Latest Period
Q1 2026
Security Snapshot
Apellis Pharmaceuticals, Inc. - Common Stock (APLS) Institutional Ownership
CUSIP: 03753U106
13F Institutional Holders and Ownership History from Q4 2017 to Q1 2026
Institutions Reporting
312
Shares (Excl. Options)
137,129,679
Price
$40.23
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- Security type / class
- Equity / Common Stock
- Symbol
- APLS
- All holders as of 31 Mar 2026
- Q1 2026
- Total 13F shares
- 137,129,679
- Total 13F value
- $5,504,966,599
- Portfolio coverage rank
- 0.01%
- Share change
- +8,950,156
- Value change
- +$610,144,119
- Number of holders
- 312
- Shares outstanding
- 127,672,507
- SEC-reported price per share
- $41.12
- Insider filing price
- $41.12
Latest holder snapshot
5 signals
Issuer context
Names, identifiers, and filing context for this profile.
3 identity fields
13F Shares, Excluding Options vs Price
13F Value, Excluding Options
Total Investors
Key facts
- APLS - Apellis Pharmaceuticals, Inc. - Common Stock is tracked under CUSIP 03753U106.
- 312 institutions reported positions in Q1 2026.
- 6 significant owners is listed from Schedule 13D/13G reporting.
Change
- Holder count moved from 276 to 312 between Q4 2025 and Q1 2026.
- SEC-reported value moved from $3,169,569,402 to $5,504,966,599.
Research use
- You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
- 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.
Evidence
Source: SEC Form 13F
Open SEC evidence
Latest holder context comes from 312 institutions filings for Q1 2026.
Security key
03753U106
Latest holder period
Q1 2026
13F holders
312
13D/G owners
6
CIK / CUSIP context first
Broader feeds
Recent Quarterly Holder Reports
Open recent reporting periods for CUSIP 03753U106:
13D/G owners
Significant owners
Large-stake holder rows connected to Schedule 13D/G evidence.
Rows
6
Security
APLS
| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| BlackRock, Inc. | 10% | +120% | $332,289,194 | +$191,653,065 | 13,228,073 | +136% | BlackRock, Inc. | 31 Jan 2026 |
| STATE STREET CORP | 5.4% | $278,524,311 | 6,845,031 | STATE STREET CORPORATION | 31 Mar 2026 | |||
| Deep Track Capital, LP | 3.6% | -34% | $184,422,298 | -$100,407,702 | 4,532,374 | -35% | Deep Track Capital, LP | 31 Mar 2026 |
| RTW INVESTMENTS, LP | 2.9% | -53% | $149,944,481 | -$162,016,146 | 3,685,045 | -52% | RTW Investments, LP | 31 Mar 2026 |
| EcoR1 Capital, LLC | 2.7% | $78,009,140 | 3,447,156 | EcoR1 Capital, LLC | 30 Sep 2025 | |||
| WELLINGTON MANAGEMENT GROUP LLP | 0.2% | -97% | $10,042,791 | -$543,140,340 | 249,635 | -98% | Wellington Management Group LLP | 31 Mar 2026 |
As of 31 Mar 2026, 312 institutional investors reported holding 137,129,679 shares of Apellis Pharmaceuticals, Inc. - Common Stock (APLS). This represents 107% of the company’s total 127,672,507 outstanding shares.
13F concentration
Top 25 institutional shareholders
Largest 13F positions for this security by reported shares and value.
