Security Snapshot

Opus Genetics, Inc. - Common Stock, $0.0001 par value per share (IRD) Institutional Ownership

CUSIP: 67577R102

13F Institutional Holders and Ownership History from Q4 2020 to Q1 2026

Latest Period

Q1 2026

Institutions Reporting

76

Shares (Excl. Options)

44,276,162

Price

$4.55

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Type / Class
Equity / Common Stock, $0.0001 par value per share
Symbol
IRD on Nasdaq
Shares outstanding
81,377,060
Price per share
$4.67
All holders as of 31 Mar 2026
Q1 2026
Total 13F shares
44,276,162
Total reported value
$201,458,238
% of total 13F portfolios
0%
Share change
+17,181,341
Value change
+$79,524,140
Number of holders
76
Price from insider filings
$4.67
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Key facts

  • IRD - Opus Genetics, Inc. - Common Stock, $0.0001 par value per share is tracked under CUSIP 67577R102.
  • 76 institutions reported positions in Q1 2026.
  • 7 significant owners is listed from Schedule 13D/13G reporting.

Change

  • Holder count moved from 58 to 76 between Q4 2025 and Q1 2026.
  • Reported value moved from $55,903,061 to $201,458,238.

Research use

  • You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
  • 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.

Evidence

Source: SEC Form 13F

Latest holder context comes from 76 institutions filings for Q1 2026.

Open SEC Evidence

Security key

67577R102

Latest holder period

Q1 2026

13F holders

76

13D/G owners

7

CIK / CUSIP context first

Significant Owners of Opus Genetics, Inc. - Common Stock, $0.0001 par value per share (IRD) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
PERCEPTIVE ADVISORS LLC 10% 0% $43,444,313 +$8,147,476 8,830,145 +23% Perceptive Advisors LLC 31 Mar 2026
Caligan Partners LP 8.5% $29,889,138 6,075,028 Caligan Partners LP 31 Mar 2026
Adage Capital Management, L.P. 8.5% $29,666,493 6,029,775 Adage Capital Management, L.P. 31 Mar 2026
BALYASNY ASSET MANAGEMENT L.P. 7.2% -3.3% $25,143,035 5,110,373 0% Balyasny Asset Management L.P. 31 Mar 2026
Nantahala Capital Management, LLC 6.5% -35% $23,808,987 -$11,238,663 4,839,225 -32% Nantahala Capital Management, LLC 31 Mar 2026
Foundation Fighting Blindness Retinal Degeneration Fund 4.7% -42% $17,709,439 -$7,939,000 3,792,171 -31% Foundation Fighting Blindness Retinal Degeneration Fund 18 May 2026
BIOS Fund III, LP 4.5% $18,122,471 3,683,429 AARON G.L. FLETCHER 12 May 2026

As of 31 Mar 2026, 76 institutional investors reported holding 44,276,162 shares of Opus Genetics, Inc. - Common Stock, $0.0001 par value per share (IRD). This represents 54% of the company’s total 81,377,060 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of Opus Genetics, Inc. - Common Stock, $0.0001 par value per share (IRD) together control 52% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
Caligan Partners LP 7.5% 6,075,028 2% $27,641,377
ADAGE CAPITAL PARTNERS GP, L.L.C. 7.4% 6,029,775 +446% 0.04% $27,435,476
BIOS Capital Management, LP 4.5% 3,683,429 0% 32% $16,759,602
Balyasny Asset Management L.P. 3.3% 2,718,029 0% 0.02% $12,367,032
MILLENNIUM MANAGEMENT LLC 3.2% 2,630,432 +31% 0.01% $11,968,466
VANGUARD CAPITAL MANAGEMENT LLC 3% 2,449,987 0% 0% $11,147,441
MARSHALL WACE, LLP 2.8% 2,313,380 +1367% 0.01% $10,525,879
Boxer Capital Management, LLC 2.8% 2,250,000 1.3% $10,237,500
ADAR1 Capital Management, LLC 2.3% 1,849,004 +4523% 0.51% $8,412,968
PERCEPTIVE ADVISORS LLC 2.3% 1,835,842 -58% 0.17% $8,353,081
Nantahala Capital Management, LLC 2.1% 1,681,330 -65% 0.48% $7,650,052
Woodline Partners LP 1.7% 1,354,030 0.02% $6,160,837
BOOTHBAY FUND MANAGEMENT, LLC 1.5% 1,189,113 0.13% $5,410,464
FARALLON CAPITAL MANAGEMENT LLC 1.2% 1,000,000 0.03% $4,550,000
SUSQUEHANNA INTERNATIONAL GROUP, LLP 1% 823,383 +308% 0% $3,746,393
Bleichroeder LP 0.91% 736,842 0% 0.58% $3,352,631
Mink Brook Asset Management LLC 0.73% 590,552 -65% 1.5% $2,687,012
GEODE CAPITAL MANAGEMENT, LLC 0.66% 538,347 +6.6% 0% $2,451,169
Trails Edge Capital Partners, LP 0.61% 500,000 0.54% $2,275,000
AMERIPRISE FINANCIAL INC 0.48% 388,491 0% $1,767,634
GOLDMAN SACHS GROUP INC 0.4% 326,809 0% $1,486,981
GREAT POINT PARTNERS LLC 0.4% 324,340 0.36% $1,475,747
VANGUARD FIDUCIARY TRUST CO 0.35% 281,801 0% 0% $1,282,195
UBS Group AG 0.32% 257,649 +187% 0% $1,172,303
STATE STREET CORP 0.25% 199,953 +15% 0% $909,786

Institutional Holders of Opus Genetics, Inc. - Common Stock, $0.0001 par value per share (IRD) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2026 Q1 44,276,162 $201,458,238 +$79,524,140 $4.55 76
2025 Q4 27,812,069 $55,903,061 +$17,653,005 $2.01 58
2025 Q3 19,026,274 $31,911,867 +$2,765,658 $1.65 46
2025 Q2 17,503,196 $16,482,508 +$2,741,389 $0.94 43
2025 Q1 14,560,311 $14,686,745 +$11,049,669 $0.98 46
2024 Q4 3,678,848 $4,378,207 +$106,956 $1.19 42
2024 Q3 2,531,596 $3,315,513 -$283,780 $1.31 37
2024 Q2 2,696,097 $4,126,103 -$1,250,857 $1.53 37
2024 Q1 3,374,307 $6,780,798 -$925,460 $2.01 48
2023 Q4 3,712,141 $11,173,334 -$177,249 $3.01 48
2023 Q3 3,768,545 $12,624,748 +$43,437 $3.35 50
2023 Q2 3,675,838 $15,952,413 +$1,001,477 $4.34 49
2023 Q1 3,457,077 $12,962,551 +$1,457,390 $3.75 40
2022 Q4 3,099,588 $10,946,085 +$1,241,957 $3.53 34
2022 Q3 2,825,667 $5,686,000 +$828,901 $2.01 33
2022 Q2 2,407,242 $4,623,000 +$385,937 $1.92 35
2022 Q1 2,052,047 $6,623,000 -$430,212 $3.23 33
2021 Q4 2,169,473 $8,073,000 +$1,421,030 $3.73 32
2021 Q3 1,679,507 $8,621,000 +$3,116,790 $5.15 26
2021 Q2 1,038,443 $5,482,000 +$532,990 $5.28 28
2021 Q1 912,180 $5,265,087 -$7,635,114 $5.81 21
2020 Q4 2,209,512 $14,469,013 +$1,044,013 $6.52 9
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