| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| BlackRock, Inc. | 7.2% | $34,471,350 | 4,425,077 | BlackRock, Inc. | 31 Mar 2025 | |||
| VANGUARD GROUP INC | 5.21% | -33.6% | $29,784,114 | -$14,339,987 | 3,265,802 | -32.5% | The Vanguard Group | 30 Jun 2025 |
| RTW INVESTMENTS, LP | 4.9% | $23,388,462 | 3,002,370 | RTW Investments, LP | 31 Dec 2024 | |||
| BB BIOTECH AG | 1.9% | $9,180,538 | 1,178,503 | BB Biotech AG | 13 Jan 2025 | |||
| MORGAN STANLEY | 1.6% | -82.9% | $7,886,105 | -$27,503,802 | 1,012,337 | -77.7% | Morgan Stanley | 28 Feb 2025 |
| FMR LLC | 0.8% | -84.3% | $3,902,130 | -$28,169,341 | 500,915 | -87.8% | FMR LLC | 28 Feb 2025 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Change | Price | Investors |
|---|---|---|---|---|---|
| 2025 Q3 | 26,706 | $494,024 | -$445,436,937 | $8.94 | 4 |
| 2025 Q2 | 48,874,647 | $445,736,286 | -$15,762,130 | $9.12 | 190 |
| 2025 Q1 | 51,753,624 | $411,497,036 | +$29,109,546 | $7.95 | 196 |
| 2024 Q4 | 51,167,791 | $277,852,513 | -$6,197,488 | $5.43 | 173 |
| 2024 Q3 | 51,256,195 | $370,077,943 | -$24,510,910 | $7.22 | 171 |
| 2024 Q2 | 53,511,146 | $581,112,272 | -$70,089,721 | $10.86 | 190 |
| 2024 Q1 | 58,440,998 | $1,095,196,207 | +$43,391,410 | $18.74 | 199 |
| 2023 Q4 | 56,110,184 | $1,215,929,511 | -$60,792,173 | $21.67 | 196 |
| 2023 Q3 | 58,785,676 | $1,209,823,569 | -$2,528,143 | $20.58 | 192 |
| 2023 Q2 | 54,096,461 | $2,543,396,226 | +$53,758,888 | $47.02 | 222 |
| 2023 Q1 | 52,951,870 | $2,221,541,781 | +$61,109,823 | $41.96 | 210 |
| 2022 Q4 | 51,655,406 | $1,969,597,318 | +$218,675 | $38.14 | 200 |
| 2022 Q3 | 51,490,290 | $2,016,420,954 | +$13,625,356 | $39.16 | 182 |
| 2022 Q2 | 51,071,239 | $1,649,759,751 | +$39,700,428 | $32.3 | 188 |
| 2022 Q1 | 49,945,298 | $1,653,434,346 | -$25,580,877 | $33.1 | 190 |
| 2021 Q4 | 50,185,286 | $2,135,089,557 | +$29,204,332 | $42.54 | 201 |
| 2021 Q3 | 49,060,569 | $2,173,846,483 | -$115,480,957 | $44.31 | 215 |
| 2021 Q2 | 50,613,429 | $2,875,212,413 | -$158,839,086 | $56.81 | 246 |
| 2021 Q1 | 53,088,674 | $3,974,807,423 | -$71,753,377 | $74.85 | 254 |
| 2020 Q4 | 53,803,776 | $4,654,671,800 | +$61,838,572 | $86.51 | 244 |
| 2020 Q3 | 53,660,582 | $3,277,403,116 | -$18,817,366 | $61.12 | 224 |
| 2020 Q2 | 54,023,562 | $2,247,849,991 | +$2,123,337 | $41.58 | 207 |
| 2020 Q1 | 55,020,519 | $1,580,165,244 | -$222,075,767 | $28.72 | 213 |
| 2019 Q4 | 55,964,444 | $4,040,118,901 | -$417,728,404 | $72.19 | 256 |
| 2019 Q3 | 58,267,547 | $8,175,198,734 | +$23,489,599 | $140.29 | 273 |
| 2019 Q2 | 58,089,604 | $10,632,783,890 | +$989,879,978 | $183.09 | 265 |
| 2019 Q1 | 56,290,569 | $8,953,438,249 | +$1,124,287,863 | $159.05 | 258 |
| 2018 Q4 | 49,737,058 | $4,761,682,266 | +$3,495,565 | $95.79 | 241 |
| 2018 Q3 | 49,008,712 | $6,924,204,711 | +$56,782,421 | $141.25 | 272 |
| 2018 Q2 | 48,621,395 | $7,610,500,125 | +$162,362,469 | $156.53 | 265 |
| 2018 Q1 | 47,521,631 | $7,647,354,047 | +$644,797,785 | $161.07 | 243 |
| 2017 Q4 | 44,056,451 | $7,257,119,465 | +$681,492,435 | $164.71 | 220 |
| 2017 Q3 | 39,314,584 | $2,450,400,062 | +$48,577,382 | $62.3 | 168 |
| 2017 Q2 | 38,446,334 | $3,055,447,026 | +$50,629,626 | $79.64 | 187 |
| 2017 Q1 | 37,871,607 | $2,691,023,691 | +$271,054,103 | $71.07 | 185 |
| 2016 Q4 | 36,733,208 | $1,875,786,404 | -$50,072,012 | $51.06 | 161 |
| 2016 Q3 | 37,761,752 | $1,738,397,667 | +$400,822,533 | $46.05 | 150 |
| 2016 Q2 | 30,208,087 | $911,383,018 | +$28,986,285 | $30.13 | 137 |
| 2016 Q1 | 29,073,553 | $931,907,546 | +$174,147,459 | $32.06 | 138 |
| 2015 Q4 | 23,473,499 | $1,368,495,352 | +$157,290,312 | $58.3 | 135 |
| 2015 Q3 | 27,212,732 | $1,151,636,509 | +$26,731,112 | $42.32 | 126 |
| 2015 Q2 | 26,411,389 | $1,927,998,498 | +$372,239,794 | $73 | 120 |
| 2015 Q1 | 21,505,189 | $1,080,202,161 | +$87,874,721 | $50.23 | 90 |
| 2014 Q4 | 19,746,808 | $722,803,309 | +$22,868,587 | $36.6 | 71 |
| 2014 Q3 | 18,894,149 | $595,167,000 | +$595,167,000 | $31.5 | 50 |