Insider Transactions Reported by 22 Insiders of Karyopharm Therapeutics Inc.

Symbol
KPTI on Nasdaq
Location
Newton, MA

Insiders trading volume in the past year

Karyopharm Therapeutics Inc. executives and other stock owners filed with the SEC include:

Name Relationship Holdings Value Past Year Net Change Change % Report Date
Richard A. Paulson President and CEO, Director $2,512,618 -$126,990 -4.8% 02 Mar 2026
Sharon Shacham Chief Scientific Officer $1,370,948 29 Mar 2022
Michael Kauffman Director $1,321,748 28 Feb 2022
Sohanya Roshan Cheng EVP & Chief Commercial Officer $1,009,799 -$45,411 -4.3% 02 Mar 2026
Stuart Poulton EVP, Chief Development Officer $887,579 -$54,673 -5.8% 02 Mar 2026
Michael Mano EVP, CLO&Secretary $884,154 -$34,683 -3.8% 02 Mar 2026
Michael Mason EVP, CFO & Treasurer $760,770 04 Sep 2024
Lori Macomber EVP, CFO & Treasurer $536,161 -$10,244 -1.9% 03 Feb 2026
Reshma Rangwala EVP & Chief Medical Officer $533,885 -$52,877 -9% 02 Mar 2026
Kristin Abate Chief Accounting Officer $207,601 -$10,651 -4.9% 02 Mar 2026
Ran Frenkel EVP, Chief Dev. Officer $137,998 28 Feb 2022
Jatin Shah EVP, Chief Medical Officer $106,149 17 Feb 2022
Stephen Mitchener SVP, Chief Business Officer $105,217 28 Feb 2023
DEEPIKA PAKIANATHAN Director $0 28 May 2025
Mansoor Raza Mirza Director 28 May 2025
Mikael Dolsten Director 21 May 2021
Christy J. Oliger Director 28 May 2025
Barry E. Greene Director 28 May 2025
Chen Schor Director 28 May 2025
Zhen Su Director 28 May 2025
GAREN G. BOHLIN Director 28 May 2025
Peter Honig Director 24 May 2023

Recent Insider Transactions by Companies or Individuals for Karyopharm Therapeutics Inc.

