Latest Period
Q4 2025
Security Snapshot
Alto Neuroscience, Inc. - Common Stock, $0.0001 par value per share (ANRO) Institutional Ownership
CUSIP: 02157Q109
13F Institutional Holders and Ownership History from Q1 2024 to Q1 2026
Institutions Reporting
96
Shares (Excl. Options)
24,487,002
Price
$17.80
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- Type / Class
- Equity / Common Stock, $0.0001 par value per share
- Symbol
- ANRO on NYSE
- Shares outstanding
- 31,093,117
- Price per share
- $21.68
- All holders as of 31 Dec 2025
- Q4 2025
- Total 13F shares
- 24,487,002
- Total reported value
- $435,860,904
- % of total 13F portfolios
- 0%
- Share change
- +7,554,448
- Value change
- +$135,656,607
- Number of holders
- 96
- Price from insider filings
- $21.68
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors
Quick Takeaways
- ANRO - Alto Neuroscience, Inc. - Common Stock, $0.0001 par value per share is tracked under CUSIP 02157Q109.
- 96 institutions reported positions in Q4 2025.
- 8 significant owners is listed from Schedule 13D/13G reporting.
What Changed
- Holder count moved from 96 to 10 between Q4 2025 and Q1 2026.
- Reported value moved from $435,860,904 to $2,310,854.
Why This Matters
- You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
- 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.
Source Evidence
Source: SEC Form 13F
Open SEC Evidence
Latest holder context comes from 96 institutions filings for Q4 2025.
Investment Quick Answers
What is CUSIP 02157Q109?
CUSIP 02157Q109 identifies ANRO - Alto Neuroscience, Inc. - Common Stock, $0.0001 par value per share in SEC 13F datasets.
Where can I see the latest institutional holders?
Review the Q4 2025 holders report and the ownership history table below.
Next ownership checks
Use the next link that matches the question you still need to answer about this security.
- Latest 13F filings when you want to inspect fresh institutional portfolio moves.
- Latest Schedule 13D/13G reports when you need large-owner changes outside the 13F cycle.
- All institutional ownership pages to compare this security with other holder-history pages.
Recent Quarterly Holder Reports
Open recent reporting periods for CUSIP 02157Q109:
Significant Owners of Alto Neuroscience, Inc. - Common Stock, $0.0001 par value per share (ANRO) based on Schedule 13D/G filings
| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| PERCEPTIVE ADVISORS LLC | 10% | +38% | $53,623,911 | +$20,798,926 | 3,249,934 | +63% | Perceptive Advisors LLC | 31 Dec 2025 |
| Commodore Capital LP | 9.9% | +1% | $53,552,862 | +$913,456 | 3,245,628 | +1.7% | Commodore Capital LP | 31 Dec 2025 |
| Point72 Asset Management, L.P. | 8.9% | +27% | $46,600,538 | +$15,121,326 | 2,824,275 | +48% | Steven A. Cohen | 31 Dec 2025 |
| Vestal Point Capital, LP | 8% | $41,002,500 | 2,485,000 | Vestal Point Capital, LP | 31 Dec 2025 | |||
| ARMISTICE CAPITAL, LLC | 4.9% | -16% | $23,546,880 | -$981,120 | 1,536,000 | -4% | Armistice Capital, LLC | 31 Dec 2025 |
| FMR LLC | 4.7% | $2,885,445 | 1,265,546 | FMR LLC | 31 Dec 2024 | |||
| K2 HealthVentures Equity Trust LLC | 2.4% | -53% | $13,018,418 | -$13,676,190 | 788,995 | -51% | K2 HealthVentures Equity Trust LLC | 31 Dec 2025 |
| BlackRock, Inc. | 2.1% | $1,234,213 | 561,363 | BlackRock, Inc. | 30 Jun 2025 |
As of 31 Dec 2025, 96 institutional investors reported holding 24,487,002 shares of Alto Neuroscience, Inc. - Common Stock, $0.0001 par value per share (ANRO). This represents 79% of the company’s total 31,093,117 outstanding shares.
