Latest Period
Q4 2025
Security Snapshot
Opus Genetics, Inc. - Common Stock, $0.0001 par value per share (IRD) Institutional Ownership
CUSIP: 67577R102
13F Institutional Holders and Ownership History from Q4 2020 to Q1 2026
Institutions Reporting
58
Shares (Excl. Options)
27,812,069
Price
$2.01
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- Type / Class
- Equity / Common Stock, $0.0001 par value per share
- Symbol
- IRD on Nasdaq
- Shares outstanding
- 71,813,353
- Price per share
- $4.92
- All holders as of 31 Dec 2025
- Q4 2025
- Total 13F shares
- 27,812,069
- Total reported value
- $55,903,061
- % of total 13F portfolios
- 0%
- Share change
- +8,771,323
- Value change
- +$17,653,005
- Number of holders
- 58
- Price from insider filings
- $4.92
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors
Quick Takeaways
- IRD - Opus Genetics, Inc. - Common Stock, $0.0001 par value per share is tracked under CUSIP 67577R102.
- 58 institutions reported positions in Q4 2025.
- 4 significant owners is listed from Schedule 13D/13G reporting.
What Changed
- Holder count moved from 58 to 9 between Q4 2025 and Q1 2026.
- Reported value moved from $55,903,061 to $2,964,152.
Why This Matters
- You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
- 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.
Source Evidence
Source: SEC Form 13F
Open SEC Evidence
Latest holder context comes from 58 institutions filings for Q4 2025.
Investment Quick Answers
What is CUSIP 67577R102?
CUSIP 67577R102 identifies IRD - Opus Genetics, Inc. - Common Stock, $0.0001 par value per share in SEC 13F datasets.
Where can I see the latest institutional holders?
Review the Q4 2025 holders report and the ownership history table below.
Next ownership checks
Use the next link that matches the question you still need to answer about this security.
- Latest 13F filings when you want to inspect fresh institutional portfolio moves.
- Latest Schedule 13D/13G reports when you need large-owner changes outside the 13F cycle.
- All institutional ownership pages to compare this security with other holder-history pages.
Recent Quarterly Holder Reports
Open recent reporting periods for CUSIP 67577R102:
Significant Owners of Opus Genetics, Inc. - Common Stock, $0.0001 par value per share (IRD) based on Schedule 13D/G filings
| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| PERCEPTIVE ADVISORS LLC | 10% | 0% | $14,420,050 | +$5,353,943 | 7,174,154 | +59% | Perceptive Advisors LLC | 31 Dec 2025 |
| Nantahala Capital Management, LLC | 10% | 0% | $14,318,247 | +$1,755,146 | 7,123,506 | +14% | Nantahala Capital Management, LLC | 31 Dec 2025 |
| Foundation Fighting Blindness Retinal Degeneration Fund | 8% | -49% | $10,819,577 | -$7,880,000 | 5,492,171 | -42% | Foundation Fighting Blindness Retinal Degeneration Fund | 09 Dec 2025 |
| BALYASNY ASSET MANAGEMENT L.P. | 7.4% | $10,271,850 | 5,110,373 | Balyasny Asset Management L.P. | 31 Dec 2025 |
As of 31 Dec 2025, 58 institutional investors reported holding 27,812,069 shares of Opus Genetics, Inc. - Common Stock, $0.0001 par value per share (IRD). This represents 39% of the company’s total 71,813,353 outstanding shares.
