Security Snapshot

Q32 Bio Inc. - Common Stock, par value $0.0001 per share (QTTB) Institutional Ownership

CUSIP: 746964105

13F Institutional Holders and Ownership History from Q1 2024 to Q2 2026

Latest Period

Q2 2026

Institutions Reporting

71

Shares (Excl. Options)

22,179,035

Price

$12.74

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Latest holder snapshot 5 signals
Portfolio coverage rank
0%
Share change
+12,748,686
Value change
+$166,954,184
Number of holders
71
Issuer context Names, identifiers, and filing context for this profile. 3 identity fields
Shares outstanding
23,704,970
SEC-reported price per share
$15.56
Insider filing price
$15.56
13F Shares, Excluding Options vs Price
13F Value, Excluding Options
Total Investors

Key facts

  • QTTB - Q32 Bio Inc. - Common Stock, par value $0.0001 per share is tracked under CUSIP 746964105.
  • 71 institutions reported positions in Q2 2026.
  • 10 significant owners is listed from Schedule 13D/13G reporting.

Change

  • Holder count moved from 53 to 71 between Q1 2026 and Q2 2026.
  • SEC-reported value moved from $60,617,009 to $282,559,705.

Research use

  • You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
  • 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.

Evidence

Source: SEC Form 13F

Latest holder context comes from 71 institutions filings for Q2 2026.

Open SEC evidence

Security key

746964105

Latest holder period

Q2 2026

13F holders

71

13D/G owners

10

CIK / CUSIP context first

13D/G owners

Significant owners

Large-stake holder rows connected to Schedule 13D/G evidence.

Rows
10
Security
QTTB
Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
ORBIMED ADVISORS LLC 14% -21% $49,329,445 4,127,987 0% ORBIMED ADVISORS LLC 16 Jul 2026
Boxer Capital Management, LLC 13% $37,886,199 3,149,310 Boxer Capital Management, LLC 30 Jun 2026
BIOTECHNOLOGY VALUE FUND L P 10% $13,021,382 2,367,524 BVF PARTNERS L P/IL 28 May 2026
RA CAPITAL MANAGEMENT, L.P. 9.8% $12,828,514 2,332,457 RA Capital Management, L.P. 28 May 2026
Point72 Asset Management, L.P. 5% -12% $25,087,206 +$4,588,747 1,173,396 +22% Point72 Asset Management, L.P. 30 Jun 2026
Opaleye Management Inc. 5.5% -34% $19,904,780 -$6,953,375 931,000 -26% Opaleye Management Inc. 30 Jun 2026
Atlas Venture Fund X, L.P. 3.6% $4,753,436 864,261 Atlas Venture Fund X, L.P. 26 May 2026
Carlyle Group Inc. 4.1% $8,321,572 691,735 The Carlyle Group Inc. 30 Jun 2026
PFIZER INC 2.3% $994,442 277,777 Pfizer Inc. (IRS Identification No.: 13-5315170) 31 Dec 2024
BRISTOL MYERS SQUIBB CO 1.6% $312,381 200,244 BRISTOL MYERS SQUIBB CO 31 Dec 2024

As of 30 Jun 2026, 71 institutional investors reported holding 22,179,035 shares of Q32 Bio Inc. - Common Stock, par value $0.0001 per share (QTTB). This represents 94% of the company’s total 23,704,970 outstanding shares.

13F concentration

Top 25 institutional shareholders

Largest 13F positions for this security by reported shares and value.

Top holder share
91%
Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
ORBIMED ADVISORS LLC 17% 4,127,987 +83% 1% $52,590,554
Boxer Capital Management, LLC 13% 3,149,310 3% $40,122,209
Atlas Venture Life Science Advisors, LLC 11% 2,717,106 +30% 3.9% $34,615,930
BVF INC/IL 9.9% 2,350,000 0.77% $29,939,000
RA CAPITAL MANAGEMENT, L.P. 9.8% 2,332,457 0.26% $29,715,502
Point72 Asset Management, L.P. 4.9% 1,173,396 0.02% $14,949,065
Opaleye Management Inc. 3.9% 931,000 -26% 1.1% $11,860,940
Logos Global Management LP 3.4% 800,000 0.44% $10,192,000
SummitTX Capital, L.P. 3.1% 733,774 0.25% $9,348,281
VANGUARD CAPITAL MANAGEMENT LLC 2.2% 518,803 +69% 0% $6,609,550
Ikarian Capital, LLC 1.8% 430,000 0.9% $5,478,200
Woodline Partners LP 1.2% 286,212 0.01% $3,646,341
AMERICAN CENTURY COMPANIES INC 1.2% 272,752 +1353% 0% $3,474,860
Sanofi 1% 244,083 0% 0.58% $3,109,617
ACADIAN ASSET MANAGEMENT LLC 0.92% 218,234 +26% 0% $2,779,000
ACORN CAPITAL ADVISORS, LLC 0.91% 216,171 -31% 0.75% $2,754,019
RENAISSANCE TECHNOLOGIES LLC 0.76% 179,600 -13% 0% $2,288,104
JANE STREET GROUP, LLC 0.69% 162,747 +148% 0% $2,073,396
MONIMUS CAPITAL MANAGEMENT, LP 0.56% 132,036 -1.7% 0.43% $1,682,139
BOOTHBAY FUND MANAGEMENT, LLC 0.55% 130,427 0.03% $1,661,640
GEODE CAPITAL MANAGEMENT, LLC 0.52% 122,690 +3.8% 0% $1,563,506
CITADEL ADVISORS LLC 0.51% 120,663 +679% 0% $1,537,247
BlackRock, Inc. 0.5% 118,507 +38% 0% $1,509,780
MARSHALL WACE, LLP 0.28% 67,045 +28% 0% $854,153
VANGUARD FIDUCIARY TRUST CO 0.28% 66,217 +32% 0% $843,605

Quarter history

Institutional holders across reporting periods

Holder count, reported shares/value, and median price by quarter.

Periods
10
Latest
Q2 2026
Rows shown
1-10 of 10
Period 13F Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2026 Q2 22,179,035 $282,559,705 +$166,954,184 $12.74 71
2026 Q1 9,428,888 $60,617,009 +$9,025,150 $6.42 53
2025 Q4 8,043,846 $26,659,216 -$1,063,038 $3.32 51
2025 Q3 8,428,600 $16,632,224 -$986,951 $1.98 52
2025 Q2 8,978,370 $13,355,302 -$657,201 $1.49 59
2025 Q1 9,406,123 $15,511,257 -$5,227,234 $1.65 71
2024 Q4 10,994,953 $37,808,803 -$51,251,129 $3.44 88
2024 Q3 9,108,413 $405,845,227 +$55,628,540 $44.62 71
2024 Q2 8,065,328 $144,178,979 +$11,388,677 $17.95 54
2024 Q1 7,430,290 $125,894,701 +$125,894,701 $17.04 38
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