PERCEPTIVE ADVISORS LLC

Holdings History for Amylyx Pharmaceuticals, Inc. - Common Stock, $0.0001 par value per share (AMLX)

Symbol: AMLX on Nasdaq
Investment type: Equity / Common Stock, $0.0001 par value per share
Latest Disclosed Shares Owned: 8,952,365 shares
Security Ownership %: 8.2%

Shares, Excluding Options vs Price

Value, Excluding Options

Perceptive Advisors LLC ownership in Amylyx Pharmaceuticals, Inc. Common Stock, $0.0001 par value per share (AMLX)

14 Nov 2025 - Perceptive Advisors LLC has filed an SCHEDULE 13G/A form with the Securities and Exchange Commission (SEC) disclosing ownership of 8,952,365 shares of Amylyx Pharmaceuticals, Inc. Common Stock, $0.0001 par value per share (AMLX). This represents 8.2% ownership of the company. In their previous filing dated 15 May 2025, PERCEPTIVE ADVISORS LLC had reported owning 7,874,348 shares, indicating an increase of +14%. .

Reporting Name	Ownership %	Change	Value $	Shares owned	Change	Activity %	Price	Form	Report date	Filing time
Perceptive Advisors LLC	8.2%	-6.7%	$121,662,640	8,952,365	+1,078,017	+14%	$13.59	13G/A	30 Sep 2025	14 Nov 2025, 16:00
Perceptive Advisors LLC	8.8%	+11%	$42,206,505	7,874,348	+1,100,000	+16%	$5.36	13G/A	31 Mar 2025	15 May 2025, 16:30
Perceptive Advisors LLC	7.9%		$36,310,505	6,774,348			$5.36	13G/A	31 Dec 2024	14 Feb 2025, 16:15

Holdings date	Option	Weight	Change	Value $	Shares	Change	Activity %	Price	All Holders
31 Dec 2025		1.8%	-0.15%	$100,081,375	8,284,882	-667,483	-7.5%	$12.08	Q4 2025
30 Sep 2025		3.6%	+0.42%	$121,662,640	8,952,365	+1,050,000	+13%	$13.59	Q3 2025
30 Jun 2025		1.9%	+0.01%	$50,654,160	7,902,365	+28,017	+0.36%	$6.41	Q2 2025
31 Mar 2025		0.99%	+0.14%	$27,875,192	7,874,348	+1,100,000	+16%	$3.54	Q1 2025
31 Dec 2024		0.71%	+0.49%	$25,607,035	6,774,348	+4,648,699	+219%	$3.78	Q4 2024
30 Sep 2024		0.15%	+0.15%	$6,887,103	2,125,649	+2,125,649	NEW	$3.24	Q3 2024
30 Jun 2024			-0.02%	$0	0	-300,000	-100%	$14.29	Q2 2024
30 Jun 2024	call		-12%	$0	0	-1,679,125	-100%	$14.29	Q2 2024
31 Mar 2024		0.02%	-0.1%	$852,000	300,000	-1,569,125	-84%	$2.84	Q1 2024
31 Mar 2024	call	12%	+79%	$4,768,715	1,679,125	+1,679,125	NEW	$2.84	Q1 2024
31 Dec 2023		0.62%	-0.27%	$27,513,520	1,869,125	-819,748	-30%	$14.72	Q4 2023
30 Sep 2023		1.7%	-1.3%	$49,233,265	2,688,873	-2,185,046	-45%	$18.31	Q3 2023
30 Jun 2023		3.1%	-0.73%	$105,130,433	4,873,919	-1,160,725	-19%	$21.57	Q2 2023
31 Mar 2023		5.2%	-0.05%	$177,056,455	6,034,644	-53,689	-0.88%	$29.34	Q1 2023
31 Dec 2022		6.5%	+0.66%	$224,963,904	6,088,333	+616,300	+11%	$36.95	Q4 2022
30 Sep 2022		4.5%	+1.6%	$154,038,000	5,472,033	+1,931,625	+55%	$28.15	Q3 2022
30 Jun 2022		2.5%	+1.5%	$68,188,000	3,540,408	+2,066,301	+140%	$19.26	Q2 2022
31 Mar 2022		0.45%	+0.45%	$18,942,000	1,474,107	+1,474,107	NEW	$12.85	Q1 2022

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.