GH Research PLC - Ordinary Shares, nominal value $0.025 per share (GHRS) Institutional Ownership

13F Institutional Holders and Ownership History from Q2 2021 to Q4 2025

Type / Class
Equity / Ordinary Shares, nominal value $0.025 per share
Symbol
GHRS on Nasdaq
Shares outstanding
61,943,899
Price per share
$16.24
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
46,564,278
Total reported value
$591,366,552
% of total 13F portfolios
0%
Share change
+1,743,447
Value change
+$19,014,477
Number of holders
53
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of GH Research PLC - Ordinary Shares, nominal value $0.025 per share (GHRS) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
Lynx1 Capital Management LP 17% +21% $164,840,148 +$28,597,314 10,406,575 +21% Lynx1 Capital Management LP 31 Dec 2025
BIOTECHNOLOGY VALUE FUND L P 14% $84,128,095 8,827,712 BVF PARTNERS L P/IL 31 Mar 2025
RA CAPITAL MANAGEMENT, L.P. 12% +11% $123,210,987 +$11,749,386 7,676,697 +11% RA Capital Management, L.P. 30 Jun 2025
RTW INVESTMENTS, LP 8.9% $52,412,799 5,499,769 RTW Investments, LP 31 Mar 2025
FMR LLC 8.2% +19% $81,728,927 +$13,523,168 5,092,145 +20% FMR LLC 30 Jun 2025
Terwey Theis H 2.9% -59% $25,515,004 -$41,593,509 1,784,266 -62% Terwey Theis H 30 Sep 2025

As of 31 Dec 2025, 53 institutional investors reported holding 46,564,278 shares of GH Research PLC - Ordinary Shares, nominal value $0.025 per share (GHRS). This represents 75% of the company’s total 61,943,899 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of GH Research PLC - Ordinary Shares, nominal value $0.025 per share (GHRS) together control 75% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
Lynx1 Capital Management LP 17% 10,406,575 +21% 27% $132,163,502
BVF INC/IL 14% 8,827,712 0% 3.8% $112,111,942
RA CAPITAL MANAGEMENT, L.P. 12% 7,676,697 0% 1% $97,494,052
RTW INVESTMENTS, LP 9.6% 5,933,815 +6.5% 0.75% $75,359,451
FMR LLC 8.3% 5,136,045 -3.6% 0% $65,227,771
Avoro Capital Advisors LLC 2.9% 1,800,000 0.23% $22,860,000
Cormorant Asset Management, LP 2.1% 1,300,000 -32% 0.94% $16,510,000
Jefferies Financial Group Inc. 1.1% 712,300 +0.42% 0.07% $9,046,210
Verition Fund Management LLC 1.1% 673,735 -0.7% 0.05% $8,556,435
5AM Venture Management, LLC 0.92% 572,665 0% 2.3% $7,272,846
BlackRock, Inc. 0.7% 434,401 +651% 0% $5,516,893
Troluce Capital Advisors LLC 0.6% 373,212 +699% 3.5% $4,739,792
UBS Group AG 0.59% 363,381 -29% 0% $4,614,939
Squadron Capital Management LLC 0.51% 315,000 0% 1.8% $4,000,500
MILLENNIUM MANAGEMENT LLC 0.48% 295,926 -66% 0% $3,758,260
CenterBook Partners LP 0.46% 283,441 +71% 0.18% $3,599,701
MARSHALL WACE, LLP 0.39% 240,764 +42% 0% $3,057,703
HighVista Strategies LLC 0.39% 240,524 -0.57% 0.79% $3,054,655
Alyeska Investment Group, L.P. 0.33% 204,975 0% 0.01% $2,603,183
BOOTHBAY FUND MANAGEMENT, LLC 0.18% 112,184 +34% 0.04% $1,424,737
GOLDMAN SACHS GROUP INC 0.13% 80,986 +631% 0% $1,028,522
AdvisorShares Investments LLC 0.11% 67,112 +24% 0.14% $852,322
Trexquant Investment LP 0.09% 54,776 0.01% $695,655
MORGAN STANLEY 0.08% 51,404 +1112% 0% $652,830
JANE STREET GROUP, LLC 0.08% 50,005 +117% 0% $635,063

Institutional Holders of GH Research PLC - Ordinary Shares, nominal value $0.025 per share (GHRS) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 46,564,278 $591,366,552 +$19,014,477 $12.70 53
2025 Q3 44,533,428 $618,134,274 +$14,411,795 $14.30 47
2025 Q2 43,554,151 $530,925,463 +$12,435,267 $12.19 37
2025 Q1 42,619,365 $470,078,472 +$132,646,472 $11.03 35
2024 Q4 30,702,522 $214,921,353 +$703,147 $7.00 31
2024 Q3 30,520,551 $204,184,484 +$470,359 $6.69 28
2024 Q2 30,425,860 $354,768,061 +$9,911,656 $11.66 28
2024 Q1 29,598,383 $315,521,410 +$9,696,487 $10.66 32
2023 Q4 29,604,263 $171,708,593 +$1,756,706 $5.80 35
2023 Q3 29,004,299 $291,487,763 -$8,205,765 $10.05 29
2023 Q2 29,634,294 $351,618,806 -$693,689 $11.86 34
2023 Q1 29,693,376 $237,250,217 -$9,782,816 $7.99 29
2022 Q4 30,892,511 $299,454,602 -$7,759,406 $9.72 32
2022 Q3 31,599,032 $367,179,200 -$9,454,337 $11.62 33
2022 Q2 32,559,951 $324,989,656 +$3,737,200 $9.98 33
2022 Q1 32,084,312 $586,822,000 +$37,199,278 $18.29 30
2021 Q4 30,046,921 $700,993,000 +$26,953,821 $23.33 29
2021 Q3 28,509,902 $625,158,000 +$21,272,275 $22.06 29
2021 Q2 27,592,126 $593,693,000 +$593,693,000 $21.73 34