Latest Period
Q4 2025
Security Snapshot
uniQure N.V. - COMMON STOCK (QURE) Institutional Ownership
CUSIP: N90064101
13F Institutional Holders and Ownership History from Q1 2014 to Q1 2026
Institutions Reporting
221
Shares (Excl. Options)
61,851,441
Price
$23.93
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- Type / Class
- Equity / COMMON STOCK
- Symbol
- QURE on Nasdaq
- Shares outstanding
- 62,278,853
- Price per share
- $17.92
- All holders as of 31 Dec 2025
- Q4 2025
- Total 13F shares
- 61,851,441
- Total reported value
- $1,480,095,997
- % of total 13F portfolios
- 0.01%
- Share change
- +6,308,290
- Value change
- -$115,090,755
- Number of holders
- 221
- Price from insider filings
- $17.92
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors
Quick Takeaways
- QURE - uniQure N.V. - COMMON STOCK is tracked under CUSIP N90064101.
- 221 institutions reported positions in Q4 2025.
- 8 significant owners is listed from Schedule 13D/13G reporting.
What Changed
- Holder count moved from 221 to 54 between Q4 2025 and Q1 2026.
- Reported value moved from $1,480,095,997 to $152,193,823.
Why This Matters
- You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
- 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.
Source Evidence
Source: SEC Form 13F
Open SEC Evidence
Latest holder context comes from 221 institutions filings for Q4 2025.
Investment Quick Answers
What is CUSIP N90064101?
CUSIP N90064101 identifies QURE - uniQure N.V. - COMMON STOCK in SEC 13F datasets.
Where can I see the latest institutional holders?
Review the Q4 2025 holders report and the ownership history table below.
Next ownership checks
Use the next link that matches the question you still need to answer about this security.
- Latest 13F filings when you want to inspect fresh institutional portfolio moves.
- Latest Schedule 13D/13G reports when you need large-owner changes outside the 13F cycle.
- All institutional ownership pages to compare this security with other holder-history pages.
Recent Quarterly Holder Reports
Open recent reporting periods for CUSIP N90064101:
Significant Owners of uniQure N.V. - COMMON STOCK (QURE) based on Schedule 13D/G filings
| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| Avoro Capital Advisors LLC | 9.9% | +47% | $143,848,500 | +$59,059,750 | 6,150,000 | +70% | Avoro Capital Advisors LLC | 31 Dec 2025 |
| Aberdeen Group plc | 8.5% | +43% | $86,759,411 | +$26,613,647 | 5,306,386 | +44% | abrdn Inc. | 01 Apr 2026 |
| RTW INVESTMENTS, LP | 6% | -17% | $86,811,096 | -$16,688,905 | 3,711,462 | -16% | RTW Investments, LP | 31 Dec 2025 |
| SUSQUEHANNA SECURITIES, LLC | 5.7% | $82,718,384 | 3,536,485 | G1 Execution Services, LLC | 31 Dec 2025 | |||
| STATE STREET CORP | 5.2% | $75,574,096 | 3,231,043 | STATE STREET CORPORATION | 31 Dec 2025 | |||
| Nantahala Capital Management, LLC | 3.8% | -40% | $29,546,669 | -$13,394,318 | 2,051,852 | -31% | Nantahala Capital Management, LLC | 30 Jun 2025 |
| FMR LLC | 2.8% | -70% | $31,249,037 | -$77,338,527 | 1,743,808 | -71% | FMR LLC | 31 Mar 2026 |
| Vestal Point Capital, LP | 0.4% | -91% | $13,133,250 | -$202,835,750 | 225,000 | -94% | Vestal Point Capital, LP | 30 Sep 2025 |
As of 31 Dec 2025, 221 institutional investors reported holding 61,851,441 shares of uniQure N.V. - COMMON STOCK (QURE). This represents 99% of the company’s total 62,278,853 outstanding shares.
