Significant Ownership of PERCEPTIVE ADVISORS LLC

Signature - Title
/s/ Joseph Edelman - Joseph Edelman, Managing Member
Location
New York, NY
Summary
This page shows a list of all the recent SCHEDULE 13D/G filings made by PERCEPTIVE ADVISORS LLC.

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Significant Ownership of PERCEPTIVE ADVISORS LLC

Sym Company Class Ownership Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
ADGM Adagio Medical Holdings, Inc. Common Stock, $0.0001 par value per share 73.6% $18,385,986 15,321,655 Perceptive Advisors LLC 31 Dec 2024
ATHA Athira Pharma, Inc. Common Stock, $0.0001 par value 20.1% $8,074,296 $5,698,192 1,869,050 +2.4% Joseph Edelman 23 Dec 2025
SLDB Solid Biosciences Inc. Common Stock, $0.001 par value per share 15.6% $43,800,272 11,934,679 Perceptive Advisors LLC 19 Feb 2025
LYRA Lyra Therapeutics, Inc. Common Stock, $0.001 par value 15.55% $22,174 255,750 Perceptive Advisors LLC 12 Aug 2025
ATXS Astria Therapeutics, Inc. Common Stock, par value $0.001 per share 11.5% $47,213,858 6,485,420 Perceptive Advisors LLC 14 Oct 2025
NAUT Nautilus Biotechnology, Inc. Common Stock, $0.0001 par value per share 10.1% $11,149,148 $192,184 12,815,113 +1.8% Perceptive Advisors LLC 20 Jun 2025
ENGN enGene Holdings Inc. Common Shares 9.99% $47,123,411 6,770,605 Perceptive Advisors LLC 11 Nov 2025
OBIO Orchestra BioMed Holdings, Inc. Common Stock, par value $0.0001 per share 9.99% $14,085,110 5,679,480 Perceptive Advisors LLC 30 Sep 2025
PALI PALISADE BIO, INC. Common Stock, $0.01 par value 9.99% $7,100,950 12,243,018 Perceptive Advisors LLC 02 Oct 2025
IRD Opus Genetics, Inc. Common Stock, $0.0001 par value per share 9.99% $3,608,401 4,510,501 Perceptive Advisors LLC 24 Mar 2025
TRAW Traws Pharma, Inc. Common Stock, par value $0.01 per share 9.99% $1,641,628 $632,468 886,887 +62.7% Perceptive Advisors LLC 30 Sep 2025
TRIB Trinity Biotech plc Class A Ordinary Shares, $0.0001 par value per share 9.9% $1,468,881,086 $1,370,097,085 1,498,858,251 +13.9% Perceptive Advisors LLC 22 Dec 2025
OM Outset Medical, Inc. Common Stock, $0.001 par value per share 9.5% $32,688,000 5,625,000 Perceptive Advisors LLC 08 Jan 2025
ALDX Aldeyra Therapeutics, Inc. Common Stock, par value $0.001 per share 8.7% $27,260,463 $6,110,949 5,222,311 +28.9% Perceptive Advisors LLC 30 Sep 2025
AMLX Amylyx Pharmaceuticals, Inc. Common Stock, $0.0001 par value per share 8.2% $121,662,640 $14,650,251 8,952,365 +13.7% Perceptive Advisors LLC 30 Sep 2025
IVVD INVIVYD, INC. Common Stock, $0.0001 par value per share 7.9% $40,738,260 21,785,166 Perceptive Advisors LLC 18 Nov 2025
XFOR X4 PHARMACEUTICALS, INC. Common Stock, par value $0.001 per share 7.6% $20,980,760 6,064,680 Perceptive Advisors LLC 27 Oct 2025
ANRO Alto Neuroscience, Inc. Common Stock, $0.0001 par value per share 7.3% $7,718,845 1,989,393 Perceptive Advisors LLC 03 Oct 2025
TENX Tenax Therapeutics, Inc. Common Stock, $0.0001 par value per share 7% $4,158,675 439,142 Perceptive Advisors LLC 18 Dec 2025
RYTM Rhythm Pharmaceuticals, Inc. Common Stock, $0.001 par value per share 6.8% $284,913,835 4,423,441 Perceptive Advisors LLC 31 Mar 2025
OM Outset Medical, Inc. Common Stock, $0.001 par value per share 6.7% $14,028,758 1,208,334 Perceptive Advisors LLC 31 Mar 2025
PRAX Praxis Precision Medicines, Inc. Common Stock, par value $0.0001 per share 6.69% $57,294,886 $16,047,116 1,362,503 +38.9% Perceptive Advisors LLC 15 Jul 2025
CELC Celcuity Inc. Common Stock, $0.001 par value per share 6.55% $35,625,764 $13,838,769 2,670,597 +63.5% Perceptive Advisors LLC 30 Jul 2025
DRUG Bright Minds Biosciences Inc. Common Shares, without par value 6.3% $13,735,208 444,649 Perceptive Advisors LLC 31 Mar 2025
CTMX CytomX Therapeutics, Inc. Common Stock, $0.00001 par value per share 5.9% $22,458,029 9,680,185 Perceptive Advisors LLC 14 Aug 2025
