Latest Period
Q2 2026
Security Snapshot
RHYTHM PHARMACEUTICALS, INC. - Common Stock, $0.001 par value per share (RYTM) Institutional Ownership
CUSIP: 76243J105
13F Institutional Holders and Ownership History from Q4 2017 to Q2 2026
Institutions Reporting
303
Shares (Excl. Options)
77,226,625
Price
$111.03
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- Security type / class
- Equity / Common Stock, $0.001 par value per share
- Symbol
- RYTM on Nasdaq
- All holders as of 30 Jun 2026
- Q2 2026
- Total 13F shares
- 77,226,625
- Total 13F value
- $8,550,132,466
- Portfolio coverage rank
- 0.01%
- Share change
- +3,702,107
- Value change
- +$437,348,617
- Number of holders
- 303
- Shares outstanding
- 69,012,275
- SEC-reported price per share
- $105.74
- Insider filing price
- $105.74
Latest holder snapshot
5 signals
Issuer context
Names, identifiers, and filing context for this profile.
3 identity fields
13F Shares, Excluding Options vs Price
13F Value, Excluding Options
Total Investors
Key facts
- RYTM - RHYTHM PHARMACEUTICALS, INC. - Common Stock, $0.001 par value per share is tracked under CUSIP 76243J105.
- 303 institutions reported positions in Q2 2026.
- 7 significant owners is listed from Schedule 13D/13G reporting.
Change
- Holder count moved from 284 to 303 between Q1 2026 and Q2 2026.
- SEC-reported value moved from $6,388,316,182 to $8,550,132,466.
Research use
- You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
- 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.
Evidence
Source: SEC Form 13F
Open SEC evidence
Latest holder context comes from 303 institutions filings for Q2 2026.
Security key
76243J105
Latest holder period
Q2 2026
13F holders
303
13D/G owners
7
CIK / CUSIP context first
Open Q2 2026 holders
RYTM full holder history
RHYTHM PHARMACEUTICALS, INC. SEC filings
RHYTHM PHARMACEUTICALS, INC. company facts
RHYTHM PHARMACEUTICALS, INC. insider transactions
Broader feeds
Recent Quarterly Holder Reports
Open recent reporting periods for CUSIP 76243J105:
13D/G owners
Significant owners
Large-stake holder rows connected to Schedule 13D/G evidence.
Rows
7
Security
RYTM
| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 9.9% | +13% | $662,816,935 | +$109,906,623 | 6,666,837 | +20% | RA Capital Management, L.P. | 31 Dec 2025 |
| BAKER BROS. ADVISORS LP | 8.9% | $360,984,750 | 5,604,483 | Baker Bros. Advisors LP | 31 Mar 2025 | |||
| BlackRock, Inc. | 6.9% | $281,130,327 | 4,364,700 | BlackRock, Inc. | 31 Mar 2025 | |||
| PERCEPTIVE ADVISORS LLC | 5.1% | -24% | $303,708,528 | -$77,990,196 | 3,519,626 | -20% | Perceptive Advisors LLC | 31 Mar 2026 |
| PRIMECAP MANAGEMENT CO/CA/ | 5.2% | -20% | $345,849,272 | -$77,964,170 | 3,478,669 | -18% | PRIMECAP MANAGEMENT CO/CA/ | 31 Dec 2025 |
| VANGUARD CAPITAL MANAGEMENT LLC | 5% | $298,563,575 | 3,432,949 | Vanguard Capital Management | 31 Mar 2026 | |||
| GOLDMAN SACHS GROUP INC | 3% | $117,157,406 | 1,818,932 | THE GOLDMAN SACHS GROUP, INC. | 31 Dec 2024 |
As of 30 Jun 2026, 303 institutional investors reported holding 77,226,625 shares of RHYTHM PHARMACEUTICALS, INC. - Common Stock, $0.001 par value per share (RYTM). This represents 112% of the company’s total 69,012,275 outstanding shares.
13F concentration
Top 25 institutional shareholders
Largest 13F positions for this security by reported shares and value.
