Insider Trading & Ownership of PERCEPTIVE ADVISORS LLC

Location
New York, NY
Summary
The estimated value of insider holdings of PERCEPTIVE ADVISORS LLC is at least $1,024,329,777 dollars as of 18 Mar 2026. PERCEPTIVE ADVISORS LLC is the 10%+ Owner of Crinetics Pharmaceuticals, Inc. and owns shares of Crinetics Pharmaceuticals, Inc. (CRNX) stock worth about $200.34M. PERCEPTIVE ADVISORS LLC is the 10%+ Owner of VBI Vaccines Inc/BC and owns shares of VBI Vaccines Inc/BC stock worth about $137.17M. PERCEPTIVE ADVISORS LLC is the 10%+ Owner of SOLENO THERAPEUTICS INC and owns shares of SOLENO THERAPEUTICS INC (SLNO) stock worth about $112.18M. PERCEPTIVE ADVISORS LLC is the Director of Immatics N.V. and owns shares of Immatics N.V. (IMTX) stock worth about $102.8M. PERCEPTIVE ADVISORS LLC is the Director, 10%+ Owner of MeiraGTx Holdings plc and owns shares of MeiraGTx Holdings plc (MGTX) stock worth about $93.42M. PERCEPTIVE ADVISORS LLC is the 10%+ Owner of ALBIREO PHARMA, INC. and owns shares of ALBIREO PHARMA, INC. stock worth about $84.96M. PERCEPTIVE ADVISORS LLC is the Director of Astria Therapeutics, Inc. and owns shares of Astria Therapeutics, Inc. stock worth about $67.17M. PERCEPTIVE ADVISORS LLC is the 10%+ Owner of ADMA BIOLOGICS, INC. and owns shares of ADMA BIOLOGICS, INC. (ADMA) stock worth about $59.95M. PERCEPTIVE ADVISORS LLC is the 10%+ Owner of Verrica Pharmaceuticals Inc. and owns shares of Verrica Pharmaceuticals Inc. (VRCA) stock worth about $51.4M. PERCEPTIVE ADVISORS LLC is the 10%+ Owner of Aldeyra Therapeutics, Inc. and owns shares of Aldeyra Therapeutics, Inc. (ALDX) stock worth about $27.83M. PERCEPTIVE ADVISORS LLC is the 10%+ Owner of Orchestra BioMed Holdings, Inc. and owns shares of Orchestra BioMed Holdings, Inc. (OBIO) stock worth about $18.68M. PERCEPTIVE ADVISORS LLC is the 10%+ Owner of AGILE THERAPEUTICS INC and owns shares of AGILE THERAPEUTICS INC stock worth about $18.41M. PERCEPTIVE ADVISORS LLC is the Director, 10%+ Owner of Athira Pharma, Inc. and owns shares of LeonaBio, Inc. (LONA) stock worth about $17.72M. PERCEPTIVE ADVISORS LLC is the 10%+ Owner of VYNE Therapeutics Inc. and owns shares of VYNE Therapeutics Inc. (VYNE) stock worth about $11.25M. PERCEPTIVE ADVISORS LLC is the Former 10% Owner of CARGO Therapeutics, Inc. and owns shares of CARGO Therapeutics, Inc. stock worth about $5M. PERCEPTIVE ADVISORS LLC is the 10%+ Owner of Acrivon Therapeutics, Inc. and owns shares of Acrivon Therapeutics, Inc. (ACRV) stock worth about $4.16M. PERCEPTIVE ADVISORS LLC is the Director, 10%+ Owner of Adagio Medical Holdings, Inc. and owns shares of Adagio Medical Holdings, Inc. (ADGM) stock worth about $3.51M. PERCEPTIVE ADVISORS LLC is the 10%+ Owner of Rain Therapeutics Inc. and owns shares of Rain Oncology Inc. stock worth about $3.01M. PERCEPTIVE ADVISORS LLC is the 10%+ Owner of IsoPlexis Corp and owns shares of IsoPlexis Corp stock worth about $2.97M. PERCEPTIVE ADVISORS LLC is the 10%+ Owner of CHEMBIO DIAGNOSTICS, INC. and owns shares of CHEMBIO DIAGNOSTICS, INC. stock worth about $1.65M. PERCEPTIVE ADVISORS LLC is the 10%+ Owner of Quotient Ltd and owns shares of Quotient Ltd stock worth about $635.6K. PERCEPTIVE ADVISORS LLC is the Director, 10%+ Owner of LianBio and owns shares of LianBio (LIANY) stock worth about $81.3K. PERCEPTIVE ADVISORS LLC is the 10%+ Owner of Lyra Therapeutics, Inc. and owns shares of Lyra Therapeutics, Inc. (LYRA) stock worth about $54.7K.
Signature
/s/ Joseph Edelman - for Perceptive Advisors LLC, By: Joseph Edelman, its managing member
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Quick Takeaways

  • PERCEPTIVE ADVISORS LLC has 29 issuer positions tracked on this page.
  • Estimated disclosed ownership value: $1,024,329,777.
  • Recent insider filing activity is available below.

