Latest Period
Q4 2025
Security Snapshot
Stoke Therapeutics, Inc. - Common Stock (STOK) Institutional Ownership
CUSIP: 86150R107
13F Institutional Holders and Ownership History from Q2 2019 to Q1 2026
Institutions Reporting
181
Shares (Excl. Options)
66,978,965
Price
$31.74
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- Type / Class
- Equity / Common Stock
- Symbol
- STOK on Nasdaq
- Shares outstanding
- 57,529,259
- Price per share
- $35.05
- All holders as of 31 Dec 2025
- Q4 2025
- Total 13F shares
- 66,978,965
- Total reported value
- $2,125,906,975
- % of total 13F portfolios
- 0%
- Share change
- +1,536,191
- Value change
- +$58,211,085
- Number of holders
- 181
- Price from insider filings
- $35.05
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors
Quick Takeaways
- STOK - Stoke Therapeutics, Inc. - Common Stock is tracked under CUSIP 86150R107.
- 181 institutions reported positions in Q4 2025.
- 9 significant owners is listed from Schedule 13D/13G reporting.
What Changed
- Holder count moved from 181 to 35 between Q4 2025 and Q1 2026.
- Reported value moved from $2,125,906,975 to $57,526,480.
Why This Matters
- You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
- 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.
Source Evidence
Source: SEC Form 13F
Open SEC Evidence
Latest holder context comes from 181 institutions filings for Q4 2025.
Investment Quick Answers
What is CUSIP 86150R107?
CUSIP 86150R107 identifies STOK - Stoke Therapeutics, Inc. - Common Stock in SEC 13F datasets.
Where can I see the latest institutional holders?
Review the Q4 2025 holders report and the ownership history table below.
Next ownership checks
Use the next link that matches the question you still need to answer about this security.
- Latest 13F filings when you want to inspect fresh institutional portfolio moves.
- Latest Schedule 13D/13G reports when you need large-owner changes outside the 13F cycle.
- All institutional ownership pages to compare this security with other holder-history pages.
Recent Quarterly Holder Reports
Open recent reporting periods for CUSIP 86150R107:
Significant Owners of Stoke Therapeutics, Inc. - Common Stock (STOK) based on Schedule 13D/G filings
| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| FMR LLC | 9.8% | -21% | $177,773,201 | -$40,123,708 | 5,600,920 | -18% | FMR LLC | 31 Dec 2025 |
| RTW INVESTMENTS, LP | 10% | $50,498,414 | 5,310,033 | RTW Investments, LP | 31 Dec 2024 | |||
| Redmile Group, LLC | 8% | $52,554,931 | 4,375,931 | Redmile Group, LLC | 30 Jun 2025 | |||
| BlackRock, Inc. | 6.8% | +17% | $87,769,558 | +$14,428,761 | 3,732,540 | +20% | BlackRock, Inc. | 30 Sep 2025 |
| MORGAN STANLEY | 6.5% | $32,588,288 | 3,426,739 | Morgan Stanley | 31 Dec 2024 | |||
| BAKER BROS. ADVISORS LP | 5.8% | $105,906,763 | 3,336,697 | Baker Bros. Advisors LP | 31 Dec 2025 | |||
| TORONTO DOMINION BANK | 5.8% | $74,571,563 | 3,173,258 | The Toronto-Dominion Bank | 30 Sep 2025 | |||
| BlackRock Portfolio Management LLC | 4.7% | -8% | $28,946,115 | -$2,192,358 | 2,550,341 | -7% | BlackRock Portfolio Management LLC | 30 Jun 2025 |
| Skorpios Trust | 4.1% | -32% | $29,037,049 | -$12,870,000 | 2,256,181 | -31% | Montrago Trustees Ltd | 22 Aug 2025 |
As of 31 Dec 2025, 181 institutional investors reported holding 66,978,965 shares of Stoke Therapeutics, Inc. - Common Stock (STOK). This represents 116% of the company’s total 57,529,259 outstanding shares.