Top holder share
80%
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| BlackRock, Inc. | 11% | 13,536,964 | +116% | 0.01% | $544,592,062 |
| Avoro Capital Advisors LLC | 9.6% | 12,222,222 | 0% | 4.8% | $491,699,991 |
| MORGAN STANLEY | 7.9% | 10,042,399 | +9.5% | 0.02% | $404,005,720 |
| STATE STREET CORP | 5.4% | 6,844,990 | +48% | 0.01% | $275,373,948 |
| UBS Group AG | 4.9% | 6,206,681 | +48% | 0.04% | $249,694,778 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 4.2% | 5,404,559 | 0% | 0.01% | $217,425,409 |
| Pentwater Capital Management LP | 4.1% | 5,250,000 | 1.5% | $211,207,500 | |
| VANGUARD CAPITAL MANAGEMENT LLC | 3.7% | 4,768,944 | 0% | 0% | $191,854,617 |
| Deep Track Capital, LP | 3.6% | 4,532,374 | -42% | 3.8% | $182,337,406 |
| Point72 Asset Management, L.P. | 3.3% | 4,183,918 | +600% | 0.29% | $168,319,021 |
| RTW INVESTMENTS, LP | 2.9% | 3,685,045 | -52% | 1.5% | $148,249,360 |
| HBK INVESTMENTS L P | 2.8% | 3,550,000 | 1.8% | $142,816,500 | |
| SUVRETTA CAPITAL MANAGEMENT, LLC | 2.8% | 3,518,471 | -15% | 3.8% | $141,548,088 |
| MILLENNIUM MANAGEMENT LLC | 1.8% | 2,256,802 | +138% | 0.07% | $90,791,144 |
| GEODE CAPITAL MANAGEMENT, LLC | 1.6% | 2,075,075 | +2.4% | 0.01% | $83,502,254 |
| GOLDMAN SACHS GROUP INC | 1.6% | 1,980,144 | +947% | 0.01% | $79,661,193 |
| Balyasny Asset Management L.P. | 1.5% | 1,917,501 | +2844% | 0.15% | $77,141,065 |
| DIMENSIONAL FUND ADVISORS LP | 1% | 1,338,995 | +640% | 0.01% | $53,745,011 |
| GLAZER CAPITAL, LLC | 1% | 1,294,196 | 1.1% | $52,066,000 | |
| TIG Advisors, LLC | 0.98% | 1,252,986 | 2.4% | $50,407,627 | |
| TORONTO DOMINION BANK | 0.97% | 1,236,436 | 0.1% | $49,741,815 | |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | 0.94% | 1,202,100 | 0.08% | $48,360,483 | |
| BANK OF AMERICA CORP /DE/ | 0.93% | 1,190,864 | +24% | 0% | $47,908,459 |
| Hudson Bay Capital Management LP | 0.93% | 1,190,416 | +0.9% | 0.29% | $47,890,436 |
| FIL Ltd | 0.89% | 1,140,000 | 0.04% | $45,862,200 |
Quarter history
Institutional holders across reporting periods
Holder count, reported shares/value, and median price by quarter.
Periods
34
Latest
Q1 2026
Rows shown
1-25 of 34
| Period | 13F Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2026 Q1 | 137,129,679 | $5,504,966,599 | +$610,144,119 | $40.23 | 312 |
| 2025 Q4 | 126,342,513 | $3,169,569,402 | +$136,391,907 | $25.12 | 276 |
| 2025 Q3 | 122,308,038 | $2,770,590,650 | -$153,668,109 | $22.63 | 272 |
| 2025 Q2 | 131,608,288 | $2,279,077,423 | +$66,148,357 | $17.31 | 246 |
| 2025 Q1 | 126,465,800 | $2,767,959,579 | -$78,248,319 | $21.87 | 252 |
| 2024 Q4 | 126,723,891 | $4,044,170,293 | +$224,206,429 | $31.91 | 259 |
| 2024 Q3 | 118,165,642 | $3,408,098,233 | -$32,772,311 | $28.84 | 261 |
| 2024 Q2 | 115,428,997 | $4,426,484,074 | -$4,063,210 | $38.36 | 259 |
| 2024 Q1 | 113,103,917 | $6,646,510,438 | -$27,789,991 | $58.78 | 296 |
| 2023 Q4 | 113,568,311 | $6,800,298,011 | +$75,955,536 | $59.86 | 278 |
| 2023 Q3 | 113,630,426 | $4,326,001,749 | -$249,890,323 | $38.04 | 250 |
| 2023 Q2 | 106,464,737 | $9,698,740,546 | -$322,780,479 | $91.10 | 311 |
| 2023 Q1 | 110,363,167 | $7,278,027,538 | +$671,099,429 | $65.96 | 277 |
| 2022 Q4 | 100,652,525 | $5,202,853,976 | +$66,260,972 | $51.71 | 239 |
| 2022 Q3 | 97,643,165 | $6,665,378,163 | +$32,228,664 | $68.30 | 245 |
| 2022 Q2 | 91,648,969 | $4,144,516,571 | +$31,626,482 | $45.22 | 205 |
| 2022 Q1 | 90,940,512 | $4,620,842,334 | +$520,061,489 | $50.81 | 206 |
| 2021 Q4 | 81,021,271 | $3,829,991,538 | +$612,446,955 | $47.28 | 183 |
| 2021 Q3 | 69,511,931 | $2,291,947,609 | -$95,194,645 | $32.96 | 174 |
| 2021 Q2 | 64,601,991 | $4,083,171,314 | +$13,404,010 | $63.20 | 201 |
| 2021 Q1 | 63,358,839 | $2,718,377,161 | +$19,912,136 | $42.91 | 168 |
| 2020 Q4 | 63,890,305 | $3,654,164,157 | -$7,921,158 | $57.20 | 165 |
| 2020 Q3 | 62,139,394 | $1,874,756,231 | +$24,663,304 | $30.17 | 143 |
| 2020 Q2 | 61,184,997 | $1,997,919,282 | +$197,934,910 | $32.66 | 141 |
| 2020 Q1 | 55,273,539 | $1,482,076,889 | +$294,686,642 | $26.79 | 143 |