| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| CITADEL ADVISORS LLC | 0% | -103% | $1,250 | -$367,360 | 3,732 | -100% | Kenneth Griffin | 30 Sep 2025 |
As of 31 Dec 2025, 19 institutional investors reported holding 3,417,864 shares of VYNE Therapeutics Inc. - Common Stock, par value $0.0001 per share (VYNE). This represents 18% of the company’s total 18,514,484 outstanding shares.
The largest institutional shareholders of VYNE Therapeutics Inc. - Common Stock, par value $0.0001 per share (VYNE) together control 18% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| Nantahala Capital Management, LLC | 5.4% | 1,000,000 | 0.03% | $580,100 | |
| T3 Companies, LLC | 5.1% | 945,000 | 0% | 0.7% | $548,195 |
| ACADIAN ASSET MANAGEMENT LLC | 3.4% | 638,492 | +43% | 0% | $370,000 |
| VANGUARD GROUP INC | 1.7% | 314,545 | +65% | 0% | $182,436 |
| GEODE CAPITAL MANAGEMENT, LLC | 1.2% | 225,152 | +64% | 0% | $130,614 |
| JANE STREET GROUP, LLC | 0.39% | 72,356 | -51% | 0% | $41,974 |
| UBS Group AG | 0.34% | 62,761 | +1026% | 0% | $36,401 |
| GSA CAPITAL PARTNERS LLP | 0.29% | 53,961 | +50% | 0% | $31,000 |
| BlackRock, Inc. | 0.24% | 44,404 | 0% | 0% | $25,759 |
| FNY Investment Advisers, LLC | 0.14% | 25,000 | 0% | $14,000 | |
| COMMONWEALTH EQUITY SERVICES, LLC | 0.1% | 18,298 | 0% | 0% | $10,610 |
| STATE STREET CORP | 0.09% | 15,765 | 0% | 0% | $9,145 |
| MB, LEVIS & ASSOCIATES, LLC | 0.01% | 1,041 | 0% | 0% | $604 |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 0% | 800 | 0% | $464 | |
| JPMORGAN CHASE & CO | 0% | 146 | 0% | 0% | $85 |
| WELLS FARGO & COMPANY/MN | 0% | 65 | 0% | 0% | $38 |
| MORGAN STANLEY | 0% | 43 | -95% | 0% | $25 |
| Truvestments Capital LLC | 0% | 25 | 0% | 0% | $15 |
| Newbridge Financial Services Group, Inc. | 0% | 10 | 0% | 0% | $6 |
| BlackRock, Inc. | 0% | 1 | 0% | $1 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2025 Q4 | 3,417,864 | $1,981,471 | +$828,610 | $0.58 | 19 |
| 2025 Q3 | 3,924,005 | $1,315,944 | -$9,032,746 | $0.34 | 31 |
| 2025 Q2 | 8,048,768 | $13,279,291 | +$1,503,898 | $1.65 | 44 |
| 2025 Q1 | 7,109,939 | $11,401,092 | -$2,382,241 | $1.58 | 36 |
| 2024 Q4 | 7,028,274 | $23,320,995 | +$606,162 | $3.35 | 34 |
| 2024 Q3 | 7,312,555 | $14,256,902 | -$1,226,342 | $1.88 | 31 |
| 2024 Q2 | 7,942,286 | $16,030,293 | +$243,077 | $1.97 | 30 |
| 2024 Q1 | 6,405,086 | $19,663,149 | +$378,435 | $3.07 | 29 |
| 2023 Q4 | 7,863,834 | $18,322,345 | +$17,207,859 | $2.33 | 32 |
| 2023 Q3 | 360,099 | $1,445,870 | -$33,734 | $4.04 | 20 |
| 2023 Q2 | 375,960 | $1,532,386 | +$198,131 | $4.10 | 19 |
| 2023 Q1 | 335,259 | $1,031,948 | +$1,031,948 | $3.08 | 19 |