Latest Period
Q1 2026
Security Snapshot
Axsome Therapeutics, Inc. - Common Stock (AXSM) Institutional Ownership
CUSIP: 05464T104
13F Institutional Holders and Ownership History from Q4 2015 to Q1 2026
Institutions Reporting
408
Shares (Excl. Options)
37,911,815
Price
$169.02
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- Security type / class
- Equity / Common Stock
- Symbol
- AXSM on Nasdaq
- All holders as of 31 Mar 2026
- Q1 2026
- Total 13F shares
- 37,911,815
- Total 13F value
- $6,405,262,044
- Portfolio coverage rank
- 0.02%
- Share change
- +230,731
- Value change
- +$6,636,802
- Number of holders
- 408
- Shares outstanding
- 48,932,355
- SEC-reported price per share
- $224.03
- Insider filing price
- $224.03
Latest holder snapshot
5 signals
Issuer context
Names, identifiers, and filing context for this profile.
3 identity fields
13F Shares, Excluding Options vs Price
13F Value, Excluding Options
Total Investors
Key facts
- AXSM - Axsome Therapeutics, Inc. - Common Stock is tracked under CUSIP 05464T104.
- 408 institutions reported positions in Q1 2026.
- 1 significant owner is listed from Schedule 13D/13G reporting.
Change
- Holder count moved from 397 to 408 between Q4 2025 and Q1 2026.
- SEC-reported value moved from $6,859,714,741 to $6,405,262,044.
Research use
- You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
- 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.
Evidence
Source: SEC Form 13F
Open SEC evidence
Latest holder context comes from 408 institutions filings for Q1 2026.
Security key
05464T104
Latest holder period
Q1 2026
13F holders
408
13D/G owners
1
CIK / CUSIP context first
Open Q1 2026 holders
AXSM full holder history
Axsome Therapeutics, Inc. SEC filings
Axsome Therapeutics, Inc. company facts
Axsome Therapeutics, Inc. insider transactions
Broader feeds
Recent Quarterly Holder Reports
Open recent reporting periods for CUSIP 05464T104:
13D/G owners
Significant owners
Large-stake holder rows connected to Schedule 13D/G evidence.
Rows
1
Security
AXSM
| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| RTW INVESTMENTS, LP | 3.1% | -48% | $165,312,089 | -$153,206,917 | 1,516,903 | -48% | RTW Investments, LP | 30 Jun 2025 |
As of 31 Mar 2026, 408 institutional investors reported holding 37,911,815 shares of Axsome Therapeutics, Inc. - Common Stock (AXSM). This represents 77% of the company’s total 48,932,355 outstanding shares.
13F concentration
Top 25 institutional shareholders
Largest 13F positions for this security by reported shares and value.
Top holder share
51%
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| BlackRock, Inc. | 8% | 3,912,844 | -0.02% | 0.01% | $661,348,893 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 4.2% | 2,058,170 | 0% | 0.02% | $347,871,893 |
| VANGUARD CAPITAL MANAGEMENT LLC | 4% | 1,937,752 | 0% | 0.01% | $327,518,843 |
| FMR LLC | 3.2% | 1,566,995 | +33% | 0.01% | $264,853,495 |
| PRICE T ROWE ASSOCIATES INC /MD/ | 2.7% | 1,317,059 | -13% | 0.03% | $222,610,000 |
| Invesco Ltd. | 2.7% | 1,297,678 | +1.9% | 0.03% | $219,333,537 |
| GEODE CAPITAL MANAGEMENT, LLC | 2.4% | 1,162,981 | +15% | 0.01% | $196,601,071 |
| WELLINGTON MANAGEMENT GROUP LLP | 2.3% | 1,145,306 | -6.2% | 0.04% | $193,579,622 |
| Deep Track Capital, LP | 2.2% | 1,100,000 | -4.3% | 3.8% | $185,922,000 |
