Security Snapshot

LeonaBio, Inc. - Common Stock, $0.0001 par value per share (LONA) Institutional Ownership

CUSIP: 04746L203

13F Institutional Holders and Ownership History from Q3 2025 to Q4 2025

Latest Period

Q4 2025

Institutions Reporting

42

Shares (Excl. Options)

6,205,300

Price

$7.57

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Type / Class
Equity / Common Stock, $0.0001 par value per share
Symbol
LONA on Nasdaq
Shares outstanding
3,988,895
Price per share
$6.91
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
6,205,300
Total reported value
$46,703,177
% of total 13F portfolios
0%
Share change
+3,906,117
Value change
+$29,686,872
Number of holders
42
Price from insider filings
$6.91
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

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Quick Takeaways

  • LONA - LeonaBio, Inc. - Common Stock, $0.0001 par value per share is tracked under CUSIP 04746L203.
  • 42 institutions reported positions in Q4 2025.
  • 2 significant owners is listed from Schedule 13D/13G reporting.

What Changed

  • Holder count moved from 32 to 42 between Q3 2025 and Q4 2025.
  • Reported value moved from $7,065,761 to $46,703,177.

Why This Matters

  • You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
  • 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.

Source Evidence

Source: SEC Form 13F

Latest holder context comes from 42 institutions filings for Q4 2025.

Open SEC Evidence

Investment Quick Answers

What is CUSIP 04746L203?
CUSIP 04746L203 identifies LONA - LeonaBio, Inc. - Common Stock, $0.0001 par value per share in SEC 13F datasets.

Where can I see the latest institutional holders?
Review the Q4 2025 holders report and the ownership history table below.

Significant Owners of LeonaBio, Inc. - Common Stock, $0.0001 par value per share (LONA) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
PERCEPTIVE ADVISORS LLC 20% -0.55% $13,052,440 -$68,291 1,859,322 -0.52% Perceptive Advisors LLC 16 Jan 2026
Baselake Partners, LP 1.9% -62% $573,723 -$921,208 75,789 -62% Baselake Partners, LP 31 Dec 2025

As of 31 Dec 2025, 42 institutional investors reported holding 6,205,300 shares of LeonaBio, Inc. - Common Stock, $0.0001 par value per share (LONA). This represents 156% of the company’s total 3,988,895 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of LeonaBio, Inc. - Common Stock, $0.0001 par value per share (LONA) together control 155% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
PERCEPTIVE ADVISORS LLC 47% 1,859,322 +244% 0.26% $14,075,067
ACORN CAPITAL ADVISORS, LLC 13% 501,739 1.3% $3,798,164
NEA Management Company, LLC 12% 464,398 0.18% $3,515,493
TCG Crossover Management, LLC 12% 464,398 0.11% $3,348,507
Commodore Capital LP 12% 464,398 0.23% $3,515,493
ADAR1 Capital Management, LLC 9.9% 393,701 0.22% $2,890,907
Spruce Street Capital LP 9.9% 393,701 0% 0.98% $2,980,317
Kalehua Capital Management LLC 9.9% 393,701 0% 3% $2,980,317
MILLENNIUM MANAGEMENT LLC 8.1% 324,445 0% $2,456,049
VANGUARD GROUP INC 3.9% 153,789 0% 0% $1,164,183
Simplify Asset Management Inc. 3.7% 149,279 0% 0.02% $1,130,042
Propel Bio Management, LLC 3.7% 149,279 0% 0.96% $1,130,042
Seven Fleet Capital Management LP 3.2% 127,951 0% 0.66% $968,589
RENAISSANCE TECHNOLOGIES LLC 1.9% 75,147 +45% 0% $568,863
Pathstone Holdings, LLC 0.97% 38,606 0% 0% $278,903
BlackRock, Inc. 0.94% 37,643 0% 0% $284,958
ACADIAN ASSET MANAGEMENT LLC 0.94% 37,482 -6.7% 0% $282,000
BANK OF AMERICA CORP /DE/ 0.82% 32,840 +0.69% 0% $248,599
GEODE CAPITAL MANAGEMENT, LLC 0.78% 30,944 +1.1% 0% $234,308
Laird Norton Wetherby Trust Company, LLC 0.55% 21,818 +116% 0% $165,162
SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.52% 20,936 -0.24% 0% $158,486
JANE STREET GROUP, LLC 0.33% 13,186 0% $99,818
TWO SIGMA INVESTMENTS, LP 0.27% 10,746 0% $81,347
STATE STREET CORP 0.27% 10,737 0% 0% $81,279
NORTHERN TRUST CORP 0.26% 10,461 0% $79,190

Institutional Holders of LeonaBio, Inc. - Common Stock, $0.0001 par value per share (LONA) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 6,205,300 $46,703,177 +$29,686,872 $7.57 42
2025 Q3 1,706,896 $7,065,761 +$7,065,666 $4.14 32

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