ORBIMED ADVISORS LLC - 07 Apr 2026 Form 4 Insider Report for Adicet Bio, Inc. (ACET)

Source evidence Original filing metadata and source links for verification. 5 source fields
SEC form
4
Accepted by SEC
09 Apr 2026, 17:38:36 UTC
Prior SEC filing
04 Feb 2026
Next SEC filing
16 Apr 2026
Source filing
View source filing
Reporting owner 1 detail
Reporting owner signature
/s/ Carl L. Gordon, Member of OrbiMed Advisors LLC

Key filing fact

ORBIMED ADVISORS LLC filed Form 4 for Adicet Bio, Inc. (ACET) on 09 Apr 2026.

Key facts

  • This page summarizes ORBIMED ADVISORS LLC's Form 4 filing for Adicet Bio, Inc. (ACET).
  • 4 reported transactions and 0 derivative rows are listed below.
  • Accepted by SEC: 09 Apr 2026, 17:38.

Change

  • Previous filing in this sequence was filed on 04 Feb 2026.
  • Current net transaction value: -$674,847.

Research use

  • This tells you what this filing adds before you inspect full transaction and derivative tables.
  • You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (8)

CIK 0001055951 Primary reporting owner

ORBIMED ADVISORS LLC

Relationship
10%+ Owner
Address
601 LEXINGTON AVENUE, 54TH FLOOR, NEW YORK
Signature
/s/ Carl L. Gordon, Member of OrbiMed Advisors LLC
Signature date
09 Apr 2026
CIK 0001615374

OrbiMed Capital GP V LLC

Relationship
10%+ Owner
Address
601 LEXINGTON AVENUE, 54TH FLOOR, NEW YORK
Signature
/s/ Carl L. Gordon, Member of OrbiMed Capital GP V LLC
Signature date
09 Apr 2026
CIK 0001682115

OrbiMed Capital GP VI LLC

Relationship
10%+ Owner
Address
601 LEXINGTON AVENUE, 54TH FLOOR, NEW YORK
Signature
/s/ Carl L. Gordon, Member of OrbiMed Capital GP VI LLC
Signature date
09 Apr 2026
CIK 0001808744

OrbiMed Genesis GP LLC

Relationship
10%+ Owner
Address
601 LEXINGTON AVENUE, 54TH FLOOR, NEW YORK
Signature
/s/ Carl L. Gordon, Member of OrbiMed Genesis GP LLC
Signature date
09 Apr 2026
CIK 0001682093

OrbiMed Advisors Israel II Ltd

Relationship
10%+ Owner
Address
5 HAHOSHLIM STREET, BUILDING B, 1ST FLOOR, HERZLIYA, ISRAEL
Signature
/s/ Carl L. Gordon, Director of OrbiMed Israel GP Ltd.
Signature date
09 Apr 2026
CIK 0001682090

OrbiMed Israel GP II, L.P.

Relationship
10%+ Owner
Address
5 HAHOSHLIM STREET, BUILDING B, 1ST FLOOR, HERZLIYA, ISRAEL
Signature
/s/ Carl L. Gordon, Director of OrbiMed Advisors Israel II Ltd.
Signature date
09 Apr 2026
CIK 0001569590

OrbiMed Israel GP Ltd.

Relationship
10%+ Owner
Address
5 HAHOSHLIM STREET, BUILDING B, 1ST FLOOR, HERZLIYA, ISRAEL
Signature
/s/ Carl L. Gordon, Director of OrbiMed Israel GP II, L.P.
Signature date
09 Apr 2026
CIK 0001569821

OrbiMed Israel BioFund GP Limited Partnership

Relationship
10%+ Owner
Address
5 HAHOSHLIM STREET, BUILDING B, 1ST FLOOR, HERZLIYA, ISRAEL
Signature
/s/ Carl L. Gordon, Director of OrbiMed Israel BioFund GP Limited Partnership
Signature date
09 Apr 2026

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

ACET transaction

Common Stock

Sale

Transaction value
$191,453
Shares
-29,319
Change %
-46%
Price
$6.53
Shares after
34,923
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F1, F6
ACET transaction

