Latest Period
Q1 2026
Security Snapshot
Zymeworks Inc. - Common Stock, $0.00001 par value per share (ZYME) Institutional Ownership
CUSIP: 98985Y108
13F Institutional Holders and Ownership History from Q3 2022 to Q1 2026
Institutions Reporting
210
Shares (Excl. Options)
70,281,337
Price
$25.04
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- Security type / class
- Equity / Common Stock, $0.00001 par value per share
- Symbol
- ZYME on Nasdaq
- All holders as of 31 Mar 2026
- Q1 2026
- Total 13F shares
- 70,281,337
- Total 13F value
- $1,760,015,725
- Portfolio coverage rank
- 0%
- Share change
- -1,173,936
- Value change
- -$36,278,786
- Number of holders
- 210
- Shares outstanding
- 73,761,855
- SEC-reported price per share
- $24.57
- Insider filing price
- $24.57
Latest holder snapshot
5 signals
Issuer context
Names, identifiers, and filing context for this profile.
3 identity fields
13F Shares, Excluding Options vs Price
13F Value, Excluding Options
Total Investors
Key facts
- ZYME - Zymeworks Inc. - Common Stock, $0.00001 par value per share is tracked under CUSIP 98985Y108.
- 210 institutions reported positions in Q1 2026.
- 7 significant owners is listed from Schedule 13D/13G reporting.
Change
- Holder count moved from 208 to 210 between Q4 2025 and Q1 2026.
- SEC-reported value moved from $1,881,298,833 to $1,760,015,725.
Research use
- You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
- 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.
Evidence
Source: SEC Form 13F
Open SEC evidence
Latest holder context comes from 210 institutions filings for Q1 2026.
Security key
98985Y108
Latest holder period
Q1 2026
13F holders
210
13D/G owners
7
CIK / CUSIP context first
Open Q1 2026 holders
ZYME full holder history
Zymeworks Inc. SEC filings
Zymeworks Inc. company facts
Zymeworks Inc. insider transactions
Broader feeds
Recent Quarterly Holder Reports
Open recent reporting periods for CUSIP 98985Y108:
13D/G owners
Significant owners
Large-stake holder rows connected to Schedule 13D/G evidence.
Rows
7
Security
ZYME
| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| EcoR1 Capital, LLC | 31% | 0% | $420,817,508 | 22,970,388 | 0% | EcoR1 Capital, LLC | 16 Nov 2025 | |
| Rubric Capital Management LP | 9.5% | +23% | $175,280,000 | +$31,300,000 | 7,000,000 | +22% | Rubric Capital Management LP | 31 Mar 2026 |
| PERCEPTIVE ADVISORS LLC | 5.4% | $99,527,035 | 3,974,579 | Perceptive Advisors LLC | 08 Apr 2026 | |||
| BIOTECHNOLOGY VALUE FUND L P | 5.2% | $67,271,988 | 3,938,641 | BVF PARTNERS L P/IL | 30 Sep 2025 | |||
| Redmile Group, LLC | 4.9% | -12% | $63,294,210 | -$7,598,499 | 3,705,750 | -11% | Redmile Group, LLC | 30 Sep 2025 |
| BlackRock, Inc. | 4.8% | $44,677,977 | 3,559,828 | BlackRock, Inc. | 30 Jun 2025 | |||
| MORGAN STANLEY | 3.4% | -40% | $67,062,249 | -$40,886,430 | 2,519,243 | -38% | Morgan Stanley | 31 Dec 2025 |
As of 31 Mar 2026, 210 institutional investors reported holding 70,281,337 shares of Zymeworks Inc. - Common Stock, $0.00001 par value per share (ZYME). This represents 95% of the company’s total 73,761,855 outstanding shares.
13F concentration
Top 25 institutional shareholders
Largest 13F positions for this security by reported shares and value.
