Security Snapshot

Stoke Therapeutics, Inc. - Common Stock, $0.0001 par value per share (STOK) Institutional Ownership

CUSIP: 86150R107

13F Institutional Holders and Ownership History from Q2 2019 to Q1 2026

Latest Period

Q1 2026

Institutions Reporting

196

Shares (Excl. Options)

71,107,852

Price

$32.56

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Type / Class
Equity / Common Stock, $0.0001 par value per share
Symbol
STOK on Nasdaq
Shares outstanding
58,810,778
Price per share
$32.42
All holders as of 31 Mar 2026
Q1 2026
Total 13F shares
71,107,852
Total reported value
$2,314,610,833
% of total 13F portfolios
0.01%
Share change
+3,993,162
Value change
+$131,278,501
Number of holders
196
Price from insider filings
$32.42
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Key facts

  • STOK - Stoke Therapeutics, Inc. - Common Stock, $0.0001 par value per share is tracked under CUSIP 86150R107.
  • 196 institutions reported positions in Q1 2026.
  • 11 significant owners is listed from Schedule 13D/13G reporting.

Change

  • Holder count moved from 183 to 196 between Q4 2025 and Q1 2026.
  • Reported value moved from $2,126,072,755 to $2,314,610,833.

Research use

  • You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
  • 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.

Evidence

Source: SEC Form 13F

Latest holder context comes from 196 institutions filings for Q1 2026.

Open SEC Evidence

Security key

86150R107

Latest holder period

Q1 2026

13F holders

196

13D/G owners

11

CIK / CUSIP context first

Significant Owners of Stoke Therapeutics, Inc. - Common Stock, $0.0001 par value per share (STOK) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
RTW INVESTMENTS, LP 9.9% -0.9% $208,227,353 +$22,110,697 5,940,866 +12% RTW Investments, LP 31 Mar 2026
FMR LLC 9.8% -21% $177,773,201 -$40,123,708 5,600,920 -18% FMR LLC 31 Dec 2025
Lynx1 Capital Management LP 8.1% $154,438,279 4,763,673 Lynx1 Capital Management LP 31 Mar 2026
Redmile Group, LLC 6.7% -16% $145,952,406 -$7,423,976 4,164,120 -4.8% Redmile Group, LLC 31 Mar 2026
BlackRock, Inc. 6.8% +17% $87,769,558 +$14,428,761 3,732,540 +20% BlackRock, Inc. 30 Sep 2025
MORGAN STANLEY 6.5% $32,588,288 3,426,739 Morgan Stanley 31 Dec 2024
BAKER BROS. ADVISORS LP 5.8% $105,906,763 3,336,697 Baker Bros. Advisors LP 31 Dec 2025
TORONTO DOMINION BANK 5.4% -6.7% $111,222,693 3,173,258 0% The Toronto-Dominion Bank 31 Mar 2026
WELLINGTON MANAGEMENT GROUP LLP 5.2% $108,504,285 3,095,700 Wellington Management Group LLP 31 Mar 2026
BlackRock Portfolio Management LLC 4.7% -8% $28,946,115 -$2,192,358 2,550,341 -7% BlackRock Portfolio Management LLC 30 Jun 2025
Skorpios Trust 4.1% -32% $29,037,049 -$12,870,000 2,256,181 -31% Montrago Trustees Ltd 22 Aug 2025