Common Stock

Sale

Transaction value
$191,453
Shares
-29,319
Change %
-46%
Price
$6.53
Shares after
34,923
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F1, F6
ACET transaction

Common Stock

Sale

Transaction value
$191,453
Shares
-29,319
Change %
-46%
Price
$6.53
Shares after
34,923
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F1, F6
ACET transaction

Common Stock

Sale

Transaction value
$191,453
Shares
-29,319
Change %
-46%
Price
$6.53
Shares after
34,923
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F1, F6
ACET transaction

Common Stock

Sale

Transaction value
$191,453
Shares
-29,319
Change %
-46%
Price
$6.53
Shares after
34,923
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F1, F6
ACET transaction

Common Stock

Sale

Transaction value
$191,453
Shares
-29,319
Change %
-46%
Price
$6.53
Shares after
34,923
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F1, F6
ACET transaction

Common Stock

Sale

Transaction value
$191,453
Shares
-29,319
Change %
-46%
Price
$6.53
Shares after
34,923
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F1, F6
ACET transaction

Common Stock

Sale

Transaction value
$191,453
Shares
-29,319
Change %
-46%
Price
$6.53
Shares after
34,923
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F1, F6
ACET transaction

Common Stock

Sale

Transaction value
$15,312
Shares
-2,400
Change %
-6.9%
Price
$6.38
Shares after
32,523
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F1, F6
ACET transaction

Common Stock

Sale

Transaction value
$15,312
Shares
-2,400
Change %
-6.9%
Price
$6.38
Shares after
32,523
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F1, F6
ACET transaction

Common Stock

Sale

Transaction value
$15,312
Shares
-2,400
Change %
-6.9%
Price
$6.38
Shares after
32,523
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F1, F6
ACET transaction

Common Stock

Sale

Transaction value
$15,312
Shares
-2,400
Change %
-6.9%
Price
$6.38
Shares after
32,523
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F1, F6
ACET transaction

Common Stock

Sale

Transaction value
$15,312
Shares
-2,400
Change %
-6.9%
Price
$6.38
Shares after
32,523
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F1, F6
ACET transaction

Common Stock

Sale

Transaction value
$15,312
Shares
-2,400
Change %
-6.9%
Price
$6.38
Shares after
32,523
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F1, F6
ACET transaction

Common Stock

Sale

Transaction value
$15,312
Shares
-2,400
Change %
-6.9%
Price
$6.38
Shares after
32,523
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F1, F6
ACET transaction

Common Stock

Sale

Transaction value
$15,312
Shares
-2,400
Change %
-6.9%
Price
$6.38
Shares after
32,523
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F1, F6
ACET transaction

Common Stock

Sale

Transaction value
$204,570
Shares
-32,523
Change %
-100%
Price
$6.29
Shares after
0
Date
08 Apr 2026
Ownership
See footnotes
Footnotes
F1, F6
ACET transaction

Common Stock

Sale

Transaction value
$204,570
Shares
-32,523
Change %
-100%
Price
$6.29
Shares after
0
Date
08 Apr 2026
Ownership
See footnotes
Footnotes
F1, F6
ACET transaction

Common Stock

Sale

Transaction value
$204,570
Shares
-32,523
Change %
-100%
Price
$6.29
Shares after
0
Date
08 Apr 2026
Ownership
See footnotes
Footnotes
F1, F6
ACET transaction

Common Stock

Sale

Transaction value
$204,570
Shares
-32,523
Change %
-100%
Price
$6.29
Shares after
0
Date
08 Apr 2026
Ownership
See footnotes
Footnotes
F1, F6
ACET transaction

Common Stock

Sale

Transaction value
$204,570
Shares
-32,523
Change %
-100%
Price
$6.29
Shares after
0
Date
08 Apr 2026
Ownership
See footnotes
Footnotes
F1, F6
ACET transaction