What Changed

  • Largest disclosed position: Crinetics Pharmaceuticals, Inc. ($200,336,855).
  • Past-year value change for that position: .

Why This Matters

  • This page translates Forms 3/4/5 into a quick ownership context before you inspect each transaction row.
  • You can cross-check role, issuer, and filing chronology directly against the SEC source.

Source Evidence

Filed on Form 4

Insider ownership context is sourced from SEC Forms 3, 4, and 5.

See Original Filing

Ownership of PERCEPTIVE ADVISORS LLC

Symbol Company Relationship Holdings Value Past Year Net Change Change % Report Period
CRNX Crinetics Pharmaceuticals, Inc. 10%+ Owner $200,336,855 18 Apr 2022
VBIV VBI Vaccines Inc/BC 10%+ Owner $137,168,813 04 Apr 2023
SLNO SOLENO THERAPEUTICS INC 10%+ Owner $112,175,587 26 Sep 2023
IMTX Immatics N.V. Director $102,796,214 18 Mar 2026
MGTX MeiraGTx Holdings plc Director, 10%+ Owner $93,416,772 31 Dec 2025
ALBO ALBIREO PHARMA, INC. 10%+ Owner $84,959,867 11 Oct 2022
ATXS Astria Therapeutics, Inc. Director $67,172,360 01 Feb 2024
ADMA ADMA BIOLOGICS, INC. 10%+ Owner $59,945,935 28 Sep 2021
VRCA Verrica Pharmaceuticals Inc. 10%+ Owner $51,398,078 27 Dec 2023
ALDX Aldeyra Therapeutics, Inc. 10%+ Owner $27,829,793 03 Apr 2025
OBIO Orchestra BioMed Holdings, Inc. 10%+ Owner $18,679,378 +$6,049,850 +48% 01 Aug 2025
AGRX AGILE THERAPEUTICS INC 10%+ Owner $18,406,312 13 Oct 2021
LONA Athira Pharma, Inc. Director, 10%+ Owner $17,718,931 23 Dec 2025
VYNE VYNE Therapeutics Inc. 10%+ Owner $11,251,930 16 Aug 2021
CRGX CARGO Therapeutics, Inc. Former 10% Owner $4,999,995 14 Nov 2023
ACRV Acrivon Therapeutics, Inc. 10%+ Owner $4,159,546 30 Apr 2025
ADGM Adagio Medical Holdings, Inc. Director, 10%+ Owner $3,505,231 +$3,505,232 +100% 20 Oct 2025
RAIN Rain Therapeutics Inc. 10%+ Owner $3,009,293 07 Oct 2021
ISO IsoPlexis Corp 10%+ Owner $2,974,560 12 Oct 2021
CEMI CHEMBIO DIAGNOSTICS, INC. 10%+ Owner $1,652,698 04 Apr 2023
QTNT Quotient Ltd 10%+ Owner $635,617 31 Oct 2022
LIANY LianBio Director, 10%+ Owner $81,310 15 Feb 2024
LYRA Lyra Therapeutics, Inc. 10%+ Owner $54,702 -$526,734 -91% 11 Nov 2025
CERE Cerevel Therapeutics Holdings, Inc. Director $0 20 Feb 2024
LABP Landos Biopharma, Inc. 10%+ Owner 10 Jan 2023
CYPH LEAP THERAPEUTICS, INC. 10%+ Owner 24 Sep 2021
NAUT Nautilus Biotechnology, Inc. Director, 10%+ Owner 14 Jun 2024
SLDB Solid Biosciences Inc. Director, 10%+ Owner 09 Mar 2026
VAPO VAPOTHERM INC 10%+ Owner 17 Jun 2024

Insider Transactions Reported by PERCEPTIVE ADVISORS LLC:

Sym Company Class Transaction % Value $ * Price $ Shares Shares After Date Ownership
* An asterisk sign (*) next to the price indicates that the price is likely invalid.
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