Security Snapshot

Q32 Bio Inc. - Common Stock, $0.0001 par value per share (QTTB) Institutional Ownership

CUSIP: 746964105

13F Institutional Holders and Ownership History from Q1 2024 to Q3 2026

13F reference period

Q2 2026

Institutions Reporting

71

Shares (Excl. Options)

22.19MFull value: 22,189,033 · shares · 30 Jun 2026

Price

$12.74

The headline uses the Q2 2026 reference period after its reporting deadline. Available reports may still be incomplete or amended. Newer periods in the history table contain incoming reports and may be incomplete.

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Latest holder snapshot 5 signals
Portfolio coverage rank
0%
Share change
+12,758,684
Value change
+$167,081,559
Number of holders
71
Issuer context Names, identifiers, and filing context for this profile. 3 identity fields
Shares outstanding
29,847,114
SEC-reported price per share
$8.06
Insider filing price
$8.06
13F Shares, Excluding Options vs Price
13F Value, Excluding Options
Total Investors
Filing notes and source

Key facts

  • QTTB - Q32 Bio Inc. - Common Stock, $0.0001 par value per share is tracked under CUSIP 746964105.
  • 71 institutions reported positions in Q2 2026.
  • 12 significant owners is listed from Schedule 13D/13G reporting.

Change

  • Holder count moved from 53 to 71 between Q1 2026 and Q2 2026.
  • SEC-reported value moved from
    $60.62MFull value: $60,617,009 · USD · 31 Mar 2026
    to
    $282.69MFull value: $282,687,080 · USD · 30 Jun 2026
    .

Research use

  • You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
  • 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.

Evidence

Source: SEC Form 13F

Latest holder context comes from 71 institutions filings for Q2 2026.

Open SEC evidence

Security key

746964105

13F reference period

Q2 2026

13F holders

71

13D/G owners

12

CIK / CUSIP context first

13D/G owners

Significant owners

Large-stake holder rows connected to Schedule 13D/G evidence.

Rows
12
Security
QTTB
Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
ORBIMED ADVISORS LLC 14% -21% $49,329,445 4,127,987 0% ORBIMED ADVISORS LLC 16 Jul 2026
BIOTECHNOLOGY VALUE FUND L P 10% $13,021,382 2,367,524 BVF PARTNERS L P/IL 28 May 2026
Boxer Capital Management, LLC 7.9% -42% $19,004,851 -$6,378,587 2,357,922 -25% Boxer Capital Management, LLC 30 Sep 2026
RA CAPITAL MANAGEMENT, L.P. 9.8% $12,828,514 2,332,457 RA Capital Management, L.P. 28 May 2026
BANK OF AMERICA CORP /DE/ 7.4% $18,244,530 2,205,390 BANK OF AMERICA CORP /DE/ 30 Sep 2026
Frazier Life Sciences Public Fund, L.P. 5.9% $19,481,788 1,755,116 Frazier Life Sciences Public Fund, L.P. 02 Oct 2026
Point72 Asset Management, L.P. 5% -12% $25,087,206 +$4,588,747 1,173,396 +22% Point72 Asset Management, L.P. 30 Jun 2026
Opaleye Management Inc. 3.8% -35% $9,027,200 +$1,523,340 1,120,000 +20% Opaleye Management Inc. 30 Sep 2026
Atlas Venture Fund X, L.P. 3.6% $4,753,436 864,261 Atlas Venture Fund X, L.P. 26 May 2026
Carlyle Group Inc. 4.1% $8,321,572 691,735 The Carlyle Group Inc. 30 Jun 2026
PFIZER INC 2.3% $994,442 277,777 Pfizer Inc. (IRS Identification No.: 13-5315170) 31 Dec 2024
BRISTOL MYERS SQUIBB CO 1.6% $312,381 200,244 BRISTOL MYERS SQUIBB CO 31 Dec 2024
As of 30 Jun 2026, 71 institutional investors reported holding
22.19MFull value: 22,189,033 · shares · 30 Jun 2026
shares of Q32 Bio Inc. - Common Stock, $0.0001 par value per share (QTTB). This represents 74% of the company’s total
29.85MFull value: 29,847,114 · shares · Stored outstanding share count
outstanding shares.

