Insider Trading & Ownership of ORBIMED ADVISORS LLC

Location
New York, NY
Summary
The estimated value of insider holdings of ORBIMED ADVISORS LLC is at least $924,362,457 dollars as of 29 Dec 2025. ORBIMED ADVISORS LLC is the 10%+ Owner of SpringWorks Therapeutics, Inc. and owns shares of SpringWorks Therapeutics, Inc. (SWTX) stock worth about $232.56M. ORBIMED ADVISORS LLC is the Director, 10%+ Owner of Enliven Therapeutics, Inc. and owns shares of Enliven Therapeutics, Inc. (ELVN) stock worth about $169.67M. ORBIMED ADVISORS LLC is the Director of Sionna Therapeutics, Inc. and owns shares of Sionna Therapeutics, Inc. (SION) stock worth about $158.67M. ORBIMED ADVISORS LLC is the Director of Verona Pharma plc and owns shares of Verona Pharma plc (VRNA) stock worth about $75.56M. ORBIMED ADVISORS LLC is the Director, 10%+ Owner of Third Harmonic Bio, Inc. and owns shares of Third Harmonic Bio, Inc. (THRD) stock worth about $59.52M. ORBIMED ADVISORS LLC is the 10%+ Owner of NeuroPace Inc and owns shares of NeuroPace Inc (NPCE) stock worth about $51.62M. ORBIMED ADVISORS LLC is the Director, 10%+ Owner of Prelude Therapeutics Inc and owns shares of Prelude Therapeutics Inc (PRLD) stock worth about $38.15M. ORBIMED ADVISORS LLC is the Director, 10%+ Owner of Corvus Pharmaceuticals, Inc. and owns shares of Corvus Pharmaceuticals, Inc. (CRVS) stock worth about $29.8M. ORBIMED ADVISORS LLC is the 10%+ Owner of 89bio, Inc. and owns shares of 89bio, Inc. (ETNB) stock worth about $21.09M. ORBIMED ADVISORS LLC is the 10%+ Owner of TELA Bio, Inc. and owns shares of TELA Bio, Inc. (TELA) stock worth about $10.93M. ORBIMED ADVISORS LLC is the Director of Venetian-1 Acquisition Corp. and owns shares of Lomond Therapeutics Holdings, Inc. stock worth about $10.71M. ORBIMED ADVISORS LLC is the Director of Disc Medicine, Inc. and owns shares of Disc Medicine, Inc. (IRON) stock worth about $10.09M. ORBIMED ADVISORS LLC is the Director, 10%+ Owner of Edgewise Therapeutics, Inc. and owns shares of Edgewise Therapeutics, Inc. (EWTX) stock worth about $8.93M. ORBIMED ADVISORS LLC is the Director, 10%+ Owner of MBX Biosciences, Inc. and owns shares of MBX Biosciences, Inc. (MBX) stock worth about $8.11M. ORBIMED ADVISORS LLC is the 10%+ Owner of PMV Pharmaceuticals, Inc. and owns shares of PMV Pharmaceuticals, Inc. (PMVP) stock worth about $7.56M. ORBIMED ADVISORS LLC is the Director, 10%+ Owner of Terns Pharmaceuticals, Inc. and owns shares of Terns Pharmaceuticals, Inc. (TERN) stock worth about $7.56M. ORBIMED ADVISORS LLC is the Director, 10%+ Owner of ArriVent Biopharma, Inc. and owns shares of ArriVent BioPharma, Inc. (AVBP) stock worth about $5.52M. ORBIMED ADVISORS LLC is the 10%+ Owner of Adicet Bio, Inc. and owns shares of Adicet Bio, Inc. (ACET) stock worth about $4.49M. ORBIMED ADVISORS LLC is the Director, 10%+ Owner of Acutus Medical, Inc. and owns shares of Acutus Medical, Inc. (AFIB) stock worth about $2.62M. ORBIMED ADVISORS LLC is the 10%+ Owner of Passage BIO, Inc. and owns shares of Passage BIO, Inc. (PASG) stock worth about $2M. ORBIMED ADVISORS LLC is the 10%+ Owner of Arcutis Biotherapeutics, Inc. and owns shares of Arcutis Biotherapeutics, Inc. (ARQT) stock worth about $1.47M. ORBIMED ADVISORS LLC is the Director of Janux Therapeutics, Inc. and owns shares of Janux Therapeutics, Inc. (JANX) stock worth about $1.36M. ORBIMED ADVISORS LLC is the Director, 10%+ Owner of Homology Medicines, Inc. and owns shares of Q32 Bio Inc. (QTTB) stock worth about $1.29M. ORBIMED ADVISORS LLC is the 10%+ Owner of Galecto, Inc. and owns shares of Galecto, Inc. (GLTO) stock worth about $1.13M. ORBIMED ADVISORS LLC is the 10%+ Owner of scPharmaceuticals Inc. and owns shares of scPharmaceuticals Inc. (SCPH) stock worth about $1.01M. ORBIMED ADVISORS LLC is the Director of Shattuck Labs, Inc. and owns shares of Shattuck Labs, Inc. (STTK) stock worth about $912K. ORBIMED ADVISORS LLC is the Director of Keros Therapeutics, Inc. and owns shares of Keros Therapeutics, Inc. (KROS) stock worth about $799.8K. ORBIMED ADVISORS LLC is the Director of ImageneBio, Inc. and owns shares of Ikena Oncology, Inc. (IKNA) stock worth about $716.8K. ORBIMED ADVISORS LLC is the 10%+ Owner of Traws Pharma, Inc. and owns shares of Traws Pharma, Inc. (TRAW) stock worth about $282.9K. ORBIMED ADVISORS LLC is the Director of Repare Therapeutics Inc. and owns shares of Repare Therapeutics Inc. (RPTX) stock worth about $233.3K.
Signature
/s/ Carl L. Gordon, Member of OrbiMed Advisors LLC
All Insider Reports
All Insider Reports

Notify me when ORBIMED ADVISORS LLC files a new Insider Trading report.