Top 25 Institutional Shareholders
The largest institutional shareholders of Alto Neuroscience, Inc. - Common Stock, $0.0001 par value per share (ANRO) together control 72% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| Alpha Wave Global, LP | 12% | 3,707,757 | 0% | 8.1% | $65,998,075 |
| Vestal Point Capital, LP | 8% | 2,485,000 | +162% | 1.6% | $44,233,000 |
| Commodore Capital LP | 5.9% | 1,823,196 | 2.2% | $32,452,889 | |
| PERCEPTIVE ADVISORS LLC | 5.7% | 1,784,393 | +1049% | 0.58% | $31,762,195 |
| Point72 Asset Management, L.P. | 5.2% | 1,606,954 | +21% | 0.04% | $28,603,781 |
| ARMISTICE CAPITAL, LLC | 4.9% | 1,536,000 | -6.1% | 0.67% | $27,340,800 |
| VANGUARD GROUP INC | 4.4% | 1,365,847 | +24% | 0% | $24,312,077 |
| FRANKLIN RESOURCES INC | 3.6% | 1,119,578 | -3.7% | 0% | $19,928,488 |
| Vivo Capital, LLC | 3.3% | 1,035,551 | 1.2% | $18,432,808 | |
| 72 Investment Holdings, LLC | 2.1% | 667,778 | 0% | 24% | $11,886,448 |
| MILLENNIUM MANAGEMENT LLC | 2% | 629,985 | +100% | 0.01% | $11,213,733 |
| BlackRock, Inc. | 2% | 607,874 | +65% | 0% | $10,820,158 |
| Ikarian Capital, LLC | 1.7% | 515,000 | +368% | 1.2% | $9,167,001 |
| ALKEON CAPITAL MANAGEMENT LLC | 1.5% | 477,101 | 0% | 0.04% | $8,492,398 |
| NORTHERN TRUST CORP | 1.5% | 474,373 | +2.8% | 0% | $8,443,839 |
| Integral Health Asset Management, LLC | 1.2% | 375,000 | -6.2% | 0.34% | $6,675,000 |
| Driehaus Capital Management LLC | 1.1% | 336,762 | 0.04% | $5,994,364 | |
| GEODE CAPITAL MANAGEMENT, LLC | 0.92% | 287,435 | +21% | 0% | $5,118,477 |
| Peapod Lane Capital LLC | 0.82% | 253,992 | -9.9% | 3.8% | $4,521,058 |
| AWM Investment Company, Inc. | 0.72% | 225,000 | -20% | 0.39% | $4,005,000 |
| Spruce Street Capital LP | 0.72% | 222,844 | 0% | 1.3% | $3,966,623 |
| JANE STREET GROUP, LLC | 0.62% | 194,041 | +301% | 0% | $3,453,929 |
| MARSHALL WACE, LLP | 0.62% | 193,109 | -77% | 0% | $3,437,340 |
| TWO SIGMA ADVISERS, LP | 0.51% | 160,100 | +6.8% | 0.01% | $2,849,780 |
| GOLDMAN SACHS GROUP INC | 0.5% | 156,319 | +73% | 0% | $2,782,478 |
Institutional Holders of Alto Neuroscience, Inc. - Common Stock, $0.0001 par value per share (ANRO) across Reporting Periods
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2026 Q1 | 102,790 | $2,310,854 | -$4,365,462 | $22.48 | 10 |
| 2025 Q4 | 24,487,002 | $435,860,904 | +$135,656,607 | $17.80 | 96 |
| 2025 Q3 | 16,755,091 | $67,358,617 | -$1,672,076 | $4.02 | 74 |
| 2025 Q2 | 17,296,212 | $38,050,471 | -$7,942,231 | $2.20 | 78 |
| 2025 Q1 | 20,845,367 | $45,026,701 | -$4,167,716 | $2.16 | 83 |
| 2024 Q4 | 22,530,140 | $95,292,066 | -$45,543,045 | $4.23 | 77 |
| 2024 Q3 | 22,939,574 | $265,498,730 | +$37,026,413 | $11.44 | 75 |
| 2024 Q2 | 18,600,674 | $198,841,035 | +$25,849,471 | $10.69 | 58 |
| 2024 Q1 | 15,971,812 | $245,167,778 | +$245,167,778 | $15.35 | 52 |