Latest Period
Q4 2025
Security Snapshot
GH Research PLC - Ordinary Shares, nominal value $0.025 per share (GHRS) Institutional Ownership
CUSIP: G3855L106
13F Institutional Holders and Ownership History from Q2 2021 to Q1 2026
Institutions Reporting
53
Shares (Excl. Options)
46,564,278
Price
$12.70
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- Type / Class
- Equity / Ordinary Shares, nominal value $0.025 per share
- Symbol
- GHRS on Nasdaq
- Shares outstanding
- 61,943,899
- Price per share
- $15.27
- All holders as of 31 Dec 2025
- Q4 2025
- Total 13F shares
- 46,564,278
- Total reported value
- $591,366,552
- % of total 13F portfolios
- 0%
- Share change
- +1,743,447
- Value change
- +$19,014,477
- Number of holders
- 53
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors
Quick Takeaways
- GHRS - GH Research PLC - Ordinary Shares, nominal value $0.025 per share is tracked under CUSIP G3855L106.
- 53 institutions reported positions in Q4 2025.
- 6 significant owners is listed from Schedule 13D/13G reporting.
What Changed
- Holder count moved from 53 to 13 between Q4 2025 and Q1 2026.
- Reported value moved from $591,366,552 to $171,640,186.
Why This Matters
- You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
- 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.
Source Evidence
Source: SEC Form 13F
Open SEC Evidence
Latest holder context comes from 53 institutions filings for Q4 2025.
Investment Quick Answers
What is CUSIP G3855L106?
CUSIP G3855L106 identifies GHRS - GH Research PLC - Ordinary Shares, nominal value $0.025 per share in SEC 13F datasets.
Where can I see the latest institutional holders?
Review the Q4 2025 holders report and the ownership history table below.
Next ownership checks
Use the next link that matches the question you still need to answer about this security.
- Latest 13F filings when you want to inspect fresh institutional portfolio moves.
- Latest Schedule 13D/13G reports when you need large-owner changes outside the 13F cycle.
- All institutional ownership pages to compare this security with other holder-history pages.
Recent Quarterly Holder Reports
Open recent reporting periods for CUSIP G3855L106:
Significant Owners of GH Research PLC - Ordinary Shares, nominal value $0.025 per share (GHRS) based on Schedule 13D/G filings
| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| Lynx1 Capital Management LP | 17% | +21% | $164,840,148 | +$28,597,314 | 10,406,575 | +21% | Lynx1 Capital Management LP | 31 Dec 2025 |
| BIOTECHNOLOGY VALUE FUND L P | 14% | $84,128,095 | 8,827,712 | BVF PARTNERS L P/IL | 31 Mar 2025 | |||
| RA CAPITAL MANAGEMENT, L.P. | 12% | +11% | $123,210,987 | +$11,749,386 | 7,676,697 | +11% | RA Capital Management, L.P. | 30 Jun 2025 |
| RTW INVESTMENTS, LP | 8.9% | $52,412,799 | 5,499,769 | RTW Investments, LP | 31 Mar 2025 | |||
| FMR LLC | 8.2% | +19% | $81,728,927 | +$13,523,168 | 5,092,145 | +20% | FMR LLC | 30 Jun 2025 |
| Terwey Theis H | 2.9% | -59% | $25,515,004 | -$41,593,509 | 1,784,266 | -62% | Terwey Theis H | 30 Sep 2025 |
As of 31 Dec 2025, 53 institutional investors reported holding 46,564,278 shares of GH Research PLC - Ordinary Shares, nominal value $0.025 per share (GHRS). This represents 75% of the company’s total 61,943,899 outstanding shares.
