Latest Period
Q1 2026
Security Snapshot
OnKure Therapeutics, Inc. - Class A Common Stock, par value $0.0001 per share (OKUR) Institutional Ownership
CUSIP: 68277Q105
13F Institutional Holders and Ownership History from Q3 2024 to Q1 2026
Institutions Reporting
51
Shares (Excl. Options)
27,520,970
Price
$4.14
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- Security type / class
- Equity / Class A Common Stock, par value $0.0001 per share
- Symbol
- OKUR on Nasdaq
- All holders as of 31 Mar 2026
- Q1 2026
- Total 13F shares
- 27,520,970
- Total 13F value
- $113,936,454
- Portfolio coverage rank
- 0%
- Share change
- +16,663,222
- Value change
- +$69,792,277
- Number of holders
- 51
- Shares outstanding
- 40,281,283
- SEC-reported price per share
- $4.80
- Insider filing price
- $4.80
Latest holder snapshot
5 signals
Issuer context
Names, identifiers, and filing context for this profile.
3 identity fields
13F Shares, Excluding Options vs Price
13F Value, Excluding Options
Total Investors
Key facts
- OKUR - OnKure Therapeutics, Inc. - Class A Common Stock, par value $0.0001 per share is tracked under CUSIP 68277Q105.
- 51 institutions reported positions in Q1 2026.
- 15 significant owners is listed from Schedule 13D/13G reporting.
Change
- Holder count moved from 42 to 51 between Q4 2025 and Q1 2026.
- SEC-reported value moved from $31,975,754 to $113,936,454.
Research use
- You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
- 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.
Evidence
Source: SEC Form 13F
Open SEC evidence
Latest holder context comes from 51 institutions filings for Q1 2026.
Security key
68277Q105
Latest holder period
Q1 2026
13F holders
51
13D/G owners
15
CIK / CUSIP context first
Open Q1 2026 holders
OKUR full holder history
OnKure Therapeutics, Inc. SEC filings
OnKure Therapeutics, Inc. company facts
OnKure Therapeutics, Inc. insider transactions
Broader feeds
Recent Quarterly Holder Reports
Open recent reporting periods for CUSIP 68277Q105:
13D/G owners
Significant owners
Large-stake holder rows connected to Schedule 13D/G evidence.
Rows
15
Security
OKUR
| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| AI Biotechnology LLC | 20% | $24,001,644 | 9,091,532 | AI Biotechnology LLC | 31 Mar 2026 | |||
| RA CAPITAL MANAGEMENT, L.P. | 9.9% | $10,662,208 | 4,038,715 | RA Capital Management, L.P. | 31 Mar 2026 | |||
| ACORN BIOVENTURES, L.P. | 22% | $7,099,185 | 2,839,674 | Anders Hove | 15 May 2025 | |||
| StepStone Group LP | 6.6% | $7,024,016 | 2,660,612 | StepStone Group LP | 31 Mar 2026 | |||
| ADAR1 Capital Management, LLC | 6% | -24% | $10,421,547 | +$6,080,951 | 2,434,941 | +140% | ADAR1 Capital Management, LLC | 31 Mar 2026 |
| Trails Edge Capital Partners, LP | 6% | $6,361,444 | 2,409,638 | Trails Edge Capital Partners, LP | 31 Mar 2026 | |||
| BIOTECHNOLOGY VALUE FUND L P | 5.3% | $10,247,558 | 2,134,908 | BVF PARTNERS L P/IL | 19 May 2026 | |||
| Shay Capital LLC | 6.3% | $2,057,944 | 810,214 | Shay Capital LLC | 15 May 2025 | |||
| Prosight Management, LP | 5.8% | $2,214,578 | 745,649 | Prosight Management, LP | 24 Nov 2025 | |||
| CANTOR FITZGERALD & CO. | 5.2% | $1,606,894 | 669,539 | Cantor Fitzgerald Securities | 30 Jun 2025 | |||
| VANGUARD GROUP INC | 4.9% | -12% | $1,815,303 | -$232,174 | 626,593 | -11% | The Vanguard Group | 31 Dec 2025 |
| HIGHBRIDGE CAPITAL MANAGEMENT LLC | 4.2% | -20% | $1,703,014 | -$380,712 | 542,361 | -18% | Highbridge Capital Management, LLC | 31 Dec 2025 |
| Deep Track Capital, LP | 4.1% | $1,330,932 | 523,989 | Deep Track Capital, LP | 31 Dec 2024 | |||
| CITADEL ADVISORS LLC | 1.7% | $700,612 | 223,125 | Kenneth Griffin | 31 Dec 2025 | |||
| Lundbeckfond Invest A/S | 1.6% | $515,930 | 203,122 | Lundbeckfond Invest A/S | 31 Dec 2024 |
As of 31 Mar 2026, 51 institutional investors reported holding 27,520,970 shares of OnKure Therapeutics, Inc. - Class A Common Stock, par value $0.0001 per share (OKUR). This represents 68% of the company’s total 40,281,283 outstanding shares.
