Orchestra BioMed Holdings, Inc. - Common Stock, par value $0.0001 per share (OBIO)

Historical Holders from Q4 2022 to Q4 2025

Type / Class
Equity / Common Stock, par value $0.0001 per share
Symbol
OBIO on Nasdaq
Shares outstanding
56,338,036
Price per share
$4.31
All holders as of 30 Sep 2025
Q3 2025
Total 13F shares as of 30 Sep 2025
22,464,285
Holdings value
$55,746,866
% of all portfolios
0%
Share change
+4,786,648
Value change
+$11,822,209
Average buys %
+0%
Average sells %
-0%
Number of holders
50
Price from insider filings
$4.31
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of Orchestra BioMed Holdings, Inc. - Common Stock, par value $0.0001 per share (OBIO) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
RTW INVESTMENTS, LP 15% -29% $22,260,249 8,306,063 0% RTW Investments, LP 04 Aug 2025
Medtronic plc 15% $14,848,357 5,868,916 Medtronic plc 31 Dec 2024
PERCEPTIVE ADVISORS LLC 10% $14,085,110 5,679,480 Perceptive Advisors LLC 30 Sep 2025
Tasso Partners, LLC 5.5% $7,684,508 3,098,592 Dana Lorenzo 15 Nov 2025
BlackRock, Inc. 3.7% $3,619,674 1,430,701 BlackRock, Inc. 31 Mar 2025
As of 30 Sep 2025, Orchestra BioMed Holdings, Inc. - Common Stock, par value $0.0001 per share (OBIO) has 50 institutional shareholders filing 13F forms. They hold 22,464,285 shares of 56,338,036 outstanding shares (40%) .

Top 25 institutional shareholders own 39% of the company.

Filer Ownership Nb Shares Share Change % Portfolio % Holdings Value
RTW INVESTMENTS, LP 15% 8,306,063 +0% 0.25% $20,599,036
PERCEPTIVE ADVISORS LLC 9.4% 5,292,556 +15% 0.38% $13,125,539
VANGUARD GROUP INC 2.6% 1,481,875 +28% 0% $3,675,050
Alyeska Investment Group, L.P. 2.4% 1,365,482 0.01% $3,386,395
Pathstone Holdings, LLC 1.8% 1,006,018 0.01% $2,494,924
Affinity Asset Advisors, LLC 1.3% 727,272 0.17% $1,803,635
BlackRock, Inc. 1.2% 664,333 -2.5% 0% $1,647,546
PRICE T ROWE ASSOCIATES INC /MD/ 0.75% 421,612 -3.8% 0% $1,046,000
GEODE CAPITAL MANAGEMENT, LLC 0.69% 386,799 +28% 0% $959,585
RENAISSANCE TECHNOLOGIES LLC 0.68% 380,508 +125% 0% $943,660
MILLENNIUM MANAGEMENT LLC 0.66% 373,987 -8.7% 0% $927,488
DAFNA Capital Management LLC 0.65% 363,636 0.22% $901,817
Knott David M Jr 0.35% 195,000 +95% 0.2% $483,600
CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.32% 180,439 +30% 0% $447,489
AMH Equity Ltd 0.29% 166,000 0.52% $411,680
NORTHERN TRUST CORP 0.18% 102,572 +2.1% 0% $254,379
STATE STREET CORP 0.18% 100,733 -23% 0% $249,818
SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.17% 98,105 -17% 0% $243,300
TD Asset Management Inc 0.16% 92,678 0% 0% $229,841
IFP Advisors, Inc 0.15% 86,698 +1.6% 0.01% $215,011
Cubist Systematic Strategies, LLC 0.14% 77,892 +340% 0% $193,172
JANE STREET GROUP, LLC 0.12% 65,524 +254% 0% $162,499
LASRY MARC 0.11% 60,869 0% 1% $150,955
CITADEL ADVISORS LLC 0.1% 54,002 +9.2% 0% $133,925
Holos Integrated Wealth LLC 0.09% 51,595 0% 0.1% $162,524

Institutional Holders of Orchestra BioMed Holdings, Inc. - Common Stock, par value $0.0001 per share (OBIO) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price Investors
2025 Q4 51,595 $222,374 $4.31 1
2025 Q3 22,464,285 $55,746,866 +$11,822,209 $2.48 50
2025 Q2 17,679,478 $47,383,339 -$3,869,274 $2.68 57
2025 Q1 18,991,589 $81,285,133 -$1,022,777 $4.28 55
2024 Q4 19,251,082 $77,005,657 -$602,359 $4.00 53
2024 Q3 19,025,849 $97,782,881 +$23,796,821 $5.14 47
2024 Q2 14,216,993 $115,871,788 +$7,254,151 $8.15 46
2024 Q1 13,334,624 $70,275,199 +$299,341 $5.27 42
2023 Q4 13,269,980 $121,156,215 +$1,621,325 $9.13 39
2023 Q3 13,093,349 $114,176,966 +$20,438,436 $8.72 42
2023 Q2 10,783,562 $75,485,512 +$5,117,242 $7.00 39
2023 Q1 9,872,658 $193,184,972 +$179,728,876 $19.57 22
2022 Q4 685,801 $6,851,000 +$6,851,000 $9.99 1