As of 31 Mar 2026, 196 institutional investors reported holding 71,107,852 shares of Stoke Therapeutics, Inc. - Common Stock, $0.0001 par value per share (STOK). This represents 121% of the company’s total 58,810,778 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of Stoke Therapeutics, Inc. - Common Stock, $0.0001 par value per share (STOK) together control 103% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
RTW INVESTMENTS, LP 9.6% 5,623,525 +1.4% 1.8% $183,101,974
BlackRock, Inc. 9.2% 5,385,714 +3.3% 0% $175,358,848
FMR LLC 9.2% 5,383,666 -3.9% 0.01% $175,292,165
Lynx1 Capital Management LP 8.1% 4,763,673 -12% 25% $155,105,193
Redmile Group, LLC 7.1% 4,164,120 +3.2% 9% $135,583,747
MORGAN STANLEY 5.8% 3,423,280 -3.5% 0.01% $111,461,996
BAKER BROS. ADVISORS LP 5.7% 3,336,697 0% 0.62% $108,642,854
TORONTO DOMINION BANK 5.4% 3,173,258 0% 0.2% $103,321,280
WELLINGTON MANAGEMENT GROUP LLP 5.3% 3,095,700 +321% 0.02% $100,795,992
BVF INC/IL 4.3% 2,547,557 +12% 2.6% $82,948,456
VANGUARD CAPITAL MANAGEMENT LLC 4% 2,355,603 0% 0% $76,698,434
STATE STREET CORP 3.9% 2,276,512 -8.9% 0% $74,123,231
Siren, L.L.C. 3.4% 1,995,347 -11% 1.8% $64,968,498
PRICE T ROWE ASSOCIATES INC /MD/ 3.3% 1,934,171 +419% 0.01% $62,977,000
DEERFIELD MANAGEMENT COMPANY, L.P. 3.1% 1,823,500 0% 0.7% $59,373,160
JANUS HENDERSON GROUP PLC 2.7% 1,612,781 +11% 0.03% $52,455,703
GEODE CAPITAL MANAGEMENT, LLC 2.2% 1,322,260 +13% 0% $43,060,709
Polar Capital Holdings Plc 1.9% 1,132,511 -11% 0.16% $36,874,558
DIMENSIONAL FUND ADVISORS LP 1.7% 989,936 +20% 0.01% $32,228,581
Assenagon Asset Management S.A. 1.5% 907,015 -26% 0.05% $29,532,408
GOLDMAN SACHS GROUP INC 1.4% 830,702 -27% 0% $27,047,658
MPM BIOIMPACT LLC 1.3% 767,038 -0.42% 1.9% $24,974,757
Opaleye Management Inc. 1.2% 700,000 +0.72% 3.2% $22,792,000
Troluce Capital Advisors LLC 1.1% 652,800 2.2% $21,255,168
BAILLIE GIFFORD & CO 0.98% 575,182 +133% 0.02% $18,727,927

Institutional Holders of Stoke Therapeutics, Inc. - Common Stock, $0.0001 par value per share (STOK) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2026 Q1 71,107,852 $2,314,610,833 +$131,278,501 $32.56 196
2025 Q4 66,984,195 $2,126,072,755 +$58,211,085 $31.74 183
2025 Q3 67,691,438 $1,574,062,054 +$64,324,837 $23.50 151
2025 Q2 65,548,147 $743,993,162 +$30,166,679 $11.35 133
2025 Q1 63,384,229 $421,575,155 +$30,343,505 $6.65 124
2024 Q4 58,062,255 $640,428,361 -$5,638,079 $11.03 129
2024 Q3 58,214,468 $715,466,637 -$45,762,031 $12.29 116
2024 Q2 61,301,002 $828,175,296 +$96,412,204 $13.51 114
2024 Q1 54,138,461 $730,867,238 +$123,726,512 $13.50 101
2023 Q4 45,032,645 $236,869,874 +$6,784,370 $5.26 81
2023 Q3 43,943,299 $173,133,829 -$18,481,683 $3.94 96
2023 Q2 46,534,137 $494,657,865 +$21,008,744 $10.63 98
2023 Q1 44,636,031 $371,816,808 +$35,289,257 $8.33 97
2022 Q4 40,284,847 $371,831,189 -$22,554,117 $9.23 106
2022 Q3 42,272,703 $544,351,939 -$11,748,534 $12.84 99
2022 Q2 43,072,954 $569,403,611 +$19,595,358 $13.21 88
2022 Q1 41,334,322 $870,301,369 +$123,934,287 $21.05 96
2021 Q4 35,383,061 $848,561,802 +$26,332,046 $23.99 91
2021 Q3 19,355,184 $492,398,465 -$30,803,526 $25.44 89
2021 Q2 20,216,239 $680,314,450 -$703,085,149 $33.66 96
2021 Q1 38,422,385 $1,492,282,987 -$15,747,693 $38.84 104
2020 Q4 38,644,696 $2,393,196,414 +$252,468,837 $61.93 93
2020 Q3 34,632,372 $1,159,842,494 +$2,937,942 $33.49 89
2020 Q2 34,945,268 $824,517,432 +$9,797,711 $23.83 70
2020 Q1 34,562,212 $791,472,895 +$23,374,012 $22.90 67
2019 Q4 33,483,529 $948,191,901 +$22,388,802 $28.32 64
2019 Q3 15,935,472 $338,961,585 +$30,078,348 $21.49 52
2019 Q2 14,232,528 $409,341,450 +$409,341,450 $29.17 47
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