Neurogene Inc. - Common Stock, $0.000001 par value (NGNE) Institutional Ownership

13F Institutional Holders and Ownership History from Q4 2023 to Q4 2025

Type / Class
Equity / Common Stock, $0.000001 par value
Symbol
NGNE on Nasdaq
Shares outstanding
15,729,081
Price per share
$18.89
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
16,492,025
Total reported value
$339,874,510
% of total 13F portfolios
0%
Share change
+409,818
Value change
+$9,470,657
Number of holders
92
Price from insider filings
$18.89
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of Neurogene Inc. - Common Stock, $0.000001 par value (NGNE) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
Redmile Group, LLC 9.9% 0% $32,077,887 +$1,594,708 1,557,179 +5.2% Redmile Group, LLC 31 Dec 2025
RTW INVESTMENTS, LP 10% $23,096,955 1,498,829 RTW Investments, LP 31 Dec 2024
EcoR1 Capital, LLC 9.9% $25,005,492 1,442,902 EcoR1 Capital, LLC 30 Sep 2025
Casdin Capital, LLC 8.7% $19,961,513 1,295,361 Casdin Capital, LLC 31 Dec 2024
BlackRock, Inc. 6.8% $15,586,229 1,011,436 BlackRock, Inc. 31 Mar 2025
BAKER BROS. ADVISORS LP 7% -30% $21,254,360 -$10,597,328 991,804 -33% Julian C. Baker 30 Jun 2025
Trails Edge Capital Partners, LP 5.1% $20,794,650 785,000 Trails Edge Capital Partners, LP 08 Dec 2025
FMR LLC 3.1% $7,132,965 462,879 FMR LLC 31 Mar 2025
GREAT POINT PARTNERS LLC 3% $6,822,947 442,761 Great Point Partners, LLC 31 Dec 2024
Commodore Capital LP 3% $9,169,168 427,866 Commodore Capital LP 30 Jun 2025

As of 31 Dec 2025, 92 institutional investors reported holding 16,492,025 shares of Neurogene Inc. - Common Stock, $0.000001 par value (NGNE). This represents 105% of the company’s total 15,729,081 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of Neurogene Inc. - Common Stock, $0.000001 par value (NGNE) together control 99% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
SAMSARA BIOCAPITAL, LLC 11% 1,717,127 0% 3.6% $35,372,816
Redmile Group, LLC 9.3% 1,459,599 +12% 2.2% $30,067,739
RTW INVESTMENTS, LP 8.7% 1,362,456 0% 0.28% $28,066,594
Casdin Capital, LLC 8.2% 1,295,361 0% 1.7% $26,684,437
EcoR1 Capital, LLC 8.1% 1,271,342 0% 1.2% $26,189,645
BAKER BROS. ADVISORS LP 6.3% 991,691 0% 0.12% $20,428,835
BlackRock, Inc. 6% 945,583 -0.58% 0% $19,479,009
Trails Edge Capital Partners, LP 5% 785,000 0% 4% $16,171,000
TORONTO DOMINION BANK 4.3% 681,337 0% 0.02% $14,035,542
VANGUARD GROUP INC 4.2% 656,572 +8.6% 0% $13,525,383
Balyasny Asset Management L.P. 3.9% 608,578 -13% 0.02% $12,536,710
ArrowMark Colorado Holdings LLC 3.7% 577,490 -3.1% 0.26% $11,896,294
JENNISON ASSOCIATES LLC 3.4% 533,088 +35% 0.01% $10,981,614
MORGAN STANLEY 2.4% 371,174 -13% 0% $7,646,185
CITADEL ADVISORS LLC 2.3% 364,228 0.01% $7,503,097
GREAT POINT PARTNERS LLC 2.2% 350,000 -22% 2.3% $7,210,000
STATE STREET CORP 2% 307,797 +48% 0% $6,340,618
GEODE CAPITAL MANAGEMENT, LLC 1.6% 249,695 +1.3% 0% $5,144,591
Logos Global Management LP 1.2% 195,000 0.27% $4,017,000
BLAIR WILLIAM & CO/IL 1% 163,655 +15% 0.01% $3,371,293
GOLDMAN SACHS GROUP INC 1% 162,018 +123% 0% $3,337,571
UBS Group AG 0.98% 154,123 -32% 0% $3,174,934
FMR LLC 0.83% 130,329 +13% 0% $2,684,777
Rock Springs Capital Management LP 0.66% 104,339 0% 0.11% $2,149,383
DEUTSCHE BANK AG\ 0.54% 85,571 -44% 0% $1,762,762

Institutional Holders of Neurogene Inc. - Common Stock, $0.000001 par value (NGNE) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 16,492,025 $339,874,510 +$9,470,657 $20.60 92
2025 Q3 15,299,947 $265,173,378 -$165,308 $17.33 88
2025 Q2 15,388,370 $230,113,281 -$13,642,147 $14.95 81
2025 Q1 16,456,922 $192,796,009 +$733,702 $11.71 83
2024 Q4 16,089,357 $367,798,856 +$14,465,324 $22.86 86
2024 Q3 13,847,659 $581,113,931 +$18,023,436 $41.96 85
2024 Q2 13,265,527 $482,740,723 +$37,443,874 $36.39 66
2024 Q1 12,128,797 $617,303,585 +$152,848,957 $50.90 58
2023 Q4 9,233,865 $178,953,482 +$178,848,733 $19.38 35