Praxis Precision Medicines, Inc. - COMMON STOCK (PRAX)

Historical Holders from Q4 2023 to Q4 2025

Type / Class
Equity / COMMON STOCK
Symbol
PRAX on Nasdaq
Shares outstanding
20,907,188
Price per share
$294.74
All holders as of 30 Sep 2025
Q3 2025
Total 13F shares as of 30 Sep 2025
24,666,142
Total reported value
$1,307,300,498
% of total 13F portfolios
0%
Share change
+512,177
Value change
+$38,898,739
Avg buy value change
+0%
Avg sell value change
-0%
Number of holders
149
Price from insider filings
$292.63
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of Praxis Precision Medicines, Inc. - COMMON STOCK (PRAX) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
JANUS HENDERSON GROUP PLC 12% -0.83% $146,484,527 +$12,214,062 2,763,859 +9.1% JANUS HENDERSON GROUP PLC 30 Sep 2025
Point72 Asset Management, L.P. 9.6% +33% $109,866,297 +$28,721,283 2,072,949 +35% Steven A. Cohen 30 Sep 2025
PERCEPTIVE ADVISORS LLC 6.7% +38% $57,294,886 +$16,047,116 1,362,503 +39% Perceptive Advisors LLC 15 Jul 2025
Adage Capital Management, L.P. 5.3% -54% $69,174,275 -$56,652,230 1,305,175 -45% Adage Capital Management, L.P. 31 Oct 2025
Venrock Healthcare Capital Partners III, L.P. 4.9% -20% $37,813,688 -$6,466,960 1,016,497 -15% Venrock Healthcare Capital Partners III, L.P. 31 Mar 2025
PRICE T ROWE ASSOCIATES INC /MD/ 4.8% $53,187,885 1,003,545 T. Rowe Price Associates, Inc. 30 Sep 2025
Cormorant Asset Management, LP 4% -46% $53,000,000 -$33,125,000 1,000,000 -38% Cormorant Asset Management, LP 30 Sep 2025
Soleus Capital Master Fund, L.P. 4.6% -8% $40,651,514 -$2,144,555 966,740 -5% Soleus Capital Master Fund, L.P. 30 Jun 2025
Capital Research Global Investors 4.2% $31,759,351 853,746 Capital Research Global Investors 31 Mar 2025
MORGAN STANLEY 2.9% -55% $32,752,940 -$28,575,480 617,980 -47% Morgan Stanley 30 Sep 2025
As of 30 Sep 2025, Praxis Precision Medicines, Inc. - COMMON STOCK (PRAX) has 149 institutional shareholders filing 13F forms. They hold 24,666,142 shares. .

Top 25 institutional shareholders own 103% of the company.

Filer Ownership Nb Shares Share Change % Portfolio % Holdings Value
JANUS HENDERSON GROUP PLC 13% 2,763,859 +9.1% 0.07% $146,475,065
ADAGE CAPITAL PARTNERS GP, L.L.C. 11% 2,374,085 +20% 0.2% $125,826,505
BlackRock, Inc. 8.6% 1,801,080 +13% 0% $95,457,240
PERCEPTIVE ADVISORS LLC 7.5% 1,564,554 +108% 2.4% $82,921,362
Point72 Asset Management, L.P. 7.2% 1,495,986 +57% 0.17% $79,287,258
VANGUARD GROUP INC 6.1% 1,267,286 +4.2% 0% $67,166,158
PRICE T ROWE ASSOCIATES INC /MD/ 4.8% 1,003,490 -32% 0.01% $53,186,000
Cormorant Asset Management, LP 4.8% 1,000,000 -38% 3.7% $53,000,000
STATE STREET CORP 4.3% 907,108 +30% 0% $48,076,724
Soleus Capital Management, L.P. 4.1% 859,166 -11% 2.4% $45,535,798
DEERFIELD MANAGEMENT COMPANY, L.P. 4% 840,851 +22% 0.68% $44,565,103
BAKER BROS. ADVISORS LP 3.3% 689,488 0% 0.26% $36,542,864
MORGAN STANLEY 3.1% 643,495 -48% 0% $34,105,272
GOLDMAN SACHS GROUP INC 2.8% 593,021 +162% 0% $31,430,113
Driehaus Capital Management LLC 2.4% 500,551 -5.7% 0.19% $26,529,203
BANK OF AMERICA CORP /DE/ 2.3% 482,861 +6.5% 0% $25,591,633
GEODE CAPITAL MANAGEMENT, LLC 2.2% 457,032 +1.2% 0% $24,226,192
Woodline Partners LP 2% 417,669 +809% 0.1% $22,136,457
Assenagon Asset Management S.A. 2% 409,779 -32% 0.03% $21,718,287
CIBC Asset Management Inc 1.9% 388,759 0% 0.06% $20,604,227
FRANKLIN RESOURCES INC 1.5% 314,157 +0% 0% $16,650,321
Vivo Capital, LLC 0.95% 198,895 +19% 0.85% $10,541,435
Sofinnova Investments, Inc. 0.83% 172,833 +1000% 0.56% $9,160,149
5AM Venture Management, LLC 0.81% 170,000 0% 3.3% $9,010,000
NORTHERN TRUST CORP 0.81% 168,353 -21% 0% $8,922,709

Institutional Holders of Praxis Precision Medicines, Inc. - COMMON STOCK (PRAX) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (% of par) Investors
2025 Q4 450,236 $132,702,474 -$1,069,287 29,473.97% 4
2025 Q3 24,666,142 $1,307,300,498 +$38,898,739 5,300% 149
2025 Q2 24,151,627 $1,015,573,040 +$43,479,424 4,205% 141
2025 Q1 23,362,159 $886,031,367 +$1,335,704 3,787% 147
2024 Q4 21,720,756 $1,671,718,000 +$223,523,316 7,696% 160
2024 Q3 18,868,572 $1,091,231,093 +$44,014,289 5,754% 132
2024 Q2 18,424,832 $762,133,327 +$67,529,667 4,136% 113
2024 Q1 15,918,361 $971,295,549 +$514,747,070 6,102% 110
2023 Q4 7,555,380 $168,332,336 +$168,332,336 2,228% 57