Top 25 Institutional Shareholders
The largest institutional shareholders of Opus Genetics, Inc. - Common Stock, $0.0001 par value per share (IRD) together control 38% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| Nantahala Capital Management, LLC | 6.7% | 4,781,330 | +43% | 0.57% | $9,610,473 |
| PERCEPTIVE ADVISORS LLC | 6% | 4,325,000 | 0% | 0.16% | $8,693,250 |
| BIOS Capital Management, LP | 5.1% | 3,683,429 | 0% | 9% | $7,403,692 |
| Balyasny Asset Management L.P. | 3.8% | 2,718,029 | 0.01% | $5,463,238 | |
| VANGUARD GROUP INC | 3.2% | 2,322,897 | +73% | 0% | $4,669,022 |
| MILLENNIUM MANAGEMENT LLC | 2.8% | 2,002,550 | 0% | $4,025,125 | |
| Mink Brook Asset Management LLC | 2.3% | 1,665,631 | +35% | 2.1% | $3,347,918 |
| Opaleye Management Inc. | 1.6% | 1,120,000 | +1.8% | 0.3% | $2,251,200 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 1.5% | 1,104,996 | +16% | 0% | $2,221,042 |
| Bleichroeder LP | 1% | 736,842 | 0% | 0.26% | $1,481,052 |
| GEODE CAPITAL MANAGEMENT, LLC | 0.7% | 504,983 | +7.7% | 0% | $1,015,726 |
| Voss Capital, LP | 0.62% | 441,891 | -21% | 0.05% | $888,201 |
| WELLS FARGO & COMPANY/MN | 0.34% | 241,871 | +6290% | 0% | $486,161 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 0.28% | 201,635 | +898% | 0% | $405,286 |
| CITADEL ADVISORS LLC | 0.25% | 180,721 | +59% | 0% | $363,250 |
| STATE STREET CORP | 0.24% | 173,253 | +19% | 0% | $348,239 |
| MARSHALL WACE, LLP | 0.22% | 157,648 | 0% | $316,873 | |
| TWO SIGMA INVESTMENTS, LP | 0.21% | 151,312 | +40% | 0% | $304,137 |
| BlackRock, Inc. | 0.2% | 141,897 | +208% | 0% | $285,213 |
| Creative Planning | 0.18% | 128,366 | 0% | 0% | $258,016 |
| RENAISSANCE TECHNOLOGIES LLC | 0.18% | 126,309 | -27% | 0% | $253,881 |
| UBS Group AG | 0.13% | 89,818 | +10060% | 0% | $180,534 |
| OMERS ADMINISTRATION Corp | 0.12% | 87,900 | 0% | $176,679 | |
| NORTHERN TRUST CORP | 0.12% | 87,447 | +28% | 0% | $175,768 |
| Texas Capital Bank Wealth Management Services Inc | 0.11% | 78,000 | 0.01% | $156,780 |
Institutional Holders of Opus Genetics, Inc. - Common Stock, $0.0001 par value per share (IRD) across Reporting Periods
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2026 Q1 | 651,375 | $2,964,152 | -$4,850,085 | $4.55 | 9 |
| 2025 Q4 | 27,812,069 | $55,903,061 | +$17,653,005 | $2.01 | 58 |
| 2025 Q3 | 19,026,274 | $31,911,867 | +$2,765,658 | $1.65 | 46 |
| 2025 Q2 | 17,503,196 | $16,482,508 | +$2,741,389 | $0.94 | 43 |
| 2025 Q1 | 14,560,311 | $14,686,745 | +$11,049,669 | $0.98 | 46 |
| 2024 Q4 | 3,678,848 | $4,378,207 | +$106,956 | $1.19 | 42 |
| 2024 Q3 | 2,531,596 | $3,315,513 | -$283,780 | $1.31 | 37 |
| 2024 Q2 | 2,696,097 | $4,126,103 | -$1,250,857 | $1.53 | 37 |
| 2024 Q1 | 3,374,307 | $6,780,798 | -$925,460 | $2.01 | 48 |
| 2023 Q4 | 3,712,141 | $11,173,334 | -$177,249 | $3.01 | 48 |
| 2023 Q3 | 3,768,545 | $12,624,748 | +$43,437 | $3.35 | 50 |
| 2023 Q2 | 3,675,838 | $15,952,413 | +$1,001,477 | $4.34 | 49 |
| 2023 Q1 | 3,457,077 | $12,962,551 | +$1,457,390 | $3.75 | 40 |
| 2022 Q4 | 3,099,588 | $10,946,085 | +$1,241,957 | $3.53 | 34 |
| 2022 Q3 | 2,825,667 | $5,686,000 | +$828,901 | $2.01 | 33 |
| 2022 Q2 | 2,407,242 | $4,623,000 | +$385,937 | $1.92 | 35 |
| 2022 Q1 | 2,052,047 | $6,623,000 | -$430,212 | $3.23 | 33 |
| 2021 Q4 | 2,169,473 | $8,073,000 | +$1,421,030 | $3.73 | 32 |
| 2021 Q3 | 1,679,507 | $8,621,000 | +$3,116,790 | $5.15 | 26 |
| 2021 Q2 | 1,038,443 | $5,482,000 | +$532,990 | $5.28 | 28 |
| 2021 Q1 | 912,180 | $5,265,087 | -$7,635,114 | $5.81 | 21 |
| 2020 Q4 | 2,209,512 | $14,469,013 | +$1,044,013 | $6.52 | 9 |