Avidity Biosciences, Inc. - Common Stock (RNA) Institutional Ownership

13F Institutional Holders and Ownership History from Q2 2020 to Q4 2025

Type / Class
Equity / Common Stock
Symbol
RNA on Nasdaq
Shares outstanding
150,858,761
Price per share
$72.51
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
140,510,840
Total reported value
$10,134,503,277
% of total 13F portfolios
0.02%
Share change
-20,760,857
Value change
-$697,981,929
Number of holders
334
Price from insider filings
$72.51
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of Avidity Biosciences, Inc. - Common Stock (RNA) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
VANGUARD GROUP INC 9.6% $575,984,900 13,219,759 The Vanguard Group 30 Sep 2025
RA CAPITAL MANAGEMENT, L.P. 5.9% $376,489,721 8,641,031 RA Capital Management, L.P. 30 Sep 2025
BlackRock, Inc. 6.4% -14% $376,086,262 -$17,916,333 8,631,771 -4.5% BlackRock, Inc. 30 Sep 2025
Avoro Capital Advisors LLC 5.5% $614,244,077 8,515,792 Avoro Capital Advisors LLC 31 Dec 2025
JANUS HENDERSON GROUP PLC 4.6% -15% $500,546,351 -$92,717,850 6,939,503 -16% JANUS HENDERSON GROUP PLC 31 Dec 2025
RTW INVESTMENTS, LP 3.1% $204,173,813 4,686,110 RTW Investments, LP 27 Oct 2025
FMR LLC 2.1% -86% $128,911,093 -$809,934,537 2,958,712 -86% FMR LLC 31 Oct 2025
WELLINGTON MANAGEMENT GROUP LLP 0.5% -95% $52,158,501 -$646,388,523 723,118 -93% Wellington Management Group LLP 31 Dec 2025
PRICE T ROWE ASSOCIATES INC /MD/ 0.1% -100% $10,306,511 -$695,695,581 142,888 -99% T. Rowe Price Associates, Inc. 31 Dec 2025

As of 31 Dec 2025, 334 institutional investors reported holding 140,510,840 shares of Avidity Biosciences, Inc. - Common Stock (RNA). This represents 93% of the company’s total 150,858,761 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of Avidity Biosciences, Inc. - Common Stock (RNA) together control 67% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
VANGUARD GROUP INC 9% 13,649,250 +3.2% 0.01% $984,520,403
BlackRock, Inc. 8.5% 12,850,801 +40% 0.02% $926,928,275
RA CAPITAL MANAGEMENT, L.P. 5.7% 8,641,031 0% 6.4% $623,277,566
JANUS HENDERSON GROUP PLC 4.6% 6,939,503 -52% 0.22% $500,560,229
Balyasny Asset Management L.P. 4% 6,040,590 0.82% $435,707,757
Pentwater Capital Management LP 4% 6,026,500 3.1% $434,691,445
Avoro Capital Advisors LLC 3.6% 5,455,000 -29% 3.9% $393,469,150
HBK INVESTMENTS L P 2.9% 4,365,000 3.4% $314,847,450
STATE STREET CORP 2.7% 4,097,885 -16% 0.01% $295,580,445
GOLDMAN SACHS GROUP INC 2.5% 3,776,785 +118% 0.04% $272,419,502
GEODE CAPITAL MANAGEMENT, LLC 2.1% 3,120,780 +9.2% 0.01% $225,144,631
NORGES BANK 2% 3,046,388 0.02% $219,735,966
Bellevue Group AG 1.7% 2,630,969 +22% 3.6% $189,771,794
ADAGE CAPITAL PARTNERS GP, L.L.C. 1.7% 2,630,966 +119% 0.29% $189,771,578
Glazer Capital, LLC 1.6% 2,467,139 4.7% $177,955,000
UBS Group AG 1.6% 2,356,812 +79% 0.03% $169,996,849
MILLENNIUM MANAGEMENT LLC 1.4% 2,157,270 +7182% 0.11% $155,603,885
TIG Advisors, LLC 1.2% 1,801,683 6.3% $129,955,395
CITADEL ADVISORS LLC 1.1% 1,592,429 +77% 0.08% $114,861,904
CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.78% 1,181,661 +5.2% 0.01% $85,233,208
Magnetar Financial LLC 0.77% 1,158,603 0.82% $83,570,034
FIL Ltd 0.76% 1,144,000 0.06% $82,516,720
Qube Research & Technologies Ltd 0.73% 1,105,830 0.11% $79,763,518
MORGAN STANLEY 0.72% 1,092,482 +58% 0% $78,800,809
ALLIANCEBERNSTEIN L.P. 0.69% 1,047,410 +742% 0.02% $75,549,683

Institutional Holders of Avidity Biosciences, Inc. - Common Stock (RNA) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 140,510,840 $10,134,503,277 -$697,981,929 $72.13 334
2025 Q3 160,911,766 $7,009,507,783 +$1,158,007,539 $43.57 269
2025 Q2 135,973,420 $3,861,676,519 +$69,697,401 $28.40 205
2025 Q1 133,409,309 $3,962,056,176 +$178,442,627 $29.52 218
2024 Q4 127,638,993 $3,712,638,686 -$78,035,782 $29.08 234
2024 Q3 126,231,192 $5,796,026,453 +$574,015,774 $45.93 240
2024 Q2 111,913,147 $4,571,667,339 +$938,038,576 $40.85 191
2024 Q1 89,252,994 $2,277,667,387 +$376,305,703 $25.52 156
2023 Q4 75,910,042 $687,025,653 -$46,186,576 $9.05 142
2023 Q3 81,744,893 $521,542,443 -$6,429,051 $6.38 142
2023 Q2 82,383,646 $913,636,020 +$45,839,329 $11.09 140
2023 Q1 75,916,643 $1,165,169,505 +$49,763,836 $15.35 138
2022 Q4 71,661,062 $1,590,188,145 +$426,293,719 $22.19 148
2022 Q3 53,433,471 $872,653,344 -$22,171,694 $16.33 121
2022 Q2 52,143,220 $757,668,637 +$70,638,105 $14.53 107
2022 Q1 47,057,452 $869,011,980 +$27,227,715 $18.47 98
2021 Q4 45,418,262 $1,079,557,657 +$3,680,968 $23.77 104
2021 Q3 44,395,070 $1,093,343,381 +$240,851,131 $24.63 108
2021 Q2 34,505,931 $852,616,782 +$16,849,564 $24.71 93
2021 Q1 33,888,914 $739,147,936 +$60,802,116 $21.81 97
2020 Q4 30,963,803 $790,224,311 +$74,813,975 $25.52 82
2020 Q3 27,022,951 $755,460,115 +$43,834,764 $28.15 67
2020 Q2 25,458,553 $701,864,000 +$701,864,000 $28.26 52