| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | VRNA | Ordinary Shares | Sale | -$1.78M | -80K | -1.88% | $22.26 | 4.18M | May 11, 2023 | See footnotes | F1, F2, F3 |
| transaction | VRNA | Ordinary Shares | Sale | -$935K | -43.2K | -1.03% | $21.64 | 4.14M | May 12, 2023 | See footnotes | F1, F2, F3 |
| transaction | VRNA | Ordinary Shares | Sale | -$316K | -14.4K | -0.35% | $21.96 | 4.12M | May 15, 2023 | See footnotes | F1, F2, F3 |
| transaction | VRNA | Ordinary Shares | Sale | -$6.91M | -345K | -8.38% | $20.00 | 3.78M | May 15, 2023 | See footnotes | F1, F2, F3 |
| Id | Content |
|---|---|
| F1 | Consists of American Depository Shares ("ADSs") held of record by OrbiMed Private Investments VI, LP ("OPI VI"). Each ADS represents eight Ordinary Shares of the Issuer. |
| F2 | These securities are held of record by OPI VI. OrbiMed Capital GP VI LLC ("OrbiMed GP") is the general partner of OPI VI, and OrbiMed Advisors LLC ("OrbiMed Advisors") is the managing member of OrbiMed GP. By virtue of such relationships, OrbiMed GP and OrbiMed Advisors may be deemed to have voting power and investment power over the securities held by OPI VI and, as a result, may be deemed to have beneficial ownership over such securities. OrbiMed Advisors exercises voting and investment power through a management committee comprised of Carl L. Gordon, Sven H. Borho, and W. Carter Neild, each of whom disclaims beneficial ownership of the shares held by OPI VI. |
| F3 | This report on Form 4 is jointly filed by OrbiMed Advisors and OrbiMed GP. Each of the Reporting Persons disclaims beneficial ownership of the securities reported herein for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), except to the extent of its pecuniary interest therein, if any. The Reporting Persons have designated a representative, Rishi Gupta, an employee of OrbiMed Advisors, to serve on the Issuer's board of directors. This report shall not be deemed an admission that any such entity or person is a beneficial owner of such securities for purposes of Section 16 of the Exchange Act, or for any other purpose. |