Common Stock

Sale

Transaction value
$204,570
Shares
-32,523
Change %
-100%
Price
$6.29
Shares after
0
Date
08 Apr 2026
Ownership
See footnotes
Footnotes
F1, F6
ACET transaction

Common Stock

Sale

Transaction value
$204,570
Shares
-32,523
Change %
-100%
Price
$6.29
Shares after
0
Date
08 Apr 2026
Ownership
See footnotes
Footnotes
F1, F6
ACET transaction

Common Stock

Sale

Transaction value
$204,570
Shares
-32,523
Change %
-100%
Price
$6.29
Shares after
0
Date
08 Apr 2026
Ownership
See footnotes
Footnotes
F1, F6
ACET transaction

Common Stock

Sale

Transaction value
$263,512
Shares
-40,416
Change %
-100%
Price
$6.52
Shares after
0
Date
08 Apr 2026
Ownership
See footnotes
Footnotes
F2, F6
ACET transaction

Common Stock

Sale

Transaction value
$263,512
Shares
-40,416
Change %
-100%
Price
$6.52
Shares after
0
Date
08 Apr 2026
Ownership
See footnotes
Footnotes
F2, F6
ACET transaction

Common Stock

Sale

Transaction value
$263,512
Shares
-40,416
Change %
-100%
Price
$6.52
Shares after
0
Date
08 Apr 2026
Ownership
See footnotes
Footnotes
F2, F6
ACET transaction

Common Stock

Sale

Transaction value
$263,512
Shares
-40,416
Change %
-100%
Price
$6.52
Shares after
0
Date
08 Apr 2026
Ownership
See footnotes
Footnotes
F2, F6
ACET transaction

Common Stock

Sale

Transaction value
$263,512
Shares
-40,416
Change %
-100%
Price
$6.52
Shares after
0
Date
08 Apr 2026
Ownership
See footnotes
Footnotes
F2, F6
ACET transaction

Common Stock

Sale

Transaction value
$263,512
Shares
-40,416
Change %
-100%
Price
$6.52
Shares after
0
Date
08 Apr 2026
Ownership
See footnotes
Footnotes
F2, F6
ACET transaction

Common Stock

Sale

Transaction value
$263,512
Shares
-40,416
Change %
-100%
Price
$6.52
Shares after
0
Date
08 Apr 2026
Ownership
See footnotes
Footnotes
F2, F6
ACET transaction

Common Stock

Sale

Transaction value
$263,512
Shares
-40,416
Change %
-100%
Price
$6.52
Shares after
0
Date
08 Apr 2026
Ownership
See footnotes
Footnotes
F2, F6
ACET holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
78,499
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F3, F6
ACET holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
78,499
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F3, F6
ACET holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
78,499
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F3, F6
ACET holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
78,499
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F3, F6
ACET holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
78,499
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F3, F6
ACET holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
78,499
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F3, F6
ACET holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
78,499
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F3, F6
ACET holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
78,499
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F3, F6
ACET holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
564,147
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F4, F6
ACET holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
564,147
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F4, F6
ACET holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
564,147
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F4, F6
ACET holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
564,147
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F4, F6
ACET holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
564,147
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F4, F6
ACET holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
564,147
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F4, F6
ACET holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
564,147
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F4, F6
ACET holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
564,147
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F4, F6
ACET holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
280,640
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F5, F6
ACET holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
280,640
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F5, F6
ACET holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
280,640
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F5, F6
ACET holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
280,640
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F5, F6
ACET holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
280,640
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F5, F6
ACET holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
280,640
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F5, F6
ACET holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
280,640
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F5, F6
ACET holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
280,640
Date
07 Apr 2026
Ownership
See footnotes
Footnotes
F5, F6
* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Section 16 status

ORBIMED ADVISORS LLC is no longer subject to Section 16 filing requirements. Form 4 or Form 5 obligations may still apply in specific circumstances.

