RHYTHM PHARMACEUTICALS, INC. - Common Stock, $0.001 par value per share (RYTM)
CUSIP: 76243J105
Q3 2025 13F Holders as of 30 Sep 2025
- Type / Class
- Equity / Common Stock, $0.001 par value per share
- Shares outstanding
- 69,012,275
- Total 13F shares
- 70,886,984
- Share change
- +4,233,517
- Total reported value
- $7,158,776,142
- Put/Call ratio
- 30%
- Price per share
- $100.99
- Number of holders
- 263
- Value change
- +$449,472,938
- Number of buys
- 153
- Number of sells
- 98
Quarterly Holders Quick Answers
What is CUSIP 76243J105?
CUSIP 76243J105 identifies RYTM - RHYTHM PHARMACEUTICALS, INC. - Common Stock, $0.001 par value per share in SEC institutional holdings data.
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Recent filing periods for CUSIP 76243J105:
Top shareholders of RYTM - RHYTHM PHARMACEUTICALS, INC. - Common Stock, $0.001 par value per share (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.
Methodology: rows are grouped by holder and ranked by the holder's primary source value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
| Holder | Source | Role / Reporting | Ownership % | Shares | Holdings Value | 12M Net Δ | As of | Details |
|---|---|---|---|---|---|---|---|---|
| BlackRock, Inc. |
13F
13D/G
|
Company |
6.9%
from 13D/G
|
6,267,538
|
$396,045,725 | — | 30 Jun 2025 | |
| BAKER BROS. ADVISORS LP |
13D/G
13F
|
Company |
8.9%
|
5,604,483
|
$360,984,750 | $0 | 31 Mar 2025 | |
| RA CAPITAL MANAGEMENT, L.P. |
13F
|
Company |
8.1%
|
5,561,359
|
$351,422,275 | — | 30 Jun 2025 | |
| PRIMECAP MANAGEMENT CO/CA/ |
13F
|
Company |
7.1%
|
4,878,037
|
$308,243,159 | — | 30 Jun 2025 | |
| VANGUARD GROUP INC |
13F
|
Company |
5.2%
|
3,589,114
|
$226,796,115 | — | 30 Jun 2025 | |
| NEA Management Company, LLC |
13F
|
Company |
4.2%
|
2,909,956
|
$183,880,120 | — | 30 Jun 2025 | |
| PERCEPTIVE ADVISORS LLC |
13F
|
Company |
3.5%
|
2,418,299
|
$152,812,314 | — | 30 Jun 2025 | |
| FMR LLC |
13F
|
Company |
2.8%
|
1,953,441
|
$123,437,950 | — | 30 Jun 2025 | |
| STATE STREET CORP |
13F
|
Company |
2.8%
|
1,907,601
|
$120,541,307 | — | 30 Jun 2025 | |
| GOLDMAN SACHS GROUP INC |
13D/G
13F
|
THE GOLDMAN SACHS GROUP, INC. · Company |
3%
|
1,818,932
|
$117,157,406 | $0 | 31 Dec 2024 | |
| FEDERATED HERMES, INC. |
13F
|
Company |
2.4%
|
1,686,494
|
$106,569,556 | — | 30 Jun 2025 | |
| WESTFIELD CAPITAL MANAGEMENT CO LP |
13F
|
Company |
2.4%
|
1,629,468
|
$102,966,083 | — | 30 Jun 2025 | |
| JANUS HENDERSON GROUP PLC |
13F
|
Company |
2%
|
1,411,902
|
$89,265,146 | — | 30 Jun 2025 | |
| PRICE T ROWE ASSOCIATES INC /MD/ |
13F
|
Company |
1.9%
|
1,341,392
|
$84,764,000 | — | 30 Jun 2025 | |
| GEODE CAPITAL MANAGEMENT, LLC |
13F
|
Company |
1.9%
|
1,311,253
|
$82,868,422 | — | 30 Jun 2025 | |
| DRIEHAUS CAPITAL MANAGEMENT LLC |
13F
|
Company |
1.8%
|
1,269,952
|
$80,248,267 | — | 30 Jun 2025 | |
| Polar Capital Holdings Plc |
13F
|
Company |
1.8%
|
1,250,870
|
$79,042,475 | — | 30 Jun 2025 | |
| Checkpoint Capital L.P. |
13F
|
Company |
1.5%
|
1,060,000
|
$66,981,400 | — | 30 Jun 2025 | |
| ALKEON CAPITAL MANAGEMENT LLC |
13F
|
Company |
1.5%
|
1,017,700
|
$64,308,463 | — | 30 Jun 2025 | |
| Rock Springs Capital Management LP |
13F
|
Company |
1.2%
|
861,153
|
$54,416,258 | — | 30 Jun 2025 | |
| JPMORGAN CHASE & CO |
13F
|
Company |
1.1%
|
783,559
|
$49,513,092 | — | 30 Jun 2025 | |
| LOOMIS SAYLES & CO L P |
13F
|
Company |
0.86%
|
591,454
|
$37,373,978 | — | 30 Jun 2025 | |
| Sofinnova Investments, Inc. |
13F
|
Company |
0.85%
|
586,010
|
$37,029,972 | — | 30 Jun 2025 | |
| FRANKLIN RESOURCES INC |
13F
|
Company |
0.79%
|
543,802
|
$34,362,849 | — | 30 Jun 2025 | |
| Hood River Capital Management LLC |
13F
|
Company |
0.79%
|
543,688
|
