| Quarter | Holdings | Value $ | Bought | Sold | Net | Top Holdings | Form Type | Date Filed |
|---|
Quarter | Holdings | Value $ | Bought | Sold | Net | Top Holdings | Form Type | Date Filed |
|---|---|---|---|---|---|---|---|---|
| Q4 2024 | 39 | $571M | +$40.1M | -$63.7M | -$23.6M | HROW, TGTX, CDXS, ETON, OCUL | 13F-HR | 2/14/2025, 04:05 PM |
| Q3 2024 | 44 | $600M | +$72.9M | -$66.9M | +$6.02M | HROW, TGTX, OCUL, ARVN, CDXS | 13F-HR | 11/14/2024, 04:05 PM |
| Q2 2024 | 51 | $438M | +$74.6M | -$59.2M | +$15.3M | HROW, TGTX, OCUL, RYTM, KROS | 13F-HR | 8/14/2024, 04:05 PM |
| Q1 2024 | 52 | $459M | +$77.1M | -$78.3M | -$1.2M | OCUL, HROW, TGTX, KROS, RYTM | Restatement | 5/29/2024, 04:05 PM |
| Q4 2023 | 47 | $373M | +$63.1M | -$56.4M | +$6.73M | HROW, TGTX, SLRN, RYTM, OCUL | 13F-HR | 2/14/2024, 04:05 PM |
| Q3 2023 | 41 | $305M | +$48.5M | -$88.3M | -$39.8M | HROW, SLRN, OCUL, TGTX, RYTM | 13F-HR | 11/14/2023, 08:04 PM |
| Q2 2023 | 47 | $415M | +$135M | -$34.6M | +$100M | SLRN, HROW, OCUL, TELA, CRNX | 13F-HR | 8/14/2023, 05:11 PM |
| Q1 2023 | 41 | $334M | +$42.1M | -$22M | +$20.1M | HROW, OCUL, TELA, RYTM, CRNX | 13F-HR | 5/12/2023, 06:49 PM |
| Q4 2022 | 40 | $288M | +$59.8M | -$44.9M | +$14.9M | HROW, TELA, RYTM, OCUL, CRNX | 13F-HR | 2/10/2023, 04:05 PM |
| Q3 2022 | 42 | $239M | +$30.3M | -$40.7M | -$10.4M | HROW, OCUL, RYTM, TELA, CRNX | 13F-HR | 11/14/2022, 04:20 PM |
| Q2 2022 | 47 | $222M | +$35.6M | -$57.3M | -$21.7M | HROW, OCUL, CDXS, CRNX, CYTK | 13F-HR | 8/15/2022, 04:03 PM |
| Q1 2022 | 45 | $322M | +$33.6M | -$60.4M | -$26.8M | OCUL, CDXS, CMRX, HROW, CRNX | 13F-HR | 5/16/2022, 04:05 PM |
| Q4 2021 | 39 | $471M | +$55.8M | -$74.4M | -$18.7M | CDXS, OCUL, CMRX, CLDX, HROW | 13F-HR | 2/14/2022, 04:05 PM |
| Q3 2021 | 48 | $535M | +$61M | -$46.9M | +$14.1M | OCUL, CLDX, CDXS, CMRX, HROW | 13F-HR | 11/15/2021, 07:17 PM |
| Q2 2021 | 48 | $573M | +$45.3M | -$94.6M | -$49.3M | OCUL, CMRX, CLDX, BBIO, CDXS | 13F-HR | 8/16/2021, 05:13 PM |
| Q1 2021 | 58 | $671M | +$147M | -$168M | -$21.4M | OCUL, CMRX, TARA, BBIO, CDXS | 13F-HR | 5/17/2021, 07:03 PM |
| Q4 2020 | 59 | $748M | +$84M | -$53M | +$30.9M | OCUL, TARA, EIDX, ETON, CDXS | 13F-HR | 2/12/2021, 05:15 PM |
| Q3 2020 | 55 | $489M | +$124M | -$71.9M | +$51.6M | OCUL, TARA, ETON, CRDF, AFIB | 13F-HR | 11/16/2020, 04:30 PM |
| Q2 2020 | 48 | $487M | +$183M | -$150M | +$33.3M | TARA, OCUL, NLTX, CCXI, ETON | 13F-HR | 8/14/2020, 04:47 PM |
| Q1 2020 | 43 | $377M | +$103M | -$178M | -$75.1M | TARA, FTSV, OCUL, NLTX, CDXS | 13F-HR | 5/15/2020, 04:30 PM |
| Q4 2019 | 47 | $510M | +$106M | -$31.7M | +$74.8M | EPZM, CDXS, FTSV, STXS, TPTX | 13F-HR | 2/14/2020, 04:30 PM |
