Security Snapshot

uniQure N.V. - Ordinary Shares, par value 0.05 euro (QURE) Institutional Ownership

CUSIP: N90064101

13F Institutional Holders and Ownership History from Q1 2014 to Q2 2026

Latest Period

Q2 2026

Institutions Reporting

254

Shares (Excl. Options)

65,397,049

Price

$46.06

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Latest holder snapshot 5 signals
Portfolio coverage rank
0.01%
Share change
+5,720,348
Value change
+$395,135,921
Number of holders
254
Issuer context Names, identifiers, and filing context for this profile. 3 identity fields
Shares outstanding
69,150,386
SEC-reported price per share
$45.13
Insider filing price
$45.13
13F Shares, Excluding Options vs Price
13F Value, Excluding Options
Total Investors

Key facts

  • QURE - uniQure N.V. - Ordinary Shares, par value 0.05 euro is tracked under CUSIP N90064101.
  • 254 institutions reported positions in Q2 2026.
  • 9 significant owners is listed from Schedule 13D/13G reporting.

Change

  • Holder count moved from 212 to 254 between Q1 2026 and Q2 2026.
  • SEC-reported value moved from $971,033,032 to $3,018,805,332.

Research use

  • You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
  • 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.

Evidence

Source: SEC Form 13F

Latest holder context comes from 254 institutions filings for Q2 2026.

Open SEC evidence

Security key

N90064101

Latest holder period

Q2 2026

13F holders

254

13D/G owners

9

CIK / CUSIP context first

13D/G owners

Significant owners

Large-stake holder rows connected to Schedule 13D/G evidence.

Rows
9
Security
QURE
Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
Avoro Capital Advisors LLC 9.9% +47% $143,848,500 +$59,059,750 6,150,000 +70% Avoro Capital Advisors LLC 31 Dec 2025
JPMORGAN CHASE & CO 7% $224,134,759 4,866,211 JPMORGAN CHASE & CO 30 Jun 2026
RTW INVESTMENTS, LP 5.7% +40% $168,029,214 +$57,772,858 3,941,572 +52% RTW Investments, LP 30 Jun 2026
SUSQUEHANNA SECURITIES, LLC 4.8% -15% $142,351,418 -$8,408,938 3,339,231 -5.6% G1 Execution Services, LLC 30 Jun 2026
Aberdeen Group plc 4.5% -50% $131,184,269 -$113,227,870 2,848,117 -46% Aberdeen Group plc 30 Jun 2026
STATE STREET CORP 3.6% -32% $40,508,375 -$17,391,916 2,260,512 -30% STATE STREET CORPORATION 31 Mar 2026
Nantahala Capital Management, LLC 3.8% -40% $29,546,669 -$13,394,318 2,051,852 -31% Nantahala Capital Management, LLC 30 Jun 2025
FMR LLC 2.8% -70% $31,249,037 -$77,338,527 1,743,808 -71% FMR LLC 31 Mar 2026
Vestal Point Capital, LP 0.4% -91% $13,133,250 -$202,835,750 225,000 -94% Vestal Point Capital, LP 30 Sep 2025

As of 30 Jun 2026, 254 institutional investors reported holding 65,397,049 shares of uniQure N.V. - Ordinary Shares, par value 0.05 euro (QURE). This represents 95% of the company’s total 69,150,386 outstanding shares.

13F concentration

Top 25 institutional shareholders

Largest 13F positions for this security by reported shares and value.