13F concentration
Top 25 institutional shareholders
Largest 13F positions for this security by reported shares and value.
Top holder share
67%
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 9.9% | 3,998,333 | 0.18% | $16,553,099 | |
| ACORN CAPITAL ADVISORS, LLC | 7% | 2,839,674 | 0% | 3.3% | $11,756,250 |
| StepStone Group LP | 6.6% | 2,660,612 | +441% | 5.3% | $11,014,934 |
| ADAR1 Capital Management, LLC | 6% | 2,434,941 | +140% | 0.61% | $10,080,656 |
| Prosight Management, LP | 5.3% | 2,154,381 | +164% | 1.5% | $8,919,137 |
| BVF INC/IL | 4.9% | 1,978,972 | 0.26% | $8,192,944 | |
| Vivo Capital, LLC | 4.8% | 1,927,710 | 0.66% | $7,980,719 | |
| Vestal Point Capital, LP | 4.6% | 1,839,819 | +190% | 0.21% | $7,616,851 |
| Foresite Capital Management VI LLC | 3.6% | 1,445,783 | 1.3% | $5,985,542 | |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 3% | 1,204,819 | 0.01% | $4,987,951 | |
| Sio Capital Management, LLC | 2.7% | 1,078,965 | 0.64% | $4,466,915 | |
| VANGUARD CAPITAL MANAGEMENT LLC | 1.4% | 582,477 | 0% | 0% | $2,411,455 |
| NEA Management Company, LLC | 1.2% | 478,548 | 0% | 0.11% | $1,981,189 |
| Rosalind Advisors, Inc. | 1.1% | 443,763 | -39% | 0.75% | $1,837,179 |
| RENAISSANCE TECHNOLOGIES LLC | 0.94% | 377,250 | +53% | 0% | $1,561,815 |
| Carlyle Group Inc. | 0.67% | 269,895 | 0% | 0.01% | $1,117,365 |
| DV Trading LLC | 0.6% | 240,963 | 0.09% | $997,587 | |
| Affinity Asset Advisors, LLC | 0.6% | 240,963 | 0.06% | $997,587 | |
| Sofinnova Investments, Inc. | 0.35% | 141,700 | 0.03% | $586,638 | |
| Stonepine Capital Management, LLC | 0.33% | 132,578 | 0.48% | $548,873 | |
| Shay Capital LLC | 0.33% | 132,219 | -83% | 0.08% | $547,387 |
| CANTOR FITZGERALD, L. P. | 0.25% | 99,900 | -78% | 0.01% | $413,586 |
| GEODE CAPITAL MANAGEMENT, LLC | 0.25% | 98,750 | +27% | 0% | $408,845 |
| Rangeley Capital, LLC | 0.24% | 95,000 | -34% | 0.43% | $393,300 |
| Aisling Capital Management LP | 0.22% | 88,607 | 0% | 0.08% | $366,833 |
Quarter history
Institutional holders across reporting periods
Holder count, reported shares/value, and median price by quarter.
Periods
7
Latest
Q1 2026
Rows shown
1-7 of 7
| Period | 13F Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2026 Q1 | 27,520,970 | $113,936,454 | +$69,792,277 | $4.14 | 51 |
| 2025 Q4 | 11,055,439 | $31,975,754 | +$1,869,476 | $2.90 | 42 |
| 2025 Q3 | 10,219,418 | $28,103,553 | -$1,295,979 | $2.75 | 41 |
| 2025 Q2 | 10,778,865 | $25,758,405 | -$10,457,913 | $2.39 | 48 |
| 2025 Q1 | 11,945,383 | $50,147,392 | -$1,567,896 | $4.30 | 46 |
| 2024 Q4 | 11,839,453 | $99,220,652 | +$88,963,332 | $8.60 | 50 |
| 2024 Q3 | 3,200 | $5,440 | +$5,440 | $1.70 | 1 |