Significant Ownership of PERCEPTIVE ADVISORS LLC

Large-stake snapshot 1 signal
Large-stake filing summary
  • Recent SEC Schedule 13D/G filings for PERCEPTIVE ADVISORS LLC focus on large-stake beneficial ownership disclosures and amendments.
  • Use this view to spot new large holders, amended positions, and activist-style ownership evidence.
Manager Names, identifiers, and filing context for this profile. 2 identity fields
Manager signature
/s/ Joseph Edelman - Joseph Edelman, Managing Member
Manager location
New York, NY

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Significant Ownership of PERCEPTIVE ADVISORS LLC

Sym Company Class Ownership Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
ADGM Adagio Medical Holdings, Inc. Common Stock, par value $0.0001 per share 55% $19,611,718 15,321,655 0% Perceptive Advisors LLC 31 Mar 2026
LONA LeonaBio, Inc. Common Stock, $0.0001 par value 20% $17,987,117 +$286,371 1,889,403 +1.6% Perceptive Advisors LLC 22 Aug 2026
ATHA LeonaBio, Inc. Common Stock, $0.0001 par value 20% $715,301 1,882,370 Perceptive Advisors LLC 05 May 2026
LYRA Lyra Therapeutics, Inc. Common Stock, $0.001 par value 16% $22,174 255,750 Perceptive Advisors LLC 12 Aug 2025
MGTX MeiraGTx Holdings plc Ordinary Shares, nominal value $0.00003881 per share 13% $101,691,430 +$11,263,327 11,742,117 +12% Perceptive Advisors LLC 17 Apr 2026
SLDB Solid Biosciences Inc. Common Stock, $0.001 par value per share 11% $117,092,748 +$753,300 12,046,579 +0.65% Perceptive Advisors LLC 30 Jun 2026
Freenome, Inc. Common Stock, par value $0.0001 per share 10% 10,871,847 Perceptive Advisors LLC 20 Jul 2026
INBX INHIBRX BIOSCIENCES, INC. Common Stock, par value $0.0001 10% $144,624,915 +$2,751,620 1,489,443 +1.9% Perceptive Advisors LLC 30 Jun 2026
ANRO Alto Neuroscience, Inc. Common Stock, $0.0001 par value per share 10% $107,341,473 +$23,818,169 4,176,711 +29% Perceptive Advisors LLC 30 Jun 2026
IRD Opus Genetics, Inc. Common Stock, $0.0001 par value per share 10% $37,858,211 +$1,654,616 9,233,710 +4.6% Perceptive Advisors LLC 30 Jun 2026
PALI PALISADE BIO, INC. Common Stock, $0.01 par value 10% $29,184,225 +$5,677,630 15,200,117 +24% Perceptive Advisors LLC 31 Dec 2025
OBIO Orchestra BioMed Holdings, Inc. Common Stock, par value $0.0001 per share 10% $14,085,110 5,679,480 Perceptive Advisors LLC 30 Sep 2025
ENGN enGene Holdings Inc. Common Shares 10% $11,936,659 +$223,513 6,899,803 +1.9% Perceptive Advisors LLC 30 Jun 2026
KPRX KIORA PHARMACEUTICALS, INC. Common Stock, $0.01 par value 10% $1,163,434 442,387 Perceptive Advisors LLC 06 Apr 2026
NVNO enVVeno Medical Corporation Common Stock, $0.00001 par value 10% $23,298 -$673,197 68,525 -97% Perceptive Advisors LLC 31 Mar 2026
Yarrow Bioscience, Inc. Common Stock, $0.0001 par value 10% 266,756 Perceptive Advisors LLC 27 Jul 2026
TRIB Trinity Biotech plc Class A Ordinary Shares, $0.0001 par value per share 9.9% $2,431,054,169 +$1,392,282,813 3,424,019,957 +134% Perceptive Advisors LLC 30 Apr 2026
OM Outset Medical, Inc. Common Stock, $0.001 par value per share 9.5% $32,688,000 5,625,000 Perceptive Advisors LLC 08 Jan 2025
NAUT Nautilus Biotechnology, Inc. Common Stock, par value $0.0001 per share 9.1% $21,755,975 -$2,208,287 11,634,211 -9.2% Perceptive Advisors LLC 30 Jun 2026
Kardigan, Inc. Common Stock, par value $0.00001 per share 8.9% 8,254,144 Perceptive Advisors LLC 18 Jun 2026
Research Alliance Corporation III Class A Ordinary Shares, par value $0.0001 per share 8.2% 750,000 Perceptive Advisors LLC 20 May 2026
XFOR X4 PHARMACEUTICALS, INC. Common Stock, par value $0.001 per share 8.1% $35,654,876 +$8,909,638 8,085,006 +33% Perceptive Advisors LLC 30 Jun 2026
