Security Snapshot

Alto Neuroscience, Inc. - Common Stock, par value $0.0001 per share (ANRO) Institutional Ownership

CUSIP: 02157Q109

13F Institutional Holders and Ownership History from Q1 2024 to Q1 2026

Latest Period

Q1 2026

Institutions Reporting

110

Shares (Excl. Options)

26,830,701

Price

$22.48

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Type / Class
Equity / Common Stock, par value $0.0001 per share
Symbol
ANRO on NYSE
Shares outstanding
31,755,000
Price per share
$27.33
All holders as of 31 Mar 2026
Q1 2026
Total 13F shares
26,830,701
Total reported value
$602,479,913
% of total 13F portfolios
0%
Share change
+2,359,630
Value change
+$54,953,807
Number of holders
110
Price from insider filings
$27.33
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Key facts

  • ANRO - Alto Neuroscience, Inc. - Common Stock, par value $0.0001 per share is tracked under CUSIP 02157Q109.
  • 110 institutions reported positions in Q1 2026.
  • 9 significant owners is listed from Schedule 13D/13G reporting.

Change

  • Holder count moved from 96 to 110 between Q4 2025 and Q1 2026.
  • Reported value moved from $435,860,904 to $602,479,913.

Research use

  • You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
  • 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.

Evidence

Source: SEC Form 13F

Latest holder context comes from 110 institutions filings for Q1 2026.

Open SEC Evidence

Security key

02157Q109

Latest holder period

Q1 2026

13F holders

110

13D/G owners

9

CIK / CUSIP context first

Significant Owners of Alto Neuroscience, Inc. - Common Stock, par value $0.0001 per share (ANRO) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
Commodore Capital LP 9.9% 0% $77,791,742 +$7,426,527 3,588,180 +11% Commodore Capital LP 31 Mar 2026
PERCEPTIVE ADVISORS LLC 10% +38% $53,623,911 +$20,798,926 3,249,934 +63% Perceptive Advisors LLC 31 Dec 2025
Sirenia Capital Management LP 7.9% $56,185,606 2,591,587 Sirenia Capital Management LP 31 Mar 2026
Vestal Point Capital, LP 6.5% -19% $44,749,146 -$9,125,654 2,064,075 -17% Vestal Point Capital, LP 31 Mar 2026
ARMISTICE CAPITAL, LLC 4.9% -16% $23,546,880 -$981,120 1,536,000 -4% Armistice Capital, LLC 31 Dec 2025
FMR LLC 4.7% $2,885,445 1,265,546 FMR LLC 31 Dec 2024
Point72 Asset Management, L.P. 3.7% -58% $25,384,353 -$35,845,929 1,170,865 -59% Steven A. Cohen 31 Mar 2026
K2 HealthVentures Equity Trust LLC 2.4% -53% $13,018,418 -$13,676,190 788,995 -51% K2 HealthVentures Equity Trust LLC 31 Dec 2025
BlackRock, Inc. 2.1% $1,234,213 561,363 BlackRock, Inc. 30 Jun 2025

As of 31 Mar 2026, 110 institutional investors reported holding 26,830,701 shares of Alto Neuroscience, Inc. - Common Stock, par value $0.0001 per share (ANRO). This represents 84% of the company’s total 31,755,000 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of Alto Neuroscience, Inc. - Common Stock, par value $0.0001 per share (ANRO) together control 74% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
Alpha Wave Global, LP 12% 3,707,757 0% 11% $83,350,377
Commodore Capital LP 8.6% 2,723,196 +49% 3.5% $61,217,446
Vestal Point Capital, LP 6.5% 2,064,075 -17% 1.3% $46,400,406
PERCEPTIVE ADVISORS LLC 6.3% 2,009,893 +13% 0.89% $45,182,395
Spruce Street Capital LP 4.2% 1,325,210 +495% 7% $29,116,321
VANGUARD CAPITAL MANAGEMENT LLC 3.8% 1,207,025 0% 0% $27,133,922
FRANKLIN RESOURCES INC 3.5% 1,101,874 -1.6% 0.01% $24,770,128
Vivo Capital, LLC 3.3% 1,035,551 0% 1.9% $23,279,186
ARMISTICE CAPITAL, LLC 2.9% 912,000 -41% 0.68% $20,501,760
MILLENNIUM MANAGEMENT LLC 2.6% 821,982 +30% 0.01% $18,478,155
72 Investment Holdings, LLC 2.1% 667,778 0% 30% $15,011,649
BlackRock, Inc. 2.1% 666,188 +9.6% 0% $14,975,907
Ikarian Capital, LLC 1.6% 515,000 0% 1.7% $11,577,200
Point72 Asset Management, L.P. 1.6% 503,087 -69% 0.02% $11,309,396
Affinity Asset Advisors, LLC 1.6% 500,000 0.66% $11,240,000
Integral Health Asset Management, LLC 1.6% 500,000 +33% 0.59% $11,240,000
Venrock Adviser, LLC 1.6% 500,000 0.42% $11,240,000
Driehaus Capital Management LLC 1.5% 486,726 +45% 0.08% $10,942,410
NORTHERN TRUST CORP 1.5% 473,403 -0.2% 0% $10,642,099
JENNISON ASSOCIATES LLC 1.2% 386,426 0.01% $8,686,856
ADAGE CAPITAL PARTNERS GP, L.L.C. 1.2% 385,000 0.01% $8,654,800
PRICE T ROWE ASSOCIATES INC /MD/ 1.2% 371,208 +1128% 0% $8,346,000
GEODE CAPITAL MANAGEMENT, LLC 0.92% 292,899 +1.9% 0% $6,587,938
SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.75% 238,498 +102% 0.01% $5,361,435
ALKEON CAPITAL MANAGEMENT LLC 0.72% 227,101 -52% 0.02% $5,105,230

Institutional Holders of Alto Neuroscience, Inc. - Common Stock, par value $0.0001 per share (ANRO) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2026 Q1 26,830,701 $602,479,913 +$54,953,807 $22.48 110
2025 Q4 24,487,002 $435,860,904 +$135,656,607 $17.80 96
2025 Q3 16,755,091 $67,358,617 -$1,672,076 $4.02 74
2025 Q2 17,296,212 $38,050,471 -$7,942,231 $2.20 78
2025 Q1 20,845,367 $45,026,701 -$4,167,716 $2.16 83
2024 Q4 22,530,140 $95,292,066 -$45,543,045 $4.23 77
2024 Q3 22,939,574 $265,498,730 +$37,026,413 $11.44 75
2024 Q2 18,600,674 $198,841,035 +$25,849,471 $10.69 58
2024 Q1 15,971,812 $245,167,778 +$245,167,778 $15.35 52
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