| Reporting Name | Ownership % | Change | Value $ | Shares owned | Change | Activity % | Price | Form | Report date | Filing time |
|---|---|---|---|---|---|---|---|---|---|---|
| Baker Bros. Advisors LP | 8.9% | $360,984,750 | 5,604,483 | $64.41 | 13G/A | 31 Mar 2025 | 15 May 2025, 16:19 |
| Holdings date | Option | Weight | Change | Value $ | Shares | Change | Activity % | Price | All Holders |
|---|---|---|---|---|---|---|---|---|---|
| 31 Dec 2025 | 3.5% | 0% | $599,903,860 | 5,604,483 | 0 | $107.04 | Q4 2025 | ||
| 30 Sep 2025 | 4.1% | 0% | $565,996,738 | 5,604,483 | 0 | $100.99 | Q3 2025 | ||
| 30 Jun 2025 | 3.4% | 0% | $354,147,281 | 5,604,483 | 0 | $63.19 | Q2 2025 | ||
| 31 Mar 2025 | 3.3% | -0.28% | $296,869,465 | 5,604,483 | -479,766 | $52.97 | Q1 2025 | ||
| 31 Dec 2024 | 3.6% | -0.19% | $340,596,259 | 6,084,249 | -314,117 | -4.9% | $55.98 | Q4 2024 | |
| 30 Sep 2024 | 3.5% | +0% | $335,210,395 | 6,398,366 | +1 | +0% | $52.39 | Q3 2024 | |
| 30 Jun 2024 | 3.4% | 0% | $262,716,867 | 6,398,365 | 0 | $41.06 | Q2 2024 | ||
| 31 Mar 2024 | 3.5% | 0% | $277,241,155 | 6,398,365 | 0 | $43.33 | Q1 2024 | ||
| 31 Dec 2023 | 3.3% | -0.16% | $294,132,839 | 6,398,365 | -303,984 | -4.5% | $45.97 | Q4 2023 | |
| 30 Sep 2023 | 0.89% | +0.03% | $153,651,351 | 6,702,349 | +204,082 | +3.1% | $22.93 | Q3 2023 | |
| 30 Jun 2023 | 0.62% | 0% | $107,156,423 | 6,498,267 | 0 | $16.49 | Q2 2023 | ||
| 31 Mar 2023 | 0.63% | +0.01% | $115,929,083 | 6,498,267 | +143,659 | +2.3% | $17.84 | Q1 2023 | |
| 31 Dec 2022 | 1.1% | +0.05% | $185,046,185 | 6,354,608 | +291,906 | +4.8% | $29.12 | Q4 2022 | |
| 30 Sep 2022 | 0.97% | +0.31% | $148,536,000 | 6,062,702 | +1,937,640 | +47% | $24.50 | Q3 2022 | |
| 30 Jun 2022 | 0.1% | 0% | $17,119,000 | 4,125,062 | 0 | $4.15 | Q2 2022 | ||
| 31 Mar 2022 | 0.27% | +0.02% | $47,521,000 | 4,125,062 | +261,823 | +6.8% | $11.52 | Q1 2022 | |
| 31 Dec 2021 | 0.19% | 0% | $38,555,000 | 3,863,239 | 0 | $9.98 | Q4 2021 | ||
| 30 Sep 2021 | 0.22% | 0% | $50,454,000 | 3,863,239 | 0 | $13.06 | Q3 2021 | ||
| 30 Jun 2021 | 0.33% | +0.03% | $75,642,000 | 3,863,239 | +383,366 | +11% | $19.58 | Q2 2021 | |
| 31 Mar 2021 | 0.32% | +0.11% | $74,017,000 | 3,479,873 | +1,165,000 | +50% | $21.27 | Q1 2021 | |
| 31 Dec 2020 | 0.26% | -0.02% | $68,821,000 | 2,314,873 | -156,282 | -6.3% | $29.73 | Q4 2020 | |
| 30 Sep 2020 | 0.21% | -0.02% | $53,550,000 | 2,471,155 | -228,900 | -8.5% | $21.67 | Q3 2020 | |
| 30 Jun 2020 | 0.27% | -0% | $60,211,000 | 2,700,055 | -8,145 | -0.3% | $22.30 | Q2 2020 | |
| 31 Mar 2020 | 0.25% | 0% | $41,219,000 | 2,708,200 | 0 | $15.22 | Q1 2020 | ||
| 31 Dec 2019 | 0.33% | 0% | $62,180,000 | 2,708,200 | 0 | $22.96 | Q4 2019 | ||
| 30 Sep 2019 | 0.4% | 0% | $58,470,000 | 2,708,200 | 0 | $21.59 | Q3 2019 | ||
| 30 Jun 2019 | 0.4% | 0% | $59,580,000 | 2,708,200 | 0 | $22.00 | Q2 2019 | ||
| 31 Mar 2019 | 0.48% | 0% | $74,232,000 | 2,708,200 | 0 | $27.41 | Q1 2019 | ||
| 31 Dec 2018 | 0.6% | 0% | $72,796,000 | 2,708,200 | 0 | $26.88 | Q4 2018 | ||
| 30 Sep 2018 | 0.52% | 0% | $78,998,000 | 2,708,200 | 0 | $29.17 | Q3 2018 | ||
| 30 Jun 2018 | 0.64% | +0.15% | $84,658,000 | 2,708,200 | +659,180 | +32% | $31.26 | Q2 2018 | |
| 31 Mar 2018 | 0.35% | 0% | $40,775,000 | 2,049,020 | 0 | $19.90 | Q1 2018 | ||
| 31 Dec 2017 | 0.52% | +0.52% | $59,545,000 | 2,049,020 | +2,049,020 | NEW | $29.06 | Q4 2017 |