Insider Symbol Class Transaction % Value $ * Price $ Shares Shares Owned Date Ownership
Kristin Abate KPTI Common Stock Sale -2.47% $5,260 $9.41 -559 22,063 02 Mar 2026 Direct
Michael Mano KPTI Common Stock Sale -3.62% $33,178 $9.41 -3,526 93,964 02 Mar 2026 Direct
Sohanya Roshan Cheng KPTI Common Stock Sale -4.11% $43,321 $9.41 -4,604 107,317 02 Mar 2026 Direct
Reshma Rangwala KPTI Common Stock Sale -8.2% $47,669 $9.41 -5,066 56,739 02 Mar 2026 Direct
Richard A. Paulson KPTI Common Stock Sale -4.42% $116,311 $9.41 -12,361 267,030 02 Mar 2026 Direct
Stuart Poulton KPTI Common Stock Sale -5.13% $47,998 $9.41 -5,101 94,328 02 Mar 2026 Direct
Stuart Poulton KPTI Common Stock Sale -0.38% $3,262 $8.63 -378 99,429 17 Feb 2026 Direct
Richard A. Paulson KPTI Common Stock Award 40.9% 81,060 279,391 05 Feb 2026 Direct
Lori Macomber KPTI Common Stock Sale -1.87% $10,244 $6.30 -1,626 85,105 03 Feb 2026 Direct
Sohanya Roshan Cheng KPTI Common Stock Award 40.8% 32,415 111,921 31 Jan 2026 Direct
Reshma Rangwala KPTI Common Stock Award 110.3% 32,415 61,805 31 Jan 2026 Direct
Lori Macomber KPTI Common Stock Award 59.7% 32,415 86,731 31 Jan 2026 Direct
Michael Mano KPTI Common Stock Award 49.8% 32,415 97,490 31 Jan 2026 Direct
Stuart Poulton KPTI Common Stock Award 48.1% 32,415 99,807 31 Jan 2026 Direct
Kristin Abate KPTI Common Stock Sale -0.22% $352 $7.03 -50 22,622 28 Jan 2026 Direct
Kristin Abate KPTI Common Stock Award 0.41% 92 22,672 27 Jan 2026 Direct
Kristin Abate KPTI Common Stock Sale -1.16% $1,579 $5.96 -265 22,580 21 Jan 2026 Direct
Kristin Abate KPTI Common Stock Award 127.4% 12,799 22,845 15 Oct 2025 Direct
Stuart Poulton KPTI Common Stock Award 143.2% 39,682 67,392 15 Oct 2025 Direct
Michael Mano KPTI Common Stock Award 203.7% 43,650 65,075 15 Oct 2025 Direct
Richard A. Paulson KPTI Common Stock Award 136% 114,285 198,331 15 Oct 2025 Direct
Sohanya Roshan Cheng KPTI Common Stock Award 121.7% 43,650 79,506 15 Oct 2025 Direct
Lori Macomber KPTI Common Stock Award 409.2% 43,650 54,316 15 Oct 2025 Direct
Kristin Abate KPTI Common Stock Sale -3.48% $2,279 $6.30 -362 10,046 01 Oct 2025 Direct
Richard A. Paulson KPTI Common Stock Sale -1.47% $8,083 $6.43 -1,257 84,046 15 Sep 2025 Direct
Michael Mano KPTI Common Stock Sale -1.08% $1,505 $6.43 -234 21,425 15 Sep 2025 Direct
Stuart Poulton KPTI Common Stock Sale -1.43% $2,578 $6.43 -401 27,710 15 Sep 2025 Direct
Reshma Rangwala KPTI Common Stock Sale -1.37% $2,623 $6.43 -408 29,390 15 Sep 2025 Direct
Sohanya Roshan Cheng KPTI Common Stock Sale -0.9% $2,090 $6.43 -325 35,856 15 Sep 2025 Direct
Kristin Abate KPTI Common Stock Sale -0.22% $148 $6.43 -23 10,408 15 Sep 2025 Direct
Richard A. Paulson KPTI Common Stock Award 3.39% 2,800 85,303 12 Sep 2025 Direct
Michael Mano KPTI Common Stock Award 2.91% 612 21,659 12 Sep 2025 Direct
Stuart Poulton KPTI Common Stock Award 3.26% 888 28,111 12 Sep 2025 Direct
Reshma Rangwala KPTI Common Stock Award 3.28% 945 29,798 12 Sep 2025 Direct
Sohanya Roshan Cheng KPTI Common Stock Award 2.68% 945 36,181 12 Sep 2025 Direct
Kristin Abate KPTI Common Stock Award 0.44% 46 10,431 12 Sep 2025 Direct
Kristin Abate KPTI Common Stock Sale -0.13% $81.36 $6.78 -12 9,463 03 Sep 2025 Direct
Stuart Poulton KPTI Common Stock Sale -0.7% $835 $4.37 -191 27,223 29 Jul 2025 Direct
Kristin Abate KPTI Common Stock Sale -2.45% $952 $4.00 -238 9,475 22 Jul 2025 Direct
Zhen Su KPTI Nonstatutory Stock Option (right to buy) Award 4,600 4,600 28 May 2025 Direct
DEEPIKA PAKIANATHAN KPTI Nonstatutory Stock Option (right to buy) Award 4,600 4,600 28 May 2025 Direct
Christy J. Oliger KPTI Nonstatutory Stock Option (right to buy) Award 4,600 4,600 28 May 2025 Direct
Mansoor Raza Mirza KPTI Nonstatutory Stock Option (right to buy) Award 4,600 4,600 28 May 2025 Direct
Barry E. Greene KPTI Nonstatutory Stock Option (right to buy) Award 4,600 4,600 28 May 2025 Direct
Chen Schor KPTI Nonstatutory Stock Option (right to buy) Award 4,600 4,600 28 May 2025 Direct
GAREN G. BOHLIN KPTI Nonstatutory Stock Option (right to buy) Award 4,600 4,600 28 May 2025 Direct
Richard A. Paulson KPTI Common Stock Sale -0.29% $1,680 $7.12 -236 82,503 06 May 2025 Direct
Reshma Rangwala KPTI Common Stock Sale -1.43% $2,585 $6.17 -419 28,853 23 Apr 2025 Direct
Richard A. Paulson KPTI Common Stock Sale -0.3% $916 $3.74 -245 82,739 04 Apr 2025 Direct
Sohanya Roshan Cheng KPTI Common Stock Sale -9.12% -3,445 34,314 04 Mar 2025 Direct
* An asterisk sign (*) next to the price indicates that the price is likely invalid.