Latest Period
Q2 2026
Security Snapshot
Protagonist Therapeutics, Inc - Common Stock, par value $0.00001 per share (the "Shares") (PTGX) Institutional Ownership
CUSIP: 74366E102
13F Institutional Holders and Ownership History from Q3 2016 to Q2 2026
Institutions Reporting
342
Shares (Excl. Options)
75,793,379
Price
$122.58
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- Security type / class
- Equity / Common Stock, par value $0.00001 per share (the "Shares")
- Symbol
- PTGX on Nasdaq
- All holders as of 30 Jun 2026
- Q2 2026
- Total 13F shares
- 75,793,379
- Total 13F value
- $9,289,568,188
- Portfolio coverage rank
- 0.01%
- Share change
- -2,337,531
- Value change
- -$228,964,348
- Number of holders
- 342
- Shares outstanding
- 64,395,586
- SEC-reported price per share
- $133.00
- Insider filing price
- $133.00
Latest holder snapshot
5 signals
Issuer context
Names, identifiers, and filing context for this profile.
3 identity fields
13F Shares, Excluding Options vs Price
13F Value, Excluding Options
Total Investors
Key facts
- PTGX - Protagonist Therapeutics, Inc - Common Stock, par value $0.00001 per share (the "Shares") is tracked under CUSIP 74366E102.
- 342 institutions reported positions in Q2 2026.
- 10 significant owners is listed from Schedule 13D/13G reporting.
Change
- Holder count moved from 320 to 342 between Q1 2026 and Q2 2026.
- SEC-reported value moved from $8,297,990,817 to $9,289,568,188.
Research use
- You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
- 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.
Evidence
Source: SEC Form 13F
Open SEC evidence
Latest holder context comes from 342 institutions filings for Q2 2026.
Security key
74366E102
Latest holder period
Q2 2026
13F holders
342
13D/G owners
10
CIK / CUSIP context first
Open Q2 2026 holders
PTGX full holder history
Protagonist Therapeutics, Inc SEC filings
Protagonist Therapeutics, Inc company facts
Protagonist Therapeutics, Inc insider transactions
Broader feeds
Recent Quarterly Holder Reports
Open recent reporting periods for CUSIP 74366E102:
13D/G owners
Significant owners
Large-stake holder rows connected to Schedule 13D/G evidence.
Rows
10
Security
PTGX
| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| BlackRock, Inc. | 14% | -6.7% | $569,681,692 | -$33,813,734 | 8,575,669 | -5.6% | BlackRock, Inc. | 30 Sep 2025 |
| FARALLON CAPITAL MANAGEMENT, L.L.C. | 10% | $835,597,827 | 6,433,119 | Farallon Capital Management, L.L.C. | 30 Jun 2026 | |||
| Farallon Capital Partners, L.P. | 10% | 0% | $545,701,455 | +$25,461,794 | 6,248,013 | +4.9% | Dapice Joshua J. | 31 Dec 2025 |
| RTW INVESTMENTS, LP | 8.1% | $405,989,003 | 5,059,053 | RTW Investments, LP | 31 Dec 2025 | |||
| VANGUARD PORTFOLIO MANAGEMENT LLC | 5.5% | $372,379,781 | 3,533,015 | Vanguard Portfolio Management | 31 Mar 2026 | |||
| STATE STREET CORP | 5.2% | +6% | $431,436,649 | +$26,594,978 | 3,321,554 | +6.6% | STATE STREET CORPORATION | 30 Jun 2026 |
| VANGUARD CAPITAL MANAGEMENT LLC | 5.1% | $342,550,316 | 3,250,003 | Vanguard Capital Management | 31 Mar 2026 | |||
| WELLINGTON MANAGEMENT GROUP LLP | 5.1% | $254,506,696 | 3,171,423 | Wellington Management Group LLP | 31 Dec 2025 | |||
| BIOTECHNOLOGY VALUE FUND L P | 4.1% | -22% | $170,121,650 | -$43,187,804 | 2,560,916 | -20% | BVF PARTNERS L P/IL | 30 Sep 2025 |
| Deep Track Capital, LP | 2.8% | -51% | $113,973,353 | -$101,924,147 | 1,715,691 | -47% | Deep Track Capital, LP | 30 Sep 2025 |
As of 30 Jun 2026, 342 institutional investors reported holding 75,793,379 shares of Protagonist Therapeutics, Inc - Common Stock, par value $0.00001 per share (the "Shares") (PTGX). This represents 118% of the company’s total 64,395,586 outstanding shares.
13F concentration
Top 25 institutional shareholders
Largest 13F positions for this security by reported shares and value.
