13F reference period
Q2 2026
CUSIP: 746964105
13F reference period
Q2 2026
Institutions Reporting
70
Shares (Excl. Options)
22,179,033
Price
$12.74
The headline uses the Q2 2026 reference period after its reporting deadline. Available reports may still be incomplete or amended. Newer periods in the history table contain incoming reports and may be incomplete.
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Latest holder context comes from 70 institutions filings for Q2 2026.
Security key
746964105
13F reference period
Q2 2026
13F holders
70
13D/G owners
11
CIK / CUSIP context first
Broader feeds
Open recent reporting periods for CUSIP 746964105:
13D/G owners
Large-stake holder rows connected to Schedule 13D/G evidence.
| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| ORBIMED ADVISORS LLC | 14% | -21% | $49,329,445 | 4,127,987 | 0% | ORBIMED ADVISORS LLC | 16 Jul 2026 | |
| Boxer Capital Management, LLC | 13% | $37,886,199 | 3,149,310 | Boxer Capital Management, LLC | 30 Jun 2026 | |||
| BIOTECHNOLOGY VALUE FUND L P | 10% | $13,021,382 | 2,367,524 | BVF PARTNERS L P/IL | 28 May 2026 | |||
| RA CAPITAL MANAGEMENT, L.P. | 9.8% | $12,828,514 | 2,332,457 | RA Capital Management, L.P. | 28 May 2026 | |||
| Frazier Life Sciences Public Fund, L.P. | 5.9% | $19,481,788 | 1,755,116 | Frazier Life Sciences Public Fund, L.P. | 02 Oct 2026 | |||
| Point72 Asset Management, L.P. | 5% | -12% | $25,087,206 | +$4,588,747 | 1,173,396 | +22% | Point72 Asset Management, L.P. | 30 Jun 2026 |
| Opaleye Management Inc. | 5.5% | -34% | $19,904,780 | -$6,953,375 | 931,000 | -26% | Opaleye Management Inc. | 30 Jun 2026 |
| Atlas Venture Fund X, L.P. | 3.6% | $4,753,436 | 864,261 | Atlas Venture Fund X, L.P. | 26 May 2026 | |||
| Carlyle Group Inc. | 4.1% | $8,321,572 | 691,735 | The Carlyle Group Inc. | 30 Jun 2026 | |||
| PFIZER INC | 2.3% | $994,442 | 277,777 | Pfizer Inc. (IRS Identification No.: 13-5315170) | 31 Dec 2024 | |||
| BRISTOL MYERS SQUIBB CO | 1.6% | $312,381 | 200,244 | BRISTOL MYERS SQUIBB CO | 31 Dec 2024 |
As of 30 Jun 2026, 70 institutional investors reported holding 22,179,033 shares of Q32 Bio Inc. - Common Stock, $0.00001 par value (QTTB). This represents 75% of the company’s total 29,747,729 outstanding shares.
13F concentration
Largest 13F positions for this security by reported shares and value.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| ORBIMED ADVISORS LLC | 14% | 4,127,987 | +83% | 1% | $52,590,554 |
| Boxer Capital Management, LLC | 11% | 3,149,310 | 3% | $40,122,209 | |
| Atlas Venture Life Science Advisors, LLC | 9.1% | 2,717,106 | +30% | 3.9% | $34,615,930 |
| BVF INC/IL | 7.9% | 2,350,000 | 0.77% | $29,939,000 | |
| RA CAPITAL MANAGEMENT, L.P. | 7.8% | 2,332,457 | 0.26% | $29,715,502 | |
| Point72 Asset Management, L.P. | 3.9% | 1,173,396 | 0.02% | $14,949,065 | |
| Opaleye Management Inc. | 3.1% | 931,000 | -26% | 1.1% | $11,860,940 |
| Logos Global Management LP | 2.7% | 800,000 | 0.44% | $10,192,000 | |
| SummitTX Capital, L.P. | 2.5% | 733,774 | 0.25% | $9,348,281 | |
| VANGUARD CAPITAL MANAGEMENT LLC | 1.7% | 518,803 | +69% | 0% | $6,609,550 |
| Ikarian Capital, LLC | 1.4% | 430,000 | 0.9% | $5,478,200 | |
| Woodline Partners LP | 0.96% | 286,212 | 0.01% | $3,646,341 | |
| AMERICAN CENTURY COMPANIES INC | 0.92% | 272,752 | +1353% | 0% | $3,474,860 |
| Sanofi | 0.82% | 244,083 | 0% | 0.58% | $3,109,617 |
| ACADIAN ASSET MANAGEMENT LLC | 0.73% | 218,234 | +26% | 0% | $2,779,000 |
| ACORN CAPITAL ADVISORS, LLC | 0.73% | 216,171 | -31% | 0.75% | $2,754,019 |
| RENAISSANCE TECHNOLOGIES LLC | 0.6% | 179,600 | -13% | 0% | $2,288,104 |
| JANE STREET GROUP, LLC | 0.55% | 162,747 | +148% | 0% | $2,073,396 |
| MONIMUS CAPITAL MANAGEMENT, LP | 0.44% | 132,036 | -1.7% | 0.43% | $1,682,139 |
| BOOTHBAY FUND MANAGEMENT, LLC | 0.44% | 130,427 | 0.03% | $1,661,640 | |
| GEODE CAPITAL MANAGEMENT, LLC | 0.41% | 122,690 | +3.8% | 0% | $1,563,506 |
| CITADEL ADVISORS LLC | 0.41% | 120,663 | +679% | 0% | $1,537,247 |
| BlackRock, Inc. | 0.4% | 118,507 | +38% | 0% | $1,509,780 |
| MARSHALL WACE, LLP | 0.23% | 67,045 | +28% | 0% | $854,153 |
| VANGUARD FIDUCIARY TRUST CO | 0.22% | 66,217 | +32% | 0% | $843,605 |
Quarter history
Holder count, reported shares/value, and median price by quarter.
| Period | 13F Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2026 Q3 | 362 | $2,995 | +$819 | $8.27 | 3 |
| 2026 Q2 | 22,179,033 | $282,559,680 | +$166,954,159 | $12.74 | 70 |
| 2026 Q1 | 9,428,888 | $60,617,009 | +$9,025,150 | $6.42 | 53 |
| 2025 Q4 | 8,043,846 | $26,659,216 | -$1,063,038 | $3.32 | 51 |
| 2025 Q3 | 8,428,600 | $16,632,224 | -$986,951 | $1.98 | 52 |
| 2025 Q2 | 8,978,370 | $13,355,302 | -$657,201 | $1.49 | 59 |
| 2025 Q1 | 9,406,123 | $15,511,257 | -$5,227,234 | $1.65 | 71 |
| 2024 Q4 | 10,994,953 | $37,808,803 | -$51,251,129 | $3.44 | 88 |
| 2024 Q3 | 9,108,413 | $405,845,227 | +$55,628,540 | $44.62 | 71 |
| 2024 Q2 | 8,065,328 | $144,178,979 | +$11,388,677 | $17.95 | 54 |
| 2024 Q1 | 7,430,290 | $125,894,701 | +$125,894,701 | $17.04 | 38 |