Top 25 Institutional Shareholders
The largest institutional shareholders of uniQure N.V. - COMMON STOCK (QURE) together control 73% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| FMR LLC | 10% | 6,240,936 | +3% | 0.01% | $149,345,604 |
| Avoro Capital Advisors LLC | 9.9% | 6,150,000 | +38% | 1.4% | $147,169,500 |
| RTW INVESTMENTS, LP | 6% | 3,711,462 | -16% | 0.89% | $88,815,286 |
| Aberdeen Group plc | 5.9% | 3,678,640 | +25% | 0.14% | $88,029,855 |
| STATE STREET CORP | 5.2% | 3,231,043 | +124% | 0% | $77,318,859 |
| JPMORGAN CHASE & CO | 4.7% | 2,934,626 | +155% | 0% | $70,225,603 |
| BlackRock, Inc. | 3.2% | 1,974,988 | +37% | 0% | $47,261,464 |
| TWO SIGMA INVESTMENTS, LP | 2.3% | 1,451,284 | +62% | 0.05% | $34,729,226 |
| MPM BIOIMPACT LLC | 2.2% | 1,381,628 | 3.8% | $33,062,358 | |
| JENNISON ASSOCIATES LLC | 2.2% | 1,371,190 | +37% | 0.02% | $32,812,576 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 2% | 1,218,350 | +440% | 0.04% | $29,155,116 |
| SUVRETTA CAPITAL MANAGEMENT, LLC | 2% | 1,216,734 | 0.73% | $29,116,445 | |
| GOLDMAN SACHS GROUP INC | 1.9% | 1,167,608 | +76% | 0% | $27,940,859 |
| TWO SIGMA ADVISERS, LP | 1.8% | 1,110,400 | +171% | 0.05% | $26,571,872 |
| VANGUARD GROUP INC | 1.7% | 1,051,379 | -6.6% | 0% | $25,159,500 |
| Artia Global Partners LP | 1.6% | 1,023,539 | +55% | 3.9% | $24,493,288 |
| Integral Health Asset Management, LLC | 1.4% | 900,000 | +50% | 1.1% | $21,537,000 |
| MILLENNIUM MANAGEMENT LLC | 1.3% | 803,605 | +319% | 0.01% | $19,230,268 |
| GEODE CAPITAL MANAGEMENT, LLC | 1.2% | 776,071 | +7.5% | 0% | $18,578,179 |
| Fiera Capital Corp | 1.2% | 768,510 | 0.06% | $18,390,444 | |
| FRANKLIN RESOURCES INC | 1.2% | 746,602 | -62% | 0% | $17,866,186 |
| ORBIMED ADVISORS LLC | 1.2% | 737,400 | +61% | 0.38% | $17,645,982 |
| MORGAN STANLEY | 1.2% | 716,927 | +123% | 0% | $17,156,063 |
| Nantahala Capital Management, LLC | 1.1% | 699,298 | -31% | 1% | $16,734,201 |
| Logos Global Management LP | 1.1% | 675,000 | +125% | 1.1% | $16,152,750 |
Institutional Holders of uniQure N.V. - COMMON STOCK (QURE) across Reporting Periods
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2026 Q1 | 9,308,518 | $152,193,823 | +$32,505,726 | $16.35 | 54 |
| 2025 Q4 | 61,851,441 | $1,480,095,997 | -$115,090,755 | $23.93 | 221 |
| 2025 Q3 | 55,352,343 | $3,231,367,488 | +$237,515,957 | $58.37 | 218 |
| 2025 Q2 | 52,961,222 | $738,302,097 | +$50,637,556 | $13.94 | 143 |
| 2025 Q1 | 49,986,625 | $532,054,267 | +$84,767,075 | $10.60 | 139 |
| 2024 Q4 | 41,605,808 | $734,372,507 | +$59,578,946 | $17.66 | 136 |
| 2024 Q3 | 38,874,270 | $192,931,529 | +$40,181,251 | $4.93 | 129 |
| 2024 Q2 | 31,728,639 | $141,844,153 | -$3,825,259 | $4.48 | 112 |
| 2024 Q1 | 32,322,300 | $168,079,173 | -$35,691,371 | $5.20 | 130 |
