RHYTHM PHARMACEUTICALS, INC. - Common Stock, $0.001 par value per share (RYTM)

Q: What does CUSIP 76243J105 represent in this 13F holders report?

CUSIP 76243J105 is the security identifier for RYTM - RHYTHM PHARMACEUTICALS, INC. - Common Stock, $0.001 par value per share used to aggregate holder disclosures.

Q: How many institutions held RYTM - RHYTHM PHARMACEUTICALS, INC. - Common Stock, $0.001 par value per share in Q2 2022?

82 institutional investors reported RYTM - RHYTHM PHARMACEUTICALS, INC. - Common Stock, $0.001 par value per share for Q2 2022. Use the holders table for investor-level position and value details.

CUSIP: 76243J105

Q2 2022 13F Holders as of 30 Jun 2022

Security type / class: Equity / Common Stock, $0.001 par value per share
Total 13F shares: 45,934,145
Total 13F value: $190,627,988
Share change: -2,876,768
Put/Call ratio: 0%
SEC-reported price per share: $4.15
Number of holders: 82
Value change: -$18,795,957
Number of buys: 38
Number of sells: 62
Shares outstanding: 69,012,275

Security key

76243J105

Report period

Q2 2022

Institutions

Top holders

RYTM full security history Ownership snapshot Full 13F holder table Newer quarter: Q3 2022 Previous quarter: Q1 2022 RHYTHM PHARMACEUTICALS, INC. SEC filings RHYTHM PHARMACEUTICALS, INC. company facts

Broader feeds

Latest 13F filings Latest 13D/G filings Investors directory

Reporting periods

Holder history for CUSIP 76243J105

Newer quarter: Q3 2022 Previous quarter: Q1 2022

Recent filing periods:

Q1 2026 Q4 2025 Q3 2025 Q2 2025 Q1 2025 Q4 2024 Q3 2024 Q2 2024

Ownership snapshot

Top reported holders of RYTM - RHYTHM PHARMACEUTICALS, INC. - Common Stock, $0.001 par value per share (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader

PRIMECAP MANAGEMENT CO/CA/

Disclosed value leader

PRIMECAP MANAGEMENT CO/CA/

Comparable rows

15/15

Latest evidence

31 Mar 2022

13F Lead comparable stake: 9.1% Showing 1-6 of 15 holder rows.

Quick read

PRIMECAP MANAGEMENT CO/CA/ leads the comparable SEC ownership view at 9.1%.

15 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens PRIMECAP MANAGEMENT CO/CA/'s linked filing trail.

Comparable ownership Top 5

PRIMECAP MANAGEMENT CO/CA/ 9.1%

FEDERATED HERMES, INC. 7.3%

NEA Management Company, LLC 7.1%

RA CAPITAL MANAGEMENT, L.P. 7.1%

BAKER BROS. ADVISORS LP 6%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-6 of 15 holder rows

Holder	Evidence	Ownership %	Position	12M Net Δ	As of
PRIMECAP MANAGEMENT CO/CA/	13F Company 13F	9.1%	$72,484,000 6,291,991 shares	—	31 Mar 2022
FEDERATED HERMES, INC.	13F Company 13F	7.3%	$58,350,000 5,065,113 shares	—	31 Mar 2022
NEA Management Company, LLC	13F Company 13F	7.1%	$56,590,000 4,912,306 shares	—	31 Mar 2022
RA CAPITAL MANAGEMENT, L.P.	13F Company 13F	7.1%	$56,115,000 4,871,067 shares	—	31 Mar 2022
BAKER BROS. ADVISORS LP	13F Company 13F	6%	$47,521,000 4,125,062 shares	—	31 Mar 2022
GOLDMAN SACHS GROUP INC	13F Company 13F	4.8%	$38,474,000 3,339,750 shares	—	31 Mar 2022

How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

13F holder rows

Institutional holders as of Q2 2022

Investor-level positions for this CUSIP, loaded as an interactive table.

Institutions

45,934,145

Rows available

Investor	Option	Weight %	Change %	SEC-reported value	* Price	Shares	Share Change	Activity	Report Period

^* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.

Compare Q2 2022 vs Q1 2022 Across Filers

Q1 2022 holders

105

Q2 2022 holders

Holder diff

-23

Investor	Q1 2022 Shares	Q2 2022 Shares	Share Diff	Share Chg %	Q1 2022 value	Q2 2022 value	Value change	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend