Security Snapshot

Xencor Inc - Common Stock, par value $0.01 per share (XNCR) Institutional Ownership

CUSIP: 98401F105

13F Institutional Holders and Ownership History from Q1 2014 to Q1 2026

Latest Period

Q4 2025

Institutions Reporting

203

Shares (Excl. Options)

81,824,146

Price

$15.31

Save this security page for your next review

Keep this CUSIP in your watchlists so you can revisit quarter changes from one place. If you create an account from here, we will bring you back after verification.

Type / Class
Equity / Common Stock, par value $0.01 per share
Symbol
XNCR on Nasdaq
Shares outstanding
72,872,908
Price per share
$12.07
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
81,824,146
Total reported value
$1,252,496,497
% of total 13F portfolios
0%
Share change
-1,616,891
Value change
-$15,445,435
Number of holders
203
Price from insider filings
$12.07
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Quick Takeaways

  • XNCR - Xencor Inc - Common Stock, par value $0.01 per share is tracked under CUSIP 98401F105.
  • 203 institutions reported positions in Q4 2025.
  • 8 significant owners is listed from Schedule 13D/13G reporting.

What Changed

  • Holder count moved from 203 to 81 between Q4 2025 and Q1 2026.
  • Reported value moved from $1,252,496,497 to $173,202,380.

Why This Matters

  • You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
  • 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.

Source Evidence

Source: SEC Form 13F

Latest holder context comes from 203 institutions filings for Q4 2025.

Open SEC Evidence

Investment Quick Answers

What is CUSIP 98401F105?
CUSIP 98401F105 identifies XNCR - Xencor Inc - Common Stock, par value $0.01 per share in SEC 13F datasets.

Where can I see the latest institutional holders?
Review the Q4 2025 holders report and the ownership history table below.

Significant Owners of Xencor Inc - Common Stock, par value $0.01 per share (XNCR) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
BlackRock, Inc. 16% -9.4% $116,977,477 -$11,261,518 11,130,112 -8.8% BlackRock, Inc. 31 Mar 2025
PRIMECAP MANAGEMENT CO/CA/ 15% $98,219,914 10,527,322 PRIMECAP MANAGEMENT CO/CA/ 30 Jun 2025
BIOTECHNOLOGY VALUE FUND L P 10% +50% $109,217,253 +$38,495,142 7,133,720 +54% BVF PARTNERS L P/IL 31 Dec 2025
RTW INVESTMENTS, LP 8.7% $72,972,963 6,221,054 RTW Investments, LP 30 Sep 2025
RA CAPITAL MANAGEMENT, L.P. 6.5% $58,261,890 4,736,739 RA Capital Management, L.P. 23 Mar 2026
EcoR1 Capital, LLC 6.4% $71,038,400 4,640,000 EcoR1 Capital, LLC 31 Dec 2025
STATE STREET CORP 6.3% +22% $69,006,059 +$12,608,382 4,507,254 +22% STATE STREET CORPORATION 31 Dec 2025
PRICE T ROWE ASSOCIATES INC /MD/ 2.4% $19,862,315 1,693,292 T. Rowe Price Associates, Inc. 30 Sep 2025

As of 31 Dec 2025, 203 institutional investors reported holding 81,824,146 shares of Xencor Inc - Common Stock, par value $0.01 per share (XNCR). This represents 112% of the company’s total 72,872,908 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of Xencor Inc - Common Stock, par value $0.01 per share (XNCR) together control 96% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
BlackRock, Inc. 16% 11,927,218 +1% 0% $182,605,708
PRIMECAP MANAGEMENT CO/CA/ 14% 10,218,322 -4.3% 0.12% $156,442,509
VANGUARD GROUP INC 9.8% 7,165,450 +0.87% 0% $109,703,040
BVF INC/IL 9.8% 7,133,720 +160% 3.7% $109,217,253
RTW INVESTMENTS, LP 9.3% 6,777,461 +8.9% 1% $103,762,928
STATE STREET CORP 6.2% 4,507,254 +23% 0% $69,006,059
EcoR1 Capital, LLC 4.5% 3,251,112 -47% 2.3% $49,774,525
TCG Crossover Management, LLC 3.4% 2,452,138 0% 1.2% $37,542,233
GEODE CAPITAL MANAGEMENT, LLC 2.4% 1,752,918 +1.4% 0% $26,842,201
PRICE T ROWE ASSOCIATES INC /MD/ 2.2% 1,601,762 -5.4% 0% $24,524,000
MORGAN STANLEY 2.1% 1,508,727 +67% 0% $23,098,626
Defilade Capital Management, L.P. 1.9% 1,414,755 0% 2.9% $21,659,899
Legal & General Group Plc 1.8% 1,308,088 +2.8% 0% $20,026,828
DIMENSIONAL FUND ADVISORS LP 1.7% 1,249,288 -21% 0% $19,125,117
BAKER BROS. ADVISORS LP 1.5% 1,102,106 0% 0.1% $16,873,243
GOLDMAN SACHS GROUP INC 1% 753,258 -26% 0% $11,532,380
JOHNSON & JOHNSON 1% 748,062 0% 2.1% $11,452,829
Jefferies Financial Group Inc. 0.99% 720,440 +620% 0.09% $11,029,936
Lynx1 Capital Management LP 0.97% 705,558 2.2% $10,802,093
CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.96% 700,435 +1.8% 0% $10,723,660
NORTHERN TRUST CORP 0.93% 674,657 -5.3% 0% $10,328,998
UBS Group AG 0.88% 638,021 -46% 0% $9,768,101
BANK OF AMERICA CORP /DE/ 0.86% 629,408 -17% 0% $9,636,237
MILLENNIUM MANAGEMENT LLC 0.82% 594,435 -15% 0.01% $9,100,800
PANAGORA ASSET MANAGEMENT INC 0.8% 583,778 -6% 0.03% $8,937,641

