Latest Period
Q1 2026
Security Snapshot
Sionna Therapeutics, Inc. - Common Stock, $0.001 par value per share (SION) Institutional Ownership
CUSIP: 829401108
13F Institutional Holders and Ownership History from Q1 2025 to Q1 2026
Institutions Reporting
121
Shares (Excl. Options)
45,407,309
Price
$40.09
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- Security type / class
- Equity / Common Stock, $0.001 par value per share
- Symbol
- SION on Nasdaq
- All holders as of 31 Mar 2026
- Q1 2026
- Total 13F shares
- 45,407,309
- Total 13F value
- $1,815,366,651
- Portfolio coverage rank
- 0%
- Share change
- +1,312,630
- Value change
- +$51,789,321
- Number of holders
- 121
- Shares outstanding
- 45,002,549
- SEC-reported price per share
- $40.94
- Insider filing price
- $40.94
Latest holder snapshot
5 signals
Issuer context
Names, identifiers, and filing context for this profile.
3 identity fields
13F Shares, Excluding Options vs Price
13F Value, Excluding Options
Total Investors
Key facts
- SION - Sionna Therapeutics, Inc. - Common Stock, $0.001 par value per share is tracked under CUSIP 829401108.
- 121 institutions reported positions in Q1 2026.
- 8 significant owners is listed from Schedule 13D/13G reporting.
Change
- Holder count moved from 101 to 121 between Q4 2025 and Q1 2026.
- SEC-reported value moved from $1,808,143,956 to $1,815,366,651.
Research use
- You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
- 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.
Evidence
Source: SEC Form 13F
Open SEC evidence
Latest holder context comes from 121 institutions filings for Q1 2026.
Security key
829401108
Latest holder period
Q1 2026
13F holders
121
13D/G owners
8
CIK / CUSIP context first
Open Q1 2026 holders
SION full holder history
Sionna Therapeutics, Inc. SEC filings
Sionna Therapeutics, Inc. company facts
Sionna Therapeutics, Inc. insider transactions
Broader feeds
Recent Quarterly Holder Reports
Open recent reporting periods for CUSIP 829401108:
13D/G owners
Significant owners
Large-stake holder rows connected to Schedule 13D/G evidence.
Rows
8
Security
SION
| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 23% | -4.6% | $296,218,114 | -$10,988,206 | 10,071,712 | -3.6% | RA Capital Management, L.P. | 05 Nov 2025 |
| TPG GP A, LLC | 15% | $80,486,942 | 6,684,962 | TPG GP A, LLC | 10 Feb 2025 | |||
| VIKING GLOBAL INVESTORS LP | 7.1% | +5.7% | $133,462,710 | +$10,126,176 | 3,195,181 | +8.2% | VIKING GLOBAL INVESTORS LP | 31 Mar 2026 |
| ORBIMED ADVISORS LLC | 6.6% | -22% | $118,970,633 | -$29,554,504 | 2,967,722 | -20% | ORBIMED ADVISORS LLC | 15 Apr 2026 |
| Enavate Sciences GP, LLC | 5.6% | $29,835,481 | 2,478,030 | Enavate Sciences GP, LLC | 10 Feb 2025 | |||
| Atlas Venture Fund XI, L.P. | 5.4% | -16% | $74,744,824 | -$15,805,403 | 2,382,495 | -17% | Atlas Venture Fund XI, L.P. | 16 Oct 2025 |
| Qatar Investment Authority | 4.5% | -10% | $84,386,177 | -$7,916,125 | 2,020,258 | -8.6% | Qatar Investment Authority | 31 Mar 2026 |
| JPMORGAN CHASE & CO | 4.4% | -12% | $58,251,993 | -$7,075,145 | 1,980,626 | -11% | JPMORGAN CHASE & CO. | 30 Sep 2025 |
As of 31 Mar 2026, 121 institutional investors reported holding 45,407,309 shares of Sionna Therapeutics, Inc. - Common Stock, $0.001 par value per share (SION). This represents 101% of the company’s total 45,002,549 outstanding shares.