| 2023 Q4 | 37,687,636 | $255,220,282 | -$8,276,086 | $6.77 | 143 |
| 2023 Q3 | 35,800,237 | $240,082,030 | -$11,389,007 | $6.71 | 160 |
| 2023 Q2 | 35,929,422 | $411,603,802 | -$102,920,571 | $11.46 | 173 |
| 2023 Q1 | 41,579,108 | $837,317,405 | +$27,836,492 | $20.14 | 170 |
| 2022 Q4 | 40,238,914 | $912,094,750 | -$33,364,677 | $22.67 | 174 |
| 2022 Q3 | 42,072,015 | $789,027,381 | +$16,257,084 | $18.76 | 155 |
| 2022 Q2 | 40,495,580 | $754,734,025 | +$52,181,297 | $18.64 | 161 |
| 2022 Q1 | 37,951,511 | $685,692,734 | +$3,739,840 | $18.07 | 162 |
| 2021 Q4 | 37,700,468 | $782,152,012 | -$10,555,469 | $20.74 | 169 |
| 2021 Q3 | 37,029,922 | $1,185,365,197 | +$36,464,815 | $32.01 | 170 |
| 2021 Q2 | 35,921,387 | $1,106,406,897 | -$14,666,760 | $30.80 | 153 |
| 2021 Q1 | 36,324,502 | $1,223,768,350 | +$31,780,970 | $33.69 | 153 |
| 2020 Q4 | 34,974,972 | $1,263,910,909 | -$11,650,805 | $36.13 | 160 |
| 2020 Q3 | 35,272,720 | $1,298,543,100 | -$827,360 | $36.83 | 157 |
| 2020 Q2 | 34,963,826 | $1,573,348,794 | -$20,279,224 | $45.06 | 172 |
| 2020 Q1 | 35,310,616 | $1,675,810,163 | -$22,488,569 | $47.45 | 167 |
| 2019 Q4 | 34,655,343 | $2,483,224,906 | +$183,794,307 | $71.66 | 179 |
| 2019 Q3 | 32,038,308 | $1,260,902,231 | +$155,277,735 | $39.36 | 155 |
| 2019 Q2 | 26,449,920 | $2,066,161,619 | +$440,721,480 | $78.15 | 143 |
| 2019 Q1 | 22,704,127 | $1,354,292,705 | +$7,107,528 | $59.65 | 128 |
| 2018 Q4 | 22,760,640 | $655,512,079 | -$4,279,771 | $28.82 | 93 |
| 2018 Q3 | 22,572,035 | $821,994,896 | +$5,790,048 | $36.39 | 98 |
| 2018 Q2 | 22,030,252 | $832,692,000 | +$220,229,387 | $37.80 | 94 |
| 2018 Q1 | 16,267,232 | $382,280,000 | +$66,881,880 | $23.50 | 66 |
| 2017 Q4 | 13,549,875 | $265,453,073 | +$106,494,269 | $19.59 | 60 |
| 2017 Q3 | 7,666,082 | $73,561,120 | +$258,592 | $9.60 | 35 |
| 2017 Q2 | 7,650,235 | $47,354,000 | +$3,032,085 | $6.19 | 31 |
| 2017 Q1 | 7,213,970 | $41,691,000 | -$1,974,062 | $5.78 | 37 |
| 2016 Q4 | 7,619,508 | $42,662,000 | -$3,166,022 | $5.60 | 50 |
| 2016 Q3 | 7,075,534 | $54,129,000 | -$8,015,435 | $7.65 | 48 |
| 2016 Q2 | 8,137,564 | $59,960,000 | -$8,779,594 | $7.37 | 57 |
| 2016 Q1 | 9,135,928 | $108,531,000 | +$7,848,398 | $11.88 | 56 |
| 2015 Q4 | 8,219,077 | $135,936,000 | -$884,886 | $16.54 | 64 |
| 2015 Q3 | 7,929,168 | $162,145,000 | -$249,360 | $20.45 | 62 |
| 2015 Q2 | 7,678,180 | $207,309,000 | +$75,445,120 | $27.00 | 53 |
| 2015 Q1 | 4,924,505 | $119,703,000 | +$32,132,767 | $24.32 | 40 |
| 2014 Q4 | 3,821,918 | $56,602,200 | +$6,865,008 | $14.81 | 27 |
| 2014 Q3 | 3,456,020 | $31,869,000 | -$65,722 | $9.24 | 26 |
| 2014 Q2 | 3,422,576 | $46,512,000 | +$44,407 | $13.59 | 26 |
| 2014 Q1 | 3,341,209 | $51,981,000 | +$51,981,000 | $15.55 | 24 |