13F concentration

Top 25 institutional shareholders

Largest 13F positions for this security by reported shares and value.

Top holder share
72%
Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
ORBIMED ADVISORS LLC 14% 4,127,987 +83% 1% $52,590,554
Boxer Capital Management, LLC 11% 3,149,310 3% $40,122,209
Atlas Venture Life Science Advisors, LLC 9.1% 2,717,106 +30% 3.9% $34,615,930
BVF INC/IL 7.9% 2,350,000 0.77% $29,939,000
RA CAPITAL MANAGEMENT, L.P. 7.8% 2,332,457 0.26% $29,715,502
Point72 Asset Management, L.P. 3.9% 1,173,396 0.02% $14,949,065
Opaleye Management Inc. 3.1% 931,000 -26% 1.1% $11,860,940
Logos Global Management LP 2.7% 800,000 0.44% $10,192,000
SummitTX Capital, L.P. 2.5% 733,774 0.25% $9,348,281
VANGUARD CAPITAL MANAGEMENT LLC 1.7% 518,803 +69% 0% $6,609,550
Ikarian Capital, LLC 1.4% 430,000 0.9% $5,478,200
Woodline Partners LP 0.96% 286,212 0.01% $3,646,341
AMERICAN CENTURY COMPANIES INC 0.91% 272,752 +1353% 0% $3,474,860
Sanofi 0.82% 244,083 0% 0.58% $3,109,617
ACADIAN ASSET MANAGEMENT LLC 0.73% 218,234 +26% 0% $2,779,000
ACORN CAPITAL ADVISORS, LLC 0.72% 216,171 -31% 0.75% $2,754,019
RENAISSANCE TECHNOLOGIES LLC 0.6% 179,600 -13% 0% $2,288,104
JANE STREET GROUP, LLC 0.55% 162,747 +148% 0% $2,073,396
MONIMUS CAPITAL MANAGEMENT, LP 0.44% 132,036 -1.7% 0.43% $1,682,139
BOOTHBAY FUND MANAGEMENT, LLC 0.44% 130,427 0.03% $1,661,640
GEODE CAPITAL MANAGEMENT, LLC 0.41% 122,690 +3.8% 0% $1,563,506
CITADEL ADVISORS LLC 0.4% 120,663 +679% 0% $1,537,247
BlackRock, Inc. 0.4% 118,507 +38% 0% $1,509,780
MARSHALL WACE, LLP 0.22% 67,045 +28% 0% $854,153
VANGUARD FIDUCIARY TRUST CO 0.22% 66,217 +32% 0% $843,605

Quarter history

Institutional holders across reporting periods

Holder count, reported shares/value, and median price by quarter.

Periods
11
Headline period
Q2 2026
Rows shown
1-11 of 11
Period 13F Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2026 Q3 4,636,937 $38,348,527 +$7,031,803 $8.27 22
2026 Q2 22,189,033 $282,687,080 +$167,081,559 $12.74 71
2026 Q1 9,428,888 $60,617,009 +$9,025,150 $6.42 53
2025 Q4 8,043,846 $26,659,216 -$1,063,038 $3.32 51
2025 Q3 8,428,600 $16,632,224 -$986,951 $1.98 52
2025 Q2 8,978,370 $13,355,302 -$657,201 $1.49 59
2025 Q1 9,406,123 $15,511,257 -$5,227,234 $1.65 71
2024 Q4 10,994,953 $37,808,803 -$51,251,129 $3.44 88
2024 Q3 9,108,413 $405,845,227 +$55,628,540 $44.62 71
2024 Q2 8,065,328 $144,178,979 +$11,388,677 $17.95 54
2024 Q1 7,430,290 $125,894,701 +$125,894,701 $17.04 38
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