ORBIMED ADVISORS LLC

Insider Reports History

Location
New York, NY
Signature
/s/ Carl L. Gordon, Member of OrbiMed Advisors LLC
All insider transactions
Transactions in reports broken out by “transaction date” reported in original SEC filing, see here for transactions aggregated across transaction date

Holdings reported by ORBIMED ADVISORS LLC:

Form 4 holding Director, 10%+ Owner

Enliven Therapeutics, Inc.

Security class
Common Stock
Shares / value
7,663,349
Estimated value
$169,666,547
Report date
16 May 2024
Price
$22.14
Ownership
Indirect
Form 4 holding Director

Verona Pharma plc

Security class
Ordinary Shares
Shares / value
3,777,778
Estimated value
$75,555,560
Report date
15 May 2023
Price
$20.00
Ownership
Indirect
Form 4 holding Director, 10%+ Owner

Third Harmonic Bio, Inc.

Security class
Common Stock
Shares / value
5,779,071
Estimated value
$59,522,120
Report date
19 Sep 2022
Price
$10.30
Ownership
Indirect
Form 4 holding 10%+ Owner

89bio, Inc.

Security class
Common Stock
Shares / value
1,829,436
Estimated value
$21,093,397
Report date
26 Jan 2022
Price
$11.53
Ownership
Indirect
Form 4 holding 10%+ Owner

TELA Bio, Inc.

Security class
Common Stock
Shares / value
2,407,242
Estimated value
$10,928,879
Report date
02 Jul 2024
Price
$4.54
Ownership
Indirect
Form 4 holding Director

Disc Medicine, Inc.

Security class
Common Stock
Shares / value
186,541
Estimated value
$10,093,734
Report date
24 Mar 2025
Price
$54.11
Ownership
Indirect
Form 4 holding Director, 10%+ Owner

Edgewise Therapeutics, Inc.

Security class
Common Stock
Shares / value
443,792
Estimated value
$8,933,533
Report date
03 Apr 2025
Price
$20.13
Ownership
Indirect
Form 4 holding Director, 10%+ Owner

MBX Biosciences, Inc.

Security class
Common Stock
Shares / value
747,887
Estimated value
$8,107,095
Report date
18 Feb 2025
Price
$10.84
Ownership
Indirect
Form 4 holding Director, 10%+ Owner

Terns Pharmaceuticals, Inc.

Security class
Common Stock
Shares / value
755,635
Estimated value
$7,556,350
Report date
16 Jul 2024
Price
$10.00
Ownership
Indirect
Form 4 holding Director, 10%+ Owner

ArriVent Biopharma, Inc.

Security class
Common Stock
Shares / value
1,513,664
Estimated value
$5,524,874
Report date
30 Jan 2024
Price
$3.65
Ownership
Indirect
Form 4 holding Director, 10%+ Owner

Acutus Medical, Inc.

Security class
Common Stock
Shares / value
1,677,361
Estimated value
$2,616,683
Report date
19 Jul 2021
Price
$1.56
Ownership
Indirect
Form 4 holding Director

Janux Therapeutics, Inc.

Security class
Common Stock
Shares / value
231,098
Estimated value
$1,356,545
Report date
29 Dec 2021
Price
$5.87
Ownership
Indirect
Form 4 holding Director, 10%+ Owner

Homology Medicines, Inc.

Security class
Common Stock
Shares / value
2,252,987
Estimated value
$1,286,681
Report date
25 Mar 2024
Price
$0.5711
Ownership
By OrbiMed Private Investments VII, LP
Form 4 holding 10%+ Owner

Galecto, Inc.

Security class
Common Stock
Shares / value
1,510,375
Estimated value
$1,132,781
Report date
15 Aug 2023
Price
$0.7500
Ownership
Indirect
Form 4 holding 10%+ Owner

scPharmaceuticals Inc.

Security class
Common Stock
Shares / value
252,858
Estimated value
$1,011,432
Report date
13 Aug 2024
Price
$4.00
Ownership
Indirect
Form 4 holding Director

Repare Therapeutics Inc.

Security class
Common Stock
Shares / value
96,190
Estimated value
$233,261
Report date
07 Sep 2021
Price
$2.42
Ownership
Indirect
Form 4 holding Director, 10%+ Owner

Kinnate Biopharma Inc.

Security class
Common Stock
Shares / value
0
Estimated value
$0
Report date
03 Apr 2024
Price
$2.59
Ownership
Indirect
Form 4 holding Director, 10%+ Owner

Upstream Bio, Inc.

Security class
Common Stock
Shares / value
4,554,873
Estimated value
Report date
15 Oct 2024
Price
Ownership
Indirect
Form 4 holding Director

Shattuck Labs, Inc.

Security class
Common Warrants (right to buy)
Shares / value
3,073,298
Estimated value
Report date
25 Aug 2025
Price
Ownership
Indirect
Underlying class
Common Stock
Underlying amount
Form 4 holding Director

Shattuck Labs, Inc.

Security class
Pre-Funded Warrants (right to buy)
Shares / value
2,022,277
Estimated value
Report date
25 Aug 2025
Price
Ownership
Indirect
Underlying class
Common Stock
Underlying amount
Form 4 holding 10%+ Owner

Traws Pharma, Inc.

Security class
Series C Warrants (right to buy)
Shares / value
1,793,187
Estimated value
Report date
16 Apr 2026
Price
Ownership
Indirect
Underlying class
Common Stock
Underlying amount
Form 4 holding 10%+ Owner

Traws Pharma, Inc.

Security class
Series A Warrants (right to buy)
Shares / value
597,729
Estimated value
Report date
16 Apr 2026
Price
Ownership
Indirect
Underlying class
Common Stock
Underlying amount
Form 4 holding 10%+ Owner

Traws Pharma, Inc.