Top holder share
94%
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| BlackRock, Inc. | 16% | 10,307,837 | +5.4% | 0.02% | $1,263,534,678 |
| FARALLON CAPITAL MANAGEMENT, L.L.C. | 9.9% | 6,348,906 | 0% | 4.6% | $778,248,897 |
| RTW INVESTMENTS, LP | 7.9% | 5,061,175 | +0.04% | 5.3% | $620,398,832 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 5.6% | 3,629,298 | +4.3% | 0.02% | $444,879,349 |
| WELLINGTON MANAGEMENT GROUP LLP | 5.3% | 3,416,781 | -5.1% | 0.07% | $418,829,015 |
| UBS Group AG | 5.3% | 3,399,221 | -34% | 0.07% | $416,676,511 |
| STATE STREET CORP | 5.2% | 3,321,554 | +6.6% | 0.01% | $407,156,089 |
| VANGUARD CAPITAL MANAGEMENT LLC | 4.4% | 2,853,394 | +1.7% | 0.01% | $349,769,037 |
| JOHNSON & JOHNSON | 3.8% | 2,449,183 | 0% | 38% | $300,220,852 |
| Invesco Ltd. | 3.6% | 2,340,667 | +8.1% | 0.02% | $286,918,961 |
| PRICE T ROWE ASSOCIATES INC /MD/ | 3.3% | 2,149,662 | +29% | 0.03% | $263,507,000 |
| Jupiter Topco LLC | 3.3% | 2,129,780 | 0% | 0.11% | $261,039,476 |
| GEODE CAPITAL MANAGEMENT, LLC | 2.7% | 1,741,209 | +4.3% | 0.01% | $213,475,772 |
| Woodline Partners LP | 2.2% | 1,414,173 | 0% | 0.54% | $173,349,326 |
| BANK OF AMERICA CORP /DE/ | 2.1% | 1,324,498 | +2.2% | 0.01% | $162,356,964 |
| JENNISON ASSOCIATES LLC | 1.8% | 1,151,681 | +7.4% | 0.08% | $141,173,058 |
| PERCEPTIVE ADVISORS LLC | 1.5% | 981,879 | -20% | 1.9% | $120,358,728 |
| ADAR1 Capital Management, LLC | 1.5% | 960,863 | -3.3% | 5.6% | $117,782,587 |
| MORGAN STANLEY | 1.4% | 905,992 | -11% | 0.01% | $111,056,578 |
| Alyeska Investment Group, L.P. | 1.4% | 889,298 | +50% | 0.28% | $109,010,149 |
| Hood River Capital Management LLC | 1.4% | 882,738 | +6.4% | 0.78% | $108,206,024 |
| GOLDMAN SACHS GROUP INC | 1.3% | 812,852 | +4.4% | 0.01% | $99,639,398 |
| Driehaus Capital Management LLC | 1.1% | 731,053 | +1.4% | 0.52% | $89,612,477 |
| Clearbridge Investments, LLC | 1.1% | 725,335 | +17% | 0.07% | $88,911,554 |
| FMR LLC | 1% | 672,186 | +1.5% | 0% | $82,396,533 |
Quarter history
Institutional holders across reporting periods
Holder count, reported shares/value, and median price by quarter.
Periods
40
Latest
Q2 2026
Rows shown
1-25 of 40
| Period | 13F Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2026 Q2 | 75,793,379 | $9,289,568,188 | -$228,964,348 | $122.58 | 342 |
| 2026 Q1 | 78,761,148 | $8,297,990,817 | +$703,980,404 | $105.40 | 320 |
| 2025 Q4 | 70,709,835 | $6,175,433,604 | +$99,663,953 | $87.34 | 311 |
| 2025 Q3 | 70,684,460 | $4,695,410,423 | +$4,458,380 | $66.43 | 274 |
| 2025 Q2 | 70,977,321 | $3,923,985,934 | +$344,775,786 | $55.27 | 273 |
| 2025 Q1 | 64,994,031 | $3,143,069,159 | +$116,416,679 | $48.36 | 273 |
| 2024 Q4 | 63,271,382 | $2,442,272,169 | +$44,242,054 | $38.60 | 240 |
| 2024 Q3 | 61,602,509 | $2,772,507,649 | -$40,480,651 | $45.00 | 238 |
| 2024 Q2 | 59,068,539 | $2,046,920,014 | -$15,105,959 | $34.65 | 187 |
| 2024 Q1 | 59,715,204 | $1,727,559,912 | +$80,356,864 | $28.93 | 183 |
| 2023 Q4 | 57,464,862 | $1,317,641,644 | +$12,220,647 | $22.93 | 155 |
| 2023 Q3 | 56,712,373 | $945,896,121 | -$53,252,231 | $16.68 | 142 |
| 2023 Q2 | 56,731,936 | $1,566,841,397 | +$104,873,016 | $27.62 | 163 |
| 2023 Q1 | 53,194,090 | $1,222,410,149 | +$179,899,701 | $23.00 | 135 |
| 2022 Q4 | 49,023,797 | $534,831,663 | +$12,387,471 | $10.91 | 135 |
| 2022 Q3 | 47,348,207 | $399,128,639 | -$50,141,212 | $8.43 | 129 |
| 2022 Q2 | 53,360,764 | $422,090,018 | -$73,694,821 | $7.91 | 125 |
| 2022 Q1 | 50,329,296 | $1,191,811,689 | -$6,168,618 | $23.68 | 136 |
| 2021 Q4 | 49,204,800 | $1,682,561,970 | +$93,460,895 | $34.20 | 144 |
| 2021 Q3 | 46,239,107 | $819,492,437 | -$246,905,195 | $17.72 | 126 |
| 2021 Q2 | 47,991,061 | $2,154,082,054 | +$179,883,058 | $44.88 | 136 |
| 2021 Q1 | 44,189,630 | $1,144,564,352 | +$27,791,318 | $25.90 | 124 |
| 2020 Q4 | 43,016,906 | $867,295,836 | +$98,827,896 | $20.16 | 124 |
| 2020 Q3 | 37,171,432 | $727,253,818 | +$62,067,302 | $19.55 | 91 |
| 2020 Q2 | 34,047,384 | $601,265,429 | +$210,058,150 | $17.66 | 82 |