STRO SUTRO BIOPHARMA, INC. Common stock, $0.001 par value 7.9% $39,967,433 1,304,846 Perceptive Advisors LLC 30 Jun 2026
IMVIQ PALISADE BIO, INC. Common Stock, $0.01 par value 7.9% 14,113,863 Perceptive Advisors LLC 31 Mar 2026
Research Alliance Corporation IV Class A Ordinary Shares, par value $0.0001 per share 7.7% 700,000 Perceptive Advisors LLC 13 Jul 2026
IMTX Immatics N.V. Ordinary Shares, nominal value EUR 0.01 per share 7.6% $102,647,964 11,418,016 Perceptive Advisors LLC 26 Aug 2026
AMLX Amylyx Pharmaceuticals, Inc. Common Stock, $0.0001 par value per share 7.5% $136,452,007 -$10,993,445 8,284,882 -7.5% Perceptive Advisors LLC 31 Mar 2026
SABS SAB BIOTHERAPEUTICS, INC. Common Stock, $0.0001 par value per share 7.3% $26,244,904 +$775,202 6,627,501 +3% Perceptive Advisors LLC 30 Jun 2026
XFOR X4 PHARMACEUTICALS, INC. Common Stock, par value $0.001 per share 7.3% $1,308,941 6,889,163 Perceptive Advisors LLC 31 Mar 2026
PRAX Praxis Precision Medicines, Inc. Common Stock, par value $0.0001 per share 7.2% $575,742,162 +$182,728,171 1,995,986 +46% Perceptive Advisors LLC 31 Dec 2025
IKT INHIBIKASE THERAPEUTICS, INC. Common Stock, $0.001 par value 6.9% $21,054,585 -$4,722,600 10,320,875 -18% Perceptive Advisors LLC 30 Jun 2026
CELC Celcuity Inc. Common Stock, $0.001 par value per share 6.8% $329,324,442 +$51,021,529 3,160,200 +18% Perceptive Advisors LLC 31 Dec 2025
OM Outset Medical, Inc. Common Stock, $0.001 par value per share 6.7% $14,028,758 1,208,334 Perceptive Advisors LLC 31 Mar 2025
EDSA EDESA BIOTECH, INC. Common Shares, without par value 6.7% $551,974 563,239 Perceptive Advisors LLC 09 Mar 2026
RLAY RELAY THERAPEUTICS, INC. Common Stock, par value $0.001 per share 6.4% $264,208,883 +$255,996,321 14,106,187 +3117% Perceptive Advisors LLC 30 Jun 2026
IVVD INVIVYD, INC. Common Stock, $0.0001 par value per share 6.3% $14,792,509 -$2,635,624 18,490,636 -15% Perceptive Advisors LLC 30 Jun 2026
TRAW Traws Pharma, Inc. Common Stock, par value $0.01 per share 6.1% $1,793,061 +$170,058 979,815 +10% Perceptive Advisors LLC 31 Mar 2026
BlossomHill Therapeutics, Inc. Common Stock, par value $0.0001 5.9% 1,808,533 Perceptive Advisors LLC 07 Aug 2026
ZYME ZYMEWORKS INC. Common Stock, $0.00001 par value per share 5.4% $99,527,035 3,974,579 Perceptive Advisors LLC 08 Apr 2026
STRO SUTRO BIOPHARMA, INC. Common stock, $0.001 par value 5.4% $22,370,431 898,025 Perceptive Advisors LLC 14 Apr 2026
RYTM RHYTHM PHARMACEUTICALS, INC. Common Stock, $0.001 par value per share 5.1% $303,708,528 -$77,990,196 3,519,626 -20% Perceptive Advisors LLC 31 Mar 2026
IVA Inventiva S.A. Ordinary shares, nominal value euro 0.01 per share 5% $42,246,764 +$10,098,434 7,300,666 +31% Perceptive Advisors LLC 30 Sep 2025
SYRE SPYRE THERAPEUTICS, INC. Common Stock, $0.0001 Par Value Per Share 4.9% $383,312,075 4,319,496 0% Perceptive Advisors LLC 30 Jun 2026
TVTX TRAVERE THERAPEUTICS, INC. Common Stock, par value $0.0001 per share 4.8% $124,537,820 -$17,973,533 4,278,180 -13% Perceptive Advisors LLC 31 Dec 2025
AVR Anteris Technologies Global Corp. Common Stock, par value $0.0001 per share 4.7% $5,933,852 -$2,557,348 1,705,130 -30% Perceptive Advisors LLC 30 Jun 2025
CTMX CytomX Therapeutics, Inc. Common Stock, $0.00001 par value per share 4.6% $43,424,943 +$1,800,148 10,098,824 +4.3% Perceptive Advisors LLC 31 Mar 2026
DRUG Bright Minds Biosciences Inc. Common Shares, without par value 4.6% $40,171,019 +$414,952 449,290 +1% Perceptive Advisors LLC 31 Dec 2025
BDSX BIODESIX, INC. Common Stock, $0.001 par value per share 4.6% $3,289,119 -$48,893,265 483,694 -94% Perceptive Advisors LLC 31 Mar 2026