| Q3 2019 | 49 | $277M | +$67.5M | -$60.7M | +$6.82M | CDXS, STXS, EPZM, IMMY, EIDX | 13F-HR | 11/14/2019, 04:30 PM |
| Q2 2019 | 43 | $328M | +$64M | -$112M | -$47.8M | CDXS, IMMY, AXGN, EPZM, QURE | 13F-HR | 8/14/2019, 04:30 PM |
| Q1 2019 | 53 | $361M | +$134M | -$107M | +$26.7M | CDXS, AXGN, EPZM, CERC, AMRN | 13F-HR | 5/15/2019, 04:30 PM |
| Q4 2018 | 47 | $268M | +$47.4M | -$77.6M | -$30.2M | CDXS, AXGN, LOXO, AMRN, BPMC | 13F-HR | 2/14/2019, 05:00 PM |
| Q3 2018 | 47 | $393M | +$45M | -$41.1M | +$3.85M | AXGN, CDXS, LOXO, AMRN, BPMC | 13F-HR | 11/14/2018, 04:30 PM |
| Q2 2018 | 36 | $383M | +$94.3M | -$90.2M | +$4.1M | AXGN, LOXO, CDXS, FGEN, BPMC | 13F-HR | 8/14/2018, 04:31 PM |
| Q1 2018 | 38 | $350M | +$70.3M | -$88.5M | -$18.2M | AXGN, BPMC, LOXO, CDXS, FGEN | 13F-HR | 5/14/2018, 05:00 PM |
| Q4 2017 | 35 | $312M | +$63.7M | -$63.9M | -$234K | AXGN, BPMC, FGEN, LOXO, IMMU | 13F-HR | 2/9/2018, 04:30 PM |
| Q3 2017 | 34 | $282M | +$36.8M | -$48.1M | -$11.3M | BPMC, AXGN, FGEN, IMMU, LOXO | 13F-HR | 11/14/2017, 04:17 PM |
| Q2 2017 | 41 | $239M | +$36.2M | -$30.6M | +$5.52M | BPMC, AXGN, FGEN, LOXO, SBBP | 13F-HR | 8/14/2017, 04:34 PM |
| Q1 2017 | 44 | $201M | +$40.7M | -$34.6M | +$6.15M | BPMC, AXGN, FGEN, NVLNF, CMRX | 13F-HR | 5/15/2017, 06:15 AM |
| Q4 2016 | 40 | $168M | +$44.5M | -$57.4M | -$12.9M | BPMC, AXGN, ARIA, GNMX, FGEN | 13F-HR | 2/21/2017, 04:27 PM |
| Q3 2016 | 44 | $191M | +$33.8M | -$36M | -$2.19M | BPMC, AXGN, ARIA, MDGN, AGIO | 13F-HR | 11/14/2016, 12:30 PM |
| Q2 2016 | 49 | $150M | +$30.6M | -$41.1M | -$10.4M | AXGN, MDGN, ARIA, FGEN, BPMC | Restatement | 8/12/2016, 04:35 PM |
| Q1 2016 | 52 | $147M | +$32.7M | -$58.9M | -$26.2M | AXGN, ARIA, RARE, FGEN, MDGN | Restatement | 5/27/2016, 03:29 PM |
| Q4 2015 | 53 | $239M | +$50M | -$42.5M | +$7.57M | RARE, AXGN, FGEN, GERN, MDGN | 13F-HR | 2/12/2016, 12:57 PM |
| Q3 2015 | 49 | $203M | +$31.5M | -$49.5M | -$18.1M | CMRX, RARE, CEMP, AXGN, MDGN | 13F-HR | 11/13/2015, 10:44 AM |
| Q2 2015 | 46 | $243M | +$41.6M | -$38.2M | +$3.38M | CMRX, CEMP, RTRX, AMAG, ARIA | 13F-HR | 8/14/2015, 10:27 AM |
| Q1 2015 | 37 | $215M | +$50.1M | -$67.3M | -$17.2M | CMRX, CEMP, ARIA, RTRX, CLVSQ | 13F-HR | 5/15/2015, 11:41 AM |
| Q4 2014 | 36 | $198M | +$53.6M | -$21.3M | +$32.3M | CMRX, AGIO, CEMP, RTRX, ARIA | 13F-HR | 2/13/2015, 07:06 AM |
| Q3 2014 | 30 | $128M | +$25.7M | -$14.1M | +$11.6M | CMRX, PCYC, RTRX, ARIA, AGIO | 13F-HR | 11/14/2014, 10:27 AM |
| Q2 2014 | 27 | $116M | +$30.2M | -$35M | -$4.86M | CMRX, RTRX, ARIA, PCYC, GNMK | 13F-HR | 8/14/2014, 10:19 AM |
| Q1 2014 | 30 | $135M | +$63.5M | -$49.6M | +$13.8M | RTRX, ARIA, CMRX, PCYC, NSPR | 13F-HR | 5/15/2014, 10:48 AM |
| Q4 2013 | 23 | $127M | $0 | $0 | GENTY, GERN, PCYC, ARIA, P103PS | 13F-HR | 2/13/2014, 07:29 PM |