uniQure N.V. - Ordinary Shares, par value 0.05 euro per share (QURE)

Historical Holders from Q1 2014 to Q3 2025

Symbol: QURE on Nasdaq
Type / Class: Equity / Ordinary Shares, par value 0.05 euro per share
Shares outstanding: 61,457,889
All holders as of 30 Sep 2025: Q3 2025
Total 13F shares, excl. options: 55,358,430
Holdings value: $3,231,722,786
% of all portfolios: 0.01%
Number of holders: 219
Number of buys: 144
Number of sells: -81
Average buys %: +0.01%
Average sells %: -0%

Reported Shares, Excluding Options vs Price

Reported Value, Excluding Options

Total Investors

Significant Owners of uniQure N.V. - Ordinary Shares, par value 0.05 euro per share (QURE)

Filer	Ownership	Change %	Holdings Value	Net Change	Nb Shares	Change %	Reporting Name	Report Period
FMR LLC	9.8%		$353,697,322		6,059,573		FMR LLC	30 Sep 2025
RTW INVESTMENTS, LP	7.2%	-24%	$258,285,382	-$42,800,561	4,424,968	-14%	RTW Investments, LP	30 Sep 2025
EcoR1 Capital, LLC	7.5%		$51,793,561		3,632,087		EcoR1 Capital, LLC	10 Dec 2024
Avoro Capital Advisors LLC	6.6%		$52,200,000		3,625,000		Avoro Capital Advisors LLC	30 Jun 2025
Aberdeen Group plc	4.77%	-5%	$171,592,799	+$11,033,623	2,939,743	+6.9%	Aberdeen Group plc	30 Sep 2025
Nantahala Capital Management, LLC	3.75%	-40%	$29,546,669	-$13,394,318	2,051,852	-31%	Nantahala Capital Management, LLC	30 Jun 2025
Vestal Point Capital, LP	0.4%	-91%	$13,133,250	-$202,835,750	225,000	-94%	Vestal Point Capital, LP	30 Sep 2025

Institutional Holders of uniQure N.V. - Ordinary Shares, par value 0.05 euro per share (QURE)

