Security Snapshot

enGene Therapeutics Inc. - Common Shares (ENGN) Institutional Ownership

CUSIP: 29286M105

13F Institutional Holders and Ownership History from Q4 2023 to Q1 2026

Latest Period

Q4 2025

Institutions Reporting

57

Shares (Excl. Options)

58,699,543

Price

$9.03

Save this security page for your next review

Keep this CUSIP in your watchlists so you can revisit quarter changes from one place. If you create an account from here, we will bring you back after verification.

Type / Class
Equity / Common Shares
Symbol
ENGN on Nasdaq
Shares outstanding
67,348,192
Price per share
$6.76
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
58,699,543
Total reported value
$530,008,548
% of total 13F portfolios
0%
Share change
+17,595,169
Value change
+$166,162,647
Number of holders
57
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Quick Takeaways

  • ENGN - enGene Therapeutics Inc. - Common Shares is tracked under CUSIP 29286M105.
  • 57 institutions reported positions in Q4 2025.
  • 9 significant owners is listed from Schedule 13D/13G reporting.

What Changed

  • Holder count moved from 57 to 4 between Q4 2025 and Q1 2026.
  • Reported value moved from $530,008,548 to $2,812,373.

Why This Matters

  • You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
  • 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.

Source Evidence

Source: SEC Form 13F

Latest holder context comes from 57 institutions filings for Q4 2025.

Open SEC Evidence

Investment Quick Answers

What is CUSIP 29286M105?
CUSIP 29286M105 identifies ENGN - enGene Therapeutics Inc. - Common Shares in SEC 13F datasets.

Where can I see the latest institutional holders?
Review the Q4 2025 holders report and the ownership history table below.

Significant Owners of enGene Therapeutics Inc. - Common Shares (ENGN) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
PERCEPTIVE ADVISORS LLC 10% $47,123,411 6,770,605 Perceptive Advisors LLC 11 Nov 2025
Invus Global Management, LLC 7.8% +25% $35,511,355 +$6,818,136 5,253,159 +24% Raymond Debbane 31 Mar 2026
Venrock Healthcare Capital Partners III, L.P. 7.1% -28% $39,984,449 -$2,304,500 4,771,414 -5.4% Venrock Healthcare Capital Partners III, L.P. 31 Dec 2025
Deep Track Capital, LP 6.7% +58% $30,048,631 +$14,462,734 4,317,332 +93% Deep Track Capital, LP 11 Nov 2025
Cormorant Asset Management, LP 6% $33,520,000 4,000,000 Cormorant Asset Management, LP 31 Dec 2025
Fonds de solidarite des travailleurs et des travailleuses du Quebec 4.5% $8,119,004 2,029,751 Fonds de solidarite des travailleurs et des travailleuses du Quebec 30 Sep 2024
Adage Capital Management, L.P. 3% $6,115,072 1,528,768 Adage Capital Management, L.P. 31 Dec 2024
Kynam Capital Management, LP 2.2% -76% $12,510,485 -$29,339,989 1,492,898 -70% Kynam Capital Management, LP 31 Dec 2025
BIOTECHNOLOGY VALUE FUND L P 1.8% -68% $3,781,608 -$8,424,148 945,402 -69% BVF PARTNERS L P/IL 27 Jan 2025

As of 31 Dec 2025, 57 institutional investors reported holding 58,699,543 shares of enGene Therapeutics Inc. - Common Shares (ENGN). This represents 87% of the company’s total 67,348,192 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of enGene Therapeutics Inc. - Common Shares (ENGN) together control 84% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
FCPM III SERVICES B.V. 14% 9,632,561 0% 11% $86,982,026
PERCEPTIVE ADVISORS LLC 8.7% 5,869,076 +180% 0.97% $52,997,756
VR ADVISER, LLC 7.1% 4,771,414 -5.4% 2.1% $43,085,868
Deep Track Capital, LP 6.5% 4,377,572 +95% 0.9% $39,529,475
Cormorant Asset Management, LP 5.9% 4,000,000 +72% 2% $36,120,000
Blue Owl Capital Holdings LP 5% 3,360,937 +2.5% 9.4% $30,349,261
Siren, L.L.C. 5% 3,336,264 0.9% $30,126,464
BRAIDWELL LP 4.6% 3,131,319 +38% 0.9% $28,275,811
Nextech Invest, Ltd. 3.2% 2,124,943 1.9% $19,188,235
JANUS HENDERSON GROUP PLC 2.8% 1,900,000 0.01% $17,109,500
MPM BIOIMPACT LLC 2.7% 1,840,898 +247% 1.9% $16,623,309
MILLENNIUM MANAGEMENT LLC 2.2% 1,499,520 +7214% 0.01% $13,540,666
Kynam Capital Management, LP 2.2% 1,492,898 -70% 0.88% $13,480,869
FRANKLIN RESOURCES INC 2.1% 1,388,000 +34% 0% $12,533,640
Polar Capital Holdings Plc 1.7% 1,142,982 0.05% $10,321,127
Vestal Point Capital, LP 1.6% 1,055,000 +185% 0.35% $9,526,650
EVENTIDE ASSET MANAGEMENT, LLC 1.4% 950,000 0.13% $8,578,500
Omega Fund Management, LLC 1.3% 876,357 +66% 2.8% $7,913,504
SR One Capital Management, LP 1.1% 747,750 0% 0.96% $6,752,183
MORGAN STANLEY 1.1% 718,485 +65% 0% $6,487,919
Affinity Asset Advisors, LLC 0.96% 643,370 +736% 0.42% $5,809,631
Point72 Asset Management, L.P. 0.83% 561,797 -54% 0.01% $5,073,027
Eversept Partners, LP 0.68% 455,835 0.23% $4,116,190
Privium Fund Management B.V. 0.52% 352,087 0.59% $3,179,346
MARSHALL WACE, LLP 0.51% 343,928 0% 0% $3,105,670

Institutional Holders of enGene Therapeutics Inc. - Common Shares (ENGN) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2026 Q1 412,977 $2,812,373 +$328,622 $6.81 4
2025 Q4 58,699,543 $530,008,548 +$166,162,647 $9.03 57
2025 Q3 40,858,497 $279,063,473 +$5,402,489 $6.83 37
2025 Q2 40,420,485 $147,130,372 -$1,920,470 $3.64 37
2025 Q1 40,941,351 $183,416,794 -$6,334,706 $4.48 31
2024 Q4 41,304,528 $274,675,480 +$47,869,542 $6.65 34
2024 Q3 34,293,391 $227,693,885 +$6,723,051 $6.60 30
2024 Q2 32,608,601 $307,109,469 -$7,912,013 $9.43 30
2024 Q1 31,657,538 $536,055,932 +$295,887,521 $16.95 31
2023 Q4 14,187,864 $130,941,207 +$50,843,719 $9.23 11
We use cookies and similar technologies to provide certain features, enhance the user experience and, if you allow them, measure engagement and deliver advertising. Analytics and marketing storage stay off until you grant consent. By clicking on "Agree and continue", you declare your consent to the use of the selected optional cookies. Here you can make detailed settings or revoke your consent (in part if necessary) with effect for the future. For further information, please refer to our Privacy Policy .