Opaleye Management Inc.

13F Filings History

Latest 13F report
Q2 2024 - Aug 14, 2024
Value $
$438M
Signature - Title
James Silverman - President
Location
Boston, MA
Summary
This page shows a list of all the recent 13F filings made by Opaleye Management Inc.. Form 13F is required to be filed within 45 days of the end of a calendar quarter. Opaleye Management Inc. reported 51 stock holdings with total value $438M as of Q2 2024. Top holdings included HROW, TGTX, OCUL, RYTM, and KROS.
Holdings Value
Quarter Holdings Value $ Bought Sold Net Top Holdings Form Type Date Filed
Q2 2024 51 $438M +$74.6M -$59.2M +$15.3M HROW, TGTX, OCUL, RYTM, KROS 13F-HR 8/14/2024, 04:05 PM
Q1 2024 52 $459M +$77.1M -$78.3M -$1.2M OCUL, HROW, TGTX, KROS, RYTM Restatement 5/29/2024, 04:05 PM
Q4 2023 47 $373M +$63.1M -$56.4M +$6.73M HROW, TGTX, SLRN, RYTM, OCUL 13F-HR 2/14/2024, 04:05 PM
Q3 2023 41 $305M +$48.5M -$88.3M -$39.8M HROW, SLRN, OCUL, TGTX, RYTM 13F-HR 11/14/2023, 08:04 PM
Q2 2023 47 $415M +$135M -$34.6M +$100M SLRN, HROW, OCUL, TELA, CRNX 13F-HR 8/14/2023, 05:11 PM
Q1 2023 41 $334M +$42.1M -$22M +$20.1M HROW, OCUL, TELA, RYTM, CRNX 13F-HR 5/12/2023, 06:49 PM
Q4 2022 40 $288M +$59.8M -$44.9M +$14.9M HROW, TELA, RYTM, OCUL, CRNX 13F-HR 2/10/2023, 04:05 PM
Q3 2022 42 $239M +$30.3M -$40.7M -$10.4M HROW, OCUL, RYTM, TELA, CRNX 13F-HR 11/14/2022, 04:20 PM
Q2 2022 47 $222M +$35.6M -$57.3M -$21.7M HROW, OCUL, CDXS, CRNX, CYTK 13F-HR 8/15/2022, 04:03 PM
Q1 2022 45 $322M +$33.6M -$60.4M -$26.8M OCUL, CDXS, CMRX, HROW, CRNX 13F-HR 5/16/2022, 04:05 PM
Q4 2021 39 $471M +$55.8M -$74.4M -$18.7M CDXS, OCUL, CMRX, CLDX, HROW 13F-HR 2/14/2022, 04:05 PM
Q3 2021 48 $535M +$61M -$46.9M +$14.1M OCUL, CLDX, CDXS, CMRX, HROW 13F-HR 11/15/2021, 07:17 PM
Q2 2021 48 $573M +$45.3M -$94.6M -$49.3M OCUL, CMRX, CLDX, BBIO, CDXS 13F-HR 8/16/2021, 05:13 PM
Q1 2021 58 $671M +$147M -$168M -$21.4M OCUL, CMRX, TARA, BBIO, CDXS 13F-HR 5/17/2021, 07:03 PM
Q4 2020 59 $748M +$84M -$53M +$30.9M OCUL, TARA, EIDX, ETON, CDXS 13F-HR 2/12/2021, 05:15 PM
Q3 2020 55 $489M +$124M -$71.9M +$51.6M OCUL, TARA, ETON, CRDF, AFIB 13F-HR 11/16/2020, 04:30 PM
Q2 2020 48 $487M +$183M -$150M +$33.3M TARA, OCUL, NLTX, CCXI, ETON 13F-HR 8/14/2020, 04:47 PM
Q1 2020 43 $377M +$103M -$178M -$75.1M TARA, FTSV, OCUL, NLTX, CDXS 13F-HR 5/15/2020, 04:30 PM
