

  • DYN - Dyne Therapeutics, Inc. - COMMON STOCK is tracked under CUSIP 26818M108.
  • 230 institutions reported positions in Q4 2025.
  • 8 significant owners is listed from Schedule 13D/13G reporting.

What Changed

  • Holder count moved from 230 to 76 between Q4 2025 and Q1 2026.
  • Reported value moved from $3,479,390,610 to $336,224,315.

Why This Matters

  • You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
  • 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.

Source Evidence

Source: SEC Form 13F

Latest holder context comes from 230 institutions filings for Q4 2025.

Open SEC Evidence

Investment Quick Answers

What is CUSIP 26818M108?
CUSIP 26818M108 identifies DYN - Dyne Therapeutics, Inc. - COMMON STOCK in SEC 13F datasets.

Where can I see the latest institutional holders?
Review the Q4 2025 holders report and the ownership history table below.

Significant Owners of Dyne Therapeutics, Inc. - COMMON STOCK (DYN) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
T. Rowe Price Investment Management, Inc. 16% +50% $425,254,992 +$144,613,568 26,578,437 +52% T. Rowe Price Investment Management, Inc. 28 Feb 2026
JANUS HENDERSON GROUP PLC 8.5% -19% $251,645,523 -$15,543,028 13,887,722 -5.8% JANUS HENDERSON GROUP PLC 31 Dec 2025
FMR LLC 5.4% +16% $161,252,536 +$67,217,717 8,908,980 +71% FMR LLC 31 Mar 2026
BlackRock, Inc. 5.8% $73,080,236 6,577,879 BlackRock, Inc. 31 Mar 2025
Atlas Venture Fund XI, L.P. 4% $72,275,396 5,713,470 Atlas Venture Associates XI, L.P. 30 Sep 2025
Forbion Capital Fund IV Cooperatief U.A. 4.8% $60,000,055 5,400,545 ForDyne B.V. 31 Mar 2025
RTW INVESTMENTS, LP 1.5% -72% $18,782,199 -$39,196,902 1,690,567 -68% RTW Investments, LP 31 Mar 2025
Point72 Asset Management, L.P. 1.5% -72% $18,546,390 -$39,187,803 1,669,342 -68% Point72 Asset Management, L.P. 31 Mar 2025

As of 31 Dec 2025, 230 institutional investors reported holding 177,888,919 shares of Dyne Therapeutics, Inc. - COMMON STOCK (DYN). This represents 108% of the company’s total 164,981,109 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of Dyne Therapeutics, Inc. - COMMON STOCK (DYN) together control 82% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
T. Rowe Price Investment Management, Inc. 11% 17,540,089 +524% 0.22% $343,085,000
JANUS HENDERSON GROUP PLC 8.4% 13,887,722 -5.8% 0.12% $271,603,659
VANGUARD GROUP INC 6.8% 11,215,565 +15% 0% $219,376,451
BlackRock, Inc. 6.8% 11,190,838 +16% 0% $218,892,793
Atlas Venture Life Science Advisors, LLC 5.5% 9,130,465 0% 21% $178,591,895
STATE STREET CORP 4.1% 6,692,745 +27% 0% $130,910,092
FMR LLC 4% 6,569,921 +22% 0.01% $128,507,653
FCPM III SERVICES B.V. 3.3% 5,462,846 0% 14% $106,853,268
ADAGE CAPITAL PARTNERS GP, L.L.C. 3.1% 5,172,000 +46% 0.15% $101,164,320
Orbis Allan Gray Ltd 2.9% 4,801,928 0.39% $93,925,712
TCG Crossover Management, LLC 2.8% 4,615,144 0% 3% $90,272,217
JPMORGAN CHASE & CO 2.2% 3,549,909 +5.5% 0% $69,436,220
Siren, L.L.C. 2.1% 3,502,941 -26% 2% $68,517,526
PERCEPTIVE ADVISORS LLC 2.1% 3,478,944 +544% 1.2% $68,048,145
GEODE CAPITAL MANAGEMENT, LLC 2% 3,263,429 +14% 0% $63,844,380
ARMISTICE CAPITAL, LLC 2% 3,249,708 +6.1% 1.6% $63,564,288
Frazier Life Sciences Management, L.P. 1.9% 3,153,082 +16% 1.7% $61,674,284
Deep Track Capital, LP 1.6% 2,650,000 +32% 1.2% $51,834,000
Vivo Capital, LLC 1.6% 2,614,960 0% 3.3% $51,148,618
PRICE T ROWE ASSOCIATES INC /MD/ 1.4% 2,323,789 +66% 0% $45,454,000
GOLDMAN SACHS GROUP INC 1.4% 2,283,191 +20% 0.01% $44,659,216
Sofinnova Investments, Inc. 1.4% 2,254,161 +129% 1.9% $44,091,389
ORBIMED ADVISORS LLC 1.3% 2,202,184 -4.8% 0.92% $43,074,719
VR ADVISER, LLC 1.3% 2,173,913 0% 2.1% $42,521,738
FRANKLIN RESOURCES INC 1.2% 2,006,638 +43% 0.01% $39,249,837

Institutional Holders of Dyne Therapeutics, Inc. - COMMON STOCK (DYN) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2026 Q1 18,545,495 $336,224,315 -$2,648,513 $18.13 76
2025 Q4 177,888,919 $3,479,390,610 +$511,413,657 $19.56 230
2025 Q3 155,774,921 $1,970,440,035 +$381,733,004 $12.65 205
2025 Q2 128,553,808 $1,223,875,095 +$58,226,785 $9.52 195
2025 Q1 121,788,688 $1,284,331,056 -$75,923,327 $10.46 202
2024 Q4 111,635,776 $2,630,327,572 -$39,471,758 $23.56 199
2024 Q3 112,428,939 $4,033,469,001 -$6,349 $35.92 200
2024 Q2 110,972,098 $3,915,861,443 +$555,159,053 $35.29 191
2024 Q1 95,365,001 $2,707,385,907 +$786,881,972 $28.39 167
2023 Q4 69,922,072 $929,957,219 +$57,596,260 $13.30 123
2023 Q3 59,888,832 $536,594,556 +$1,685,315 $8.96 114
2023 Q2 59,189,838 $665,851,766 +$50,911,029 $11.25 117
2023 Q1 54,627,733 $628,721,822 +$56,536,368 $11.52 125
2022 Q4 49,732,095 $576,377,450 +$50,130,248 $11.59 112
2022 Q3 44,533,854 $565,571,380 -$9,010,573 $12.70 100
2022 Q2 46,679,856 $320,706,640 -$8,056,035 $6.87 87
2022 Q1 47,256,134 $455,432,690 -$4,233,139 $9.64 90
2021 Q4 47,794,946 $568,260,037 +$18,929,604 $11.89 90
2021 Q3 32,306,202 $524,727,164 -$16,367,213 $16.24 80
2021 Q2 35,805,078 $753,366,735 +$36,093,361 $21.04 75
2021 Q1 31,379,394 $487,292,000 +$72,426,450 $15.53 72
2020 Q4 26,339,155 $552,433,805 +$28,795,524 $21.00 67
2020 Q3 24,527,914 $493,744,000 +$493,744,015 $20.19 49
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