Period	Reported Shares, Excl. Options	Value, Excl. Options	Value Change	Puts Notional Value	Calls Notional Value	Price	Investors
2025 Q3	55,358,430	$3,231,722,786	+$237,871,255	$231,706,629	$221,135,859	$58.37	219
2025 Q2	52,961,222	$738,302,097	+$50,637,556	$17,113,956	$58,468,510	$13.94	143
2025 Q1	49,986,625	$532,054,267	+$84,767,075	$4,602,520	$20,401,672	$10.6	139
2024 Q4	41,605,808	$734,372,507	+$59,578,946	$9,468,580	$41,283,182	$17.66	136
2024 Q3	38,874,270	$192,931,529	+$40,181,251	$2,815,030	$3,811,693	$4.93	129
2024 Q2	31,728,639	$141,844,153	-$3,825,259	$1,538,432	$5,874,624	$4.48	112
2024 Q1	32,322,300	$168,079,173	-$35,691,371	$2,898,480	$4,756,960	$5.2	130
2023 Q4	37,687,636	$255,220,282	-$8,276,086	$2,043,186	$6,225,692	$6.77	143
2023 Q3	35,800,237	$240,082,030	-$11,389,007	$2,137,806	$4,150,806	$6.71	160
2023 Q2	35,929,422	$411,603,802	-$102,920,571	$16,804,932	$26,646,544	$11.46	173
2023 Q1	41,579,108	$837,317,405	+$27,836,492	$13,256,148	$28,159,748	$20.14	170
2022 Q4	40,238,914	$912,094,750	-$33,364,677	$11,702,254	$50,851,077	$22.67	174
2022 Q3	42,072,015	$789,027,381	+$16,257,084	$5,869,456	$34,198,396	$18.76	155
2022 Q2	40,495,580	$754,734,025	+$52,181,297	$7,186,984	$40,886,944	$18.64	161
2022 Q1	37,951,511	$685,692,734	+$3,739,840	$8,479,782	$27,318,441	$18.07	162
2021 Q4	37,700,468	$782,152,012	-$10,555,469	$15,509,524	$104,678,720	$20.74	169
2021 Q3	37,029,922	$1,185,365,197	+$36,464,815	$17,264,000	$158,571,407	$32.01	170
2021 Q2	35,921,387	$1,106,406,897	-$14,666,760	$23,075,000	$147,300,000	$30.8	153
2021 Q1	36,324,502	$1,223,768,350	+$31,780,970	$15,378,000	$115,772,200	$33.69	153
2020 Q4	34,974,972	$1,263,910,909	-$11,650,805	$19,974,000	$72,650,738	$36.13	160
2020 Q3	35,272,720	$1,298,543,100	-$827,360	$22,082,000	$89,223,000	$36.83	157
2020 Q2	34,963,826	$1,573,348,794	-$20,279,224	$52,146,000	$93,186,000	$45.06	172
2020 Q1	35,310,616	$1,675,810,163	-$22,488,569	$40,427,000	$83,209,000	$47.45	167
2019 Q4	34,655,343	$2,483,224,906	+$183,794,307	$40,724,000	$119,006,000	$71.66	179
2019 Q3	32,038,308	$1,260,902,231	+$155,277,735	$19,944,000	$151,524,000	$39.36	155
2019 Q2	26,449,920	$2,066,161,619	+$440,721,480	$73,299,345	$324,346,000	$78.15	143
2019 Q1	22,704,127	$1,354,292,705	+$7,107,528	$14,435,000	$128,309,000	$59.65	128
2018 Q4	22,760,640	$655,512,079	-$4,279,771	$4,384,000	$44,297,000	$28.82	93
2018 Q3	22,572,035	$821,994,896	+$5,790,048	$4,000,000	$76,580,000	$36.39	98
2018 Q2	22,030,252	$832,692,000	+$220,229,387	$2,465,000	$79,202,000	$37.8	94
2018 Q1	16,267,232	$382,280,000	+$66,881,880	$1,168,000	$17,097,000	$23.5	66
2017 Q4	13,549,875	$265,453,073	+$106,494,269	$1,955,000	$11,065,000	$19.59	60
2017 Q3	7,666,082	$73,561,120	+$258,592			$9.6	35
2017 Q2	7,650,235	$47,354,000	+$3,032,085			$6.19	31
2017 Q1	7,213,970	$41,691,000	-$1,974,062	$1,000		$5.78	37
2016 Q4	7,619,508	$42,662,000	-$3,166,022	$2,000	$0	$5.6	50
2016 Q3	7,075,534	$54,129,000	-$8,015,435	$16,000	$142,000	$7.65	48
2016 Q2	8,137,564	$59,960,000	-$8,779,594	$202,000	$0	$7.37	57
2016 Q1	9,135,928	$108,531,000	+$7,848,398	$241,000	$126,000	$11.88	56
2015 Q4	8,219,077	$135,936,000	-$884,886	$1,830,000	$5,439,000	$16.54	64
2015 Q3	7,929,168	$162,145,000	-$249,360	$1,370,000	$7,128,000	$20.45	62
2015 Q2	7,678,180	$207,309,000	+$75,445,120	$578,000	$227,000	$27	53
2015 Q1	4,924,505	$119,703,000	+$32,132,767			$24.32	40
2014 Q4	3,821,918	$56,602,200	+$6,865,008			$14.81	27
2014 Q3	3,456,020	$31,869,000	-$65,722			$9.24	26
2014 Q2	3,422,576	$46,512,000	+$44,407			$13.59	26
2014 Q1	3,341,209	$51,981,000	+$51,981,000			$15.55	24