Top holder share
83%
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| EcoR1 Capital, LLC | 31% | 22,970,388 | 0% | 25% | $575,178,516 |
| Rubric Capital Management LP | 9.5% | 7,000,000 | +22% | 2.1% | $175,280,000 |
| BlackRock, Inc. | 6.2% | 4,553,888 | -0.91% | 0% | $114,029,354 |
| BVF INC/IL | 5.1% | 3,734,142 | -5.2% | 3% | $93,502,916 |
| PERCEPTIVE ADVISORS LLC | 4.8% | 3,510,078 | +7.6% | 1.7% | $87,892,353 |
| MORGAN STANLEY | 3.4% | 2,480,568 | -4.3% | 0% | $62,113,426 |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 2.6% | 1,908,039 | +4.7% | 0.06% | $47,777,297 |
| VANGUARD CAPITAL MANAGEMENT LLC | 2.3% | 1,705,580 | 0% | 0% | $42,707,723 |
| CITADEL ADVISORS LLC | 1.6% | 1,150,018 | +350% | 0.02% | $28,796,451 |
| DIMENSIONAL FUND ADVISORS LP | 1.5% | 1,139,135 | -1.7% | 0.01% | $28,518,914 |
| Nextech Invest, Ltd. | 1.5% | 1,113,946 | 0% | 2% | $27,893,208 |
| STATE STREET CORP | 1.4% | 1,011,777 | -2.5% | 0% | $25,334,896 |
| Capricorn Fund Managers Ltd | 1.4% | 1,007,210 | -1.5% | 3.9% | $25,220,538 |
| DEUTSCHE BANK AG\ | 1.2% | 921,250 | -42% | 0.01% | $23,068,100 |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 1% | 743,898 | +6.3% | 0.01% | $18,627,206 |
| Assenagon Asset Management S.A. | 0.99% | 727,986 | +12% | 0.03% | $18,228,769 |
| FMR LLC | 0.9% | 667,153 | +19% | 0% | $16,705,506 |
| GEODE CAPITAL MANAGEMENT, LLC | 0.89% | 659,940 | +1.8% | 0% | $16,524,344 |
| Nuveen, LLC | 0.88% | 651,662 | +0.51% | 0% | $16,317,616 |
| GOLDMAN SACHS GROUP INC | 0.81% | 599,486 | +43% | 0% | $15,011,130 |
| MPM BIOIMPACT LLC | 0.77% | 565,249 | 1.1% | $14,153,835 | |
| Prosight Management, LP | 0.73% | 539,049 | +1.6% | 2.2% | $13,497,787 |
| Qube Research & Technologies Ltd | 0.69% | 511,937 | +7.9% | 0.02% | $12,818,902 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 0.68% | 499,875 | 0% | 0% | $12,516,870 |
| Redmile Group, LLC | 0.67% | 491,654 | 0% | 0.82% | $12,311,016 |
Quarter history
Institutional holders across reporting periods
Holder count, reported shares/value, and median price by quarter.
Periods
15
Latest
Q1 2026
Rows shown
1-15 of 15
| Period | 13F Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2026 Q1 | 70,281,337 | $1,760,015,725 | -$36,278,786 | $25.04 | 210 |
| 2025 Q4 | 71,450,392 | $1,881,298,833 | -$32,229,794 | $26.33 | 208 |
| 2025 Q3 | 73,689,534 | $1,258,648,393 | -$22,925,180 | $17.08 | 181 |
| 2025 Q2 | 75,621,323 | $949,023,010 | +$68,009,464 | $12.55 | 179 |
| 2025 Q1 | 70,389,436 | $838,494,320 | +$42,500,933 | $11.91 | 182 |
| 2024 Q4 | 66,481,090 | $973,230,925 | -$246,877 | $14.64 | 171 |
| 2024 Q3 | 66,502,275 | $834,701,900 | -$15,271,356 | $12.55 | 161 |
| 2024 Q2 | 68,183,439 | $580,274,097 | +$16,468,836 | $8.51 | 160 |
| 2024 Q1 | 67,744,225 | $712,627,244 | +$31,495,473 | $10.52 | 167 |
| 2023 Q4 | 64,825,365 | $673,552,112 | +$31,038,276 | $10.39 | 153 |
| 2023 Q3 | 62,318,186 | $395,187,634 | -$7,310,307 | $6.34 | 136 |
| 2023 Q2 | 63,418,288 | $547,948,381 | +$55,194,956 | $8.64 | 135 |
| 2023 Q1 | 56,707,830 | $512,639,046 | +$19,986,782 | $9.04 | 113 |
| 2022 Q4 | 55,146,033 | $433,446,373 | +$429,612,295 | $7.86 | 89 |
| 2022 Q3 | 78,394 | $482,000 | +$482,000 | $6.15 | 1 |