| STATE STREET CORP | 2% | 986,809 | +3% | 0.01% | $166,790,457 |
| Assenagon Asset Management S.A. | 1.8% | 865,958 | +85% | 0.23% | $146,364,221 |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | 1.7% | 812,809 | -18% | 0.24% | $137,381,000 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 1.5% | 737,578 | +101% | 0.19% | $124,665,434 |
| ALETHEA CAPITAL MANAGEMENT, LLC | 1.3% | 649,114 | -2.9% | 59% | $109,713,248 |
| D. E. Shaw & Co., Inc. | 1.2% | 603,465 | +9.9% | 0.08% | $101,997,654 |
| BANK OF AMERICA CORP /DE/ | 1.2% | 598,091 | -3.2% | 0.01% | $101,089,343 |
| FIRST TRUST ADVISORS LP | 1.2% | 577,479 | +1230% | 0.07% | $97,605,500 |
| UBS Group AG | 1.1% | 547,195 | +54% | 0.02% | $92,486,898 |
| EVENTIDE ASSET MANAGEMENT, LLC | 1.1% | 519,558 | -9% | 1.5% | $87,776,957 |
| MORGAN STANLEY | 0.97% | 476,701 | -3% | 0% | $80,572,042 |
| FRANKLIN RESOURCES INC | 0.9% | 438,490 | +28% | 0.02% | $74,113,581 |
| Point72 Asset Management, L.P. | 0.87% | 424,750 | +2260% | 0.12% | $71,791,245 |
| GOLDMAN SACHS GROUP INC | 0.86% | 421,447 | +40% | 0.01% | $71,232,972 |
| Pictet Asset Management Holding SA | 0.85% | 415,983 | -4.6% | 0.07% | $70,306,277 |
| NORTHERN TRUST CORP | 0.82% | 401,459 | +2.8% | 0.01% | $67,854,600 |
Quarter history
Institutional holders across reporting periods
Holder count, reported shares/value, and median price by quarter.
Periods
42
Latest
Q1 2026
Rows shown
1-25 of 42
| Period | 13F Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2026 Q1 | 37,911,815 | $6,405,262,044 | +$6,636,802 | $169.02 | 408 |
| 2025 Q4 | 37,608,361 | $6,859,714,741 | +$12,741,708 | $182.64 | 397 |
| 2025 Q3 | 37,169,613 | $4,513,412,476 | -$67,590,005 | $121.45 | 352 |
| 2025 Q2 | 37,843,872 | $3,950,044,159 | +$74,087,650 | $104.39 | 345 |
| 2025 Q1 | 36,999,749 | $4,315,367,902 | +$55,229,563 | $116.63 | 349 |
| 2024 Q4 | 37,175,235 | $3,145,106,906 | -$176,513,164 | $84.61 | 290 |
| 2024 Q3 | 38,678,079 | $3,475,093,026 | -$190,434,872 | $89.87 | 277 |
| 2024 Q2 | 40,712,369 | $3,277,256,100 | +$165,407,783 | $80.50 | 253 |
| 2024 Q1 | 38,735,398 | $3,089,970,732 | +$16,979,676 | $79.80 | 254 |
| 2023 Q4 | 38,597,370 | $3,071,777,083 | +$30,855,225 | $79.59 | 242 |
| 2023 Q3 | 37,879,928 | $2,647,367,402 | +$88,702,381 | $69.89 | 224 |
| 2023 Q2 | 36,371,724 | $2,613,474,662 | +$329,094,500 | $71.86 | 227 |
| 2023 Q1 | 31,901,760 | $1,967,140,427 | +$94,141,631 | $61.68 | 194 |
| 2022 Q4 | 30,053,540 | $2,317,913,385 | +$384,566,478 | $77.13 | 213 |
| 2022 Q3 | 25,705,114 | $1,146,849,855 | +$196,048,585 | $44.62 | 180 |
| 2022 Q2 | 21,590,557 | $826,608,565 | +$90,967,881 | $38.30 | 164 |
| 2022 Q1 | 19,105,701 | $787,305,601 | +$28,307,048 | $41.39 | 165 |
| 2021 Q4 | 18,632,401 | $703,886,639 | -$18,569,388 | $37.78 | 161 |
| 2021 Q3 | 19,030,753 | $625,717,799 | -$187,658,523 | $32.96 | 165 |
| 2021 Q2 | 22,332,926 | $1,506,651,537 | -$37,805,529 | $67.46 | 172 |
| 2021 Q1 | 22,937,308 | $1,299,681,826 | -$60,738,349 | $56.62 | 181 |
| 2020 Q4 | 23,974,672 | $1,951,921,924 | -$4,134,242 | $81.47 | 178 |
| 2020 Q3 | 24,031,769 | $1,711,934,785 | -$21,143,954 | $71.25 | 171 |
| 2020 Q2 | 24,239,746 | $1,992,911,051 | +$152,460,166 | $82.28 | 188 |
| 2020 Q1 | 22,843,303 | $1,344,655,517 | +$45,174,721 | $58.83 | 163 |