Nautilus Biotechnology, Inc. - Common stock, par value $0.0001 per share (NAUT) Institutional Ownership

13F Institutional Holders and Ownership History from Q2 2021 to Q4 2025

Type / Class
Equity / Common stock, par value $0.0001 per share
Symbol
NAUT on Nasdaq
Shares outstanding
130,367,883
Price per share
$2.16
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
58,247,098
Total reported value
$113,575,095
% of total 13F portfolios
0%
Share change
+388,600
Value change
+$1,369,427
Number of holders
65
Price from insider filings
$2.16
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of Nautilus Biotechnology, Inc. - Common stock, par value $0.0001 per share (NAUT) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
Mallick Parag 18% +1.2% $48,724,008 +$633,960 22,557,411 +1.3% Parag Mallick 02 Mar 2026
Patel Sujal M 16% +3.8% $45,899,924 +$2,056,823 21,249,965 +4.7% Sujal Patel 02 Mar 2026
PERCEPTIVE ADVISORS LLC 10% +1% $11,149,148 +$192,185 12,815,113 +1.8% Perceptive Advisors LLC 20 Jun 2025

As of 31 Dec 2025, 65 institutional investors reported holding 58,247,098 shares of Nautilus Biotechnology, Inc. - Common stock, par value $0.0001 per share (NAUT). This represents 45% of the company’s total 130,367,883 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of Nautilus Biotechnology, Inc. - Common stock, par value $0.0001 per share (NAUT) together control 44% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
a16z Capital Management, L.L.C. 14% 17,653,917 0% 2.2% $34,425,138
PERCEPTIVE ADVISORS LLC 9.7% 12,594,211 0% 0.45% $24,558,711
Cercano Management LLC 5.5% 7,172,985 0% 0.54% $13,987,321
Madrona Venture Group, LLC 4.6% 6,020,770 0% 53% $11,741,000
VANGUARD GROUP INC 2% 2,598,223 +6.8% 0% $5,066,536
Comprehensive Financial Management LLC 1.7% 2,207,619 0% 0.13% $4,304,857
AMAZON COM INC 1.1% 1,457,055 0% 0.08% $2,841,257
Clarius Group, LLC 0.93% 1,209,646 0% 0.13% $2,358,810
MILLENNIUM MANAGEMENT LLC 0.78% 1,019,996 +5.4% 0% $1,988,992
SENTINEL TRUST CO LBA 0.58% 750,000 0.14% $1,462,000
Tikvah Management LLC 0.56% 726,895 0% 0.39% $1,417,445
ACADIAN ASSET MANAGEMENT LLC 0.47% 611,984 +152% 0% $1,187,000
GEODE CAPITAL MANAGEMENT, LLC 0.43% 560,909 +1.3% 0% $1,094,035
GOLDMAN SACHS GROUP INC 0.23% 297,437 +153% 0% $580,002
DIMENSIONAL FUND ADVISORS LP 0.22% 285,439 -22% 0% $556,319
RENAISSANCE TECHNOLOGIES LLC 0.2% 259,900 -74% 0% $506,805
Alyeska Investment Group, L.P. 0.19% 253,468 0% 0% $494,263
JANE STREET GROUP, LLC 0.16% 206,837 +40% 0% $403,332
STATE STREET CORP 0.15% 201,255 +13% 0% $392,447
HILLMAN CO 0.15% 200,000 0% 0.14% $390,000
BlackRock, Inc. 0.15% 189,431 -6% 0% $369,391
Crewe Advisors LLC 0.1% 136,052 0% 0.02% $265,302
BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.1% 130,000 +4% 0.01% $253,500
GSA CAPITAL PARTNERS LLP 0.1% 124,051 -52% 0.02% $242,000
Qube Research & Technologies Ltd 0.09% 123,121 +138% 0% $240,086

Institutional Holders of Nautilus Biotechnology, Inc. - Common stock, par value $0.0001 per share (NAUT) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 58,247,098 $113,575,095 +$1,369,427 $1.95 65
2025 Q3 57,899,311 $48,912,774 -$1,403,087 $0.84 65
2025 Q2 59,755,012 $43,314,600 -$2,449,905 $0.72 67
2025 Q1 62,775,437 $54,045,644 -$1,026,756 $0.86 86
2024 Q4 63,869,661 $107,299,374 -$821,201 $1.68 86
2024 Q3 64,190,100 $182,943,834 +$1,290,455 $2.85 81
2024 Q2 63,999,578 $149,759,950 +$1,608,547 $2.34 75
2024 Q1 63,240,413 $185,925,873 -$499,885 $2.94 70
2023 Q4 63,424,716 $189,647,655 +$5,847,645 $2.99 74
2023 Q3 45,082,721 $142,463,072 +$769,963 $3.16 74
2023 Q2 44,814,450 $173,427,573 +$1,498,150 $3.87 74
2023 Q1 44,499,314 $123,255,982 -$1,802,223 $2.77 72
2022 Q4 46,081,461 $82,942,228 -$2,657,044 $1.80 78
2022 Q3 56,460,432 $119,696,429 -$2,490,160 $2.12 77
2022 Q2 57,502,356 $154,669,821 +$297,442 $2.69 80
2022 Q1 56,024,124 $243,509,430 -$20,551,922 $4.34 79
2021 Q4 41,913,282 $217,115,889 +$1,259,255 $5.18 77
2021 Q3 40,974,903 $245,092,558 +$9,814,243 $6.14 68
2021 Q2 33,010,619 $331,901,744 +$331,901,478 $10.10 55