| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| PERCEPTIVE ADVISORS LLC | 10% | $47,123,411 | 6,770,605 | Perceptive Advisors LLC | 11 Nov 2025 | |||
| Venrock Healthcare Capital Partners III, L.P. | 7.1% | -28% | $39,984,449 | -$2,304,500 | 4,771,414 | -5.4% | Venrock Healthcare Capital Partners III, L.P. | 31 Dec 2025 |
| Deep Track Capital, LP | 6.7% | +58% | $30,048,631 | +$14,462,734 | 4,317,332 | +93% | Deep Track Capital, LP | 11 Nov 2025 |
| Invus Global Management, LLC | 6.3% | $38,328,368 | 4,244,559 | Raymond Debbane | 21 Jan 2026 | |||
| Cormorant Asset Management, LP | 6% | $33,520,000 | 4,000,000 | Cormorant Asset Management, LP | 31 Dec 2025 | |||
| Fonds de solidarite des travailleurs et des travailleuses du Quebec | 4.5% | $8,119,004 | 2,029,751 | Fonds de solidarite des travailleurs et des travailleuses du Quebec | 30 Sep 2024 | |||
| Adage Capital Management, L.P. | 3% | $6,115,072 | 1,528,768 | Adage Capital Management, L.P. | 31 Dec 2024 | |||
| Kynam Capital Management, LP | 2.2% | -76% | $12,510,485 | -$29,339,989 | 1,492,898 | -70% | Kynam Capital Management, LP | 31 Dec 2025 |
| BIOTECHNOLOGY VALUE FUND L P | 1.8% | -68% | $3,781,608 | -$8,424,148 | 945,402 | -69% | BVF PARTNERS L P/IL | 27 Jan 2025 |
As of 31 Dec 2025, 57 institutional investors reported holding 58,699,543 shares of enGene Holdings Inc. - Common Shares (ENGN). This represents 87% of the company’s total 67,203,014 outstanding shares.
The largest institutional shareholders of enGene Holdings Inc. - Common Shares (ENGN) together control 84% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| FCPM III SERVICES B.V. | 14% | 9,632,561 | 0% | 11% | $86,982,026 |
| PERCEPTIVE ADVISORS LLC | 8.7% | 5,869,076 | +180% | 0.97% | $52,997,756 |
| VR ADVISER, LLC | 7.1% | 4,771,414 | -5.4% | 2.1% | $43,085,868 |
| Deep Track Capital, LP | 6.5% | 4,377,572 | +95% | 0.9% | $39,529,475 |
| Cormorant Asset Management, LP | 6% | 4,000,000 | +72% | 2% | $36,120,000 |
| Blue Owl Capital Holdings LP | 5% | 3,360,937 | +2.5% | 9.4% | $30,349,261 |
| Siren, L.L.C. | 5% | 3,336,264 | 0.9% | $30,126,464 | |
| BRAIDWELL LP | 4.7% | 3,131,319 | +38% | 0.9% | $28,275,811 |
| Nextech Invest, Ltd. | 3.2% | 2,124,943 | 1.9% | $19,188,235 | |
| JANUS HENDERSON GROUP PLC | 2.8% | 1,900,000 | 0.01% | $17,109,500 | |
| MPM BIOIMPACT LLC | 2.7% | 1,840,898 | +247% | 1.9% | $16,623,309 |
| MILLENNIUM MANAGEMENT LLC | 2.2% | 1,499,520 | +7214% | 0.01% | $13,540,666 |
| Kynam Capital Management, LP | 2.2% | 1,492,898 | -70% | 0.88% | $13,480,869 |
| FRANKLIN RESOURCES INC | 2.1% | 1,388,000 | +34% | 0% | $12,533,640 |
| Polar Capital Holdings Plc | 1.7% | 1,142,982 | 0.05% | $10,321,127 | |
| Vestal Point Capital, LP | 1.6% | 1,055,000 | +185% | 0.35% | $9,526,650 |
| EVENTIDE ASSET MANAGEMENT, LLC | 1.4% | 950,000 | 0.13% | $8,578,500 | |
| Omega Fund Management, LLC | 1.3% | 876,357 | +66% | 2.8% | $7,913,504 |
| SR One Capital Management, LP | 1.1% | 747,750 | 0% | 0.96% | $6,752,183 |
| MORGAN STANLEY | 1.1% | 718,485 | +65% | 0% | $6,487,919 |
| Affinity Asset Advisors, LLC | 0.96% | 643,370 | +736% | 0.42% | $5,809,631 |
| Point72 Asset Management, L.P. | 0.84% | 561,797 | -54% | 0.01% | $5,073,027 |
| Eversept Partners, LP | 0.68% | 455,835 | 0.23% | $4,116,190 | |
| Privium Fund Management B.V. | 0.52% | 352,087 | 0.59% | $3,179,346 | |
| MARSHALL WACE, LLP | 0.51% | 343,928 | 0% | 0% | $3,105,670 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2025 Q4 | 58,699,543 | $530,008,548 | +$166,162,647 | $9.03 | 57 |
| 2025 Q3 | 40,858,497 | $279,063,473 | +$5,402,489 | $6.83 | 37 |
| 2025 Q2 | 40,420,485 | $147,130,372 | -$1,920,470 | $3.64 | 37 |
| 2025 Q1 | 40,941,351 | $183,416,794 | -$6,334,706 | $4.48 | 31 |
| 2024 Q4 | 41,304,528 | $274,675,480 | +$47,869,542 | $6.65 | 34 |
| 2024 Q3 | 34,293,391 | $227,693,885 | +$6,723,051 | $6.60 | 30 |
| 2024 Q2 | 32,608,601 | $307,109,469 | -$7,912,013 | $9.43 | 30 |
| 2024 Q1 | 31,657,538 | $536,055,932 | +$295,887,521 | $16.95 | 31 |
| 2023 Q4 | 14,187,864 | $130,941,207 | +$50,843,719 | $9.23 | 11 |