| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Paulson Richard A. | President and CEO, Director | C/O KARYOPHARM THERAPEUTICS INC., 85 WELLS AVENUE, NEWTON | /s/ Nancy Smith as Attorney-in-Fact for Richard Paulson | 09 Feb 2026 | 0001804460 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | KPTI | Common Stock | Award | $0 | +81,060 | +41% | $0.000000 | 279,391 | 05 Feb 2026 | Direct | F1 |
| Id | Content |
|---|---|
| F1 | Represents the award of restricted stock units ("RSUs") pursuant to the Karyopharm Therapeutics Inc. 2022 Equity Incentive Plan, as amended. RSUs convert into Karyopharm Therapeutics Inc. common stock on a one-for-one basis. The RSUs vest as to 50% of the shares on January 31, 2027, with the remaining 50% vesting on January 31, 2028. |