Amylyx Pharmaceuticals, Inc. - Common Stock, $0.0001 par value per share (AMLX)

Historical Holders from Q1 2022 to Q3 2025

Symbol
AMLX on Nasdaq
Type / Class
Equity / Common Stock, $0.0001 par value per share
Shares outstanding
110,784,314
All holders as of 30 Sep 2025
Q3 2025
Total 13F shares, excl. options
109,720,607
Holdings value
$1,491,120,900
% of all portfolios
0.01%
Number of holders
167
Number of buys
99
Number of sells
-67
Average buys %
+0%
Average sells %
-0%
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of Amylyx Pharmaceuticals, Inc. - Common Stock, $0.0001 par value per share (AMLX)

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
FMR LLC 10.7% $154,666,182 11,379,207 FMR LLC 30 Sep 2025
PERCEPTIVE ADVISORS LLC 8.2% -6.7% $121,662,640 +$14,650,251 8,952,365 +14% Perceptive Advisors LLC 30 Sep 2025
Adage Capital Management, L.P. 6.39% -35% $92,640,693 -$26,951,307 6,816,828 -23% Adage Capital Management, L.P. 30 Sep 2025
Commodore Capital LP 5.1% $89,213,500 5,650,000 Commodore Capital LP 10 Nov 2025
VANGUARD GROUP INC 4.94% -2% $71,672,372 +$10,542,372 5,273,750 +17% The Vanguard Group 30 Sep 2025
BlackRock, Inc. 5.5% $31,547,244 4,917,501 BlackRock, Inc. 30 Jun 2025
Point72 Asset Management, L.P. 2.6% -54% $38,074,233 -$26,039,432 2,801,636 -41% Point72 Asset Management, L.P. 30 Sep 2025
Panacea Innovation Ltd 2.6% $11,792,000 2,200,000 Panacea Venture Healthcare Fund II, L.P. 31 Dec 2024

Institutional Holders of Amylyx Pharmaceuticals, Inc. - Common Stock, $0.0001 par value per share (AMLX)

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price Investors
2025 Q3 109,720,607 $1,491,120,900 +$396,029,872 $13.59 167
2025 Q2 81,689,919 $523,631,692 +$57,316,535 $6.41 130
2025 Q1 73,877,500 $261,528,744 +$85,099,354 $3.54 134
2024 Q4 49,784,011 $188,180,501 +$19,458,443 $3.78 120
2024 Q3 43,406,257 $140,608,833 +$5,128,506 $3.24 107
2024 Q2 43,632,024 $82,904,189 -$16,885,307 $1.9 115
2024 Q1 49,485,594 $140,539,742 -$234,955,037 $2.84 138
2023 Q4 60,281,638 $887,348,868 -$11,902,243 $14.72 177
2023 Q3 58,927,724 $1,078,966,869 +$84,065,478 $18.31 168
2023 Q2 54,545,075 $1,176,653,052 +$56,163,167 $21.57 153
2023 Q1 51,372,917 $1,507,231,117 +$73,671,274 $29.34 145
2022 Q4 48,572,530 $1,794,757,212 +$422,522,242 $36.95 131
2022 Q3 36,858,311 $1,037,561,470 +$315,174,073 $28.15 90
2022 Q2 26,621,859 $512,910,346 +$65,322,870 $19.26 74
2022 Q1 23,420,880 $299,935,403 +$299,912,422 $12.85 72