Top holder share
66%
Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
Avoro Capital Advisors LLC 9.7% 6,727,777 +13% 2.8% $309,881,409
JPMORGAN CHASE & CO 7% 4,867,755 +72% 0.01% $230,813,250
RTW INVESTMENTS, LP 5.7% 3,941,572 +52% 1.5% $181,548,806
STATE STREET CORP 4.2% 2,903,825 +28% 0% $133,750,180
Aberdeen Group plc 4.1% 2,848,117 -46% 0.18% $131,184,269
BlackRock, Inc. 2.7% 1,877,453 +8.3% 0% $86,475,484
ORBIMED ADVISORS LLC 2.6% 1,807,486 -15% 1.6% $83,252,805
JANE STREET GROUP, LLC 2.3% 1,610,483 +153% 0.05% $74,178,847
JENNISON ASSOCIATES LLC 2.3% 1,561,412 +27% 0.04% $71,918,636
Boxer Capital Management, LLC 2.2% 1,503,300 +127% 5.2% $69,241,998
GOLDMAN SACHS GROUP INC 2.1% 1,475,956 +17% 0.01% $67,982,533
TWO SIGMA INVESTMENTS, LP 2.1% 1,462,024 -45% 0.05% $67,340,825
Two Seas Capital LP 2.1% 1,441,410 +11% 2.5% $66,391,345
FMR LLC 1.8% 1,270,068 -27% 0% $58,499,338
MAK CAPITAL ONE LLC 1.8% 1,232,051 +179% 8% $56,748,269
MPM BIOIMPACT LLC 1.8% 1,225,855 -10% 3.4% $56,462,881
MORGAN STANLEY 1.5% 1,066,639 +191% 0% $49,129,407
Vestal Point Capital, LP 1.4% 935,000 +160% 1% $43,066,100
MAVERICK CAPITAL LTD 1.3% 925,383 +33% 0.38% $42,623,141
CITADEL ADVISORS LLC 1.3% 910,338 +125% 0.02% $41,930,168
Fiera Capital Corp 1.3% 909,141 +11% 0.15% $41,875,034
Integral Health Asset Management, LLC 1.3% 900,000 0% 1.7% $41,454,000
GEODE CAPITAL MANAGEMENT, LLC 1.2% 860,631 +7% 0% $39,658,136
Longaeva Partners L.P. 1.2% 804,594 1.1% $37,059,600
VANGUARD CAPITAL MANAGEMENT LLC 1.1% 779,779 +12% 0% $35,916,621

Quarter history

Institutional holders across reporting periods

Holder count, reported shares/value, and median price by quarter.

Periods
50
Latest
Q2 2026
Rows shown
1-25 of 50
Period 13F Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2026 Q2 65,397,049 $3,018,805,332 +$395,135,921 $46.06 254
2026 Q1 59,679,012 $971,033,032 -$92,223,024 $16.35 212
2025 Q4 61,851,820 $1,480,105,175 -$115,090,755 $23.93 223
2025 Q3 55,352,343 $3,231,367,488 +$237,515,957 $58.37 218
2025 Q2 52,961,222 $738,302,097 +$50,637,556 $13.94 143
2025 Q1 49,986,625 $532,054,267 +$84,767,075 $10.60 139
2024 Q4 41,605,808 $734,372,507 +$59,578,946 $17.66 136
2024 Q3 38,874,270 $192,931,529 +$40,181,251 $4.93 129
2024 Q2 31,728,639 $141,844,153 -$3,825,259 $4.48 112
2024 Q1 32,322,300 $168,079,173 -$35,691,371 $5.20 130
2023 Q4 37,687,636 $255,220,282 -$8,276,086 $6.77 143
2023 Q3 35,800,237 $240,082,030 -$11,389,007 $6.71 160
2023 Q2 35,929,422 $411,603,802 -$102,920,571 $11.46 173
2023 Q1 41,579,108 $837,317,405 +$27,836,492 $20.14 170
2022 Q4 40,238,914 $912,094,750 -$33,364,677 $22.67 174
2022 Q3 42,072,015 $789,027,381 +$16,257,084 $18.76 155
2022 Q2 40,495,580 $754,734,025 +$52,181,297 $18.64 161
2022 Q1 37,951,511 $685,692,734 +$3,739,840 $18.07 162
2021 Q4 37,700,468 $782,152,012 -$10,555,469 $20.74 169
2021 Q3 37,029,922 $1,185,365,197 +$36,464,815 $32.01 170
2021 Q2 35,921,387 $1,106,406,897 -$14,666,760 $30.80 153
2021 Q1 36,324,502 $1,223,768,350 +$31,780,970 $33.69 153
2020 Q4 34,974,972 $1,263,910,909 -$11,650,805 $36.13 160
2020 Q3 35,272,720 $1,298,543,100 -$827,360 $36.83 157
2020 Q2 34,963,826 $1,573,348,794 -$20,279,224 $45.06 172
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