⭐ Subscribe ⭐

Ownership of ORBIMED ADVISORS LLC

Symbol Company Relationship Holdings Value Past Year Net Change Change % Report Period
SWTX SpringWorks Therapeutics, Inc. 10%+ Owner $232,561,438 12 Sep 2022
ELVN, IMRA Enliven Therapeutics, Inc. Director, 10%+ Owner $169,666,547 16 May 2024
SION Sionna Therapeutics, Inc. Director $158,671,730 -$6,383,642 -3.9% 24 Dec 2025
VRNA Verona Pharma plc Director $75,555,560 11 May 2023
THRD Third Harmonic Bio, Inc. Director, 10%+ Owner $59,522,120 19 Sep 2022
NPCE NeuroPace Inc 10%+ Owner $51,616,892 -$2,665,333 -4.9% 14 May 2025
PRLD Prelude Therapeutics Inc Director, 10%+ Owner $38,151,480 22 May 2023
CRVS Corvus Pharmaceuticals, Inc. Director, 10%+ Owner $29,796,393 -$4,891,894 -14% 27 Jun 2025
ETNB 89bio, Inc. 10%+ Owner $21,093,397 25 Jan 2022
TELA TELA Bio, Inc. 10%+ Owner $10,928,879 28 Jun 2024
NONE Lomond Therapeutics Holdings, Inc. Director $10,709,024 01 Nov 2024
IRON Disc Medicine, Inc. Director $10,093,734 -$20,108,066 -67% 24 Mar 2025
EWTX Edgewise Therapeutics, Inc. Director, 10%+ Owner $8,933,533 +$10,000,000 03 Apr 2025
MBX MBX Biosciences, Inc. Director, 10%+ Owner $8,107,095 +$2,020,756 +33% 14 Feb 2025
PMVP PMV Pharmaceuticals, Inc. 10%+ Owner $7,562,442 -$2,420,000 -24% 23 Oct 2025
TERN Terns Pharmaceuticals, Inc. Director, 10%+ Owner $7,556,350 15 Jul 2024
AVBP ArriVent BioPharma, Inc. Director, 10%+ Owner $5,524,874 30 Jan 2024
ACET Adicet Bio, Inc. 10%+ Owner $4,490,254 +$5,000,000 08 Oct 2025
AFIB Acutus Medical, Inc. Director, 10%+ Owner $2,616,683 19 Jul 2021
PASG Passage BIO, Inc. 10%+ Owner $2,001,893 -$384,599 -16% 24 Jun 2025
ARQT Arcutis Biotherapeutics, Inc. 10%+ Owner $1,469,935 24 Jun 2022
JANX Janux Therapeutics, Inc. Director $1,356,545 29 Dec 2021
QTTB Q32 Bio Inc. Director, 10%+ Owner $1,286,681 25 Mar 2024
GLTO Galecto, Inc. 10%+ Owner $1,132,781 15 Aug 2023
SCPH scPharmaceuticals Inc. 10%+ Owner $1,011,432 13 Aug 2024
STTK Shattuck Labs, Inc. Director $911,970 +$5,471,826 25 Aug 2025
KROS Keros Therapeutics, Inc. Director $799,761 21 Nov 2025
IKNA Ikena Oncology, Inc. Director $716,833 25 Jul 2025
TRAW Traws Pharma, Inc. 10%+ Owner $282,940 29 Dec 2024
RPTX Repare Therapeutics Inc. Director $233,261 03 Sep 2021
ALPN ALPINE IMMUNE SCIENCES, INC. Director $0 18 May 2024
SPRY ARS Pharmaceuticals, Inc. Director $0 26 Aug 2024
CMPX Compass Therapeutics, Inc. Director, 10%+ Owner $0 -$5,678,571 -100% 09 Apr 2025
KNTE Kinnate Biopharma Inc. Director, 10%+ Owner $0 03 Apr 2024
THRX Theseus Pharmaceuticals, Inc. Director, 10%+ Owner $0 14 Feb 2024
TSBX Turnstone Biologics Corp. Director $0 08 Aug 2025
XTNT Xtant Medical Holdings, Inc. 10%+ Owner $0 -$30,708,129 -100% 10 Apr 2025
SRRA Sierra Oncology, Inc. Director, 10%+ Owner 01 Jul 2022
TCDA Tricida, Inc. Director, 10%+ Owner 22 Nov 2022
UPB Upstream Bio, Inc. Director, 10%+ Owner 15 Oct 2024

Insider Transactions Reported by ORBIMED ADVISORS LLC:

Sym Company Class Transaction % Value $ * Price $ Shares Shares After Date Ownership
* An asterisk sign (*) next to the price indicates that the price is likely invalid.