ACLX Arcellx, Inc. Common Stock, par value $0.001 per share 4.5% $162,432,900 -$29,397,733 2,478,000 -15% Perceptive Advisors LLC 30 Jun 2025
TENX Tenax Therapeutics, Inc. Common Stock, $0.0001 par value per share 4.5% $27,166,000 +$4,030,444 1,700,000 +17% Perceptive Advisors LLC 30 Jun 2026
RAPT RAPT Therapeutics, Inc. Common Stock, $0.0001 par value per share 4.5% $5,115,600 5,880,000 Perceptive Advisors LLC 31 Dec 2024
EWTX Edgewise Therapeutics, Inc. Common Stock, par value $0.0001 per share 4.4% $60,458,535 -$22,875,429 4,639,949 -27% Perceptive Advisors LLC 30 Jun 2025
AORT ARTIVION, INC. Common Stock, $0.01 par value 4.3% $85,526,800 2,020,000 Perceptive Advisors LLC 30 Sep 2025
IOVA Iovance Biotherapeutics, Inc. Common Stock, par value $0.000041666 per share 3.8% $45,599,285 -$33,120,382 12,808,788 -42% Perceptive Advisors LLC 31 Mar 2025
EOLS Evolus, Inc. Common Stock, $0.00001 par value per share 3.8% $23,461,512 -$15,682,755 2,474,843 -40% Perceptive Advisors LLC 30 Jun 2025
ENSC Ensysce Biosciences, Inc. Common Stock, par value $0.0001 per share 3.7% $264,331 86,666 0% Perceptive Advisors LLC 31 Mar 2025
BBNX Beta Bionics, Inc. Common Stock, $0.0001 par value per share 3.7% $21,609,324 1,593,608 Perceptive Advisors LLC 31 Mar 2025
NVNO enVVeno Medical Corporation Common Stock, $0.00001 par value 3.5% $263,766 24,605 Perceptive Advisors LLC 30 Jun 2026
CTNM Contineum Therapeutics, Inc. Class A Common Stock, par value $0.001 per share 3.2% $2,776,959 -$2,944,799 699,486 -51% Perceptive Advisors LLC 30 Jun 2025
CRGX CARGO Therapeutics, Inc. Common Stock, $0.001 par value per share 2.5% $5,420,850 1,170,810 Perceptive Advisors LLC 23 Apr 2025
FBRX Forte Biosciences, Inc. Common Stock, par value $0.001 per share 2.5% $1,209,840 163,935 Perceptive Advisors LLC 31 Dec 2024
FOLD Amicus Therapeutics, Inc. Common Stock, par value $0.01 per share 2.4% $43,290,927 -$82,061,910 7,412,830 -65% Perceptive Advisors LLC 30 Jun 2025
APLT Applied Therapeutics, Inc. Common Stock, $0.0001 par value per share 2.4% $1,115,400 2,860,000 Perceptive Advisors LLC 31 Dec 2024
SRZN Surrozen, Inc. Common Stock, $0.0001 par value per share 1.9% $1,669,993 166,666 0% Perceptive Advisors LLC 31 Mar 2025
VRCA Verrica Pharmaceuticals, Inc. Common Stock, $0.0001 par value per share 1.6% $725,926 -$1,592,338 1,481,481 -69% Perceptive Advisors LLC 31 Mar 2025
VRNA Verona Pharma plc Ordinary shares, nominal value GBP 0.05 per share 0% $0 -$587,715,036 0 -100% Perceptive Advisors LLC 30 Sep 2025
LYRA Lyra Therapeutics, Inc. Common Stock, $0.001 par value 0% $0 -$595,704 0 -100% Perceptive Advisors LLC 21 Nov 2025
KALA KALA BIO, Inc. Common Stock, par value $0.001 per share 0% $0 -$831,712 0 -100% Perceptive Advisors LLC 30 Sep 2025
TIL Instil Bio, Inc. Common Stock, par value $0.000001 per share 0% $0 0 Perceptive Advisors LLC 31 Mar 2025
ATXS Astria Therapeutics, Inc. Common Stock, par value $0.001 per share 0% $0 -$82,494,542 0 -100% Perceptive Advisors LLC 26 Jan 2026
ALDX Aldeyra Therapeutics, Inc. Common Stock, par value $0.001 per share 0% $0 -$6,362,161 0 -100% Perceptive Advisors LLC 31 Mar 2026
ACRV Acrivon Therapeutics, Inc. Common Stock, par value $0.001 per share 0% $0 -$3,600,801 0 -100% Perceptive Advisors LLC 02 Jun 2025
OKUR OnKure Therapeutics, Inc. Common Stock, par value $0.0001 per share $0 0 Perceptive Advisors LLC 30 Jun 2025

Schedules 13D/G Reported by PERCEPTIVE ADVISORS LLC:

Sym Target Class Ownership Change Current shares Change Value Reporting name Form Report period Filing date
Schedule rows are parsed from SEC 13D/G filings. Open the linked filing or target page to verify the reported ownership and shares.
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