89bio, Inc. - Common stock, par value $0.001 per share (ETNB) Institutional Ownership

13F Institutional Holders and Ownership History from Q4 2019 to Q4 2025

Type / Class
Equity / Common stock, par value $0.001 per share
Symbol
ETNB
Shares outstanding
148,275,293
Price per share
$14.84
All holders as of 30 Sep 2025
Q3 2025
Total 13F shares
154,687,794
Total reported value
$2,273,679,098
% of total 13F portfolios
0.01%
Share change
-6,498,605
Value change
-$595,412
Number of holders
196
Price from insider filings
$14.84
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of 89bio, Inc. - Common stock, par value $0.001 per share (ETNB) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
Deep Track Capital, LP 6.3% -32% $137,535,714 -$65,564,381 9,356,171 -32% Deep Track Capital, LP 30 Sep 2025
SUVRETTA CAPITAL MANAGEMENT, LLC 5.6% -43% $121,716,000 -$93,071,712 8,280,000 -43% SUVRETTA CAPITAL MANAGEMENT, LLC 30 Sep 2025
VANGUARD GROUP INC 5.6% $80,937,952 8,242,154 The Vanguard Group 30 Jun 2025
JANUS HENDERSON GROUP PLC 3.6% -76% $79,060,933 -$226,534,240 5,378,185 -74% JANUS HENDERSON GROUP PLC 30 Sep 2025
BIOTECHNOLOGY VALUE FUND L P 3.6% $29,903,806 4,333,885 BVF PARTNERS L P/IL 31 Dec 2024
RTW INVESTMENTS, LP 1.3% $13,575,936 1,967,527 RTW Investments, LP 31 Mar 2025

As of 30 Sep 2025, 196 institutional investors reported holding 154,687,794 shares of 89bio, Inc. - Common stock, par value $0.001 per share (ETNB). This represents 104% of the company’s total 148,275,293 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of 89bio, Inc. - Common stock, par value $0.001 per share (ETNB) together control 87% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
RA CAPITAL MANAGEMENT, L.P. 13% 19,889,683 0% 3.6% $292,378,340
Pentwater Capital Management LP 7.9% 11,750,000 1.6% $172,725,000
BlackRock, Inc. 7% 10,316,393 -2.4% 0% $151,650,978
Deep Track Capital, LP 6.3% 9,356,171 -1.5% 3.8% $137,535,714
ADAGE CAPITAL PARTNERS GP, L.L.C. 6.1% 9,097,587 +362% 0.21% $133,734,529
SUVRETTA CAPITAL MANAGEMENT, LLC 5.6% 8,280,000 -42% 3.7% $121,716,000
VANGUARD GROUP INC 5.4% 8,053,459 -2.3% 0% $118,385,847
Avoro Capital Advisors LLC 4.3% 6,387,790 -5.4% 1.2% $93,900,513
GLAZER CAPITAL, LLC 3.8% 5,636,905 2.8% $82,863,000
JANUS HENDERSON GROUP PLC 3.6% 5,378,185 -74% 0.04% $79,055,106
STATE STREET CORP 3.6% 5,286,308 +24% 0% $77,708,728
DEUTSCHE BANK AG\ 2.4% 3,499,625 +3942% 0.02% $51,444,487
WESTFIELD CAPITAL MANAGEMENT CO LP 2.2% 3,291,369 -2.4% 0.2% $48,383,124
GEODE CAPITAL MANAGEMENT, LLC 2.1% 3,092,340 -0.61% 0% $45,463,604
SYQUANT CAPITAL SAS 1.7% 2,593,694 11% $38,127,000
KRYGER CAPITAL Ltd 1.6% 2,350,000 4% $34,545,000
TIG Advisors, LLC 1.5% 2,186,648 2% $32,143,726
Hudson Bay Capital Management LP 1.5% 2,172,000 +862% 0.19% $31,928,400
ADAR1 Capital Management, LLC 1.4% 2,113,153 +141% 3.1% $31,063,349
GOLDMAN SACHS GROUP INC 1.1% 1,616,785 +29% 0% $23,766,740
DIMENSIONAL FUND ADVISORS LP 1.1% 1,606,783 +36% 0.01% $23,619,710
Redmile Group, LLC 0.99% 1,473,136 -4.7% 2.1% $21,655,099
Balyasny Asset Management L.P. 0.98% 1,459,055 0.04% $21,448,109
Weiss Asset Management LP 0.94% 1,400,000 0.31% $20,580,000
NORTHERN TRUST CORP 0.76% 1,125,784 -0.59% 0% $16,549,026

Institutional Holders of 89bio, Inc. - Common stock, par value $0.001 per share (ETNB) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 0 $0 -$50,617,620 $14.84 0
2025 Q3 154,687,794 $2,273,679,098 -$595,412 $14.70 196
2025 Q2 161,195,505 $1,583,221,092 +$87,329,463 $9.82 181
2025 Q1 154,244,684 $1,137,978,261 +$235,722,517 $7.27 184
2024 Q4 121,178,976 $947,691,955 +$128,680,752 $7.82 152
2024 Q3 104,404,540 $772,806,478 +$3,735,695 $7.40 142
2024 Q2 103,292,520 $827,294,025 +$24,658,190 $8.01 142
2024 Q1 98,362,601 $1,144,204,045 +$51,039,250 $11.64 147
2023 Q4 94,160,760 $1,051,783,052 +$196,443,321 $11.17 152
2023 Q3 71,959,726 $1,111,096,654 -$104,333,237 $15.44 159
2023 Q2 77,249,037 $1,463,933,277 +$131,611,867 $18.95 157
2023 Q1 70,992,649 $1,081,023,134 +$392,960,831 $15.23 146
2022 Q4 46,306,156 $589,465,858 +$135,450,817 $12.73 106
2022 Q3 39,211,413 $227,032,083 +$45,497,652 $5.79 84
2022 Q2 32,453,686 $104,561,000 +$48,026,442 $3.22 67
2022 Q1 17,066,227 $64,336,000 -$14,898,951 $3.77 65
2021 Q4 17,305,335 $226,115,000 -$710,006 $13.07 48
2021 Q3 17,322,134 $339,441,000 +$9,163,211 $19.59 47
2021 Q2 16,857,498 $315,233,000 -$5,578,791 $18.70 49
2021 Q1 16,916,139 $400,591,000 +$4,523,002 $23.68 67
2020 Q4 16,716,696 $407,455,000 +$14,912,147 $24.37 68
2020 Q3 16,031,339 $411,152,774 +$129,937,788 $25.66 68
2020 Q2 10,412,527 $207,490,000 -$1,581,200 $19.93 36
2020 Q1 10,699,602 $270,165,000 +$7,519,389 $25.25 30
2019 Q4 10,441,990 $274,521,000 +$272,245,001 $26.29 34