Institutional Holders of Xencor Inc - Common Stock, par value $0.01 per share (XNCR) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2026 Q1 14,370,724 $173,202,380 +$1,182,871 $12.06 81
2025 Q4 81,824,146 $1,252,496,497 -$15,445,435 $15.31 203
2025 Q3 81,931,427 $960,178,354 +$6,100,028 $11.73 204
2025 Q2 82,284,537 $646,977,988 +$20,020,454 $7.86 191
2025 Q1 78,656,178 $836,867,995 +$36,707,472 $10.64 197
2024 Q4 74,962,874 $1,722,861,698 +$74,554,042 $22.98 191
2024 Q3 72,099,278 $1,450,233,173 +$173,590,110 $20.11 209
2024 Q2 63,677,276 $1,205,414,340 -$28,620,202 $18.93 197
2024 Q1 64,955,561 $1,437,354,893 +$38,858,883 $22.13 200
2023 Q4 63,438,288 $1,346,794,541 +$2,946,816 $21.23 194
2023 Q3 63,240,815 $1,274,307,664 +$10,877,356 $20.15 175
2023 Q2 62,681,983 $1,566,006,651 -$23,444,287 $24.97 180
2023 Q1 63,583,668 $1,771,628,071 +$59,782,147 $27.89 183
2022 Q4 61,547,949 $1,602,582,831 +$19,403,618 $26.04 193
2022 Q3 60,849,265 $1,581,417,958 -$74,640,726 $25.98 174
2022 Q2 59,843,119 $1,638,192,397 +$20,569,513 $27.37 168
2022 Q1 59,286,835 $1,582,158,680 -$1,530,095 $26.68 169
2021 Q4 59,174,089 $2,372,958,496 +$30,709,697 $40.12 171
2021 Q3 58,120,007 $1,898,467,165 +$947,702 $32.66 165
2021 Q2 58,041,765 $2,001,234,431 -$24,285,884 $34.49 173
2021 Q1 58,525,232 $2,519,282,177 -$25,684,890 $43.06 167
2020 Q4 59,098,973 $2,579,349,505 +$122,069 $43.63 169
2020 Q3 59,168,606 $2,295,311,877 +$21,234,216 $38.79 157
2020 Q2 58,636,892 $1,899,277,122 +$203,952,745 $32.39 151
2020 Q1 52,380,712 $1,565,845,143 -$41,704,286 $29.88 137
2019 Q4 53,521,828 $1,840,592,912 -$9,705,040 $34.39 162
2019 Q3 53,716,146 $1,811,934,409 +$147,436,205 $33.73 150
2019 Q2 48,892,888 $2,001,111,237 +$50,462,146 $40.93 118
2019 Q1 48,039,063 $1,492,133,555 +$4,125,992 $31.06 115
2018 Q4 47,831,492 $1,729,047,723 +$32,118,652 $36.16 115
2018 Q3 46,792,493 $1,822,675,621 +$3,293,406 $38.97 124
2018 Q2 46,774,405 $1,731,076,239 +$86,469,155 $37.01 122
2018 Q1 44,718,509 $1,340,651,579 +$224,063,089 $29.98 122
2017 Q4 37,369,817 $819,172,426 +$3,577,339 $21.92 104
2017 Q3 37,140,169 $851,162,220 +$9,732,952 $22.92 104
2017 Q2 36,836,630 $777,612,692 +$23,377,905 $21.11 114
2017 Q1 35,650,517 $852,741,478 +$81,080,319 $23.92 125
2016 Q4 35,035,653 $922,088,537 +$142,823,588 $26.32 136
2016 Q3 29,626,637 $724,863,086 +$38,489,120 $24.49 120
2016 Q2 28,213,616 $535,759,236 +$3,771,990 $18.99 99
2016 Q1 28,006,868 $375,809,000 +$24,280,734 $13.42 91
2015 Q4 26,171,247 $382,476,117 -$27,011,932 $14.62 93
2015 Q3 28,373,464 $347,020,935 +$34,279,194 $12.23 93
2015 Q2 25,251,465 $554,774,155 +$49,843,256 $21.97 97
2015 Q1 23,319,707 $357,257,260 +$137,738,740 $15.32 94
2014 Q4 14,119,842 $225,905,985 +$7,473,629 $16.04 63
2014 Q3 13,435,605 $124,719,599 +$5,776,557 $9.31 50
2014 Q2 12,796,476 $148,692,713 -$25,746,421 $11.62 51
2014 Q1 15,007,873 $176,041,000 +$18,181,068 $11.73 43
We use cookies and similar technologies to provide certain features, enhance the user experience and, if you allow them, measure engagement and deliver advertising. Analytics and marketing storage stay off until you grant consent. By clicking on "Agree and continue", you declare your consent to the use of the selected optional cookies. Here you can make detailed settings or revoke your consent (in part if necessary) with effect for the future. For further information, please refer to our Privacy Policy .