Top holder share
84%
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 9.7% | 6,666,837 | 0% | 6.4% | $740,218,912 |
| BlackRock, Inc. | 8.9% | 6,156,902 | -1.3% | 0.01% | $683,600,828 |
| BAKER BROS. ADVISORS LP | 8.1% | 5,604,483 | 0% | 3.1% | $622,265,747 |
| PRIMECAP MANAGEMENT CO/CA/ | 4.6% | 3,168,853 | -7.3% | 0.21% | $351,837,748 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 4.5% | 3,136,895 | +3.2% | 0.02% | $348,289,452 |
| VANGUARD CAPITAL MANAGEMENT LLC | 4.4% | 3,005,977 | +1.3% | 0.01% | $333,753,626 |
| JPMORGAN CHASE & CO | 3.8% | 2,652,746 | +71% | 0.02% | $292,178,898 |
| PERCEPTIVE ADVISORS LLC | 3.7% | 2,586,295 | +9% | 4.5% | $287,156,334 |
| STATE STREET CORP | 3.7% | 2,573,529 | +13% | 0.01% | $285,728,722 |
| PRICE T ROWE ASSOCIATES INC /MD/ | 3.7% | 2,566,171 | +55% | 0.03% | $284,923,000 |
| WESTFIELD CAPITAL MANAGEMENT CO LP | 3.2% | 2,208,595 | +14% | 0.8% | $245,220,303 |
| GOLDMAN SACHS GROUP INC | 3.1% | 2,126,502 | +8.2% | 0.02% | $236,105,516 |
| FEDERATED HERMES, INC. | 2.6% | 1,785,716 | +39% | 0.29% | $198,268,047 |
| Polar Capital Holdings Plc | 2.4% | 1,663,632 | +3% | 0.52% | $184,713,061 |
| GEODE CAPITAL MANAGEMENT, LLC | 2.2% | 1,533,698 | +8.3% | 0.01% | $170,320,392 |
| Capital Research Global Investors | 2.2% | 1,532,303 | +37% | 0.02% | $170,131,602 |
| CITADEL ADVISORS LLC | 1.8% | 1,263,652 | -11% | 0.08% | $140,303,282 |
| Checkpoint Capital L.P. | 1.7% | 1,186,000 | -3.4% | 34% | $131,681,580 |
| Siren, L.L.C. | 1.6% | 1,136,275 | +57% | 2.6% | $126,160,613 |
| MORGAN STANLEY | 1.6% | 1,112,240 | +58% | 0.01% | $123,492,178 |
| FMR LLC | 1.5% | 1,025,840 | -39% | 0% | $113,899,059 |
| Pictet Asset Management Holding SA | 1.4% | 957,785 | +44% | 0.1% | $106,252,095 |
| Jupiter Topco LLC | 1.3% | 925,490 | 0% | 0.04% | $102,751,821 |
| ALLIANCEBERNSTEIN L.P. | 1.3% | 894,723 | -1.7% | 0.03% | $77,814,059 |
| Woodline Partners LP | 1.1% | 758,891 | 0% | 0.26% | $84,259,668 |
Quarter history
Institutional holders across reporting periods
Holder count, reported shares/value, and median price by quarter.
Periods
35
Latest
Q2 2026
Rows shown
1-25 of 35
| Period | 13F Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2026 Q2 | 77,226,625 | $8,550,132,466 | +$437,348,617 | $111.03 | 303 |
| 2026 Q1 | 73,450,451 | $6,388,316,182 | -$50,528,332 | $86.97 | 284 |
| 2025 Q4 | 72,869,773 | $7,800,510,442 | +$220,704,819 | $107.04 | 279 |
| 2025 Q3 | 70,886,984 | $7,158,776,142 | +$449,472,938 | $100.99 | 263 |
| 2025 Q2 | 66,543,505 | $4,204,958,379 | +$136,584,141 | $63.19 | 225 |
| 2025 Q1 | 64,595,384 | $3,424,910,613 | -$18,829,096 | $52.97 | 226 |
| 2024 Q4 | 64,917,500 | $3,634,217,578 | -$158,677,402 | $55.98 | 202 |
| 2024 Q3 | 67,700,036 | $3,546,202,706 | -$85,917,668 | $52.39 | 175 |
| 2024 Q2 | 69,300,680 | $2,846,175,742 | +$52,795,226 | $41.06 | 164 |
| 2024 Q1 | 68,030,458 | $2,946,208,413 | +$55,358,404 | $43.33 | 166 |
| 2023 Q4 | 66,696,112 | $3,065,811,725 | -$41,849,707 | $45.97 | 167 |
| 2023 Q3 | 68,143,293 | $1,562,080,292 | +$58,456,223 | $22.92 | 143 |
| 2023 Q2 | 66,212,640 | $1,092,127,229 | +$94,106,398 | $16.49 | 116 |
| 2023 Q1 | 60,335,883 | $1,076,382,910 | -$49,077,961 | $17.84 | 125 |
| 2022 Q4 | 62,378,764 | $1,816,485,551 | +$85,568,575 | $29.12 | 116 |
| 2022 Q3 | 59,549,165 | $1,446,896,472 | +$426,232,319 | $24.50 | 99 |
| 2022 Q2 | 45,934,145 | $190,627,988 | -$18,795,957 | $4.15 | 82 |
| 2022 Q1 | 48,841,709 | $562,605,977 | +$4,688,818 | $11.52 | 105 |
| 2021 Q4 | 48,449,400 | $483,522,595 | -$537,879 | $9.98 | 94 |
| 2021 Q3 | 47,950,622 | $626,233,206 | +$2,428,146 | $13.06 | 93 |
| 2021 Q2 | 42,614,232 | $834,516,313 | -$3,429,160 | $19.58 | 101 |
| 2021 Q1 | 47,577,014 | $1,011,965,096 | +$147,271,703 | $21.27 | 119 |
| 2020 Q4 | 40,510,233 | $1,201,291,923 | +$39,479,834 | $29.73 | 114 |
| 2020 Q3 | 39,249,591 | $850,611,960 | -$43,710,727 | $21.67 | 114 |
| 2020 Q2 | 41,237,373 | $919,577,883 | +$11,957,883 | $22.30 | 89 |