Quick Takeaways
- Opaleye Management Inc. has 9 issuer positions tracked on this page.
- Estimated disclosed ownership value: $287,571,486.
- Recent insider filing activity is available below.
Insider Trading & Ownership of Opaleye Management Inc.
- Location
- Boston, MA
- Summary
- The estimated value of insider holdings of Opaleye Management Inc. is at least $287,571,486 dollars as of 30 Apr 2026. Opaleye Management Inc. is the 10%+ Owner of HARROW, INC. and owns shares of HARROW, INC. (HROW) stock worth about $146.05M. Opaleye Management Inc. is the 10%+ Owner of Eton Pharmaceuticals, Inc. and owns shares of Eton Pharmaceuticals, Inc. (ETON) stock worth about $45.18M. Opaleye Management Inc. is the 10%+ Owner of Sol-Gel Technologies Ltd. and owns shares of Sol-Gel Technologies Ltd. (SLGL) stock worth about $36M. Opaleye Management Inc. is the 10%+ Owner of CODEXIS, INC. and owns shares of CODEXIS, INC. (CDXS) stock worth about $16.9M. Opaleye Management Inc. is the 10%+ Owner of SANUWAVE Health, Inc. and owns shares of SANUWAVE Health, Inc. (SNWV) stock worth about $15.42M. Opaleye Management Inc. is the 10%+ Owner of Alpha Cognition Inc. and owns shares of Alpha Cognition Inc. (ACOG) stock worth about $12.91M. Opaleye Management Inc. is the Former 10% Owner. of TELA Bio, Inc. and owns shares of TELA Bio, Inc. (TELA) stock worth about $11.71M. Opaleye Management Inc. is the 10%+ Owner of Protara Therapeutics, Inc. and owns shares of Protara Therapeutics, Inc. (TARA) stock worth about $3.4M.
- Signature
- Opaleye Management Inc., By: /s/ James Silverman, President
- All Insider Reports
- All Insider Reports
Follow Filing Activity
Follow Opaleye Management Inc. and return when a new Insider Trading filing changes the record on this page.
This uses the existing product follow flow to surface future filing-backed changes without guessing what they mean.
What Changed
- Largest disclosed position: HARROW, INC. ($146,049,979).
- Past-year value change for that position: -$10,643,994.
Why This Matters
- This page translates Forms 3/4/5 into a quick ownership context before you inspect each transaction row.
- You can cross-check role, issuer, and filing chronology directly against the SEC source.
Source Evidence
Filed on Form 4
See Original Filing
Insider ownership context is sourced from SEC Forms 3, 4, and 5.
Ownership of Opaleye Management Inc.
| Symbol | Company | Relationship | Holdings Value | Past Year Net Change | Change % | Report Period |
|---|---|---|---|---|---|---|
| HROW | HARROW, INC. | 10%+ Owner | $146,049,979 | -$10,643,994 | -6.8% | 03 Mar 2026 |
| ETON | Eton Pharmaceuticals, Inc. | 10%+ Owner | $45,177,234 | +$125,484 | +0.28% | 10 Jun 2025 |
| SLGL | Sol-Gel Technologies Ltd. | 10%+ Owner | $36,000,000 | +$6,731,517 | +23% | 24 Mar 2026 |
| CDXS | CODEXIS, INC. | 10%+ Owner | $16,900,093 | +$5,425,230 | +47% | 26 Nov 2025 |
| SNWV | SANUWAVE Health, Inc. | 10%+ Owner | $15,421,941 | -$1,573,592 | -9.3% | 28 Apr 2026 |
| ACOG | Alpha Cognition Inc. | 10%+ Owner | $12,912,857 | +$2,130,553 | +20% | 27 Mar 2026 |
| TELA | TELA Bio, Inc. | Former 10% Owner. | $11,710,150 | 20 Apr 2023 | ||
| TARA | Protara Therapeutics, Inc. | 10%+ Owner | $3,399,232 | 11 Sep 2024 | ||
| TCON | Tracon Pharmaceuticals, Inc. | 10%+ Owner | 10 Nov 2023 |
Insider Transactions Reported by Opaleye Management Inc.:
| Sym | Company | Class | Transaction | % | Value $ | * Price $ | Shares | Shares After | Date | Ownership |
|---|
* An asterisk sign (*) next to the price indicates that the price is likely invalid.