ORBIMED ADVISORS LLC - 25 Mar 2024 Form 3 Insider Report for Homology Medicines, Inc. (QTTB)

Footnote F1

These shares are held of record by OrbiMed Private Investments VII, LP ("OPI VII"). OrbiMed Capital VII LLC ("GP VII"), is the general partner of OPI VII. OrbiMed Advisors LLC ("OrbiMed Advisors"), is the managing member of GP VII. By virtue of such relationships, OrbiMed Advisors and GP VII may be deemed to have voting power and investment power over the securities held by OPI VII and, as a result, may be deemed to have beneficial ownership over such securities. OrbiMed Advisors exercises voting and investment power through a management committee comprised of Carl L. Gordon, Sven H. Borho, and W. Carter Neild, each of whom disclaims beneficial ownership of the securities held by OPI VII.

Footnote F2

Each of OrbiMed Advisors and GP VII disclaims beneficial ownership of the securities reported herein for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), except to the extent of its pecuniary interest therein, if any. OrbiMed Advisors and GP VII have designated a representative, Diyong Xu, to serve on the Issuer's board of directors. This report shall not be deemed an admission that any such person or entity, including the Reporting Persons, is a beneficial owner of such securities for the purpose of Section 16 of the Exchange Act, or for any other purpose.