Top 25 Institutional Shareholders
The largest institutional shareholders of Stoke Therapeutics, Inc. - Common Stock (STOK) together control 103% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| FMR LLC | 9.7% | 5,600,920 | -18% | 0.01% | $177,773,201 |
| RTW INVESTMENTS, LP | 9.6% | 5,546,856 | +8.3% | 1.8% | $176,057,209 |
| Lynx1 Capital Management LP | 9.4% | 5,404,674 | 0% | 35% | $171,544,353 |
| BlackRock, Inc. | 9.1% | 5,212,554 | -13% | 0% | $165,446,463 |
| Redmile Group, LLC | 7% | 4,034,070 | -3.4% | 9.4% | $128,041,382 |
| MORGAN STANLEY | 6.2% | 3,546,158 | +0.26% | 0.01% | $112,555,054 |
| BAKER BROS. ADVISORS LP | 5.8% | 3,336,697 | -28% | 0.62% | $105,906,763 |
| TORONTO DOMINION BANK | 5.5% | 3,173,258 | 0% | 0.18% | $100,719,209 |
| VANGUARD GROUP INC | 5.5% | 3,149,239 | -0.46% | 0% | $99,956,846 |
| STATE STREET CORP | 4.3% | 2,498,049 | +75% | 0% | $79,288,075 |
| BVF INC/IL | 3.9% | 2,265,674 | +37% | 2.4% | $71,912,493 |
| Siren, L.L.C. | 3.9% | 2,247,347 | 0% | 2.1% | $71,330,794 |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 3.2% | 1,823,500 | 0.74% | $57,877,890 | |
| JANUS HENDERSON GROUP PLC | 2.5% | 1,450,933 | +334% | 0.02% | $46,031,447 |
| Polar Capital Holdings Plc | 2.2% | 1,269,131 | -4.1% | 0.18% | $40,282,218 |
| Assenagon Asset Management S.A. | 2.1% | 1,227,723 | +36% | 0.06% | $38,967,928 |
| Point72 Asset Management, L.P. | 2.1% | 1,222,213 | -6.5% | 0.06% | $38,793,041 |
| GEODE CAPITAL MANAGEMENT, LLC | 2% | 1,166,145 | +1.7% | 0% | $37,019,868 |
| GOLDMAN SACHS GROUP INC | 2% | 1,142,737 | -0.71% | 0.01% | $36,270,472 |
| DIMENSIONAL FUND ADVISORS LP | 1.4% | 827,139 | +22% | 0.01% | $26,253,770 |
| MPM BIOIMPACT LLC | 1.3% | 770,289 | -2.5% | 2.8% | $24,448,973 |
| WELLINGTON MANAGEMENT GROUP LLP | 1.3% | 735,799 | -0.26% | 0% | $23,354,261 |
| Opaleye Management Inc. | 1.2% | 695,000 | +1.9% | 2.9% | $22,059,300 |
| TANG CAPITAL MANAGEMENT LLC | 0.87% | 500,000 | 0% | 0.78% | $15,870,000 |
| Candriam S.C.A. | 0.78% | 446,690 | 0.07% | $14,178,544 |
Institutional Holders of Stoke Therapeutics, Inc. - Common Stock (STOK) across Reporting Periods
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2026 Q1 | 1,766,250 | $57,526,480 | -$5,989,634 | $32.56 | 35 |
| 2025 Q4 | 66,978,965 | $2,125,906,975 | +$58,211,085 | $31.74 | 181 |
| 2025 Q3 | 67,691,438 | $1,574,062,054 | +$64,324,837 | $23.50 | 151 |
| 2025 Q2 | 65,548,147 | $743,993,162 | +$30,166,679 | $11.35 | 133 |
| 2025 Q1 | 63,384,229 | $421,575,155 | +$30,343,505 | $6.65 | 124 |
| 2024 Q4 | 58,062,255 | $640,428,361 | -$5,638,079 | $11.03 | 129 |
| 2024 Q3 | 58,214,468 | $715,466,637 | -$45,762,031 | $12.29 | 116 |
| 2024 Q2 | 61,301,002 | $828,175,296 | +$96,412,204 | $13.51 | 114 |
| 2024 Q1 | 54,138,461 | $730,867,238 | +$123,726,512 | $13.50 | 101 |
| 2023 Q4 | 45,032,645 | $236,869,874 | +$6,784,370 | $5.26 | 81 |
| 2023 Q3 | 43,943,299 | $173,133,829 | -$18,481,683 | $3.94 | 96 |
| 2023 Q2 | 46,534,137 | $494,657,865 | +$21,008,744 | $10.63 | 98 |
| 2023 Q1 | 44,636,031 | $371,816,808 | +$35,289,257 | $8.33 | 97 |
| 2022 Q4 | 40,284,847 | $371,831,189 | -$22,554,117 | $9.23 | 106 |
| 2022 Q3 | 42,272,703 | $544,351,939 | -$11,748,534 | $12.84 | 99 |
| 2022 Q2 | 43,072,954 | $569,403,611 | +$19,595,358 | $13.21 | 88 |
| 2022 Q1 | 41,334,322 | $870,301,369 | +$123,934,287 | $21.05 | 96 |
| 2021 Q4 | 35,383,061 | $848,561,802 | +$26,332,046 | $23.99 | 91 |
| 2021 Q3 | 19,355,184 | $492,398,465 | -$30,803,526 | $25.44 | 89 |
| 2021 Q2 | 20,216,239 | $680,314,450 | -$703,085,149 | $33.66 | 96 |
| 2021 Q1 | 38,422,385 | $1,492,282,987 | -$15,747,693 | $38.84 | 104 |
| 2020 Q4 | 38,644,696 | $2,393,196,414 | +$252,468,837 | $61.93 | 93 |
| 2020 Q3 | 34,632,372 | $1,159,842,494 | +$2,937,942 | $33.49 | 89 |
| 2020 Q2 | 34,945,268 | $824,517,432 | +$9,797,711 | $23.83 | 70 |
| 2020 Q1 | 34,562,212 | $791,472,895 | +$23,374,012 | $22.90 | 67 |
| 2019 Q4 | 33,483,529 | $948,191,901 | +$22,388,802 | $28.32 | 64 |
| 2019 Q3 | 15,935,472 | $338,961,585 | +$30,078,348 | $21.49 | 52 |
| 2019 Q2 | 14,232,528 | $409,341,450 | +$409,341,450 | $29.17 | 47 |