Explanation of responses 6 footnotes

Footnote F1

These securities are held of record by OrbiMed Israel Partners Limited Partnership ("OIP"). OrbiMed Israel BioFund GP Limited Partnership ("OrbiMed BioFund") is the general partner of OIP, and OrbiMed Israel GP Ltd. ("OrbiMed Israel GP") is the general partner of OrbiMed BioFund. By virtue of such relationships, OrbiMed BioFund and OrbiMed Israel GP may be deemed to have voting and investment power over the shares of common stock held by OIP and, as a result, may be deemed to have beneficial ownership over such shares of common stock. OrbiMed Israel GP exercises this investment and voting power through an investment committee comprised of Carl L. Gordon and Erez Chimovits, each of whom disclaims beneficial ownership over the shares of common stock held by OIP.

Footnote F2

These securities are held of record by OrbiMed Israel Partners II, L.P. ("OIP II"). OrbiMed Israel GP II, L.P. ("OrbiMed Israel GP II") is the general partner of OIP II, and OrbiMed Advisors Israel II Limited ("OrbiMed Israel II") is the general partner of OrbiMed Israel GP II. By virtue of such relationships, OrbiMed Israel GP II and OrbiMed Israel II may be deemed to have voting and investment power over the shares of common stock held by OIP II and, as a result, may be deemed to have beneficial ownership over such shares of common stock. OrbiMed Israel II exercises this investment and voting power through an investment committee comprised of Carl L. Gordon, David Bonita, and Erez Chimovits, each of whom disclaims beneficial ownership over the shares of common stock held by OIP II.

Footnote F3

These securities are held of record by OrbiMed Genesis Master Fund, L.P. ("Genesis"). OrbiMed Genesis GP LLC ("Genesis GP") is the general partner of Genesis, and OrbiMed Advisors LLC ("OrbiMed Advisors"), a registered investment adviser under the Investment Advisors Act of 1940, as amended, is the managing member of Genesis. By virtue of such relationships, Genesis GP and OrbiMed Advisors may be deemed to have voting and investment power over the shares of common stock held by Genesis and, as a result, may be deemed to have beneficial ownership over such shares of common stock. OrbiMed Advisors exercises this investment and voting power through a management committee comprised of Carl L. Gordon, Sven H. Borho, and W. Carter Neild, each of whom disclaims beneficial ownership over the shares of common stock held by Genesis.

Footnote F4

These securities are held of record by OrbiMed Private Investments V, LP ("OPI V"). OrbiMed Capital GP V LLC ("GP V") is the general partner of OPI V, and OrbiMed Advisors is the managing member of GP V. By virtue of such relationships, GP V and OrbiMed Advisors may be deemed to have voting and investment power over the shares of common stock held by OPI V and, as a result, may be deemed to have beneficial ownership over such shares of common stock. OrbiMed Advisors exercises this investment and voting power through a management committee comprised of Carl L. Gordon, Sven H. Borho, and W. Carter Neild, each of whom disclaims beneficial ownership over the shares of common stock held by OPI V.

Footnote F5

These securities are held of record by OrbiMed Private Investments VI, LP ("OPI VI"). OrbiMed Capital GP VI LLC ("GP VI") is the general partner of OPI VI, and OrbiMed Advisors is the managing member of GP VI. By virtue of such relationships, GP VI and OrbiMed Advisors may be deemed to have voting and investment power over the shares of common stock held by OPI VI and, as a result, may be deemed to have beneficial ownership over such shares of common stock. OrbiMed Advisors exercises this investment and voting power through a management committee comprised of Carl L. Gordon, Sven H. Borho, and W. Carter Neild, each of whom disclaims beneficial ownership over the shares of common stock held by OPI VI.

Footnote F6

Each of OrbiMed Advisors, OrbiMed BioFund, OrbiMed Israel GP, OrbiMed Israel GP II, OrbiMed Israel II, Genesis GP, GP V, and GP VI disclaims beneficial ownership of the securities reported herein for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), except to the extent of his or its pecuniary interest therein, if any. This report shall not be deemed an admission that any such person or entity is a beneficial owner of such securities for the purpose of Section 16 of the Exchange Act, or for any other purpose.

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