ORBIMED ADVISORS LLC - 10 Sep 2025 Form 4 Insider Report for PMV Pharmaceuticals, Inc. (PMVP)

Role: 10%+ Owner
Signature: /s/ Carl L. Gordon, Member of OrbiMed Advisors
Issuer symbol: PMVP
Transactions as of: 10 Sep 2025
Transactions value $: -$900,000
Form type: 4
Filing time: 12 Sep 2025, 17:09:08 UTC
Previous filing: 02 Sep 2025
Next filing: 10 Oct 2025
SEC: View on sec.gov

Reporting Owners (2)

Name	Relationship	Address	Signature	Signature date	CIK
ORBIMED ADVISORS LLC	10%+ Owner	601 LEXINGTON AVENUE, 54TH FLOOR, NEW YORK	/s/ Carl L. Gordon, Member of OrbiMed Advisors	12 Sep 2025	0001055951
OrbiMed Capital GP V LLC	10%+ Owner	601 LEXINGTON AVENUE, 54TH FLOOR, NEW YORK	/s/ Carl L. Gordon, Member of the Managing Member of OrbiMed Capital GP V LLC	12 Sep 2025	0001615374

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	PMVP	Common Stock	Sale	-$900K	-500K	-7.72%	$1.80	5.98M	10 Sep 2025	See Footnotes	F1, F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	These securities are held of record by OrbiMed Private Investments V, LP ("OPI V"). OrbiMed Capital GP V LLC ("GP V") is the general partner of OPI V, and OrbiMed Advisors LLC ("OrbiMed Advisors"), a registered investment advisor under the Investment Advisors Act of 1940, as amended, is the managing member of GP V. By virtue of such relationships, GP V and OrbiMed Advisors may be deemed to have voting and investment power with respect to the securities held by OPI V. OrbiMed Advisors exercises this investment and voting power through a management committee comprised of Carl L. Gordon, Sven H. Borho, and W. Carter Neild, each of whom disclaims beneficial ownership of the shares held by OPI V.
F2	This report on Form 4 is jointly filed by OrbiMed Advisors and GP V. Each of the Reporting Persons disclaims beneficial ownership of the securities reported herein for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1943, as amended (the "Exchange Act"), except to the extent of its pecuniary interest therein, if any. This report shall not be deemed an admission that any such entity is a beneficial owner of such securities for purpose of Section 16 of the Exchange Act, or for any other purpose.

Content

These securities are held of record by OrbiMed Private Investments V, LP ("OPI V"). OrbiMed Capital GP V LLC ("GP V") is the general partner of OPI V, and OrbiMed Advisors LLC ("OrbiMed Advisors"), a registered investment advisor under the Investment Advisors Act of 1940, as amended, is the managing member of GP V. By virtue of such relationships, GP V and OrbiMed Advisors may be deemed to have voting and investment power with respect to the securities held by OPI V. OrbiMed Advisors exercises this investment and voting power through a management committee comprised of Carl L. Gordon, Sven H. Borho, and W. Carter Neild, each of whom disclaims beneficial ownership of the shares held by OPI V.

This report on Form 4 is jointly filed by OrbiMed Advisors and GP V. Each of the Reporting Persons disclaims beneficial ownership of the securities reported herein for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1943, as amended (the "Exchange Act"), except to the extent of its pecuniary interest therein, if any. This report shall not be deemed an admission that any such entity is a beneficial owner of such securities for purpose of Section 16 of the Exchange Act, or for any other purpose.