Q4 2019 47 $510M +$106M -$31.7M +$74.8M EPZM, CDXS, FTSV, STXS, TPTX 13F-HR 2/14/2020, 04:30 PM
Q3 2019 49 $277M +$67.5M -$60.7M +$6.82M CDXS, STXS, EPZM, IMMY, EIDX 13F-HR 11/14/2019, 04:30 PM
Q2 2019 43 $328M +$64M -$112M -$47.8M CDXS, IMMY, AXGN, EPZM, QURE 13F-HR 8/14/2019, 04:30 PM
Q1 2019 53 $361M +$134M -$107M +$26.7M CDXS, AXGN, EPZM, CERC, AMRN 13F-HR 5/15/2019, 04:30 PM
Q4 2018 47 $268M +$47.4M -$77.6M -$30.2M CDXS, AXGN, LOXO, AMRN, BPMC 13F-HR 2/14/2019, 05:00 PM
Q3 2018 47 $393M +$45M -$41.1M +$3.85M AXGN, CDXS, LOXO, AMRN, BPMC 13F-HR 11/14/2018, 04:30 PM
Q2 2018 36 $383M +$94.3M -$90.2M +$4.1M AXGN, LOXO, CDXS, FGEN, BPMC 13F-HR 8/14/2018, 04:31 PM
Q1 2018 38 $350M +$70.3M -$88.5M -$18.2M AXGN, BPMC, LOXO, CDXS, FGEN 13F-HR 5/14/2018, 05:00 PM
Q4 2017 35 $312M +$63.7M -$63.9M -$234K AXGN, BPMC, FGEN, LOXO, IMMU 13F-HR 2/9/2018, 04:30 PM
Q3 2017 34 $282M +$36.8M -$48.1M -$11.3M BPMC, AXGN, FGEN, IMMU, LOXO 13F-HR 11/14/2017, 04:17 PM
Q2 2017 41 $239M +$36.2M -$30.6M +$5.52M BPMC, AXGN, FGEN, LOXO, SBBP 13F-HR 8/14/2017, 04:34 PM
Q1 2017 44 $201M +$40.7M -$34.6M +$6.15M BPMC, AXGN, FGEN, NVLNF, CMRX 13F-HR 5/15/2017, 06:15 AM
Q4 2016 40 $168M +$44.5M -$57.4M -$12.9M BPMC, AXGN, ARIA, GNMX, FGEN 13F-HR 2/21/2017, 04:27 PM
Q3 2016 44 $191M +$33.8M -$36M -$2.19M BPMC, AXGN, ARIA, MDGN, AGIO 13F-HR 11/14/2016, 12:30 PM
Q2 2016 49 $150M +$30.6M -$41.1M -$10.4M AXGN, MDGN, ARIA, FGEN, BPMC Restatement 8/12/2016, 04:35 PM
Q1 2016 52 $147M +$32.7M -$58.9M -$26.2M AXGN, ARIA, RARE, FGEN, MDGN Restatement 5/27/2016, 03:29 PM
Q4 2015 53 $239M +$50M -$42.5M +$7.57M RARE, AXGN, FGEN, GERN, MDGN 13F-HR 2/12/2016, 12:57 PM
Q3 2015 49 $203M +$31.5M -$49.5M -$18.1M CMRX, RARE, CEMP, AXGN, MDGN 13F-HR 11/13/2015, 10:44 AM
Q2 2015 46 $243M +$41.6M -$38.2M +$3.38M CMRX, CEMP, RTRX, AMAG, ARIA 13F-HR 8/14/2015, 10:27 AM
Q1 2015 37 $215M +$50.1M -$67.3M -$17.2M CMRX, CEMP, ARIA, RTRX, CLVSQ 13F-HR 5/15/2015, 11:41 AM
Q4 2014 36 $198M +$53.6M -$21.3M +$32.3M CMRX, AGIO, CEMP, RTRX, ARIA 13F-HR 2/13/2015, 07:06 AM
Q3 2014 30 $128M +$25.7M -$14.1M +$11.6M CMRX, PCYC, RTRX, ARIA, AGIO 13F-HR 11/14/2014, 10:27 AM
Q2 2014 27 $116M +$30.2M -$35M -$4.86M CMRX, RTRX, ARIA, PCYC, GNMK 13F-HR 8/14/2014, 10:19 AM
Q1 2014 30 $135M +$63.5M -$49.6M +$13.8M RTRX, ARIA, CMRX, PCYC, NSPR 13F-HR 5/15/2014, 10:48 AM
Q4 2013 23 $127M $0 $0 GENTY, GERN, PCYC, ARIA, P103PS 13F-HR 2/13/2014, 07:29 PM