TVTX TRAVERE THERAPEUTICS, INC. Common Stock, par value $0.0001 per share 5.5% $117,005,198 4,895,615 Perceptive Advisors LLC 06 Oct 2025
BDSX Biodesix, Inc. Common Stock, par value $0.001 per share 5.1% $4,374,112 $570,000 7,673,880 +15% Perceptive Advisors LLC 12 May 2025
IVA Inventiva S.A. Ordinary shares, nominal value euro 0.01 per share 4.99% $42,246,764 $10,098,433 7,300,666 +31.4% Perceptive Advisors LLC 30 Sep 2025
AVR Anteris Technologies Global Corp. Common Stock, par value $0.0001 per share 4.7% $5,933,852 -$2,557,347 1,705,130 -30.1% Perceptive Advisors LLC 30 Jun 2025
ACLX Arcellx, Inc. Common Stock, par value $0.001 per share 4.5% $162,432,900 -$29,397,732 2,478,000 -15.3% Perceptive Advisors LLC 30 Jun 2025
RAPT RAPT Therapeutics, Inc. Common Stock, $0.0001 par value per share 4.5% $5,115,600 5,880,000 Perceptive Advisors LLC 31 Dec 2024
EWTX Edgewise Therapeutics, Inc. Common Stock, par value $0.0001 per share 4.4% $60,458,535 -$22,875,428 4,639,949 -27.5% Perceptive Advisors LLC 30 Jun 2025
SYRE Spyre Therapeutics, Inc. Common Stock, $0.0001 par value per share 4.4% $38,672,339 -$185,961,697 2,574,723 -79.6% Perceptive Advisors LLC 31 Dec 2024
AORT ARTIVION, INC. Common Stock, $0.01 par value 4.3% $85,526,800 2,020,000 Perceptive Advisors LLC 30 Sep 2025
IOVA Iovance Biotherapeutics, Inc. Common Stock, par value $0.000041666 per share 3.8% $45,599,285 -$33,120,381 12,808,788 -42.1% Perceptive Advisors LLC 31 Mar 2025
EOLS Evolus, Inc. Common Stock, $0.00001 par value per share 3.8% $23,461,512 -$15,682,754 2,474,843 -40.1% Perceptive Advisors LLC 30 Jun 2025
ENSC Ensysce Biosciences, Inc. Common Stock, par value $0.0001 per share 3.7% $264,331 86,666 0% Perceptive Advisors LLC 31 Mar 2025
BBNX Beta Bionics, Inc. Common Stock, $0.0001 par value per share 3.68% $21,609,324 1,593,608 Perceptive Advisors LLC 31 Mar 2025
CTNM Contineum Therapeutics, Inc. Class A Common Stock, par value $0.001 per share 3.2% $2,776,959 -$2,944,799 699,486 -51.5% Perceptive Advisors LLC 30 Jun 2025
CRGX CARGO Therapeutics, Inc. Common Stock, $0.001 par value per share 2.5% $5,420,850 1,170,810 Perceptive Advisors LLC 23 Apr 2025
FBRX Forte Biosciences, Inc. Common Stock, par value $0.001 per share 2.5% $1,209,840 163,935 Perceptive Advisors LLC 31 Dec 2024
FOLD Amicus Therapeutics, Inc. Common Stock, par value $0.01 per share 2.4% $43,290,927 -$82,061,910 7,412,830 -65.5% Perceptive Advisors LLC 30 Jun 2025
APLT Applied Therapeutics, Inc. Common Stock, $0.0001 par value per share 2.4% $1,115,400 2,860,000 Perceptive Advisors LLC 31 Dec 2024
SRZN Surrozen, Inc. Common Stock, $0.0001 par value per share 1.9% $1,669,993 166,666 0% Perceptive Advisors LLC 31 Mar 2025
VRCA Verrica Pharmaceuticals, Inc. Common Stock, $0.0001 par value per share 1.6% $725,926 -$1,592,337 1,481,481 -68.7% Perceptive Advisors LLC 31 Mar 2025
KALA KALA BIO, Inc. Common Stock, par value $0.001 per share 0% $0 -$831,712 0 -100% Perceptive Advisors LLC 30 Sep 2025
ACRV Acrivon Therapeutics, Inc. Common Stock, par value $0.001 per share 0% $0 -$3,600,801 0 -100% Perceptive Advisors LLC 02 Jun 2025
TIL Instil Bio, Inc. Common Stock, par value $0.000001 per share 0% $0 0 Perceptive Advisors LLC 31 Mar 2025
LYRA Lyra Therapeutics, Inc. Common Stock, $0.001 par value 0% $0 -$595,704 0 -100% Perceptive Advisors LLC 21 Nov 2025
VRNA Verona Pharma plc Ordinary shares, nominal value GBP 0.05 per share 0% $0 -$587,715,035 0 -100% Perceptive Advisors LLC 30 Sep 2025
OKUR OnKure Therapeutics, Inc. Common Stock, par value $0.0001 per share $0 0 Perceptive Advisors LLC 30 Jun 2025

Schedules 13D/G Reported by PERCEPTIVE ADVISORS LLC:

Sym Target Class Ownership Change Current Shares Change Value Reporting name Form Report Period Filing Date
* An asterisk sign (*) next to the price indicates that the price is likely invalid.