13F concentration
Top 25 institutional shareholders
Largest 13F positions for this security by reported shares and value.
Top holder share
93%
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 22% | 9,905,045 | 0% | 4.2% | $397,093,254 |
| TPG GP A, LLC | 14% | 6,494,962 | -3.7% | 7.1% | $260,383,027 |
| ORBIMED ADVISORS LLC | 7.8% | 3,530,702 | -0.87% | 3.2% | $141,545,843 |
| VIKING GLOBAL INVESTORS LP | 7.1% | 3,195,181 | 0% | 0.36% | $128,094,806 |
| Atlas Venture Life Science Advisors, LLC | 6.7% | 2,995,602 | 0% | 15% | $120,093,684 |
| ENAVATE SCIENCES GP, LLC | 5.5% | 2,478,030 | 0% | 28% | $99,344,223 |
| JPMORGAN CHASE & CO | 3.3% | 1,465,014 | +19% | 0% | $53,707,413 |
| JENNISON ASSOCIATES LLC | 3.2% | 1,451,220 | +30% | 0.04% | $58,179,411 |
| BlackRock, Inc. | 2.9% | 1,295,867 | +0.33% | 0% | $51,951,309 |
| CITADEL ADVISORS LLC | 2.6% | 1,166,931 | +7.3% | 0.03% | $46,782,264 |
| VANGUARD CAPITAL MANAGEMENT LLC | 2.3% | 1,029,497 | 0% | 0% | $41,272,535 |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 2.2% | 970,590 | 0% | 0.46% | $38,910,953 |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1.7% | 756,376 | -9% | 0% | $30,324,000 |
| STATE STREET CORP | 1.7% | 756,227 | +9.1% | 0% | $30,317,140 |
| PERCEPTIVE ADVISORS LLC | 1.5% | 658,439 | -44% | 0.52% | $26,396,820 |
| EVENTIDE ASSET MANAGEMENT, LLC | 1.4% | 645,530 | +1% | 0.43% | $25,875,888 |
| Aberdeen Group plc | 1.3% | 564,175 | -33% | 0.04% | $22,617,776 |
| BAKER BROS. ADVISORS LP | 0.89% | 400,000 | 0% | 0.09% | $16,036,000 |
| GEODE CAPITAL MANAGEMENT, LLC | 0.87% | 389,872 | +2.6% | 0% | $15,633,527 |
| Siren, L.L.C. | 0.67% | 300,000 | 0% | 0.33% | $12,027,000 |
| Sio Capital Management, LLC | 0.65% | 294,340 | 1.7% | $11,800,091 | |
| Soleus Capital Management, L.P. | 0.65% | 293,500 | +9.3% | 0.48% | $11,766,415 |
| GOLDMAN SACHS GROUP INC | 0.58% | 263,174 | +626% | 0% | $10,550,646 |
| Ensign Peak Advisors, Inc | 0.57% | 255,636 | +220% | 0.02% | $10,248,447 |
| Candriam S.C.A. | 0.53% | 236,813 | 0.05% | $9,493,833 |
Quarter history
Institutional holders across reporting periods
Holder count, reported shares/value, and median price by quarter.
Periods
5
Latest
Q1 2026
Rows shown
1-5 of 5
| Period | 13F Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2026 Q1 | 45,407,309 | $1,815,366,651 | +$51,789,321 | $40.09 | 121 |
| 2025 Q4 | 43,950,880 | $1,808,143,956 | +$42,254,824 | $41.14 | 101 |
| 2025 Q3 | 42,840,564 | $1,259,943,482 | -$14,718,322 | $29.41 | 78 |
| 2025 Q2 | 43,448,393 | $753,831,077 | +$37,292,994 | $17.35 | 65 |
| 2025 Q1 | 41,491,947 | $434,056,422 | +$434,056,422 | $10.46 | 47 |