Security class
Series B Warrants (right to buy)
Shares / value
597,729
Estimated value
Report date
16 Apr 2026
Price
Ownership
Indirect
Underlying class
Common Stock
Underlying amount
Form 4 holding Director

ImageneBio, Inc.

Security class
Pre-Funded Warrants (right to buy)
Shares / value
384,689
Estimated value
Report date
14 Apr 2026
Price
Ownership
Indirect
Underlying class
Common Stock
Underlying amount
Form 4 holding 10%+ Owner

Traws Pharma, Inc.

Security class
Pre-Funded Warrant (right to buy)
Shares / value
96,348
Estimated value
Report date
29 Dec 2024
Price
Ownership
Indirect
Underlying class
Common Stock
Underlying amount
Form 4 holding 10%+ Owner

Traws Pharma, Inc.

Security class
Series A Warrant (right to buy)
Shares / value
96,348
Estimated value
Report date
29 Dec 2024
Price
Ownership
Indirect
Underlying class
Common Stock
Underlying amount
Form 4 holding Director

ALPINE IMMUNE SCIENCES, INC.

Security class
Warrant (Right to Buy)
Shares / value
0
Estimated value
Report date
11 Jan 2024
Price
Ownership
Indirect
Underlying class
Common Stock
Underlying amount
Form 4 holding Director, 10%+ Owner

ArriVent Biopharma, Inc.

Security class
Series A Preferred Stock
Shares / value
0
Estimated value
Report date
30 Jan 2024
Price
Ownership
Indirect
Underlying class
Common Stock
Underlying amount
Form 4 holding Director, 10%+ Owner

ArriVent Biopharma, Inc.

Security class
Series B Preferred Stock
Shares / value
0
Estimated value
Report date
30 Jan 2024
Price
Ownership
Indirect
Underlying class
Common Stock
Underlying amount
Form 4 holding Director, 10%+ Owner

MBX Biosciences, Inc.

Security class
Series A Convertible Preferred Stock
Shares / value
0
Estimated value
Report date
16 Sep 2024
Price
Ownership
By OrbiMed Private Investments VII, LP
Underlying class
Common Stock
Underlying amount
Form 4 holding Director, 10%+ Owner

MBX Biosciences, Inc.

Security class
Series B Convertible Preferred Stock
Shares / value
0
Estimated value
Report date
16 Sep 2024
Price
Ownership
By OrbiMed Private Investments VII, LP
Underlying class
Common Stock
Underlying amount
Form 4 holding Director, 10%+ Owner

MBX Biosciences, Inc.

Security class
Series C Convertible Preferred Stock
Shares / value
0
Estimated value
Report date
16 Sep 2024
Price
Ownership
By OrbiMed Genesis Master Fund, L.P.
Underlying class
Common Stock
Underlying amount
Form 4 holding Director, 10%+ Owner

Sierra Oncology, Inc.

Security class
Common Stock
Shares / value
0
Estimated value
Report date
01 Jul 2022
Price
$55.00
Ownership
Indirect
Form 4 holding Director, 10%+ Owner

Sierra Oncology, Inc.

Security class
Series A Warrants
Shares / value
0
Estimated value
Report date
01 Jul 2022
Price
Ownership
Indirect
Underlying class
Common Stock
Underlying amount
Form 4 holding Director

Sionna Therapeutics, Inc.

Security class
Series B convertible preferred stock
Shares / value
0
Estimated value
Report date
10 Feb 2025
Price
Ownership
Indirect
Underlying class
Common Stock
Underlying amount
Form 4 holding Director

Sionna Therapeutics, Inc.

Security class
Series C convertible preferred stock
Shares / value
0
Estimated value
Report date
10 Feb 2025
Price
Ownership
Indirect
Underlying class
Common Stock
Underlying amount
Form 4 holding Director, 10%+ Owner

Third Harmonic Bio, Inc.

Security class
Series A-2 Preferred Stock
Shares / value
0
Estimated value
Report date
19 Sep 2022
Price
Ownership
Indirect
Underlying class
Common Stock
Underlying amount
Form 4 holding Director, 10%+ Owner

Third Harmonic Bio, Inc.

Security class
Series A-3 Preferred Stock
Shares / value
0
Estimated value
Report date
19 Sep 2022
Price
Ownership
Indirect
Underlying class
Common Stock
Underlying amount
Form 4 holding Director, 10%+ Owner

Third Harmonic Bio, Inc.

Security class
Series B Preferred Stock
Shares / value
0
Estimated value
Report date
19 Sep 2022
Price
Ownership
Indirect
Underlying class
Common Stock
Underlying amount
Form 4 holding Director, 10%+ Owner

Tricida, Inc.

Security class
Common Stock
Shares / value
0
Estimated value
Report date
25 Nov 2022
Price
Ownership
Indirect
Form 4 holding Director, 10%+ Owner

Upstream Bio, Inc.

Security class
Series A redeemable convertible preferred stock
Shares / value
0
Estimated value
Report date
15 Oct 2024
Price
Ownership
Indirect
Underlying class
Common Stock
Underlying amount
Form 4 holding Director, 10%+ Owner

Upstream Bio, Inc.

Security class
Series B redeemable convertible preferred stock
Shares / value
0
Estimated value
Report date
15 Oct 2024
Price
Ownership
Indirect
Underlying class
Common Stock
Underlying amount
Form 4 holding Director

Venetian-1 Acquisition Corp.

Security class
Simple Agreement for Future Equity
Shares / value
0
Estimated value
Report date
01 Nov 2024
Price
Ownership
Indirect
Underlying class
Common Stock
Underlying amount

Insider Reports Filed by ORBIMED ADVISORS LLC

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