| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Rangwala Reshma | EVP & Chief Medical Officer | C/O KARYOPHARM THERAPEUTICS INC., 85 WELLS AVENUE, NEWTON | /s/Nancy Smith as Attorney-in-Fact for Reshma Rangwala | 03 Feb 2026 | 0001825322 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | KPTI | Common Stock | Award | $0 | +32,415 | +110% | $0.000000 | 61,805 | 31 Jan 2026 | Direct | F1 |
| Id | Content |
|---|---|
| F1 | Represents the award of restricted stock units ("RSUs") pursuant to the Karyopharm Therapeutics Inc. 2022 Equity Incentive Plan, as amended (the "2022 Plan"). RSUs convert into Karyopharm Therapeutics Inc. common stock on a one-for-one basis. The RSUs vest as to 50% of the shares on January 31, 2027, with the remaining 50% vesting on January 31, 2028. |