$34,355,645 | — | 30 Jun 2025 | |
| MORGAN STANLEY |
13F
|
Company |
0.76%
|
524,480
|
$33,141,973 | — | 30 Jun 2025 | |
| Woodline Partners LP |
13F
|
Company |
0.75%
|
514,381
|
$32,503,735 | — | 30 Jun 2025 | |
| NORTHERN TRUST CORP |
13F
|
Company |
0.74%
|
510,246
|
$32,242,444 | — | 30 Jun 2025 | |
| Opaleye Management Inc. |
13F
|
Company |
0.69%
|
475,000
|
$30,015,250 | — | 30 Jun 2025 | |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
13F
|
Company |
0.67%
|
461,438
|
$29,158,267 | — | 30 Jun 2025 | |
| Pictet Asset Management Holding SA |
13F
|
Company |
0.6%
|
416,115
|
$26,258,533 | — | 30 Jun 2025 | |
| Siren, L.L.C. |
13F
|
Individual |
0.59%
|
409,742
|
$25,891,597 | — | 30 Jun 2025 | |
| SILVERARC CAPITAL MANAGEMENT, LLC |
13F
|
Company |
0.58%
|
400,772
|
$25,324,783 | — | 30 Jun 2025 | |
| MARSHALL WACE, LLP |
13F
|
Company |
0.55%
|
376,242
|
$23,774,732 | — | 30 Jun 2025 | |
| BARCLAYS PLC |
13F
|
Company |
0.51%
|
351,198
|
$22,192,201 | — | 30 Jun 2025 | |
| ADAGE CAPITAL PARTNERS GP, L.L.C. |
13F
|
Company |
0.49%
|
341,000
|
$21,547,790 | — | 30 Jun 2025 | |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC |
13F
|
Company |
0.49%
|
338,804
|
$21,409,025 | — | 30 Jun 2025 | |
| RENAISSANCE TECHNOLOGIES LLC |
13F
|
Company |
0.46%
|
314,893
|
$19,898,089 | — | 30 Jun 2025 | |
| S.c.a. Candriam |
13F
|
Individual |
0.45%
|
312,452
|
$19,744,683 | — | 30 Jun 2025 | |
| Clearbridge Investments, LLC |
13F
|
Company |
0.45%
|
312,445
|
$19,743,403 | — | 30 Jun 2025 | |
| COMERICA BANK |
13F
|
Company |
0.44%
|
301,661
|
$19,061,978 | — | 30 Jun 2025 | |
| UBS Group AG |
13F
|
Company |
0.37%
|
252,582
|
$15,960,656 | — | 30 Jun 2025 | |
| ORBIMED ADVISORS LLC |
13F
|
Company |
0.36%
|
248,512
|
$15,703,473 | — | 30 Jun 2025 | |
| VOYA INVESTMENT MANAGEMENT LLC |
13F
|
Company |
0.35%
|
244,003
|
$15,418,550 | — | 30 Jun 2025 | |
| Qube Research & Technologies Ltd |
13F
|
Company |
0.35%
|
240,345
|
$15,187,401 | — | 30 Jun 2025 | |
| Assenagon Asset Management S.A. |
13F
|
Company |
0.34%
|
237,998
|
$15,039,094 | — | 30 Jun 2025 | |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
13F
|
Company |
0.33%
|
227,627
|
$14,383,750 | — | 30 Jun 2025 | |
| BANK OF AMERICA CORP /DE/ |
13F
|
Company |
0.32%
|
222,152
|
$14,037,784 | — | 30 Jun 2025 | |
| NORGES BANK |
13F
|
Company |
0.3%
|
207,389
|
$13,104,911 | — | 30 Jun 2025 | |
| LORD, ABBETT & CO. LLC |
13F
|
Company |
0.3%
|
204,275
|
$12,908,000 | — | 30 Jun 2025 |
Institutional Holders of RHYTHM PHARMACEUTICALS, INC. - Common Stock, $0.001 par value per share (RYTM) as of Q3 2025
As of 30 Sep 2025,
RHYTHM PHARMACEUTICALS, INC. - Common Stock, $0.001 par value per share (RYTM) was held by
263 institutional
shareholders
that filed Form 13F with the SEC.
Together, they reported ownership of
70,886,984 shares.
The largest 10 holders included
BlackRock, Inc., RA CAPITAL MANAGEMENT, L.P., BAKER BROS. ADVISORS LP, VANGUARD GROUP INC, PRIMECAP MANAGEMENT CO/CA/, NEA Management Company, LLC, PERCEPTIVE ADVISORS LLC, FMR LLC, STATE STREET CORP, and GOLDMAN SACHS GROUP INC.
This page lists
263
institutional shareholders reporting positions in this security
for the Q3 2025 filing period.
| Investor | Option | Weight % | Change % | Value $ | * Price | Shares | Share Change | Activity | Report Period |
|---|
Compare Q3 2025 vs Q2 2025 Across Filers
Q2 2025 holders
225
Q3 2025 holders
263
Holder diff
38
| Investor | Q2 2025 Shares | Q3 2025 Shares | Share Diff | Share Chg % | Q2 2025 Value $ | Q3 2025 Value $ | Value Diff $ | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).
Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
An asterisk sign (*) next to the price indicates that the price is likely invalid.