RHYTHM PHARMACEUTICALS, INC. - Common Stock, $0.001 par value per share (RYTM)

Q: What does CUSIP 76243J105 represent in this 13F holders report?

CUSIP 76243J105 is the security identifier for RYTM - RHYTHM PHARMACEUTICALS, INC. - Common Stock, $0.001 par value per share used to aggregate holder disclosures.

Q: How many institutions held RYTM - RHYTHM PHARMACEUTICALS, INC. - Common Stock, $0.001 par value per share in Q1 2021?

119 institutional investors reported RYTM - RHYTHM PHARMACEUTICALS, INC. - Common Stock, $0.001 par value per share for Q1 2021. Use the holders table for investor-level position and value details.

CUSIP: 76243J105

Q1 2021 13F Holders as of 31 Mar 2021

Security type / class: Equity / Common Stock, $0.001 par value per share
Total 13F shares: 47,577,014
Total 13F value: $1,011,965,096
Share change: +7,043,914
Put/Call ratio: 200%
SEC-reported price per share: $21.27
Number of holders: 119
Value change: +$147,271,703
Number of buys: 75
Number of sells: 42
Shares outstanding: 69,012,275

Security key

76243J105

Report period

Q1 2021

Institutions

119

Top holders

RYTM full security history Ownership snapshot Full 13F holder table Newer quarter: Q2 2021 Previous quarter: Q4 2020 RHYTHM PHARMACEUTICALS, INC. SEC filings RHYTHM PHARMACEUTICALS, INC. company facts

Broader feeds

Latest 13F filings Latest 13D/G filings Investors directory

Reporting periods

Holder history for CUSIP 76243J105

Newer quarter: Q2 2021 Previous quarter: Q4 2020

Recent filing periods:

Q1 2026 Q4 2025 Q3 2025 Q2 2025 Q1 2025 Q4 2024 Q3 2024 Q2 2024

Ownership snapshot

Top reported holders of RYTM - RHYTHM PHARMACEUTICALS, INC. - Common Stock, $0.001 par value per share (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader

NEA Management Company, LLC

Disclosed value leader

NEA Management Company, LLC

Comparable rows

15/15

Latest evidence

31 Dec 2020

13F Lead comparable stake: 7.1% Showing 1-6 of 15 holder rows.

Quick read

NEA Management Company, LLC leads the comparable SEC ownership view at 7.1%.

15 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens NEA Management Company, LLC's linked filing trail.

Comparable ownership Top 5

NEA Management Company, LLC 7.1%

JANUS HENDERSON GROUP PLC 6.5%

PRIMECAP MANAGEMENT CO/CA/ 6.3%

RA CAPITAL MANAGEMENT, L.P. 6.1%

BlackRock Finance, Inc. 4%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-6 of 15 holder rows

Holder	Evidence	Ownership %	Position	12M Net Δ	As of
NEA Management Company, LLC	13F Company 13F	7.1%	$142,948,000 4,912,306 shares	—	31 Dec 2020
JANUS HENDERSON GROUP PLC	13F Company 13F	6.5%	$133,542,000 4,491,765 shares	—	31 Dec 2020
PRIMECAP MANAGEMENT CO/CA/	13F Company 13F	6.3%	$129,102,000 4,342,491 shares	—	31 Dec 2020
RA CAPITAL MANAGEMENT, L.P.	13F Company 13F	6.1%	$124,244,000 4,179,067 shares	—	31 Dec 2020
BlackRock Finance, Inc.	13F Company 13F	4%	$81,195,000 2,731,106 shares	—	31 Dec 2020
DEERFIELD MANAGEMENT COMPANY, L.P.	13F Company 13F	3.9%	$80,901,000 2,721,203 shares	—	31 Dec 2020

How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

13F holder rows

Institutional holders as of Q1 2021

Investor-level positions for this CUSIP, loaded as an interactive table.

Institutions

119

47,577,014

Rows available

119

Investor	Option	Weight %	Change %	SEC-reported value	* Price	Shares	Share Change	Activity	Report Period

^* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.

Compare Q1 2021 vs Q4 2020 Across Filers

Q4 2020 holders

114

Q1 2021 holders

119

Holder diff

Investor	Q4 2020 Shares	Q1 2021 Shares	Share Diff	Share Chg %	Q4 2020 value	Q1 2021 value	Value change	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend