Opaleye Management Inc.

Holdings History for CODEXIS, INC. - Common Stock (CDXS)

Symbol: CDXS on Nasdaq
Investment type: Equity / Common Stock
Latest Disclosed Shares Owned: 6,789,738 shares
Security Ownership %: 7.5%

Shares, Excluding Options vs Price

Value, Excluding Options

Opaleye Management Inc. ownership in CODEXIS, INC. Common Stock (CDXS)

23 Jan 2026 - Opaleye Management Inc. has filed an SCHEDULE 13G/A form with the Securities and Exchange Commission (SEC) disclosing ownership of 6,789,738 shares of CODEXIS, INC. Common Stock (CDXS). This represents 7.5% ownership of the company. In their previous filing dated 05 Dec 2025, Opaleye Management Inc. had reported owning 8,987,989 shares, indicating a decrease of +24%. .

Reporting Name	Ownership %	Change	Value $	Shares owned	Change	Activity %	Price	Form	Report date	Filing time
Opaleye Management Inc.	7.5%	-24%	$11,067,273	6,789,738	-2,198,251	-24%	$1.63	13G/A	31 Dec 2025	23 Jan 2026, 16:05
Opaleye Management Inc.	10%		$17,346,819	8,987,989			$1.93	13G/A	03 Dec 2025	05 Dec 2025, 16:05

Holdings date	Weight	Change	Value $	Shares	Change	Activity %	Price	All Holders
31 Dec 2025	1.5%	-1.3%	$11,067,273	6,789,738	-6,005,262	-47%	$1.63	Q4 2025
30 Sep 2025	4.4%	+0.07%	$31,219,800	12,795,000	+195,000	+1.5%	$2.44	Q3 2025
30 Jun 2025	6.2%	+1.5%	$30,744,000	12,600,000	+3,100,000	+33%	$2.44	Q2 2025
31 Mar 2025	5.7%	+0.4%	$25,555,000	9,500,000	+660,000		$2.69	Q1 2025
31 Dec 2024	7.4%	+0.06%	$42,166,800	8,840,000	+70,000	+0.8%	$4.77	Q4 2024
30 Sep 2024	4.5%	+2.7%	$27,011,600	8,770,000	+5,315,000	+154%	$3.08	Q3 2024
30 Jun 2024	2.4%	+0.23%	$10,710,500	3,455,000	+335,000	+11%	$3.10	Q2 2024
31 Mar 2024	2.4%	+0.06%	$10,888,800	3,120,000	+74,475	+2.4%	$3.49	Q1 2024
31 Dec 2023	2.5%	+1.6%	$9,288,851	3,045,525	+1,926,625	+172%	$3.05	Q4 2023
30 Sep 2023	0.69%	+0.28%	$2,114,721	1,118,900	+443,900	+66%	$1.89	Q3 2023
30 Jun 2023	0.46%	-0.05%	$1,890,000	675,000	-75,000	-10%	$2.80	Q2 2023
31 Mar 2023	0.93%	-0.26%	$3,105,000	750,000	-207,500	-22%	$4.14	Q1 2023
31 Dec 2022	1.6%	-0.32%	$4,461,950	957,500	-197,500	-17%	$4.66	Q4 2022
30 Sep 2022	2.9%	-0.34%	$6,999,000	1,155,000	-133,450	-10%	$6.06	Q3 2022
30 Jun 2022	6.1%	-0.27%	$13,477,000	1,288,450	-56,550	-4.2%	$10.46	Q2 2022
31 Mar 2022	8.6%	0%	$27,734,000	1,345,000	0		$20.62	Q1 2022
31 Dec 2021	8.9%	0%	$42,058,000	1,345,000	0		$31.27	Q4 2021
30 Sep 2021	5.8%	0%	$31,285,000	1,345,000	0		$23.26	Q3 2021
30 Jun 2021	5.3%	-0.22%	$30,478,000	1,345,000	-55,000	-3.9%	$22.66	Q2 2021
31 Mar 2021	4.8%	0%	$32,046,000	1,400,000	0		$22.89	Q1 2021
31 Dec 2020	4.1%	0%	$30,562,000	1,400,000	0		$21.83	Q4 2020
30 Sep 2020	3.4%	0%	$16,436,000	1,400,000	0		$11.74	Q3 2020
30 Jun 2020	3.3%	0%	$16,089,000	1,400,000	0		$11.49	Q2 2020
31 Mar 2020	4.1%	0%	$15,624,000	1,400,000	0		$11.16	Q1 2020
31 Dec 2019	4.4%	+0.16%	$22,286,000	1,400,000	+50,000	+3.7%	$15.92	Q4 2019
30 Sep 2019	6.7%	0%	$18,515,000	1,350,000	0		$13.71	Q3 2019
30 Jun 2019	7.6%	-0.7%	$24,881,000	1,350,000	-125,000	-8.5%	$18.43	Q2 2019
31 Mar 2019	8.4%	-1.6%	$30,282,000	1,475,000	-275,000	-16%	$20.53	Q1 2019
31 Dec 2018	11%	0%	$29,225,000	1,750,000	0		$16.70	Q4 2018
30 Sep 2018	7.6%	0%	$30,012,000	1,750,000	0		$17.15	Q3 2018
30 Jun 2018	6.6%	+0.19%	$25,200,000	1,750,000	+49,400	+2.9%	$14.40	Q2 2018
31 Mar 2018	5.3%	0%	$18,706,000	1,700,600	0		$11.00	Q1 2018
31 Dec 2017	4.5%	0%	$14,200,000	1,700,600	0		$8.35	Q4 2017
30 Sep 2017	4%	+0.54%	$11,309,000	1,700,600	+230,600	+16%	$6.65	Q3 2017
30 Jun 2017	3.3%	+0.68%	$8,011,000	1,470,000	+300,000	+26%	$5.45	Q2 2017
31 Mar 2017	2.8%	0%	$5,616,000	1,170,000	0		$4.80	Q1 2017
31 Dec 2016	3.2%	0%	$5,382,000	1,170,000	0		$4.60	Q4 2016
30 Sep 2016	2.7%	-0.02%	$5,195,000	1,170,000	-8,500	-0.72%	$4.44	Q3 2016
30 Jun 2016	3.2%	0%	$4,749,000	1,178,500	0		$4.03	Q2 2016
31 Mar 2016	2.5%	-0.89%	$3,665,000	1,178,500	-421,500	-26%	$3.11	Q1 2016
31 Dec 2015	2.8%	-0.04%	$6,768,000	1,600,000	-20,000	-1.2%	$4.23	Q4 2015
30 Sep 2015	2.7%	-0.17%	$5,492,000	1,620,000	-104,000	-6%	$3.39	Q3 2015
30 Jun 2015	2.8%	0%	$6,706,000	1,724,000	0		$3.89	Q2 2015
31 Mar 2015	3.6%	0%	$7,861,000	1,724,000	0		$4.56	Q1 2015
31 Dec 2014	2.2%	+0.04%	$4,344,000	1,724,000	+34,000	+2%	$2.52	Q4 2014
30 Sep 2014	3.1%	+1.6%	$3,937,700	1,690,000	+870,000	+106%	$2.33	Q3 2014
30 Jun 2014	1%	+0.15%	$1,197,000	820,000	+121,700	+17%	$1.46	Q2 2014
31 Mar 2014	1.1%	+1.1%	$1,425,000	698,300	+698,300	NEW	$2.04	Q1 2014

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.