| Reporting Name | Ownership % | Change | Value $ | Shares owned | Change | Activity % | Price | Form | Report date | Filing time |
|---|---|---|---|---|---|---|---|---|---|---|
| RTW Investments, LP | 3.1% | -48% | $165,312,089 | 1,516,903 | -1,405,826 | -48% | $108.98 | 13G/A | 30 Jun 2025 | 14 Aug 2025, 08:02 |
| RTW Investments, LP | 6% | -30% | $321,266,372 | 2,922,729 | -1,128,636 | -28% | $109.92 | 13G/A | 31 Mar 2025 | 15 May 2025, 08:09 |
| RTW Investments, LP | 8.4% | $445,326,041 | 4,051,365 | $109.92 | 13G/A | 31 Dec 2024 | 14 Feb 2025, 09:00 |
| Holdings date | Option | Weight | Change | Value $ | Shares | Change | Activity % | Price | All Holders |
|---|---|---|---|---|---|---|---|---|---|
| 31 Dec 2025 | 1.6% | -0.42% | $162,184,503 | 888,001 | -230,882 | -21% | $182.64 | Q4 2025 | |
| 30 Sep 2025 | 1.7% | -0.6% | $135,888,340 | 1,118,883 | -398,020 | -26% | $121.45 | Q3 2025 | |
| 30 Jun 2025 | 2.3% | -2.1% | $158,349,504 | 1,516,903 | -1,405,826 | -48% | $104.39 | Q2 2025 | |
| 31 Mar 2025 | 5.2% | -2% | $340,877,883 | 2,922,729 | -1,128,636 | $116.63 | Q1 2025 | ||
| 31 Dec 2024 | 5.2% | -0.18% | $342,785,993 | 4,051,365 | -138,192 | -3.3% | $84.61 | Q4 2024 | |
| 30 Sep 2024 | 5.4% | -0.58% | $376,515,488 | 4,189,557 | -444,774 | -9.6% | $89.87 | Q3 2024 | |
| 30 Jun 2024 | 5.8% | +0.17% | $373,063,646 | 4,634,331 | +141,652 | +3.2% | $80.50 | Q2 2024 | |
| 31 Mar 2024 | 5.3% | +0% | $358,515,784 | 4,492,679 | +3,083 | +0.07% | $79.80 | Q1 2024 | |
| 31 Dec 2023 | 5.6% | 0% | $357,326,946 | 4,489,596 | 0 | $79.59 | Q4 2023 | ||
| 30 Sep 2023 | 6.6% | +0.3% | $313,777,864 | 4,489,596 | +205,319 | +4.8% | $69.89 | Q3 2023 | |
| 30 Jun 2023 | 5.9% | +0.69% | $307,868,145 | 4,284,277 | +503,422 | +13% | $71.86 | Q2 2023 | |
| 31 Mar 2023 | 4.9% | +1% | $233,203,136 | 3,780,855 | +800,373 | +27% | $61.68 | Q1 2023 | |
| 31 Dec 2022 | 4.7% | +1.7% | $229,884,577 | 2,980,482 | +1,098,318 | +58% | $77.13 | Q4 2022 | |
| 30 Sep 2022 | 1.9% | +0.27% | $83,982,000 | 1,882,164 | +263,345 | +16% | $44.62 | Q3 2022 | |
| 30 Jun 2022 | 1.6% | 0% | $62,001,000 | 1,618,819 | 0 | $38.30 | Q2 2022 | ||
| 31 Mar 2022 | 1.4% | 0% | $67,003,000 | 1,618,819 | 0 | $41.39 | Q1 2022 | ||
| 31 Dec 2021 | 0.89% | +0% | $61,159,000 | 1,618,819 | +2,322 | +0.14% | $37.78 | Q4 2021 | |
| 30 Sep 2021 | 0.8% | 0% | $53,280,000 | 1,616,497 | 0 | $32.96 | Q3 2021 | ||
| 30 Jun 2021 | 1.6% | 0% | $109,049,000 | 1,616,497 | 0 | $67.46 | Q2 2021 | ||
| 31 Mar 2021 | 1.4% | -0.05% | $91,526,000 | 1,616,497 | -55,919 | -3.3% | $56.62 | Q1 2021 | |
| 31 Dec 2020 | 2.3% | +0% | $136,252,000 | 1,672,416 | +1,478 | +0.09% | $81.47 | Q4 2020 | |
| 30 Sep 2020 | 2.9% | +0.02% | $119,054,000 | 1,670,938 | +12,622 | +0.76% | $71.25 | Q3 2020 | |
| 30 Jun 2020 | 3.8% | +1.4% | $136,446,000 | 1,658,316 | +605,347 | +57% | $82.28 | Q2 2020 | |
| 31 Mar 2020 | 2.7% | +0.07% | $61,946,000 | 1,052,969 | +26,156 | +2.5% | $58.83 | Q1 2020 | |
| 31 Dec 2019 | 4% | +0.71% | $106,131,000 | 1,026,813 | +180,692 | +21% | $103.36 | Q4 2019 | |
| 30 Sep 2019 | 1% | +0% | $17,125,000 | 846,121 | +1,832 | +0.22% | $20.24 | Q3 2019 | |
| 30 Jun 2019 | 1.2% | +0.34% | $21,740,000 | 844,289 | +248,654 | +42% | $25.75 | Q2 2019 | |
| 31 Mar 2019 | 0.58% | +0.58% | $8,476,000 | 595,635 | +595,635 | NEW | $14.23 | Q1 2019 |