| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| BlackRock, Inc. | 11.9% | $292,813,929 | 19,878,746 | BlackRock, Inc. | 31 Jan 2025 | |||
| RTW INVESTMENTS, LP | 4.2% | -20% | $152,464,142 | -$33,311,249 | 7,144,524 | -18% | RTW Investments, LP | 30 Sep 2025 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price | Investors |
|---|---|---|---|---|---|
| 2025 Q3 | 167,652,719 | $3,576,525,165 | -$46,292,455 | $21.34 | 326 |
| 2025 Q2 | 169,807,590 | $3,663,065,967 | -$28,402,837 | $21.57 | 308 |
| 2025 Q1 | 171,490,817 | $2,848,881,391 | +$139,123,298 | $16.61 | 315 |
| 2024 Q4 | 162,840,883 | $2,987,247,881 | +$134,856,202 | $18.35 | 292 |
| 2024 Q3 | 155,896,219 | $2,398,194,293 | -$102,074,875 | $15.38 | 257 |
| 2024 Q2 | 161,184,775 | $2,619,212,148 | -$8,478,472 | $16.25 | 265 |
| 2024 Q1 | 161,305,797 | $2,982,051,495 | -$11,656,862 | $18.49 | 266 |
| 2023 Q4 | 159,519,491 | $4,994,576,405 | +$146,161,056 | $31.31 | 272 |
| 2023 Q3 | 156,109,164 | $3,253,545,379 | -$82,496,501 | $20.84 | 246 |
| 2023 Q2 | 159,054,444 | $3,809,481,545 | +$45,597,747 | $23.95 | 232 |
| 2023 Q1 | 158,037,917 | $2,974,292,426 | +$53,351,193 | $18.82 | 231 |
| 2022 Q4 | 155,962,184 | $2,482,889,933 | +$28,684,244 | $15.92 | 221 |
| 2022 Q3 | 152,629,101 | $2,497,282,084 | +$30,373,584 | $16.36 | 213 |
| 2022 Q2 | 150,587,330 | $2,121,823,126 | +$730,128 | $14.09 | 229 |
| 2022 Q1 | 147,043,761 | $3,562,570,671 | -$19,931,550 | $24.22 | 254 |
| 2021 Q4 | 148,180,956 | $3,457,975,885 | +$79,727,176 | $23.34 | 238 |
| 2021 Q3 | 144,785,492 | $2,405,101,667 | -$85,712,883 | $16.61 | 221 |
| 2021 Q2 | 148,041,851 | $3,610,234,111 | +$54,424,511 | $24.39 | 238 |
| 2021 Q1 | 145,061,195 | $3,742,096,150 | -$221,828,762 | $25.8 | 258 |
| 2020 Q4 | 147,844,682 | $7,903,754,877 | -$103,617,443 | $53.46 | 298 |
| 2020 Q3 | 150,041,187 | $6,188,429,775 | -$100,187,840 | $41.25 | 262 |
| 2020 Q2 | 152,670,605 | $7,396,593,388 | -$42,512,386 | $48.47 | 292 |
| 2020 Q1 | 153,864,301 | $6,498,311,210 | +$189,756,698 | $42.25 | 243 |
| 2019 Q4 | 149,336,660 | $6,388,574,478 | +$119,463,838 | $42.78 | 271 |
| 2019 Q3 | 146,311,376 | $5,266,836,210 | +$305,519,803 | $35.99 | 230 |
| 2019 Q2 | 138,214,602 | $3,694,065,190 | +$147,260,802 | $26.73 | 195 |
| 2019 Q1 | 137,820,078 | $3,700,427,361 | -$451,990 | $26.85 | 197 |
| 2018 Q4 | 139,179,591 | $2,250,311,406 | +$303,421,206 | $16.17 | 174 |
| 2018 Q3 | 119,874,855 | $2,488,872,088 | +$110,894,846 | $20.76 | 179 |
| 2018 Q2 | 116,880,774 | $1,784,764,158 | -$138,301,487 | $15.27 | 179 |
| 2018 Q1 | 122,155,744 | $2,744,894,235 | +$37,280,386 | $22.47 | 190 |
| 2017 Q4 | 120,025,542 | $3,614,245,070 | +$37,065,407 | $30.11 | 208 |
| 2017 Q3 | 117,812,246 | $4,438,878,279 | -$56,072,336 | $37.67 | 207 |
| 2017 Q2 | 119,784,893 | $3,339,520,564 | +$82,800,071 | $27.89 | 199 |
| 2017 Q1 | 119,547,665 | $4,109,936,889 | +$169,511,200 | $34.38 | 215 |
| 2016 Q4 | 121,076,367 | $3,491,800,173 | +$84,990,989 | $28.84 | 217 |
| 2016 Q3 | 117,841,646 | $3,747,670,757 | +$216,713,692 | $31.81 | 226 |
| 2016 Q2 | 111,052,551 | $3,607,314,539 | +$14,491,210 | $32.46 | 223 |
| 2016 Q1 | 110,397,760 | $3,086,115,226 | +$351,841,425 | $27.96 | 210 |
| 2015 Q4 | 97,471,495 | $3,474,862,840 | -$45,955,147 | $35.65 | 209 |
| 2015 Q3 | 98,550,415 | $3,258,991,567 | +$13,497,283 | $33.07 | 184 |
| 2015 Q2 | 98,249,994 | $4,115,830,564 | +$65,989,817 | $41.88 | 187 |
| 2015 Q1 | 97,313,733 | $3,171,615,843 | +$38,284,508 | $32.59 | 193 |
| 2014 Q4 | 96,269,604 | $3,056,562,395 | +$57,829,247 | $31.75 | 182 |
| 2014 Q3 | 94,226,006 | $2,333,141,119 | -$12,371,945 | $24.76 | 162 |
| 2014 Q2 | 95,058,715 | $2,147,349,372 | +$59,674,967 | $22.59 | 160 |
| 2014 Q1 | 90,910,051 | $2,211,056,887 | +$189,059,322 | $24.33 | 164 |