Top 25 Institutional Shareholders
The largest institutional shareholders of GH Research PLC - Ordinary Shares, nominal value $0.025 per share (GHRS) together control 75% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| Lynx1 Capital Management LP | 17% | 10,406,575 | +21% | 27% | $132,163,502 |
| BVF INC/IL | 14% | 8,827,712 | 0% | 3.8% | $112,111,942 |
| RA CAPITAL MANAGEMENT, L.P. | 12% | 7,676,697 | 0% | 1% | $97,494,052 |
| RTW INVESTMENTS, LP | 9.6% | 5,933,815 | +6.5% | 0.75% | $75,359,451 |
| FMR LLC | 8.3% | 5,136,045 | -3.6% | 0% | $65,227,771 |
| Avoro Capital Advisors LLC | 2.9% | 1,800,000 | 0.22% | $22,860,000 | |
| Cormorant Asset Management, LP | 2.1% | 1,300,000 | -32% | 0.94% | $16,510,000 |
| Jefferies Financial Group Inc. | 1.1% | 712,300 | +0.42% | 0.07% | $9,046,210 |
| Verition Fund Management LLC | 1.1% | 673,735 | -0.7% | 0.05% | $8,556,435 |
| 5AM Venture Management, LLC | 0.92% | 572,665 | 0% | 2.3% | $7,272,846 |
| BlackRock, Inc. | 0.7% | 434,401 | +651% | 0% | $5,516,893 |
| Troluce Capital Advisors LLC | 0.6% | 373,212 | +699% | 3.5% | $4,739,792 |
| UBS Group AG | 0.59% | 363,381 | -29% | 0% | $4,614,939 |
| Squadron Capital Management LLC | 0.51% | 315,000 | 0% | 1.8% | $4,000,500 |
| MILLENNIUM MANAGEMENT LLC | 0.48% | 295,926 | -66% | 0% | $3,758,260 |
| CenterBook Partners LP | 0.46% | 283,441 | +71% | 0.18% | $3,599,701 |
| MARSHALL WACE, LLP | 0.39% | 240,764 | +42% | 0% | $3,057,703 |
| HighVista Strategies LLC | 0.39% | 240,524 | -0.57% | 0.79% | $3,054,655 |
| Alyeska Investment Group, L.P. | 0.33% | 204,975 | 0% | 0.01% | $2,603,183 |
| BOOTHBAY FUND MANAGEMENT, LLC | 0.18% | 112,184 | +34% | 0.04% | $1,424,737 |
| GOLDMAN SACHS GROUP INC | 0.13% | 80,986 | +631% | 0% | $1,028,522 |
| AdvisorShares Investments LLC | 0.11% | 67,112 | +24% | 0.14% | $852,322 |
| Trexquant Investment LP | 0.09% | 54,776 | 0.01% | $695,655 | |
| MORGAN STANLEY | 0.08% | 51,404 | +1112% | 0% | $652,830 |
| JANE STREET GROUP, LLC | 0.08% | 50,005 | +117% | 0% | $635,063 |
Institutional Holders of GH Research PLC - Ordinary Shares, nominal value $0.025 per share (GHRS) across Reporting Periods
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2026 Q1 | 12,207,690 | $171,640,186 | +$4,613,669 | $14.06 | 13 |
| 2025 Q4 | 46,564,278 | $591,366,552 | +$19,014,477 | $12.70 | 53 |
| 2025 Q3 | 44,533,428 | $618,134,274 | +$14,411,795 | $14.30 | 47 |
| 2025 Q2 | 43,554,151 | $530,925,463 | +$12,435,267 | $12.19 | 37 |
| 2025 Q1 | 42,619,365 | $470,078,472 | +$132,646,472 | $11.03 | 35 |
| 2024 Q4 | 30,702,522 | $214,921,353 | +$703,147 | $7.00 | 31 |
| 2024 Q3 | 30,520,551 | $204,184,484 | +$470,359 | $6.69 | 28 |
| 2024 Q2 | 30,425,860 | $354,768,061 | +$9,911,656 | $11.66 | 28 |
| 2024 Q1 | 29,598,383 | $315,521,410 | +$9,696,487 | $10.66 | 32 |
| 2023 Q4 | 29,604,263 | $171,708,593 | +$1,756,706 | $5.80 | 35 |
| 2023 Q3 | 29,004,299 | $291,487,763 | -$8,205,765 | $10.05 | 29 |
| 2023 Q2 | 29,634,294 | $351,618,806 | -$693,689 | $11.86 | 34 |
| 2023 Q1 | 29,693,376 | $237,250,217 | -$9,782,816 | $7.99 | 29 |
| 2022 Q4 | 30,892,511 | $299,454,602 | -$7,759,406 | $9.72 | 32 |
| 2022 Q3 | 31,599,032 | $367,179,200 | -$9,454,337 | $11.62 | 33 |
| 2022 Q2 | 32,559,951 | $324,989,656 | +$3,737,200 | $9.98 | 33 |
| 2022 Q1 | 32,084,312 | $586,822,000 | +$37,199,278 | $18.29 | 30 |
| 2021 Q4 | 30,046,921 | $700,993,000 | +$26,953,821 | $23.33 | 29 |
| 2021 Q3 | 28,509,902 | $625,158,000 | +$21,272,275 | $22.06 | 29 |
| 2021 Q2 | 27,592,126 | $593,693,000 | +$593,693,000 | $21.73 | 34 |